Articles

Publications



Transcriptome landscape of Lactococcus lactis reveals many novel RNAs including a small regulatory RNA involved in carbon uptake and metabolism. van der Meulen SB; de Jong A; Kok J RNA Biol 2016 ;13(3):353-66
pubmedlink 26950529

2016

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Plasmid Complement of Lactococcus lactis NCDO712 Reveals a Novel Pilus Gene Cluster. Tarazanova M; Beerthuyzen M; Siezen R; Fernandez-Gutierrez MM; de Jong A; van der Meulen S; Kok J; Bachmann H PLoS One 2016 ;11(12):0-0
pubmedlink 27941999

2016

Cysteine-Mediated Gene Expression and Characterization of the CmbR Regulon in Streptococcus pneumoniae. Afzal M; Manzoor I; Kuipers OP; Shafeeq S Front Microbiol 2016 ;7(0):1929-0
pubmedlink 27990139

2016

High-Level Heat Resistance of Spores of Bacillus amyloliquefaciens and Bacillus licheniformis Results from the Presence of a spoVA Operon in a Tn1546 Transposon. Berendsen EM; Koning RA; Boekhorst J; de Jong A; Kuipers OP; Wells-Bennik MH Front Microbiol 2016 ;7(0):1912-0
pubmedlink 27994575

2016

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Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation. Sorg RA; Lin L; van Doorn GS; Sorg M; Olson J; Nizet V; Veening JW PLoS Biol 2016 ;14(12):0-0
pubmedlink 28027306

2016

Development of an efficient electroporation method for rhizobacterial Bacillus mycoides strains. Yi Y; Kuipers OP J Microbiol Methods 2016 ;133(0):82-86
pubmedlink 28042055

2016

On the Spatial Organization of mRNA, Plasmids, and Ribosomes in a Bacterial Host Overexpressing Membrane Proteins. van Gijtenbeek LA; Robinson A; van Oijen AM; Poolman B; Kok J PLoS Genet 2016 ;12(12):0-0
pubmedlink 27977669

2016

Expression of prophage-encoded endolysins contributes to autolysis of Lactococcus lactis. Visweswaran GR; Kurek D; Szeliga M; Pastrana FR; Kuipers OP; Kok J; Buist G Appl Microbiol Biotechnol 2016 ;0(0):0-0
pubmedlink 27660179

2016

N-acetylgalatosamine-Mediated Regulation of the aga Operon by AgaR in Streptococcus pneumoniae. Afzal M; Shafeeq S; Ahmed H; Kuipers OP Front Cell Infect Microbiol 2016 ;6(0):101-0
pubmedlink 27672623

2016

Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection. Aprianto R; Slager J; Holsappel S; Veening JW Genome Biol 2016 ;17(1):198-0
pubmedlink 27678244

2016

Identification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity Environments Using RNA Sequencing. Nagler K; Krawczyk AO; De Jong A; Madela K; Hoffmann T; Laue M; Kuipers OP; Bremer E; Moeller R Front Microbiol 2016 ;7(0):1564-0
pubmedlink 27766092

2016

SpoVT: From Fine-Tuning Regulator in Bacillus subtilis to Essential Sporulation Protein in Bacillus cereus. Eijlander RT; Holsappel S; de Jong A; Ghosh A; Christie G; Kuipers OP Front Microbiol 2016 ;7(0):1607-0
pubmedlink 27790204

2016

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Draft Genome Sequences of Two Geobacillus Species Strains, Isolated from Oil Wells and Surface Soil above Oil Pools. Kaunietis A; de Jong A; Pranckute R; Buivydas A; Kuipers OP Genome Announc 2016 ;4(5):0-0
pubmedlink 27795271

2016

Identification and classification of known and putative antimicrobial compounds produced by a wide variety of Bacillales species. Zhao X; Kuipers OP BMC Genomics 2016 ;17(1):882-0
pubmedlink 27821051

2016

Employing the promiscuity of lantibiotic biosynthetic machineries to produce novel antimicrobials. Montalban-Lopez M; van Heel AJ; Kuipers OP FEMS Microbiol Rev 2016 ;0(0):0-0
pubmedlink 27591436

2016

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Posttranslational Peptide-Modification Enzymes in Action: Key Roles for Leaders and Glutamate. Montalban-Lopez M; Kuipers OP Cell Chem Biol 2016 ;23(3):318-9
pubmedlink 26991100

2016

Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis. Solopova A; Formosa-Dague C; Courtin P; Furlan S; Veiga P; Pechoux C; Armalyte J; Sadauskas M; Kok J; Hols P; Dufrene YF; Kuipers OP; Chapot-Chartier MP; Kulakauskas S J Biol Chem 2016 ;291(21):11323-36
pubmedlink 27022026

2016

A mobile genetic element profoundly increases heat resistance of bacterial spores. Berendsen EM; Boekhorst J; Kuipers OP; Wells-Bennik MH ISME J 2016 ;10(11):2633-2642
pubmedlink 27105070

2016

A putative amino acid transporter determines sensitivity to the two-peptide bacteriocin plantaricin JK. Oppegard C; Kjos M; Veening JW; Nissen-Meyer J; Kristensen T Microbiologyopen 2016 ;5(4):700-8
pubmedlink 27150273

2016

Draft Genome Sequences of Seven Thermophilic Spore-Forming Bacteria Isolated from Foods That Produce Highly Heat-Resistant Spores, Comprising Geobacillus spp., Caldibacillus debilis, and Anoxybacillus flavithermus. Berendsen EM; Wells-Bennik MH; Krawczyk AO; de Jong A; van Heel A; Holsappel S; Eijlander RT; Kuipers OP Genome Announc 2016 ;4(3):0-0
pubmedlink 27151781

2016

Genome Sequences of 12 Spore-Forming Bacillus Species, Comprising Bacillus coagulans, Bacillus licheniformis, Bacillus amyloliquefaciens, Bacillus sporothermodurans, and Bacillus vallismortis, Isolated from Foods. Krawczyk AO; de Jong A; Holsappel S; Eijlander RT; van Heel A; Berendsen EM; Wells-Bennik MH; Kuipers OP Genome Announc 2016 ;4(3):0-0
pubmedlink 27174261

2016

A transposon present in specific strains of Bacillus subtilis negatively affects nutr Krawczyk AO; Berendsen EM; de Jong A; Boekhorst J; Wells-Bennik MH; Kuipers OP; Eijlander RT Environ Microbiol 2016 ;0(0):0-0
pubmedlink 27234229

2016

Draft Whole-Genome Sequences of 11 Bacillus cereus Food Isolates. Hayrapetyan H; Boekhorst J; de Jong A; Kuipers OP; Nierop Groot MN; Abee T Genome Announc 2016 ;4(3):0-0
pubmedlink 27257202

2016

The impact of manganese on biofilm development of Bacillus subtilis. Mhatre E; Troszok A; Gallegos-Monterrosa R; Lindstadt S; Holscher T; Kuipers OP; Kovacs AT Microbiology 2016 ;0(0):0-0
pubmedlink 27267987

2016

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model. Jim KK; Engelen-Lee J; van der Sar AM; Bitter W; Brouwer MC; van der Ende A; Veening JW; van de Beek D; Vandenbroucke-Grauls CM J Neuroinflammation 2016 ;13(1):188-0
pubmedlink 27542968

2016

Linking Bacillus cereus Genotypes and Carbohydrate Utilization Capacity. Warda AK; Siezen RJ; Boekhorst J; Wells-Bennik MH; de Jong A; Kuipers OP; Nierop Groot MN; Abee T PLoS One 2016 ;11(6):0-0
pubmedlink 27272929

2016

Discovery, Production and Modification of Five Novel Lantibiotics Using the Promiscuous Nisin Modification Machinery. van Heel AJ; Kloosterman TG; Montalban-Lopez M; Deng J; Plat A; Baudu B; Hendriks D; Moll GN; Kuipers OP ACS Synth Biol 2016 ;0(0):0-0
pubmedlink 27294279

2016

Draft Whole-Genome Sequences of Three Lactobacillus plantarum Food Isolates. Fernandez Ramirez MD; Boekhorst J; de Jong A; Kuipers OP; Abee T; Nierop Groot MN Genome Announc 2016 ;4(3):0-0
pubmedlink 27313301

2016

Hard-Wired Control of Bacterial Processes by Chromosomal Gene Location. Slager J; Veening JW Trends Microbiol 2016 ;0(0):0-0
pubmedlink 27364121

2016

Transcriptome profiling of TDC cluster deletion mutant of Enterococcus faecalis V583. Perez M; Ladero V; Del Rio B; Redruello B; de Jong A; Kuipers OP; Kok J; Martin MC; Fernandez M; Alvarez MA Genom Data 2016 ;9(0):67-9
pubmedlink 27408815

2016

YsbA and LytST are essential for pyruvate utilization in Bacillus subtilis. van den Esker MH; Kovacs AT; Kuipers OP Environ Microbiol 2016 ;0(0):0-0
pubmedlink 27422364

2016

Stress Physiology of Lactic Acid Bacteria. Papadimitriou K; Alegria A; Bron PA; de Angelis M; Gobbetti M; Kleerebezem M; Lemos JA; Linares DM; Ross P; Stanton C; Turroni F; van Sinderen D; Varmanen P; Ventura M; Zuniga M; Tsakalidou E; Kok J Microbiol Mol Biol Rev 2016 ;80(3):837-90
pubmedlink 27466284

2016

Lantibiotic Reductase LtnJ Substrate Selectivity Assessed with a Collection of Nisin Derivatives as Substrates. Mu D; Montalban-Lopez M; Deng J; Kuipers OP Appl Environ Microbiol 2015 ;81(11):3679-87
pubmedlink 25795677

2015

The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae. Attaiech L; Minnen A; Kjos M; Gruber S; Veening JW MBio 2015 ;6(4):0-0
pubmedlink 26126852

2015

A fluorescence-based bioassay for antibacterials and its application in screening natural product extracts. Michels K; Heinke R; Schone P; Kuipers OP; Arnold N; Wessjohann LA J Antibiot (Tokyo) 2015 ;68(12):734-40
pubmedlink 26152282

2015

A Duo of Potassium-Responsive Histidine Kinases Govern the Multicellular Destiny of Bacillus subtilis. Grau RR; de Ona P; Kunert M; Lenini C; Gallegos-Monterrosa R; Mhatre E; Vileta D; Donato V; Holscher T; Boland W; Kuipers OP; Kovacs AT MBio 2015 ;6(4):0-0
pubmedlink 26152584

2015

Fucose-Mediated Transcriptional Activation of the fcs Operon by FcsR in Streptococcus pneumoniae. Manzoor I; Shafeeq S; Afzal M; Kuipers OP J Mol Microbiol Biotechnol 2015 ;25(2):120-8
pubmedlink 26159073

2015

Co(2+)-dependent gene expression in Streptococcus pneumoniae: opposite effect of Mn(2+) and Co(2+) on the expression of the virulence genes psaBCA, pcpA, and prtA. Manzoor I; Shafeeq S; Kloosterman TG; Kuipers OP Front Microbiol 2015 ;6(0):748-0
pubmedlink 26257722

2015

Minimum Information about a Biosynthetic Gene cluster. Medema MH; Kottmann R; Yilmaz P; Cummings M; Biggins JB; Blin K; de Bruijn I; Chooi YH; Claesen J; Coates RC; Cruz-Morales P; Duddela S; Dusterhus S; Edwards DJ; Fewer DP; Garg N; Geiger C; Gomez-Escribano JP; Greule A; Hadjithomas M; Haines AS; Helfrich EJ; Hillwig ML; Ishida K; Jones AC; Jones CS; Jungmann K; Kegler C; Kim HU; Kotter P; Krug D; Masschelein J; Melnik AV; Mantovani SM; Monroe EA; Moore M; Moss N; Nutzmann HW; Pan G; Pati A; Petras D; Reen FJ; Rosconi F; Rui Z; Tian Z; Tobias NJ; Tsunematsu Y; Wiemann P; Wyckoff E; Yan X; Yim G; Yu F; Xie Y; Aigle B; Apel AK; Balibar CJ; Balskus EP; Barona-Gomez F; Bechthold A; Bode HB; Borriss R; Brady SF; Brakhage AA; Caffrey P; Cheng YQ; Clardy J; Cox RJ; De Mot R; Donadio S; Donia MS; van der Donk WA; Dorrestein PC; Doyle S; Driessen AJ; Ehling-Schulz M; Entian KD; Fischbach MA; Gerwick L; Gerwick WH; Gross H; Gust B; Hertweck C; Hofte M; Jensen SE; Ju J; Katz L; Kaysser L; Klassen JL; Keller NP; Kormanec J; Kuipers OP; Kuzuyama T; Kyrpides NC; Kwon HJ; Lautru S; Lavigne R; Lee CY; Linquan B; Liu X; Liu W; Luzhetskyy A; Mahmud T; Mast Y; Mendez C; Metsa-Ketela M; Micklefield J; Mitchell DA; Moore BS; Moreira LM; Muller R; Neilan BA; Nett M; Nielsen J; O Nat Chem Biol 2015 ;11(9):625-31
pubmedlink 26284661

2015

T-REx: Transcriptome analysis webserver for RNA-seq Expression data. de Jong A; van der Meulen S; Kuipers OP; Kok J BMC Genomics 2015 ;16(0):663-0
pubmedlink 26335208

2015

Bacillus thermoamylovorans Spores with Very-High-Level Heat Resistance Germinate Poorly in Rich Medium despite the Presence of ger Clusters but Efficiently upon Exposure to Calcium-Dipicolinic Acid. Berendsen EM; Krawczyk AO; Klaus V; de Jong A; Boekhorst J; Eijlander RT; Kuipers OP; Wells-Bennik MH Appl Environ Microbiol 2015 ;81(22):7791-801
pubmedlink 26341201

2015

Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in Streptococcus pneumoniae. Nourikyan J; Kjos M; Mercy C; Cluzel C; Morlot C; Noirot-Gros MF; Guiral S; Lavergne JP; Veening JW; Grangeasse C PLoS Genet 2015 ;11(9):0-0
pubmedlink 26378458

2015

Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator CcpA of Bacillus subtilis. Detert Oude Weme R; Seidel G; Kuipers OP Front Microbiol 2015 ;6(0):1051-0
pubmedlink 26483775

2015

Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae. Shafeeq S; Afzal M; Henriques-Normark B; Kuipers OP Genom Data 2015 ;4(0):57-9
pubmedlink 26484177

2015

Transcriptional and metabolic effects of glucose on Streptococcus pneumoniae sugar metabolism. Paixao L; Caldas J; Kloosterman TG; Kuipers OP; Vinga S; Neves AR Front Microbiol 2015 ;6(0):1041-0
pubmedlink 26500614

2015

Next-Generation Whole-Genome Sequencing of Eight Strains of Bacillus cereus, Isolated from Food. Krawczyk AO; de Jong A; Eijlander RT; Berendsen EM; Holsappel S; Wells-Bennik MH; Kuipers OP Genome Announc 2015 ;3(6):0-0
pubmedlink 26679589

2015

Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae. Kuipers K; Gallay C; Martinek V; Rohde M; Martinkova M; van der Beek SL; Jong WS; Venselaar H; Zomer A; Bootsma H; Veening JW; de Jonge MI Mol Microbiol 2015 ;0(0):0-0
pubmedlink 26691161

2015

Transcriptome analysis of Streptococcus pneumoniae D39 in the presence of cobalt. Manzoor I; Shafeeq S; Kuipers OP Genom Data 2015 ;6(0):151-3
pubmedlink 26697359

2015

The Regulation of the AdcR Regulon in Streptococcus pneumoniae Depends Both on Zn Manzoor I; Shafeeq S; Afzal M; Kuipers OP Front Cell Infect Microbiol 2015 ;5(0):91-0
pubmedlink 26697415

2015

Ni2+-Dependent and PsaR-Mediated Regulation of the Virulence Genes pcpA, psaBCA, and prtA in Streptococcus pneumoniae. Manzoor I; Shafeeq S; Kuipers OP PLoS One 2015 ;10(11):0-0
pubmedlink 26562538

2015

Transcriptional Profile of Bacillus subtilis sigF-Mutant during Vegetative Growth. Overkamp W; Kuipers OP PLoS One 2015 ;10(10):0-0
pubmedlink 26506528

2015

Microscale insights into pneumococcal antibiotic mutant selection windows. Sorg RA; Veening JW Nat Commun 2015 ;6(0):8773-0
pubmedlink 26514094

2015

GalR Acts as a Transcriptional Activator of galKT in the Presence of Galactose in Streptococcus pneumoniae. Afzal M; Shafeeq S; Manzoor I; Kuipers OP J Mol Microbiol Biotechnol 2015 ;25(6):363-371
pubmedlink 26544195

2015

Red fluorescent proteins for gene expression and protein localization studies in Streptococcus pneumoniae and efficient transformation with Gibson assembled DNA. Beilharz K; van Raaphorst R; Kjos M; Veening JW Appl Environ Microbiol 2015 ;0(0):0-0
pubmedlink 26253684

2015

Recombinant pediocin in Lactococcus lactis: increased production by propeptide fusion and improved potency by co-production with PedC. Back A; Borges F; Mangavel C; Paris C; Rondags E; Kapel R; Aymes A; Rogniaux H; Pavlovic M; van Heel AJ; Kuipers OP; Revol-Junelles AM; Cailliez-Grimal C Microb Biotechnol 2015 ;0(0):0-0
pubmedlink 26147827

2015

AguR is a transmembrane transcription activator of the putrescine biosynthesis operon in Lactococcus lactis, and acts in response to agmatine concentration. Linares DM; Del Rio B; Redruello B; Ladero V; Martin MC; de Jong A; Kuipers OP; Fernandez M; Alvarez MA Appl Environ Microbiol 2015 ;0(0):0-0
pubmedlink 26116671

2015

Physiological and transcriptional responses of different industrial microbes at near-zero specific growth rates. Ercan O; Bisschops MM; Overkamp W; Jorgensen TR; Ram AF; Smid EJ; Pronk JT; Kuipers OP; Daran-Lapujade P; Kleerebezem M Appl Environ Microbiol 2015 ;0(0):0-0
pubmedlink 26048933

2015

Maltose-Dependent Transcriptional Regulation of the mal Regulon by MalR in Streptococcus pneumoniae. Afzal M; Shafeeq S; Manzoor I; Kuipers OP PLoS One 2015 ;10(6):0-0
pubmedlink 26030923

2015

Microbial bet-hedging: the power of being different. Grimbergen AJ; Siebring J; Solopova A; Kuipers OP Curr Opin Microbiol 2015 ;25(0):67-72
pubmedlink 26025019

2015

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae. Afzal M; Manzoor I; Kuipers OP J Vis Exp 2015 ;0(98):0-0
pubmedlink 25938895

2015

Spatio-temporal remodeling of functional membrane microdomains organizes the signaling networks of a bacterium. Schneider J; Klein T; Mielich-Suss B; Koch G; Franke C; Kuipers OP; Kovacs AT; Sauer M; Lopez D PLoS Genet 2015 ;11(4):0-0
pubmedlink 25909364

2015

Single cell FRET analysis for the identification of optimal FRET-pairs in Bacillus subtilis using a prototype MEM-FLIM system. Detert Oude Weme RG; Kovacs AT; de Jong SJ; Veening JW; Siebring J; Kuipers OP PLoS One 2015 ;10(4):0-0
pubmedlink 25886351

2015

Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect? Goel A; Eckhardt TH; Puri P; de Jong A; Branco Dos Santos F; Giera M; Fusetti F; de Vos WM; Kok J; Poolman B; Molenaar D; Kuipers OP; Teusink B Mol Microbiol 2015 ;97(1):77-92
pubmedlink 25828364

2015

Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection. Paixao L; Oliveira J; Verissimo A; Vinga S; Lourenco EC; Ventura MR; Kjos M; Veening JW; Fernandes VE; Andrew PW; Yesilkaya H; Neves AR PLoS One 2015 ;10(3):0-0
pubmedlink 25826206

2015

The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity. Zhou L; van Heel AJ; Kuipers OP Front Microbiol 2015 ;6(0):11-0
pubmedlink 25688235

2015

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Complete Genome Sequence of Bacillus amyloliquefaciens Strain BH072, Isolated from Honey. Zhao X; de Jong A; Zhou Z; Kuipers OP Genome Announc 2015 ;3(2):0-0
pubmedlink 25767235

2015

Identification of essential amino acid residues in the nisin dehydratase NisB. Khusainov R; van Heel AJ; Lubelski J; Moll GN; Kuipers OP Front Microbiol 2015 ;6(0):102-0
pubmedlink 25767464

2015

Substrate selectivity of the lantibiotic reductase LtnJ assessed by a collection of nisin derivatives as substrate. Mu D; Montalban-Lopez M; Deng J; Kuipers OP Appl Environ Microbiol 2015 ;0(0):0-0
pubmedlink 25795677

2015

Draft Genome Sequences of Four Bacillus thermoamylovorans Strains Isolated from Milk and Acacia Gum, a Food Ingredient. Krawczyk AO; Berendsen EM; Eijlander RT; de Jong A; Wells-Bennik MH; Kuipers OP Genome Announc 2015 ;3(2):0-0
pubmedlink 25814599

2015

Draft Genome Sequences of Five Spore-Forming Food Isolates of Bacillus pumilus. de Jong A; van Heel AJ; Montalban-Lopez M; Krawczyk AO; Berendsen EM; Wells-Bennik M; Kuipers OP Genome Announc 2015 ;3(2):0-0
pubmedlink 25767247

2015

Bacillus subtilis biosensor engineered to assess meat spoilage. Daszczuk A; Dessalegne Y; Drenth I; Hendriks E; Jo E; van Lente T; Oldebesten A; Parrish J; Poljakova W; Purwanto AA; van Raaphorst R; Boonstra M; van Heel A; Herber M; van der Meulen S; Siebring J; Sorg RA; Heinemann M; Kuipers OP; Veening JW ACS Synth Biol 2014 ;3(12):999-1002
pubmedlink 25524109

2014

Ascorbic acid-dependent gene expression in Streptococcus pneumoniae and the activator function of the transcriptional regulator UlaR2. Afzal M; Shafeeq S; Kuipers OP Front Microbiol 2015 ;6(0):72-0
pubmedlink 25717320

2015

Sialic acid-mediated gene expression in Streptococcus pneumoniae and the role of NanR as a transcriptional activator of the nan gene cluster. Afzal M; Shafeeq S; Ahmed H; Kuipers OP Appl Environ Microbiol 2015 ;0(0):0-0
pubmedlink 25724955

2015

Two distinct groups within the Bacillus subtilis group display significantly different spore heat resistance properties. Berendsen EM; Zwietering MH; Kuipers OP; Wells-Bennik MH Food Microbiol 2015 ;45(0):18-25
pubmedlink 25481058

2015

Back to Nature: a revival of natural strain improvement methodologies. Kuipers OP Microb Biotechnol 2015 ;8(1):17-8
pubmedlink 25488414

2015

Bright fluorescent Streptococcus pneumoniae for live cell imaging of host-pathogen interactions. Kjos M; Aprianto R; Fernandes VE; Andrew PW; van Strijp JA; Nijland R; Veening JW J Bacteriol 2014 ;0(0):0-0
pubmedlink 25512311

2014

To mutate or not to mutate: Genetic and epigenetic heterogeneity contribute to bacterial adaptation (comment on DOI 10.1002/bies.201400153). Veening JW Bioessays 2015 ;37(2):116-7
pubmedlink 25546613

2015

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Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall synthesis. Kjos M; Oppegard C; Diep DB; Nes IF; Veening JW; Nissen-Meyer J; Kristensen T Mol Microbiol 2014 ;92(6):1177-87
pubmedlink 24779486

2014

What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems. Bhogale PM; Sorg RA; Veening JW; Berg J Nucleic Acids Res 2015 ;42(18):11321-8
pubmedlink 25245949

2015

Lactic Acid Bacteria: embarking on 30 more years of research. Kok J; Johansen E; Kleerebezem M; Teusink B Microb Cell Fact 2014 ;13(0):0-0
pubmedlink 25187380

2014

Enterococcus faecalis zinc responsive proteins mediate bacterial defense against zinc overload, lysozyme and oxidative stress. Abrantes MC; Kok J; Lopes MD Microbiology 2014 ;0(0):0-0
pubmedlink 25312746

2014

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Physiological and cell morphology adaptation of Bacillus subtilis at near-zero specific growth rates: a transcriptome analysis. Overkamp W; Ercan O; Herber M; van Maris AJ; Kleerebezem M; Kuipers OP Environ Microbiol 2014 ;0(0):0-0
pubmedlink 25367190

2014

UlaR activates the expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid. Afzal M; Shafeeq S; Henriques-Normark B; Kuipers OP Microbiology 2014 ;0(0):0-0
pubmedlink 25355938

2014

Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae. Yuzenkova Y; Gamba P; Herber M; Attaiech L; Shafeeq S; Kuipers OP; Klumpp S; Zenkin N; Veening JW Nucleic Acids Res 2014 ;42(17):10987-99
pubmedlink 25190458

2014

The HtrA-like protease CD3284 modulates virulence of Clostridium difficile. Bakker D; Buckley AM; de Jong A; van Winden VJ; Verhoeks JP; Kuipers OP; Douce GR; Kuijper EJ; Smits WK; Corver J Infect Immun 2014 ;82(10):4222-32
pubmedlink 25047848

2014

Bacillus subtilis attachment to Aspergillus niger hyphae results in mutually altered metabolism. Benoit I; van den Esker MH; Patyshakuliyeva A; Mattern DJ; Blei F; Zhou M; Dijksterhuis J; Brakhage AA; Kuipers OP; de Vries RP; Kovacs AT Environ Microbiol 2014 ;0(0):0-0
pubmedlink 25040940

2014

Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin. Slager J; Kjos M; Attaiech L; Veening JW Cell 2014 ;157(2):395-406
pubmedlink 24725406

2014

The role of zinc in the interplay between pathogenic streptococci and their hosts. Shafeeq S; Kuipers OP; Kloosterman TG Mol Microbiol 2013 ;88(6):1047-57
pubmedlink 23650945

2013

Gene Expression Platform for Synthetic Biology in the Human Pathogen Streptococcus pneumoniae. Sorg RA; Kuipers OP; Veening JW ACS Synth Biol 2014 ;0(0):0-0
pubmedlink 24845455

2014

Control of the Diadenylate Cyclase CdaS in Bacillus subtilis: An Autoinhibitory Domain Limits c-di-AMP Production. Mehne FM; Schroder-Tittmann K; Eijlander RT; Herzberg C; Hewitt L; Kaever V; Lewis RJ; Kuipers OP; Tittmann K; Stulke J J Biol Chem 2014 ;0(0):0-0
pubmedlink 24939848

2014

RSV Increases the Virulence of Streptococcus pneumoniae by Binding to PBP1a: a New Paradigm in Respiratory Infection. Smith CM; Sandrini S; Datta S; Freestone P; Shafeeq S; Radhakrishnan P; Williams G; Glenn SM; Kuipers OP; Hirst RA; Easton AJ; Andrew PW; O Am J Respir Crit Care Med 2014 ;0(0):0-0
pubmedlink 24941423

2014

LacR is a repressor of lacABCD and LacT an activator of lacTFEG, constituting the lac-gene cluster in Streptococcus pneumoniae. Afzal M; Shafeeq S; Kuipers OP Appl Environ Microbiol 2014 ;0(0):0-0
pubmedlink 24951784

2014

Bet-hedging during bacterial diauxic shift. Solopova A; van Gestel J; Weissing FJ; Bachmann H; Teusink B; Kok J; Kuipers OP Proc Natl Acad Sci U S A 2014 ;0(0):0-0
pubmedlink 24799698

2014

Density of founder cells affects spatial pattern formation and cooperation in Bacillus subtilis biofilms. van Gestel J; Weissing FJ; Kuipers OP; Kovacs AT ISME J 2014 ;0(0):0-0
pubmedlink 24694715

2014

Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for cell shape maintenance. Peters K; Schweizer I; Beilharz K; Stahlmann C; Veening JW; Hakenbeck R; Denapaite D Mol Microbiol 2014 ;0(0):0-0
pubmedlink 24655324

2014

Exploiting the peptidoglycan-binding motif, LysM, for medical and industrial applications. Visweswaran GR; Leenhouts K; van Roosmalen M; Kok J; Buist G Appl Microbiol Biotechnol 2014 ;0(0):0-0
pubmedlink 24652063

2014

In Bacillus subtilis LutR is part of the global complex regulatory network governing the adaptation to the transition from exponential growth to stationary phase. Irigul-Sonmez O; Koroglu TE; Ozturk B; Kovacs AT; Kuipers OP; Yazgan-Karatas A Microbiology 2014 ;160(0):243-60
pdf for mg0797 pubmedlink 24196425

2014

Tracking of chromosome dynamics in live Streptococcus pneumoniae reveals that transcription promotes chromosome segregation. Kjos M; Veening JW Mol Microbiol 2014 ;0(0):0-0
pubmedlink 24417389

2014

Interlinked Sister Chromosomes Arise in the Absence of Condensin during Fast Replication in B. subtilis. Gruber S; Veening JW; Bach J; Blettinger M; Bramkamp M; Errington J Curr Biol 2014 ;24(3):293-8
pdf for mg0795 pubmedlink 24440399

2014

The YmdB Phosphodiesterase Is a Global Regulator of Late Adaptive Responses in Bacillus subtilis. Diethmaier C; Newman JA; Kovacs AT; Kaever V; Herzberg C; Rodrigues C; Boonstra M; Kuipers OP; Lewis RJ; Stulke J J Bacteriol 2014 ;196(2):265-75
pdf for mg0793 pubmedlink 24163345

2014

SporeWeb: an interactive journey through the complete sporulation cycle of Bacillus subtilis. Eijlander RT; de Jong A; Krawczyk AO; Holsappel S; Kuipers OP Nucleic Acids Res 2014 ;42(1):0-91
pdf for mg0792 pubmedlink 24170806

2014

Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies. Claessen D; Rozen DE; Kuipers OP; Sogaard-Andersen L; van Wezel GP Nat Rev Microbiol 2014 ;12(2):115-124
pdf for mg0790 pubmedlink 24384602

2014

Lactococcus lactis YfiA is necessary and sufficient for ribosome dimerisation. Puri P; Eckhardt TH; Franken LE; Fusetti F; Stuart MC; Boekema EJ; Kuipers OP; Kok J; Poolman B Mol Microbiol 2014 ;91(2):394-407
pubmedlink 24279750

2014

Comparative genomics and transcriptomics analysis of experimentally evolved Escherichia coli MC1000 in complex environments. Puentes-Tellez PE; Kovacs AT; Kuipers OP; van Elsas JD Environ Microbiol 2013 ;16(3):856-870
pubmedlink 24033913

2013

The Presence of Modifiable Residues in the Core Peptide Part of Precursor Nisin Is Not Crucial for Precursor Nisin Interactions with Khusainov R; Kuipers OP PLoS One 2013 ;8(9):0-0
pubmedlink 24040355

2013

How to get (a)round: mechanisms controlling growth and division of coccoid bacteria. Pinho MG; Kjos M; Veening JW Nat Rev Microbiol 2013 ;11(9):601-14
pubmedlink 23949602

2013

AcmD, a Homolog of the Major Autolysin AcmA of Lactococcus lactis, Binds to the Cell Wall and Contributes to Cell Separation and Autolysis. Visweswaran GR; Steen A; Leenhouts K; Szeliga M; Ruban B; Hesseling-Meinders A; Dijkstra BW; Kuipers OP; Kok J; Buist G PLoS One 2013 ;8(8):0-0
pubmedlink 23951292

2013

Benchmarking various GFP variants in Bacillus subtilis, Streptococcus pneumoniae and Lactococcus lactis for live cell imaging. Overkamp W; Beilharz K; Detert Oude Weme R; Solopova A; Karsens H; Kovacs AT; Kok J; Kuipers OP; Veening JW Appl Environ Microbiol 2013 ;79(20):6481-6490
pubmedlink 23956387

2013

Repeated triggering of sporulation in Bacillus subtilis selects against a protein that affects the timing of cell division. Siebring J; Elema MJ; Drubi Vega F; Kovacs AT; Haccou P; Kuipers OP ISME J 2013 ;8(1):77-87
pubmedlink 23924781

2013

Live cell imaging tool optimization to study gene expression levels and dynamics in single cells of Bacillus cereus. Eijlander RT; Kuipers OP Appl Environ Microbiol 2013 ;79(18):5643-5651
pubmedlink 23851094

2013

NisC Binds the FxLx Motif of the Nisin Leader Peptide. Abts A; Montalban-Lopez M; Kuipers OP; Smits SH; Schmitt L Biochemistry 2013 ;52(32):5387-5395
pubmedlink 23869662

2013

The localization of key Bacillus subtilis penicillin binding proteins during cell growth is determined by substrate availability. Lages MC; Beilharz K; Morales Angeles D; Veening JW; Scheffers DJ Environ Microbiol 2013 ;15(12):3272-3281
pubmedlink 23895585

2013

Pyruvate Oxidase Influences the Sugar Utilization Pattern and Capsule Production in Streptococcus pneumoniae. Carvalho SM; Farshchi Andisi V; Gradstedt H; Neef J; Kuipers OP; Neves AR; Bijlsma JJ PLoS One 2013 ;8(7):0-0
pubmedlink 23844180

2013

Metabolic and Transcriptional Analysis of Acid Stress in Lactococcus lactis, with a Focus on the Kinetics of Lactic Acid Pools. Carvalho AL; Turner DL; Fonseca LL; Solopova A; Catarino T; Kuipers OP; Voit EO; Neves AR; Santos H PLoS One 2013 ;8(7):0-0
pubmedlink 23844205

2013

BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides. van Heel AJ; de Jong A; Montalban-Lopez M; Kok J; Kuipers OP Nucleic Acids Res 2013 ;41(0):0-53
pubmedlink 23677608

2013

Identification of distinct nisin leader peptide regions that determine interactions with the modification enzymes NisB and NisC. Khusainov R; Moll GN; Kuipers OP FEBS Open Bio 2013 ;3(0):237-42
pubmedlink 23772400

2013

A single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase renders Streptococcus pneumoniae dependent on CO and temperature. Burghout P; Quintero B; Bos L; Beilharz K; Veening JW; de Jonge MI; van der Linden M; van der Ende A; Hermans PW Mol Microbiol 2013 ;89(3):494-506
pubmedlink 23750975

2013

Functional analysis of the ComK protein of Bacillus coagulans. Kovacs AT; Eckhardt TH; van Hartskamp M; van Kranenburg R; Kuipers OP PLoS One 2013 ;8(1):0-0
pubmedlink 23301076

2013

Designing and Producing Modified, New-to-Nature Peptides with Antimicrobial Activity by Use of a Combination of Various Lantibiotic Modification Enzymes. van Heel AJ; Mu D; Montalban-Lopez M; Hendriks D; Kuipers OP ACS Synth Biol 2013 ;79(14):4503-4508
pubmedlink 23654279

2013

Zirex: a novel Zinc-regulated expression system for Lactococcus lactis. Mu D; Montalban-Lopez M; Masuda Y; Kuipers OP Appl Environ Microbiol 2013 ;79(14):4503-8
pubmedlink 23666339

2013

Balanced transcription of cell division genes in Bacillus subtilis as revealed by single cell analysis. Trip EN; Veening JW; Stewart EJ; Errington J; Scheffers DJ Environ Microbiol 2013 ;15(12):3196-3209
pubmedlink 23701187

2013

Regulation of arginine acquisition and virulence gene expression in the human pathogen Streptococcus pneumoniae by transcription regulators ArgR1 and AhrC. Kloosterman TG; Kuipers OP J Biol Chem 2013 ;288(15):10950-0
pubmedlink 23585656

2013

Environmental and nutritional factors that affect growth and metabolism of the pneumococcal serotype 2 strain d39 and its nonencapsulated derivative strain r6. Carvalho SM; Kuipers OP; Neves AR PLoS One 2013 ;8(3):0-0
pubmedlink 23505518

2013

Cellobiose-Mediated Gene Expression in Streptococcus pneumoniae: A Repressor Function of the Novel GntR-Type Regulator BguR. Shafeeq S; Kuipers OP; Kloosterman TG PLoS One 2013 ;8(2):0-0
pubmedlink 23469031

2013

The Transcriptional and Gene Regulatory Network of Lactococcus lactis MG1363 during Growth in Milk. de Jong A; Hansen ME; Kuipers OP; Kilstrup M; Kok J PLoS One 2013 ;8(1):0-0
pubmedlink 23349698

2013

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Arnison PG; Bibb MJ; Bierbaum G; Bowers AA; Bugni TS; Bulaj G; Camarero JA; Campopiano DJ; Challis GL; Clardy J; Cotter PD; Craik DJ; Dawson M; Dittmann E; Donadio S; Dorrestein PC; Entian KD; Fischbach MA; Garavelli JS; Goransson U; Gruber CW; Haft DH; Hemscheidt TK; Hertweck C; Hill C; Horswill AR; Jaspars M; Kelly WL; Klinman JP; Kuipers OP; Link AJ; Liu W; Marahiel MA; Mitchell DA; Moll GN; Moore BS; Muller R; Nair SK; Nes IF; Norris GE; Olivera BM; Onaka H; Patchett ML; Piel J; Reaney MJ; Rebuffat S; Ross RP; Sahl HG; Schmidt EW; Selsted ME; Severinov K; Shen B; Sivonen K; Smith L; Stein T; Sussmuth RD; Tagg JR; Tang GL; Truman AW; Vederas JC; Walsh CT; Walton JD; Wenzel SC; Willey JM; van der Donk WA Nat Prod Rep 2012 ;30(1):108-60
pubmedlink 23165928

2012

The DEAD-box RNA helicases in Bacillus subtilis have multiple functions and act independent from each other. Lehnik-Habrink M; Rempeters L; Kovacs AT; Wrede C; Baierlein C; Krebber H; Kuipers OP; Stulke J J Bacteriol 2012 ;0(0):0-0
pubmedlink 23175651

2012

Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily. Fibriansah G; Kovacs AT; Pool TJ; Boonstra M; Kuipers OP; Thunnissen AM PLoS One 2012 ;7(11):0-0
pubmedlink 23189126

2012

EfaR is a major regulator of Enterococcus faecalis manganese transporters and influences processes involved in host colonization and infection. Abrantes MC; Kok J; Lopes MD Infect Immun 2013 ;81(3):935-44
pubmedlink 23297382

2013

Transcriptional regulation of fatty acid biosynthesis in Lactococcus lactis. Eckhardt TH; Skotnicka D; Kok J; Kuipers OP J Bacteriol 2012 ;0(0):0-0
pubmedlink 23275247

2012

Perspectives on the contribution of lactic acid bacteria to cheese flavor development. Steele J; Broadbent J; Kok J Curr Opin Biotechnol 2012 ;0(0):0-0
pubmedlink 23279928

2012

Spo0A regulates chromosome copy number during sporulation by directly binding to the origin of replication in Bacillus subtilis. Boonstra M; de Jong IG; Scholefield G; Murray H; Kuipers OP; Veening JW Mol Microbiol 2013 ;87(4):925-938
pubmedlink 23301687

2013

From meadows to milk to mucosa - adaptation of Streptococcus and Lactococcus species to their nutritional environment Price CE; Zeyniyev A; Kuipers OP; Kok J FEMS Microbiol Rev 2011 ;0(0):0-0
pubmedlink 22212109

2011

High- and low-affinity cre boxes for CcpA bindin in Bacillus Subtilus revealed by genome-wide analysis Marciniak BC; Pabijaniak M; de Jong A; Duhring R; Seidel G; Hillen W; Kuipers OP BMC Genomics 2012 ;13(0):401-0
pubmedlink 22900538

2012

CodY, a pleiotropic regulator, influences multicellular behaviour and efficient production of virulence factors in Bacillus cereus. Lindback T; Mols M; Basset C; Granum PE; Kuipers OP; Kovacs AT Environ Microbiol 2012 ;14(8):2233-46
pubmedlink 22540344

2012

Characterization of the ROK-family transcriptional regulator RokA of Streptococcus pneumoniae D39. Shafeeq S; Kloosterman TG; Rajendran V; Kuipers OP Microbiology 2012 ;0(0):0-0
pubmedlink 23082033

2012

When the Leader Gets Loose: In Vivo Biosynthesis of a Leaderless Prenisin Is Stimulated by a trans-Acting Leader Peptide. Khusainov R; Kuipers OP Chembiochem 2012 ;0(0):0-0
pubmedlink 23070977

2012

Single cell analysis of gene expression patterns during carbon starvation in Bacillus subtilis reveals large phenotypic variation. de Jong IG; Veening JW; Kuipers OP Environ Microbiol 2012 ;0(0):0-0
pubmedlink 23033921

2012

Iron starvation triggers the stringent response and induces amino acid biosynthesis for bacillibactin production in Bacillus subtilis. Miethke M; Westers H; Blom EJ; Kuipers OP; Marahiel MA J Bacteriol 2006 ;188(24):8655-7
pubmedlink 17012385

2006

9th International Symposium on Lactic Acid Bacteria. Kuipers OP; Poolman B; Hugenholtz J Appl Environ Microbiol 2008 ;74(15):4589-0
pubmedlink 18586976

2008

The putative lactococcal extracytoplasmic function (ECF) anti-sigma factor Llmg2447 determines resistance to the cell wall-active bacteriocin Lcn972. Roces C; Perez V; Campelo AB; Blanco D; Kok J; Kuipers OP; Rodriguez A; Martinez B Antimicrob Agents Chemother 2012 ;0(0):0-0
pubmedlink 22890757

2012

PePPER: a webserver for prediction of prokaryote promoter elements and regulons. de Jong A; Pietersma H; Cordes M; Kuipers OP; Kok J BMC Genomics 2012 ;13(1):299-0
pubmedlink 22747501

2012

Increasing the success rate of lantibiotic drug discovery by Synthetic Biology. Montalban-Lopez M; Zhou L; Buivydas A; van Heel AJ; Kuipers OP Expert Opin Drug Discov 2012 ;0(0):0-0
pubmedlink 22680308

2012

Comparative transcriptional analysis of bacillus subtilis cells overproducing either secreted proteins, lipoproteins or membrane proteins. Marciniak BC; Trip H; van-der Veek PJ; Kuipers OP Microb Cell Fact 2012 ;11(1):66-0
pubmedlink 22624725

2012

A specific mutation in the promoter region of the silent cel cluster accounts for the appearance of lactose-utilizing Lactococcus lactis MG1363. Solopova A; Bachmann H; Teusink B; Kok J; Neves AR; Kuipers OP Appl Environ Microbiol 2012 ;0(0):0-0
pubmedlink 22660716

2012

The protective layer of biofilm: a repellent function for a new class of amphiphilic proteins. Kovacs AT; van Gestel J; Kuipers OP Mol Microbiol 2012 ;0(0):0-0
pubmedlink 22607588

2012

Purification and characterization of two phospho-beta-galactosidases, LacG1 and LacG2, from Lactobacillus gasseri ATCC33323(T). Honda H; Nagaoka S; Kawai Y; Kemperman R; Kok J; Yamazaki Y; Tateno Y; Kitazawa H; Saito T J Gen Appl Microbiol 2012 ;58(1):11-7
pubmedlink 22449746

2012

Regulation of ykrL (htpX) by Rok and YkrK, a novel type of regulator in Bacillus subtilis. Marciniak BC; Trip H; Fusetti F; Kuipers OP J Bacteriol 2012 ;194(11):2837-2845
pubmedlink 22447908

2012

Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP. Beilharz K; Novakova L; Fadda D; Branny P; Massidda O; Veening JW Proc Natl Acad Sci U S A 2012 ;0(0):0-0
pubmedlink 22431591

2012

CcpA ensures optimal metabolic fitness of Streptococcus pneumoniae. Carvalho SM; Kloosterman TG; Kuipers OP; Neves AR PLoS One 2011 ;6(10):0-0
pubmedlink 22039538

2011

Time-resolved transcriptomics and bioinformatic analyses reveal intrinsic stress responses during batch culture of Bacillus subtilis. Blom EJ; Ridder AN; Lulko AT; Roerdink JB; Kuipers OP PLoS One 2011 ;6(11):0-0
pubmedlink 22087258

2011

Culture heterogeneity in zeta potential is linked to Ebp in Enterococcus faecalis. Tariq M; Bruijs C; Kok J; Krom BP Appl Environ Microbiol 2012 ;78(7):2282-2288
pubmedlink 22267669

2012

Regulation of Arginine Acquisition and Virulence Gene Expression in the Human Pathogen Streptococcus pneumoniae by Transcription Regulators ArgR1 and AhrC. Kloosterman TG; Kuipers OP J Biol Chem 2011 ;286(52):44594-605
pubmedlink 22084243

2011

A genetically engineered protein domain binding to bacterial murein, archaeal pseudomurein, and fungal chitin cell wall material. Visweswaran GR; Dijkstra BW; Kok J Appl Microbiol Biotechnol 2012 ;0(0):0-0
pubmedlink 22262228

2012

A Pneumococcal Gene Complex Involved in Resistance to Extracellular Oxidative Stress. Farshchi Andisi V; Hinojosa CA; de Jong A; Kuipers OP; Orihuela CJ; Bijlsma JJ Infect Immun 2012 ;80(3):1037-1049
pubmedlink 22215735

2012

Large-Scale Screening of a Targeted Enterococcus faecalis Mutant Library Identifies Envelope Fitness Factors. Rigottier-Gois L; Alberti A; Houel A; Taly JF; Palcy P; Manson J; Pinto D; Matos RC; Carrilero L; Montero N; Tariq M; Karsens H; Repp C; Kropec A; Budin-Verneuil A; Benachour A; Sauvageot N; Bizzini A; Gilmore MS; Bessieres P; Kok J; Huebner J; Lopes F; Gonzalez-Zorn B; Hartke A; Serror P PLoS One 2011 ;6(12):0-0
pubmedlink 22194979

2011

Heterologous Protein Expression by Lactococcus lactis. Villatoro-Hernandez J; Kuipers OP; Saucedo-Cardenas O; Montes-de-Oca-Luna R Methods Mol Biol 2012 ;824(0):155-65
pubmedlink 22160898

2012

Bacillus cereus responses to acid stress. Mols M; Abee T Environ Microbiol 2011 ;13(11):2835-43
pubmedlink 21554514

2011

Future Challenges in Lactic Acid Bacteria Stress Physiology Research (chapter 21) Papadimitriou K, Kok, J. Book: Sress Responses of lactic Acid Bacteria ISBN 978-0-387-91771-8 2011 ;0(0):507-518

2011

Responses of Lactic Acid Bacteria to Cell Envelope Stresses (chapter 8) Pinto J.P.C., Kuipers O.P., Kok J. Book: Stress Responses of Lactic Bacteria ISBN 978-0-387-92770-1 2011 ;0(0):145-161

2011

Transcriptional responses of Bacillus cereus towards challenges with the polysaccharide chitosan. Mellegard H; Kovacs AT; Lindback T; Christensen BE; Kuipers OP; Granum PE PLoS One 2011 ;6(9):0-0
pubmedlink 21931677

2011

Determining sites of interaction between prenisin and its modification enzymes NisB and NisC. Khusainov R; Heils R; Lubelski J; Moll GN; Kuipers OP Mol Microbiol 2011 ;82(3):706-18
pubmedlink 22011325

2011

The proceedings of the Tenth Symposium on Lactic Acid Bacteria. Hill C; Kleerebezem M; Kok J Microb Cell Fact 2011 ;10(0):0-0
pubmedlink 21995427

2011

Impact of Manganese, Copper and Zinc Ions on the Transcriptome of the Nosocomial Pathogen Enterococcus faecalis V583. Coelho Abrantes M; Lopes Mde F; Kok J PLoS One 2011 ;6(10):0-0
pubmedlink 22053193

2011

Murein and pseudomurein cell wall binding domains of bacteria and archaea-a comparative view. Visweswaran GR; Dijkstra BW; Kok J Appl Microbiol Biotechnol 2011 ;0(0):0-0
pubmedlink 22012341

2011

The Response of Lactococcus lactis to Membrane Protein Production. Marreddy RK; Pinto JP; Wolters JC; Geertsma ER; Fusetti F; Permentier HP; Kuipers OP; Kok J; Poolman B PLoS One 2011 ;6(8):0-0
pubmedlink 21904605

2011

The Lcn972-bacteriocin plasmid pBL1 impairs cellobiose metabolism in Lactococcus lactis. Campelo AB; Gaspar P; Roces C; Rodriguez A; Kok J; Kuipers OP; Neves AR; Martinez B Appl Environ Microbiol 2011 ;77(21):7576-7585
pubmedlink 21890668

2011

The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae. Shafeeq S; Yesilkaya H; Kloosterman TG; Narayanan G; Andrew PW; Kuipers OP; Morrissey JA Mol Microbiol 2011 ;0(0):0-0
pubmedlink 21736642

2011

pSEUDO, a genetic integration standard for Lactococcus lactis. Pinto JP; Zeyniyev A; Karsens H; Trip H; Lolkema JS; Kuipers OP; Kok J Appl Environ Microbiol 2011 ;77(18):6687-6690
pdf for mg0660 pubmedlink 21764949

2011

CelR-mediated activation of the cellobiose-uptake gene cluster in Streptococcus pneumoniae. Shafeeq S; Kloosterman TG; Kuipers OP Microbiology 2011 ;0(0):0-0
pubmedlink 21778207

2011

Efficient Overproduction of Membrane Proteins in Lactococcus lactis Requires the Cell Envelope Stress Sensor/Regulator Couple CesSR. Pinto JP; Kuipers OP; Marreddy RK; Poolman B; Kok J PLoS One 2011 ;6(7):0-0
pdf for mg0658 pubmedlink 21818275

2011

Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. de Jong IG; Beilharz K; Kuipers OP; Veening JW J Vis Exp 2011 ;0(53):0-0
pubmedlink 21841760

2011

A Minimum of Three Motifs Is Essential for Optimal Binding of Pseudomurein Cell Wall-Binding Domain of Methanothermobacter thermautotrophicus. Visweswaran GR; Dijkstra BW; Kok J PLoS One 2011 ;6(6):0-0
pdf for mg0656 pubmedlink 21738718

2011

Distinct Roles of ComK1 and ComK2 in Gene Regulation in Bacillus cereus. Mironczuk AM; Manu A; Kuipers OP; Kovacs AT PLoS One 2011 ;6(7):0-0
pdf for mg0655 pubmedlink 21747963

2011

A novel screening system for secretion of heterologous proteins in Bacillus subtilis. Trip H; van der Veek PJ; Renniers TC; Meima R; Sagt CM; Mohrmann L; Kuipers OP Microb Biotechnol 2011 ;0(0):0-0
pubmedlink 21624103

2011

SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae. Minnen A; Attaiech L; Thon M; Gruber S; Veening JW Mol Microbiol 2011 ;0(0):0-0
pdf for mg0653 pubmedlink 21651626

2011

The regulon of the N-Acetylglucosamine utilization regulator (NagR) in Bacillus subtilis. Bertram R; Rigali S; Wood N; Lulko AT; Kuipers OP; Titgemeyer F J Bacteriol 2011 ;198(14):609-618
pdf for mg0651 pubmedlink 21602348

2011

Transcriptional response of Streptococcus pneumoniae to Zn(2+) limitation and the repressor/activator function of AdcR. Shafeeq S; Kloosterman TG; Kuipers OP Metallomics 2011 ;3(6):609-618
pubmedlink 21603707

2011

Genome Exploitation and Bioinformatics Tools de Jong A; van Heel AJ; Kuipers OP Prokaryotic Antimicrobial Peptides: From Genes to Applications 2011 ;0(0):0-0
pdf for mg0647

2011

Evaluating the feasibility of lantibiotics as an alternative therapy against bacterial infections in humans. van Heel AJ; Montalban-Lopez M; Kuipers OP Expert Opin Drug Metab Toxicol 2011 ;6(0):675-680
pdf for mg0646 pubmedlink 21521092

2011

Data resources and mining tools for reconstructing gene regulatory networks in Lactococcus lactis de Jong A; Kok J; Kuipers OP Japanese Journal of Lactic Acid Bacteria 2011 ;22(1):1-14
pdf for mg0645

2011

Potential antibiotic and anti-infective effects of rhodomyrtone from Rhodomyrtus tomentosa (Aiton) Hassk. on Streptococcus pyogenes as revealed by proteomics. Limsuwan S; Hesseling-Meinders A; Voravuthikunchai SP; van Dijl JM; Kayser O Phytomedicine 2011 ;0(0):0-0
pubmedlink 21439802

2011

Deletion of a cation transporter promotes lysis in Streptococcus pneumoniae. Neef J; Farshchi Andisi V; Kim KS; Kuipers OP; Bijlsma JJ Infect Immun 2011 ;79(0):2314-2323
pdf for mg0643 pubmedlink 21422174

2011

Understanding microbial behavior within and outside the host to improve food functionality and safety. Abee T; Kuipers OP Curr Opin Biotechnol 2011 ;22(0):133-135
pdf for mg0642 pubmedlink 21334191

2011

Bet hedging or not? A guide to proper classification of microbial survival strategies. de Jong IG; Haccou P; Kuipers OP Bioessays 2011 ;33(3):215-223
pdf for mg0641 pubmedlink 21254151

2011

Bacterial spores in food: how phenotypic variability complicates prediction of spore properties and bacterial behavior. Eijlander RT; Abee T; Kuipers OP Curr Opin Biotechnol 2011 ;22(0):180-186
pdf for mg0640 pubmedlink 21134736

2011

Targeting diseases with genetically engineered Lactococcus lactis and its course towards medical translation. Villatoro-Hernandez J; Montes-de-Oca-Luna R; Kuipers OP Expert Opin Biol Ther 2011 ;11(3):261-267
pdf for mg0639 pubmedlink 21204744

2011

Gene cluster for biosynthesis of thermophilin 1 Kabuki T; Kawai Y; Uenishi H; Seto Y; Kok J; Nakajima H; Saito T J Appl Microbiol 2011 ;110(3):641-649
pdf for mg0638 pubmedlink 21182576

2011

Two Major Archaeal Pseudomurein Endoisopeptidases: PeiW and PeiP. Visweswaran GR; Dijkstra BW; Kok J Archaea 2010 ;2010(0):480492-0
pdf for mg0637 pubmedlink 21113291

2010

Biofilm formation and dispersal in Gram-positive bacteria. Abee T; Kovacs AT; Kuipers OP; van der Veen S Curr Opin Biotechnol 2011 ;22(0):172-179
pdf for mg0635 pubmedlink 21109420

2011

DnaA and ORC: more than DNA replication initiators. Scholefield G; Veening JW; Murray H Trends Cell Biol 2011 ;21(3):188-194
pdf for mg0634 pubmedlink 21123069

2011

Rok regulates yuaB expression during architecturally complex colony development of Bacillus subtilis 168. Kovacs AT; Kuipers OP J Bacteriol 2011 ;193(0):998-1002
pdf for mg0631 pubmedlink 21097620

2011

SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks. Westenberg MA; Roerdink JB; Kuipers OP; van Hijum SA Bioinformatics 2010 ;26(22):2922-2923
pdf for mg0629 pubmedlink 20861033

2010

Towards enhanced galactose utilization by Lactococcus lactis. Neves AR; Pool WA; Solopova A; Kok J; Santos H; Kuipers OP Appl Environ Microbiol 2010 ;76(21):7048-7060
pdf for mg0628 pubmedlink 20817811

2010

How mathematical modelling elucidates signalling in B. subtilis. Liebal UW; Millat T; de Jong IG; Kuipers OP; Volker U; Wolkenhauer O 2010 ;77(5):1083-1095
pdf for mg0627 pubmedlink 20624218

2010

Genome sequences of Lactococcus lactis MG1363 (revised) and NZ9000 and comparative physiological studies. Linares DM; Kok J; Poolman B J Bacteriol 2010 ;192(21):5806-5812
pdf for mg0626 pubmedlink 20639323

2010

Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus subtilis. Hyyrylainen HL; Marciniak BC; Dahncke K; Pietiainen M; Courtin P; Vitikainen M; Seppala R; Otto A; Becher D; Chapot-Chartier MP; Kuipers OP; Kontinen VP Mol Microbiol 2010 ;77(1):108-127
pdf for mg0625 pubmedlink 20487272

2010

BAGEL2: mining for bacteriocins in genomic data. de Jong A; van Heel AJ; Kok J; Kuipers OP Nucleic Acids Res 2010 ;0(0):1-5
pdf for mg0621 pubmedlink 20462861

2010

Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. Marreddy RK; Geertsma ER; Permentier HP; Pinto JP; Kok J; Poolman B PLoS One 2010 ;5(4):0-0
pdf for mg0619 pubmedlink 20436673

2010

Introducing a new host for biotechnology: Genetic tool development for the thermotolerant Bacillus coagulans. Kovacs AT; van Hartskamp M; Kuipers OP; van Kranenburg R Appl Environ Microbiol 2010 ;11(0):1911-1922
pdf for mg0618 pubmedlink 20400555

2010

sigma54-Mediated control of the mannose phosphotransferase sytem in Lactobacillus plantarum impacts on carbohydrate metabolism. Stevens MJ; Molenaar D; de Jong A; De Vos WM; Kleerebezem M Microbiology 2010 ;156(0):695-707
pdf for mg0617 pubmedlink 19942662

2010

Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation. de Jong IG; Veening JW; Kuipers OP J Bacteriol 2010 ;192(8):2053-2067
pdf for mg0616 pubmedlink 20154131

2010

Gene position within a long transcript as a determinant for stochastic switching in bacteria. Veening JW; Kuipers OP Mol Microbiol 2010 ;76(2):269-272
pdf for mg0615 pubmedlink 20233302

2010

Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. Chillappagari S; Seubert A; Trip H; Kuipers OP; Marahiel MA; Miethke M J Bacteriol 2010 ;192(10):2512-2524
pdf for mg0614 pubmedlink 20233928

2010

Transformation of environmental bacillus subtilis isolates by transiently inducing genetic competence. Nijland R; Burgess JG; Errington J; Veening JW PLoS One 2010 ;5(3):0-0
pdf for mg0613 pubmedlink 20300532

2010

Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence. Majchrzykiewicz JA; Lubelski J; Moll GN; Kuipers A; Bijlsma JJ; Kuipers OP; Rink R Antimicrob Agents Chemother 2010 ;54(0):1498-505
pdf for mg0612 pubmedlink 20100873

2010

Generic and specific adaptive responses of Streptococcus pneumoniae to challenge with three distinct antimicrobial peptides, bacitracin, LL-37, and nisin. Majchrzykiewicz JA; Kuipers OP; Bijlsma JJ Antimicrob Agents Chemother 2010 ;54(1):440-51
pdf for mg0611 pubmedlink 19917758

2010

Adaptation of Hansenula polymorpha to methanol: a transcriptome analysis. van Zutphen T; Baerends RJ; Susanna KA; de Jong A; Kuipers OP; Veenhuis M; van der Klei IJ BMC Genomics 2010 ;11(1):1-0
pdf for mg0610 pubmedlink 20044946

2010

Transcriptome and proteome analysis of ovaries of arrhenotokous and thelytokous Venturia canescens. Mateo Leach I; Hesseling A; Huibers WH; Witsenboer H; Beukeboom LW; van de Zande L Insect Mol Biol 2009 ;18(4):477-82
pdf for mg0608 pubmedlink 19453764

2009

Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48. Grande Burgos MJ; Kovacs AT; Mironczuk AM; Abriouel H; Galvez A; Kuipers OP BMC Microbiol 2009 ;0(0):0-0
pubmedlink 19863785

2009

Induction of natural competence in Bacillus cereus ATCC14579 Mironczuk AM; Kovacs AT; Kuipers OP Microbial Biotechnology 2008 ;1(3):226-235
pdf for mg0606

2008

Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin. Lubelski J; Khusainov R; Kuipers OP J Biol Chem 2009 ;284(38):25962-72
pdf for mg0605 pubmedlink 19620240

2009

Cellular localization of choline-utilization proteins in Streptococcus pneumoniae using novel fluorescent reporter systems. Eberhardt A; Wu LJ; Errington J; Vollmer W; Veening JW Mol Microbiol 2009 ;74(2):395-408
pdf for mg0604 pubmedlink 19737355

2009

Ubiquitous late competence genes in Bacillus species indicate the presence of functional DNA uptake machineries. Kovacs AT; Smits WK; Mironczuk AM; Kuipers OP Environ Microbiol 2009 ;11(8):1911-22
pdf for mg0602 pubmedlink 19453701

2009

Mechanisms and evolution of control logic in prokaryotic transcriptional regulation. van Hijum SA; Medema MH; Kuipers OP Microbiol Mol Biol Rev 2009 ;73(3):481-509
pdf for mg0601 pubmedlink 19721087

2009

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence. Hendriksen WT; Bootsma HJ; van Diepen A; Estevao S; Kuipers OP; de Groot R; Hermans PW Microbiology 2009 ;155(0):1569-79
pdf for mg0600 pubmedlink 19372167

2009

Effects of altered TatC proteins on protein secretion efficiency via the twin-arginine translocation pathway of Bacillus subtilis. Eijlander RT; Kolbusz MA; Berendsen EM; Kuipers OP Microbiology 2009 ;155(0):1776-1785
pdf for mg0599 pubmedlink 19383693

2009

Subcellular localisation of TatAd of Bacillus subtilis depends on the presence of TatCd or TatCy. Ridder AN; de Jong EJ; Jongbloed JD; Kuipers OP J Bacteriol 2009 ;191(13):4410-4418
pdf for mg0598 pubmedlink 19395490

2009

Comparative analysis of cervical cancer patients (late stage survival) before and after medical treatment. In: Biomarker Discovery for Cervical Cancer. Methods and Approaches. Govorukhina, N.I;, Hesseling, A.;, Horvatovich, P.; de Vries, M.; Suits, A.; Bisschoff, R. 2008 ;0(0):153-178

2008

Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis. Chillappagari S; Miethke M; Trip H; Kuipers OP; Marahiel MA J Bacteriol 2009 ;191(7):2362-2370
pdf for mg0596 pubmedlink 19168619

2009

MOTIFATOR: detection and characterization of regulatory motifs using prokaryote transcriptome data. Blom EJ; Roerdink JB; Kuipers OP; van Hijum SA Bioinformatics 2009 ;25(4):550-551
pdf for mg0595 pubmedlink 19168910

2009

DNA Sequencing and Homologous Expression of a Small Peptide Conferring Immunity to Gassericin A, a Circular Bacteriocin Produced by Lactobacillus gasseri LA39. Kawai Y; Kusnadi J; Kemperman R; Kok J; Ito Y; Endo M; Arakawa K; Uchida H; Nishimura J; Kitazawa H; Saito T Appl Environ Microbiol 2009 ;75(0):1324-1330
pdf for mg0594 pubmedlink 19114506

2009

Optimization of protein secretion by Bacillus subtilis. Nijland R; Kuipers OP Recent Pat Biotechnol 2008 ;2(2):79-87
pubmedlink 19075856

2008

DISCLOSE : DISsection of CLusters Obtained by SEries of transcriptome data using functional annotations and putative transcription factor binding sites. Blom EJ; van Hijum SA; Hofstede KJ; Silvis R; Roerdink JB; Kuipers OP BMC Bioinformatics 2008 ;9(1):535-0
pdf for mg0592 pubmedlink 19087282

2008

Visualizing genome expression and regulatory network dynamics in genomic and metabolic context Westenberg MA; van Hijum SAFT; Kuipers OP; Roerdink JBTM Computer Graphics Forum 2008 ;27(3):887-894
pdf for mg0591

2008

Characterization of the individual glucose uptake systems of Lactococcus lactis: mannose-PTS, cellobiose-PTS and the novel GlcU permease. Castro R; Neves AR; Fonseca LL; Pool WA; Kok J; Kuipers OP; Santos H Mol Microbiol 2009 ;71(3):795-806
pdf for mg0588 pubmedlink 19054326

2009

The twin-arginine translocation (Tat) systems from Bacillus subtilis display a conserved mode of complex organization and similar substrate recognition requirements. Barnett JP; van der Ploeg R; Eijlander RT; Nenninger A; Mendel S; Rozeboom R; Kuipers OP; van Dijl JM; Robinson C FEBS J 2009 ;276(1):232-243
pdf for mg0587 pubmedlink 19049517

2009

MINOMICS: visualizing prokaryote transcriptomics and proteomics data in a genomic context. Brouwer RW; Hijum SA; Kuipers OP Bioinformatics 2009 ;25(1):139-140
pdf for mg0586 pubmedlink 19008250

2009

Supervised Lowess normalization of comparative genome hybridization data--application to lactococcal strain comparisons. van Hijum SA; Baerends RJ; Zomer AL; Karsens HA; Martin-Requena V; Trelles O; Kok J; Kuipers OP BMC Bioinformatics 2008 ;9(0):93-93
pdf for mg0585 pubmedlink 18267014

2008

Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context and multiple gene annotation sources. Blom EJ; Breitling R; Hofstede KJ; Roerdink JB; van Hijum SA; Kuipers OP BMC Genomics 2008 ;9(1):495-0
pdf for mg0584 pubmedlink 18939968

2008

Relaxed specificity of the Bacillus subtilis TatAdCd translocase in Tat-dependent protein secretion. Eijlander RT; Jongbloed JD; Kuipers OP J Bacteriol 2009 ;19(1):196-202
pdf for mg0583 pubmedlink 18978042

2009

The ABC-type MDR transporter LmrCD is responsible for an extrusion based mechanism of bile acid resistance in Lactococcus lactis. Zaidi AH; Bakkes PJ; Lubelski J; Agustiandari H; Kuipers OP; Driessen AJ J Bacteriol 2008 ;190(22):7357-66
pdf for mg0582 pubmedlink 18790870

2008

Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis. Kramer NE; Hasper HE; van den Bogaard PT; Morath S; de Kruijff B; Hartung T; Smid EJ; Breukink E; Kok J; Kuipers OP Microbiology 2008 ;154(0):1755-62
pdf for mg0581 pubmedlink 18524930

2008

Bistability, Epigenetics, and Bet-Hedging in Bacteria. Veening JW; Smits WK; Kuipers OP Annu Rev Microbiol 2008 ;62(0):193-210
pdf for mg0580 pubmedlink 18537474

2008

Transcriptome analysis of the ArgR and AhrC regulons in Lactococcus lactis. Larsen R; van Hijum SA; Martinussen J; Kuipers OP; Kok J Appl Environ Microbiol 2008 ;74(15):4768-4771
pdf for mg0579 pubmedlink 18539789

2008

Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the autolysin AcmA. Steen A; Buist G; Kramer NE; Jalving R; Benus GF; Venema G; Kuipers OP; Kok J Appl Environ Microbiol 2008 ;74(15):4671-4679
pdf for mg0578 pubmedlink 18539791

2008

The influence of shifting positions of Ser, Thr and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activity of the modified propeptides. Lubelski J; Overkamp W; Kluskens LD; Moll GN; Kuipers OP Appl Environ Microbiol 2008 ;74(15):4680-4685
pdf for mg0577 pubmedlink 18539792

2008

Improvement of Lactobacillus plantarum Aerobic Growth, Directed by Comprehensive Transcriptome Analysis. Stevens MJ; Wiersma A; De Vos WM; Kuipers OP; Smid EJ; Molenaar D; Kleerebezem M Appl Environ Microbiol 2008 ;74(15):4776-4778
pdf for mg0576 pubmedlink 18539801

2008

Opposite effects of Mn2+ and Zn2+ on the PsaR-mediated expression of the virulence genes pcpA, prtA and psaBCA of Streptococcus pneumoniae. Kloosterman T; Witwicki RM; van der Kooi-Pol MM; Bijlsma JJ; Kuipers OP J Bacteriol 2008 ;190(15):5382-5393
pdf for mg0575 pubmedlink 18515418

2008

Transient heterogeneity in extracellular protease production by Bacillus subtilis. Veening JW; Igoshin OA; Eijlander RT; Nijland R; Hamoen LW; Kuipers OP Mol Syst Biol 2008 ;4(0):184-0
pdf for mg0573 pubmedlink 18414485

2008

Assessment of CcpA-mediated catabolite control of gene expression in Bacillus cereus ATCC 14579. van der Voort M; Kuipers OP; Buist G; de Vos WM; Abee T BMC Microbiol 2008 ;8(1):62-0
pdf for mg0572 pubmedlink 18416820

2008

The relative value of operon predictions. Brouwer RW; Kuipers OP; Hijum SA Brief Bioinform 2008 ;9(5):367-375
pdf for mg0571 pubmedlink 18420711

2008

LysM, a widely distributed protein motif for binding to (peptido)glycans. Buist G; Steen A; Kok J; Kuipers OP Mol Microbiol 2008 ;68(4):838-47
pdf for mg0570 pubmedlink 18430080

2008

Bet-hedging and epigenetic inheritance in bacterial cell development. Veening JW; Stewart EJ; Berngruber TW; Taddei F; Kuipers OP; Hamoen LW Proc Natl Acad Sci U S A 2008 ;105(11):4393-4398
pdf for mg0569 pubmedlink 18326026

2008

Site-specific contributions of glutamine-dependent regulator GlnR and GlnR-regulated genes to virulence of Streptococcus pneumoniae. Hendriksen WT; Kloosterman TG; Bootsma HJ; Estevao S; de Groot R; Kuipers OP; Hermans PW Infect Immun 2008 ;76(3):1230-8
pdf for mg0567 pubmedlink 18174343

2008

A facile reporter system for the experimental identification of twin-arginine translocation (Tat) signal peptides from all kingdoms of life. Widdick DA; Eijlander RT; van Dijl JM; Kuipers OP; Palmer T J Mol Biol 2008 ;375(3):595-603
pdf for mg0566 pubmedlink 18054046

2008

The Escherichia coli TatABC system and a Bacillus subtilis TatAC-type system recognise three distinct targeting determinants in twin-arginine signal peptides. Mendel S; McCarthy A; Barnett JP; Eijlander RT; Nenninger A; Kuipers OP; Robinson C J Mol Biol 2008 ;375(3):661-72
pdf for mg0565 pubmedlink 18036542

2008

CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. Hendriksen WT; Bootsma HJ; Estevao S; Hoogenboezem T; de Jong A; de Groot R; Kuipers OP; Hermans PW J Bacteriol 2008 ;190(2):590-601
pdf for mg0564 pubmedlink 18024519

2008

LmrR is a transcriptional repressor of expression of the multidrug ABC transporter LmrCD in Lactococcus lactis. Agustiandari H; Lubelski J; van den Berg van Saparoea HB; Kuipers OP; Driessen AJ J Bacteriol 2008 ;190(2):759-63
pdf for mg0563 pubmedlink 17993533

2008

A minimal Tat system from a gram-positive organism: a bifunctional TatA subunit participates in discrete TatAC and TatA complexes. Barnett JP; Eijlander RT; Kuipers OP; Robinson C J Biol Chem 2008 ;283(5):2534-2542
pdf for mg0556 pubmedlink 18029357

2008

Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin. Lubelski J; Rink R; Khusainov R; Moll GN; Kuipers OP Cell Mol Life Sci 2008 ;65(3):455-476
pdf for mg0553 pubmedlink 17965835

2008

NisC, the Cyclase of the Lantibiotic Nisin, Can Catalyze Cyclization of Designed Nonlantibiotic Peptides. Rink R; Kluskens LD; Kuipers A; Driessen AJ; Kuipers OP; Moll GN Biochemistry 2007 ;46(45):13179-13189
pdf for mg0552 pubmedlink 17929939

2007

Comparative analyses of prophage-like elements present in two Lactococcus lactis strains. Ventura M; Zomer A; Canchaya C; O'Connell-Motherway M, Kuipers O, Turrroni F, Ribbera A, Foroni E, Buist G, Wegmann U, Shearman C, Gasson MJ, Fitzgerald GF, Kok J, van Sinderen D Appl Environ Microbiol 2007 ;73(23):7771-7780
pdf for mg0551 pubmedlink 17933937

2007

Enhanced production of pediocin PA-1 in wild nisin- and non-nisin-producing Lactococcus lactis strains of dairy origin Reviriego C; Fernandez L; Kuipers OP; Kok J; Rodriguez JM International Dairy Journal 2007 ;17(5):574-577
pdf for mg0550

2007

Identification of a novel streptococcal gene cassette mediating SOS mutagenesis in Streptococcus uberis. Varhimo E; Savijoki K; Jalava J; Kuipers OP; Varmanen P J Bacteriol 2007 ;189(14):5210-22
pdf for mg0549 pubmedlink 17513475

2007

Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis. Smits WK; Bongiorni C; Veening JW; Hamoen LW; Kuipers OP; Perego M Mol Microbiol 2007 ;65(1):103-20
pdf for mg0548 pubmedlink 17581123

2007

Search for genes essential for pneumococcal transformation: the RadA DNA repair protein plays a role in genomic recombination of donor DNA. Burghout P; Bootsma HJ; Kloosterman TG; Bijlsma JJ; de Jongh CE; Kuipers OP; Hermans PW J Bacteriol 2007 ;189(18):6540-6550
pdf for mg0547 pubmedlink 17631629

2007

The novel transcriptional regulator SczA mediates protection against Zn(2+) stress by activation of the Zn(2+)-resistance gene czcD in Streptococcus pneumoniae. Kloosterman TG; van der Kooi-Pol MM; Bijlsma JJ; Kuipers OP Mol Microbiol 2007 ;65(4):1049-63
pdf for mg0546 pubmedlink 17640279

2007

MOVE: A Multi-level Ontology-based Visualization and Exploration framework for genomic networks. Bosman DW; Blom EJ; Ogao PJ; Kuipers OP; Roerdink JB In Silico Biol 2007 ;7(1):35-59
pdf for mg0545 pubmedlink 17688427

2007

Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation. Rink R; Wierenga J; Kuipers A; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN Appl Environ Microbiol 2007 ;73(18):5809-5816
pdf for mg0544 pubmedlink 17660303

2007

Production and Secretion Stress Caused by Overexpression of Heterologous {alpha}-Amylase Leads to Inhibition of Sporulation and a Prolonged Motile Phase in Bacillus subtilis. Lulko AT; Veening JW; Buist G; Smits WK; Blom EJ; Beekman AC; Bron S; Kuipers OP Appl Environ Microbiol 2007 ;73(16):5354-62
pdf for mg0543 pubmedlink 17586671

2007

SPxB regulates o-acetylation dependent resistance of lactococcus lactis peptidoglycan to hydrolysis. Veiga P; Bulbarela-Sampieri C; Furlan S; Maisons A; Chapot-Chartier MP; Erkelenz M; Mervelet P; Noirot P; Frees D; Kuipers O; Kok J; Gruss A; Buist G; Kulakauskas S J Biol Chem 2007 ;282(27):19342-19354
pdf for mg0539 pubmedlink 17485463

2007

Antirepression as a second mechanism of transcriptional activation by a minor groove binding protein. Smits WK; Hoa TT; Hamoen LW; Kuipers OP; Dubnau D Mol Microbiol 2007 ;64(2):368-81
pdf for mg0538 pubmedlink 17493123

2007

Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the lactococcal two-component system CesSR. Martinez B; Zomer AL; Rodriguez A; Kok J; Kuipers OP Mol Microbiol 2007 ;64(2):473-86
pdf for mg0537 pubmedlink 17493129

2007

A single, specific thymine mutation in the ComK-binding site severely decreases binding and transcription activation by the competence transcription factor ComK of Bacillus subtilis. Susanna KA; Mironczuk AM; Smits WK; Hamoen LW; Kuipers OP J Bacteriol 2007 ;189(13):4718-4728
pdf for mg0536 pubmedlink 17468244

2007

Novel methods for genetic transformation of natural Bacillus subtilis isolates used to study regulation of the mycosubtilin and surfactin synthetases. Duitman EH; Wyczawski D; Boven LG; Venema G; Kuipers OP; Hamoen LW Appl Environ Microbiol 2007 ;73(11):3490-3496
pdf for mg0535 pubmedlink 17416694

2007

The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Romero D; de Vicente A; Rakotoaly RH; Dufour SE; Veening JW; Arrebola E; Cazorla FM; Kuipers OP; Paquot M; Perez-Garcia A Mol Plant Microbe Interact 2007 ;20(4):430-40
pubmedlink 17427813

2007

Two minimal Tat translocases in Bacillus. Jongbloed JD; Grieger U; Antelmann H; Hecker M; Nijland R; Bron S; van Dijl JM Mol Microbiol 2004 ;54(5):1319-25
pdf for mg0532 pubmedlink 15554971

2004

The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363. Wegmann U; O'Connell-Motherway M; Zomer A; Buist G; Shearman C; Canchaya C; Ventura M; Goesmann A; Gasson MJ; Kuipers OP; Van Sinderen D; Kok J J Bacteriol 2007 ;189(8):3256-3270
pdf for mg0531 pubmedlink 17307855

2007

A de-repression system based on the Bacillus subtilis sporulation pathway offers dynamic control of heterologous gene expression. Nijland R; Veening JW; Kuipers OP Appl Environ Microbiol 2007 ;73(7):2390-2393
pdf for mg0528 pubmedlink 17293533

2007

MOVE: A Multi-level Ontology-based Visualization and Exploration framework for genomic networks Bosman,D.W.J.;Blom,E.J.;Ogao,P.J.;Kuipers,O.P.;Roerdink,J.B.T.M. In Silico Biology 2006 ;7(0):0-0
pdf for mg0527

2006

Development of Genomic Array Footprinting for the Identification of Conditionally Essential Genes in Streptococcus pneumoniae. Bijlsma JJ; Burghout P; Kloosterman TG; Bootsma HJ; de Jong A; Hermans PW; Kuipers OP Appl Environ Microbiol 2007 ;73(5):1514-1524
pdf for mg0526 pubmedlink 17261526

2007

Production of dehydroamino acid-containing peptides by Lactococcus lactis. Rink R; Wierenga J; Kuipers A; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN Appl Environ Microbiol 2007 ;73(6):1792-1796
pdf for mg0525 pubmedlink 17261515

2007

FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of prokaryotes. Blom EJ; Bosman DW; van Hijum SA; Breitling R; Tijsma L; Silvis R; Roerdink JB; Kuipers OP Bioinformatics 2007 ;23(9):1161-1163
pdf for mg0524 pubmedlink 17237043

2007

Changing a single amino acid in Clostridium perfringens {beta}-toxin affects efficiency of heterologous secretion by Bacillus subtilis. Nijland R; Heerlien R; Hamoen LW; Kuipers OP Appl Environ Microbiol 2007 ;73(5):1586-1593
pdf for mg0523 pubmedlink 17209068

2007

Transcriptome Analysis of Temporal Regulation of Carbon Metabolism by CcpA in Bacillus subtilis Reveals Additional Target Genes. Lulko AT; Buist G; Kok J; Kuipers OP J Mol Microbiol Biotechnol 2007 ;12(1):82-95
pdf for mg0522 pubmedlink 17183215

2007

Heterologous production and secretion of Clostridium perfringens beta-toxoid in closely related Gram-positive hosts. Nijland R; Lindner C; van Hartskamp M; Hamoen LW; Kuipers OP J Biotechnol 2007 ;127(3):361-72
pdf for mg0521 pubmedlink 16959352

2007

SEC-MEDIATED TRANSPORT OF POST-TRANSLATIONALLY DEHYDRATED PEPTIDES IN LACTOCOCCUS LACTIS. Kuipers A; Wierenga J; Rink R; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN Appl Environ Microbiol 2006 ;72(12):7626-7633
pdf for mg0520 pubmedlink 17041158

2006

Regulation of gene expression in Streptococcus pneumoniae by response regulator 09 is Strain-Dependent. Hendriksen WT; Silva N; Bootsma HJ; Blue CE; Paterson GK; Kerr AR; de Jong A; Kuipers OP; Hermans PW; Mitchell TJ J Bacteriol 2007 ;189(4):1382-1389
pdf for mg0519 pubmedlink 17085554

2007

A Disulfide Bond-Containing Alkaline Phosphatase Triggers a BdbC-Dependent Secretion Stress Response in Bacillus subtilis. Darmon E; Dorenbos R; Meens J; Freudl R; Antelmann H; Hecker M; Kuipers OP; Bron S; Quax WJ; Dubois JY; van Dijl JM Appl Environ Microbiol 2006 ;72(11):6876-85
pdf for mg0518 pubmedlink 17088376

2006

Mapping the pathways to staphylococcal pathogenesis by comparative secretomics. Sibbald MJ; Ziebandt AK; Engelmann S; Hecker M; de Jong A; Harmsen HJ; Raangs GC; Stokroos I; Arends JP; Dubois JY; van Dijl JM Microbiol Mol Biol Rev 2006 ;70(3):755-88
pdf for mg0517 pubmedlink 16959968

2006

Mutations in Lactococcus lactis and their Detection Kok, J.; Van den Burg, B. Genetically Engineered Food, Methods and Detection (ed. Knut J. Heller) 2006 ;0(0):248-268

2006

Time-resolved determination of the CcpA regulon of Lactococcus lactis spp. cremoris MG1363. Zomer AL; Buist G; Larsen R; Kok J; Kuipers OP J Bacteriol 2007 ;189(4):1366-1381
pdf for mg0515 pubmedlink 17028270

2007

Functional analysis of the competence transcription factor ComK of Bacillus subtilis by characterization of truncation variants. Susanna KA; Fusetti F; Thunnissen AM; Hamoen LW; Kuipers OP Microbiology 2006 ;152(0):473-83
pdf for mg0514 pubmedlink 16436435

2006

Characterization of the lytic-lysogenic switch of the lactococcal bacteriophage Tuc2009. Kenny JG; Leach S; de la Hoz AB; Venema G; Kok J; Fitzgerald GF; Nauta A; Alonso JC; van Sinderen D Virology 2006 ;347(2):434-46
pdf for mg0513 pubmedlink 16410016

2006

SIMAGE: simulation of DNA-microarray gene expression data. Albers CJ; Jansen RC; Kok J; Kuipers OP; van Hijum SA BMC Bioinformatics 2006 ;7(0):205-0
pdf for mg0512 pubmedlink 16613602

2006

Identification and functional characterization of the Lactococcus lactis CodY-regulated branched-chain amino acid permease BcaP (CtrA). den Hengst CD; Groeneveld M; Kuipers OP; Kok J J Bacteriol 2006 ;188(9):3280-9
pdf for mg0511 pubmedlink 16621821

2006

Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance. Kramer NE; van Hijum SA; Knol J; Kok J; Kuipers OP Antimicrob Agents Chemother 2006 ;50(5):1753-61
pdf for mg0510 pubmedlink 16641446

2006

High-level heterologous production and functional expression of the sec-dependent enterocin P from Enterococcus faecium P13 in Lactococcus lactis. Gutierrez J; Larsen R; Cintas LM; Kok J; Hernandez PE Appl Microbiol Biotechnol 2006 ;72(1):41-51
pdf for mg0509 pubmedlink 16416297

2006

Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. Kloosterman TG; Hendriksen WT; Bijlsma JJ; Bootsma HJ; van Hijum SA; Kok J; Hermans PW; Kuipers OP J Biol Chem 2006 ;281(35):25097-109
pdf for mg0508 pubmedlink 16787930

2006

GlnR-mediated regulation of nitrogen metabolism in Lactococcus lactis. Larsen R; Kloosterman TG; Kok J; Kuipers OP J Bacteriol 2006 ;188(13):4978-82
pdf for mg0507 pubmedlink 16788206

2006

BAGEL: a web-based bacteriocin genome mining tool. de Jong A; van Hijum SA; Bijlsma JJ; Kok J; Kuipers OP Nucleic Acids Res 2006 ;34(0):0-9
pdf for mg0506 pubmedlink 16845009

2006

The a-phosphoglucomutase of lactococcus lactis is unrelated to the a-D-phosphohexomutase superfamily and encoded by the essential gene pgmH. Neves AR; Pool WA; Castro R; Mingote A; Santos F; Kok J; Kuipers OP; Santos H J Biol Chem 2006 ;281(48):36864-36873
pdf for mg0504 pubmedlink 16980299

2006

Different subcellular locations of secretome components of Gram-positive bacteria. Buist G; Ridder AN; Kok J; Kuipers OP Microbiology 2006 ;152(0):2867-74
pdf for mg0502 pubmedlink 17005968

2006

Natural sweetening of food products by engineering Lactococcus lactis for glucose production. Pool WA; Neves AR; Kok J; Santos H; Kuipers OP Metab Eng 2006 ;8(5):456-64
pdf for mg0500 pubmedlink 16844396

2006

An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Hasper HE; Kramer NE; Smith JL; Hillman JD; Zachariah C; Kuipers OP; de Kruijff B; Breukink E Science 2006 ;313(5793):1636-7
pdf for mg0499 pubmedlink 16973881

2006

Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media. Veening JW; Smits WK; Hamoen LW; Kuipers OP J Appl Microbiol 2006 ;101(3):531-41
pdf for mg0498 pubmedlink 16907804

2006

LmrCD is a major multidrug resistance transporter in Lactococcus lactis. Lubelski J; de Jong A; van Merkerk R; Agustiandari H; Kuipers OP; Kok J; Driessen AJ Mol Microbiol 2006 ;61(3):771-81
pdf for mg0497 pubmedlink 16879641

2006

Ripening of gouda cheese using genetically modified Lactococcus lactis starters Bockelmann, W; Golecki, S; Kok, J; Mierau, I; Heller, KJ Kieler Milchwirtschaftliche Forschungsberichte 2005 ;57(0):263-272

2005

Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations. Ramasamy R; Yasawardena S; Zomer A; Venema G; Kok J; Leenhouts K Vaccine 2006 ;24(18):3900-8
pdf for mg0495 pubmedlink 16545511

2006

Effects of Phosphorelay Perturbations on Architecture, Sporulation, and Spore Resistance in Biofilms of Bacillus subtilis. Veening JW; Kuipers OP; Brul S; Hellingwerf KJ; Kort R J Bacteriol 2006 ;188(8):3099-109
pdf for mg0494 pubmedlink 16585769

2006

Transformation of undomesticated strains of Bacillus subtilis by protoplast electroporation. Romero D; Perez-Garcia A; Veening JW; de Vicente A; Kuipers OP J Microbiol Methods 2006 ;66(3):556-559
pdf for mg0493 pubmedlink 16503058

2006

Phenotypic variation in bacteria: the role of feedback regulation. Smits WK; Kuipers OP; Veening JW Nat Rev Microbiol 2006 ;4(4):259-71
pdf for mg0492 pubmedlink 16541134

2006

Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria. van Roosmalen ML; Kanninga R; El Khattabi M; Neef J; Audouy S; Bosma T; Kuipers A; Post E; Steen A; Kok J; Buist G; Kuipers OP; Robillard G; Leenhouts K Methods 2006 ;38(2):144-9
pdf for mg0491 pubmedlink 16414272

2006

To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae Kloosterman TG; Bijlsma JJ; Kok J; Kuipers OP Microbiology 2006 ;152(0):351-9
pdf for mg0490 pubmedlink 16436423

2006

Development and characterization of a subtilin-regulated expression system in Bacillus subtilis: strict control of gene expression by addition of subtilin. Bongers RS; Veening JW; Van Wieringen M; Kuipers OP; Kleerebezem M Appl Environ Microbiol 2005 ;71(12):8818-24
pdf for mg0488 pubmedlink 16332878

2005

The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element. den Hengst CD; van Hijum SA; Geurts JM; Nauta A; Kok J; Kuipers OP J Biol Chem 2005 ;280(40):34332-42
pdf for mg0487 pubmedlink 16040604

2005

Expression of Transcription Activator ComK of Bacillus subtilis in the Heterologous Host Lactococcus lactis Leads to a Genome-Wide Repression Pattern: a Case Study of Horizontal Gene Transfer. Susanna KA; den Hengst CD; Hamoen LW; Kuipers OP Appl Environ Microbiol 2006 ;72(1):404-11
pdf for mg0485 pubmedlink 16391071

2006

Novel surface display system for proteins on non-genetically modified gram-positive bacteria. Bosma T; Kanninga R; Neef J; Audouy SA; van Roosmalen ML; Steen A; Buist G; Kok J; Kuipers OP; Robillard G; Leenhouts K Appl Environ Microbiol 2006 ;72(1):880-9
pdf for mg0484 pubmedlink 16391130

2006

Positive role of peptidoglycan breaks in lactococcal biofilm formation. Mercier C; Durrieu C; Briandet R; Domakova E; Tremblay J; Buist G; Kulakauskas S Mol Microbiol 2002 ;46(1):235-43
pdf for mg0482 pubmedlink 12366846

2002

Two homologous oligopeptide binding protein genes (oppA) in Lactococcus lactis opp2 [corrected] Sanz Y; Lanfermeijer FC; Hellendoorn M; Kok J; Konings WN; Poolman B Int J Food Microbiol 2004 ;97(1):9-15
pdf for mg0481 pubmedlink 15527913

2004

The circular bacteriocins gassericin A and circularin A. Kawai Y; Kemperman R; Kok J; Saito T Curr Protein Pept Sci 2004 ;5(5):393-8
pdf for mg0480 pubmedlink 15544534

2004

Specificity and selectivity determinants of peptide transport in Lactococcus lactis and other microorganisms. Doeven MK; Kok J; Poolman B Mol Microbiol 2005 ;57(3):640-9
pdf for mg0479 pubmedlink 16045610

2005

Alternative lactose catabolic pathway in Lactococcus lactis IL1403. Aleksandrzak-Piekarczyk T; Kok J; Renault P; Bardowski J Appl Environ Microbiol 2005 ;71(10):6060-9
pdf for mg0478 pubmedlink 16204522

2005

Bacillus subtilis alpha-phosphoglucomutase is required for normal cell morphology and biofilm formation. Lazarevic V; Soldo B; Medico N; Pooley H; Bron S; Karamata D Appl Environ Microbiol 2005 ;71(1):39-45
pdf for mg0477 pubmedlink 15640167

2005

Post-translational Modification of Therapeutic Peptides By NisB, the Dehydratase of the Lantibiotic Nisin. Kluskens LD; Kuipers A; Rink R; de Boef E; Fekken S; Driessen AJ; Kuipers OP; Moll GN Biochemistry 2005 ;44(38):12827-12834
pdf for mg0476 pubmedlink 16171398

2005

Lactic acid bacteria - Genetics, metabolism and application de Vos WM; Kleerebezem M; Kuipers OP FEMS Microbiol Rev 2005 ;29(3):391-391
pdf for mg0475 pubmedlink 15939504

2005

Comparative and functional genomics of lactococci. Kok J; Buist G; Zomer AL; van Hijum SA; Kuipers OP FEMS Microbiol Rev 2005 ;29(3):411-33
pdf for mg0472 pubmedlink 15936843

2005

Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids. Steen A; Palumbo E; Deghorain M; Cocconcelli PS; Delcour J; Kuipers OP; Kok J; Buist G; Hols P J Bacteriol 2005 ;187(1):114-24
pdf for mg0471 pubmedlink 15601695

2005

Probing direct interactions between CodY and the oppD promoter of Lactococcus lactis. den Hengst CD; Curley P; Larsen R; Buist G; Nauta A; van Sinderen D; Kuipers OP; Kok J J Bacteriol 2005 ;187(2):512-21
pdf for mg0470 pubmedlink 15629923

2005

The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. Albano M; Smits WK; Ho LT; Kraigher B; Mandic-Mulec I; Kuipers OP; Dubnau D J Bacteriol 2005 ;187(6):2010-9
pdf for mg0469 pubmedlink 15743949

2005

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development. Smits WK; Eschevins CC; Susanna KA; Bron S; Kuipers OP; Hamoen LW Mol Microbiol 2005 ;56(3):604-14
pdf for mg0468 pubmedlink 15819618

2005

Interaction between ArgR and AhrC controls regulation of arginine metabolism in Lactococcus lactis. Larsen R; Kok J; Kuipers OP J Biol Chem 2005 ;280(19):19319-30
pdf for mg0467 pubmedlink 15749710

2005

A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. van Hijum SA; de Jong A; Baerends RJ; Karsens HA; Kramer NE; Larsen R; den Hengst CD; Albers CJ; Kok J; Kuipers OP BMC Genomics 2005 ;6(1):77-0
pdf for mg0466 pubmedlink 15907200

2005

Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis. Veening JW; Hamoen LW; Kuipers OP Mol Microbiol 2005 ;56(6):1481-94
pdf for mg0465 pubmedlink 15916600

2005

Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and DNA-binding site. Barriere C; Veiga-da-Cunha M; Pons N; Guedon E; van Hijum SA; Kok J; Kuipers OP; Ehrlich DS; Renault P J Bacteriol 2005 ;187(11):3752-61
pdf for mg0464 pubmedlink 15901699

2005

Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis. Smits WK; Dubois JY; Bron S; van Dijl JM; Kuipers OP J Bacteriol 2005 ;187(12):3921-30
pdf for mg0463 pubmedlink 15937154

2005

AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning. Steen A; Buist G; Horsburgh GJ; Venema G; Kuipers OP; Foster SJ; Kok J FEBS J 2005 ;272(11):2854-68
pdf for mg0462 pubmedlink 15943817

2005

Overview on sugar metabolism and its control in Lactococcus lactis . The input from in vivo NMR. Neves AR; Pool WA; Kok J; Kuipers OP; Santos H FEMS Microbiol Rev 2005 ;0(0):0-0
pdf for mg0460 pubmedlink 15939503

2005

Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes. Rink R; Kuipers A; de Boef E; Leenhouts KJ; Driessen AJ; Moll GN; Kuipers OP Biochemistry 2005 ;44(24):8873-82
pdf for mg0458 pubmedlink 15952794

2005

Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies. van Hijum SA; Zomer AL; Kuipers OP; Kok J Nucleic Acids Res 2005 ;33(0):0-6
pdf for mg0457 pubmedlink 15980536

2005

Resistance of Gram-positive bacteria to nisin is not determined by Lipid II levels. Kramer NE; Smid EJ; Kok J; De Kruijff B; Kuipers OP; Breukink E FEMS Microbiol Lett 2004 ;239(1):157-161
pdf for mg0454 pubmedlink 15451114

2004

Subcellular sites for bacterial protein export. Campo N; Tjalsma H; Buist G; Stepniak D; Meijer M; Veenhuis M; Westermann M; Muller JP; Bron S; Kok J; Kuipers OP; Jongbloed JD Mol Microbiol 2004 ;53(6):1583-99
pdf for mg0453 pubmedlink 15341641

2004

Casitone-mediated expression of the prtP and prtM genes in Lactococcus lactis subsp. lactis BGIS29. Miladinov N; Kuipers OP; Topisirovic L Arch Microbiol 2001 ;177(1):54-61
pdf for mg0452 pubmedlink 11797045

2001

A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress. Hyyrylainen HL; Bolhuis A; Darmon E; Muukkonen L; Koski P; Vitikainen M; Sarvas M; Pragai Z; Bron S; van Dijl JM; Kontinen VP Mol Microbiol 2001 ;41(5):1159-72
pdf for mg0451 pubmedlink 11555295

2001

Hierarchical control versus autoregulation of carbohydrate utilization in bacteria. Gunnewijk MG; van den Bogaard PT; Veenhoff LM; Heuberger EH; de Vos WM; Kleerebezem M; Kuipers OP; Poolman B J Mol Microbiol Biotechnol 2001 ;3(3):401-13
pubmedlink 11361071

2001

The role of cold-shock proteins in low-temperature adaptation of food-related bacteria. Wouters JA; Rombouts FM; Kuipers OP; de Vos WM; Abee T Syst Appl Microbiol 2000 ;23(2):165-73
pubmedlink 10930067

2000

Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus. Sabat A; Kosowska K; Poulsen K; Kasprowicz A; Sekowska A; van Den Burg B; Travis J; Potempa J Infect Immun 2000 ;68(2):973-6
pdf for mg0448 pubmedlink 10639475

2000

Characteristics of the biologically active 35-kDa metalloprotease virulence factor from Listeria monocytogenes. Coffey A; van den Burg B; Veltman R; Abee T J Appl Microbiol 2000 ;88(1):132-41
pdf for mg0447 pubmedlink 10735252

2000

A single calcium binding site is crucial for the calcium-dependent thermal stability of thermolysin-like proteases. Veltman OR; Vriend G; Berendsen HJ; Van den Burg B; Venema G; Eijsink VG Biochemistry 1998 ;37(15):5312-9
pdf for mg0446 pubmedlink 9548763

1998

Probing catalytic hinge bending motions in thermolysin-like proteases by glycine --> alanine mutations. Veltman OR; Eijsink VG; Vriend G; de Kreij A; Venema G; Van den Burg B Biochemistry 1998 ;37(15):5305-11
pdf for mg0445 pubmedlink 9548762

1998

Rendering one autolysis site in Bacillus subtilis neutral protease resistant to cleavage reveals a new fission. Van den Burg B; Eijsink VG; Vriend G; Veltman OR; Venema G Biotechnol Appl Biochem 1998 ;27(0):125-32
pubmedlink 9569607

1998

The Sip(Sli) gene of Streptomyces lividans TK24 specifies an unusual signal peptidase with a putative C-terminal transmembrane anchor. Schacht S; Van Mellaert L; Lammertyn E; Tjalsma H; van Dijl JM; Bron S; Anne J DNA Seq 1998 ;9(2):79-88
pubmedlink 10520736

1998

Identification of a sodium chloride-regulated promoter in Lactococcus lactis by single-copy chromosomal fusion with a reporter gene. Sanders JW; Venema G; Kok J; Leenhouts K Mol Gen Genet 1998 ;257(6):681-5
pubmedlink 9604892

1998

Characterization of the divergent sacBK and sacAR operons, involved in sucrose utilization by Lactococcus lactis. Luesink EJ; Marugg JD; Kuipers OP; de Vos WM J Bacteriol 1999 ;181(6):1924-6
pdf for mg0441 pubmedlink 10074089

1999

Molecular characterization of the Lactococcus lactis ptsHI operon and analysis of the regulatory role of HPr. Luesink EJ; Beumer CM; Kuipers OP; De Vos WM J Bacteriol 1999 ;181(3):764-71
pdf for mg0440 pubmedlink 9922238

1999

Lantibiotics: biosynthesis, mode of action and applications. van Kraaij C; de Vos WM; Siezen RJ; Kuipers OP Nat Prod Rep 1999 ;16(5):575-87
pubmedlink 10584332

1999

Genomics for food biotechnology: prospects of the use of high-throughput technologies for the improvement of food microorganisms. Kuipers OP Curr Opin Biotechnol 1999 ;10(5):511-6
pdf for mg0438 pubmedlink 10508639

1999

Characterization of natural isolate Lactococcus lactis subsp. lactis BGMN1-5, a strain producing two bacteriocins cell-wall-associated proteinase and showing clumping phenotype. Gajic, O.; Kojic, M; Banina, A; Toposirovic, L.J. Arch. Biol. Sci., Belgrade 1999 ;51(0):69-78

1999

Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein. Bengtsson J; Tjalsma H; Rivolta C; Hederstedt L J Bacteriol 1999 ;181(2):685-8
pdf for mg0436 pubmedlink 9882689

1999

A bacterial signal peptidase enhances processing of a recombinant single chain antibody fragment in insect cells. Ailor E; Pathmanathan J; Jongbloed JD; Betenbaugh MJ Biochem Biophys Res Commun 1999 ;255(2):444-50
pdf for mg0435 pubmedlink 10049728

1999

Proteomics of Protein Secretion by Bacillus subtilis: Separating the \"Secrets\" of the Secretome. Tjalsma H; Antelmann H; Jongbloed JD; Braun PG; Darmon E; Dorenbos R; Dubois JY; Westers H; Zanen G; Quax WJ; Kuipers OP; Bron S; Hecker M; Van Dijl JM Microbiol Mol Biol Rev 2004 ;68(2):207-33
pdf for mg0434 pubmedlink 15187182

2004

The Bacillus secretion stress response is an indicator for alpha-amylase production levels. Westers H; Darmon E; Zanen G; Veening JW; Kuipers OP; Bron S; Quax WJ; Van Dijl JM Lett Appl Microbiol 2004 ;39(1):65-73
pdf for mg0433 pubmedlink 15189290

2004

Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases. Swertz MA; (Bert) De Brock EO; Van Hijum SA; De Jong A; Buist G; Baerends RJ; Kok J; Kuipers OP; Jansen RC Bioinformatics 2004 ;20(0):2075-2083
pdf for mg0430 pubmedlink 15059831

2004

PreP: gene expression data pre-processing. Garcia de la Nava J; van Hijum S; Trelles O Bioinformatics 2003 ;19(17):2328-9
pdf for mg0429 pubmedlink 14630668

2003

Genomics and bioinformatics enhance research on food and gut bacteria. Kuipers OP Curr Opin Biotechnol 2004 ;15(2):83-5
pdf for mg0428 pubmedlink 15081043

2004

Genome2D: a visualization tool for rapid analysis of bacterial transcriptome data. Baerends, R.J.S.; Smits, W.K.; de Jong, A.; Hamoen, L.W.; Kok, J.; Kuipers, O.P. Genome Biology 2004 ;5(5):1-6
pdf for mg0427 pubmedlink 15128451

2004

MicroPreP: a cDNA microarray data pre-processing framework van Hijum, S.A.F.T., Garcia de la Nava, J., Trelles, O., Kok, J., Kuipers, O.P. Applied Bioinformatics 2003 ;2(4):241-244
pdf for mg0426 pubmedlink 15130795

2003

Functional genomic analysis of the Bacillus subtilis Tat pathway for protein secretion. van Dijl JM; Braun PG; Robinson C; Quax WJ; Antelmann H; Hecker M; Muller J; Tjalsma H; Bron S; Jongbloed JD J Biotechnol 2002 ;98(2):243-54
pdf for mg0425 pubmedlink 12141990

2002

Selective contribution of the twin-arginine translocation pathway to protein secretion in Bacillus subtilis. Jongbloed JD; Antelmann H; Hecker M; Nijland R; Bron S; Airaksinen U; Pries F; Quax WJ; van Dijl JM; Braun PG J Biol Chem 2002 ;277(46):44068-78
pdf for mg0424 pubmedlink 12218047

2002

Genetics of Lactic Acid Bacteria (ed. B. Wood) Kok, J.; Buist, G. Kluwer, New York 2003 ;0(0):189-223

2003

Genetically Engineered Food, Methods and Detection (ed. Knut F. Heller) Kok, J.; Van den Burg, B. Wiley-VCH GmbH & Co. KgaA, Weinheim, Germany 2003 ;0(0):231-250

2003

Engineering of quorum-sensing systems for improved production of alkaline protease by Bacillus subtilis. Tjalsma H; Koetje EJ; Kiewiet R; Kuipers OP; Kolkman M; van der Laan J; Daskin R; Ferrari E; Bron S J Appl Microbiol 2004 ;96(3):569-78
pdf for mg0420 pubmedlink 14962137

2004

Differential expression of two paralogous genes of Bacillus subtilis encoding single-stranded DNA binding protein. Lindner C; Nijland R; van Hartskamp M; Bron S; Hamoen LW; Kuipers OP J Bacteriol 2004 ;186(4):1097-105
pdf for mg0419 pubmedlink 14762004

2004

Mechanism of transcription activation at the comG promoter by the competence transcription factor ComK of Bacillus subtilis. Susanna KA; van der Werff AF; den Hengst CD; Calles B; Salas M; Venema G; Hamoen LW; Kuipers OP J Bacteriol 2004 ;186(4):1120-8
pdf for mg0418 pubmedlink 14762007

2004

Active lipoprotein precursors in the Gram-positive eubacterium Lactococcus lactis. Venema R; Tjalsma H; van Dijl JM; de Jong A; Leenhouts K; Buist G; Venema G J Biol Chem 2003 ;278(17):14739-46
pdf for mg0417 pubmedlink 12584195

2003

Essential Bacillus subtilis genes. Kobayashi K; Ehrlich SD; Albertini A; Amati G; Andersen KK; Arnaud M; Asai K; Ashikaga S; Aymerich S; Bessieres P; Boland F; Brignell SC; Bron S; Bunai K; Chapuis J; Christiansen LC; Danchin A; Debarbouille M; Dervyn E; Deuerling E; Devine K; Devine SK; Dreesen O; Errington J; Fillinger S; Foster SJ; Fujita Y; Galizzi A; Gardan R; Eschevins C; Fukushima T; Haga K; Harwood CR; Hecker M; Hosoya D; Hullo MF; Kakeshita H; Karamata D; Kasahara Y; Kawamura F; Koga K; Koski P; Kuwana R; Imamura D; Ishimaru M; Ishikawa S; Ishio I; Le Coq D; Masson A; Mauel C; Meima R; Mellado RP; Moir A; Moriya S; Nagakawa E; Nanamiya H; Nakai S; Nygaard P; Ogura M; Ohanan T; O\ Proc Natl Acad Sci U S A 2003 ;100(8):4678-83
pdf for mg0416 pubmedlink 12682299

2003

Complementary impact of paralogous Oxa1-like proteins of Bacillus subtilis on post-translocational stages in protein secretion. Tjalsma H; Bron S; van Dijl JM J Biol Chem 2003 ;278(18):15622-32
pdf for mg0415 pubmedlink 12586834

2003

Complete genome sequence of Lactobacillus plantarum WCFS1. Kleerebezem M; Boekhorst J; van Kranenburg R; Molenaar D; Kuipers OP; Leer R; Tarchini R; Peters SA; Sandbrink HM; Fiers MW; Stiekema W; Lankhorst RM; Bron PA; Hoffer SM; Groot MN; Kerkhoven R; de Vries M; Ursing B; de Vos WM; Siezen RJ Proc Natl Acad Sci U S A 2003 ;100(4):1990-5
pdf for mg0414 pubmedlink 12566566

2003

The extracellular proteome of Bacillus subtilis under secretion stress conditions. Antelmann H; Darmon E; Noone D; Veening JW; Westers H; Bron S; Kuipers OP; Devine KM; Hecker M; van Dijl JM Mol Microbiol 2003 ;49(1):143-56
pdf for mg0413 pubmedlink 12823817

2003

Genome engineering reveals large dispensable regions in Bacillus subtilis. Westers H; Dorenbos R; van Dijl JM; Kabel J; Flanagan T; Devine KM; Jude F; Seror SJ; Beekman AC; Darmon E; Eschevins C; de Jong A; Bron S; Kuipers OP; Albertini AM; Antelmann H; Hecker M; Zamboni N; Sauer U; Bruand C; Ehrlich DS; Alonso JC; Salas M; Quax WJ Mol Biol Evol 2003 ;20(12):2076-90
pdf for mg0412 pubmedlink 12949151

2003

Purification and characterisation of a lactococcal aminoacylase. Curley P; van der Does C; Driessen AJ; Kok J; van Sinderen D Arch Microbiol 2003 ;179(6):402-8
pdf for mg0411 pubmedlink 12682714

2003

Novel mechanism of bacteriocin secretion and immunity carried out by lactococcal multidrug resistance proteins. Gajic O; Buist G; Kojic M; Topisirovic L; Kuipers OP; Kok J J Biol Chem 2003 ;278(36):34291-8
pdf for mg0410 pubmedlink 12801935

2003

UniFrag and GenomePrimer: selection of primers for genome-wide production of unique amplicons. van Hijum SA; de Jong A; Buist G; Kok J; Kuipers OP Bioinformatics 2003 ;19(12):1580-2
pdf for mg0409 pubmedlink 12912842

2003

Functional analysis of the gene cluster involved in production of the bacteriocin circularin A by Clostridium beijerinckii ATCC 25752. Kemperman R; Jonker M; Nauta A; Kuipers OP; Kok J Appl Environ Microbiol 2003 ;69(10):5839-48
pdf for mg0408 pubmedlink 14532033

2003

Projector: automatic contig mapping for gap closure purposes. van Hijum SA; Zomer AL; Kuipers OP; Kok J Nucleic Acids Res 2003 ;31(22):0-0
pdf for mg0407 pubmedlink 14602937

2003

ArgR and AhrC are both required for regulation of arginine metabolism in Lactococcus lactis. Larsen R; Buist G; Kuipers OP; Kok J J Bacteriol 2004 ;186(4):1147-57
pdf for mg0406 pubmedlink 14762010

2004

Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents. Steen A; Buist G; Leenhouts KJ; El Khattabi M; Grijpstra F; Zomer AL; Venema G; Kuipers OP; Kok J J Biol Chem 2003 ;278(26):23874-81
pdf for mg0404 pubmedlink 12684515

2003

Breakage-reunion and copy choise mechanisms of recombination between short homologous sequences Brunier, D.;Peeters, B.P.H.;Bron,S.;Ehrlich, S.D. The EMBO Journal 1989 ;8(10):3127-3133

1989

Identification and Characterization of Two Novel Clostridial Bacteriocins, Circularin A and Closticin 574 Kemperman, R. ; Kuipers, A. ; Karsens, H. ; Nauta, A. ; Kuipers, O. and Kok, J. Applied and Environmental Microbiology 2003 ;69(0):1589-1597
pdf for mg0401

2003

The mode of replication is a major factor in segregational plasmid instability in Lactococcus lactis Kiewiet,R.;Kok,J.;Seegers,J.F.M.L.;Venema, G.;Bron,S. Appl. Environmen. Microbiol. 1993 ;59(2):358-364

1993

Bacillus subtilis functional genomics: genome-wide analysis of the DegS-DegU regulon by transcriptomics and proteomics. Mader U; Antelmann H; Buder T; Dahl MK; Hecker M; Homuth G Mol Genet Genomics 2002 ;268(4):455-67
pdf for mg0398 pubmedlink 12471443

2002

Qulatitative analysis of gene networks. Thieffry, D.;Thomas, R. Pacific Symp. Biocomp. 1998 ;3(-1):77-88
pdf for mg0395

1998

Dynamical Analysis of Gene Networks Requires Both mRNA and Protein Expression Information Hatzimanikatis V. Metabolic Engineering 1999 ;1(-1):0-0
pdf for mg0394

1999

The Structure of the Transposable Genetic Element ISBsu2 in the Cryptic Plasmid p1516 from a Soil Bacillus subtilis Strain and the Presence of Homologues of This Element in the Chromosomes of Various Bacillus subtilis Strains Holsappel, S.; Gagarina, E.Yu.; Poluektova, E.U.; Nezametdinova, V.z.; Gel'fand, M.S.; Prozorov, A.A.; Bron, S. Microbiology 2003 ;72(0):58-63
pdf for mg0391

2003

The presence of the transposable element ISBsu2 from a cryptic plasmid in chromosomes of some Bacillus subtilis strains. Poluektova EU; Holsappel S; Gagarina EY; Gelfand MS; Bron S; Prozorov AA Dokl Biochem Biophys 2002 ;386(0):275-7
pdf for mg0390 pubmedlink 12474766

2002

Controlling competence in Bacillus subtilis: shared use of regulators. Hamoen LW; Venema G; Kuipers OP Microbiology 2003 ;149(0):9-17
pdf for mg0389 pubmedlink 12576575

2003

Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach. Hamoen LW; Smits WK; Jong Ad A; Holsappel S; Kuipers OP Nucleic Acids Res 2002 ;30(24):5517-28
pdf for mg0388

2002

A plasmid-borne Rap-Phr system of Bacillus subtilis can mediate cell-density controlled production of extracellular proeases Koetje, J.E.; Hajdo-Milasinovic, A.; Kiewiet, R.; Bron, S.; Tjalsma, H. Microbiology 2003 ;149(0):19-28
pdf for mg0387

2003

Recombination in bacterial plasmids and chromosomes Ehrlich, S.D.;Brunier, D.;Peeters, B.; Bron, S.;Janniere, L.;Michel,B.; Sozhamannan,S. 1989 ;0(0):197-203

1989

Protein Secretion in Bacillus subtilis. In; DNA transfer and gene expression in microorganisms van Dijl,J.M.; de Jong, A; Smith,H; Venema, G.; Bron, S. 1993 ;0(0):0-0

1993

Development of a beta-galactosidase alfa-complementation system for molecular cloning in Bacillus subtilis Haima, P.; van Sinderen, D.; Schotting, H., Bron, S,;Venema, G. Gene 1990 ;86(0):63-69

1990

Characterization of the putative replisome organizer of the lactococcal bacteriophage r1t.: Zuniga M, Franke-Fayard B, Venema G, Kok J, Nauta A. Related Articles, Links Zuniga M, Franke-Fayard B, Venema G, Kok J, Nauta A. J Virol. 2002 ;76(20):10234-10244
pdf for mg0375

2002

Environmental stress responses in Lactococcus lactis Sanders,J.W., Venema, G., Kok, J. FEMS Microbioloy Revieuws 1999 ;23(0):483-501
pdf for mg0369

1999

Liposome-enhanced transformation of Streptococcus lactis and plasmid transfer by intergeneric protoplast fusion of Streptococcus lactis and Bacillus subtilis Vossen, van der, J.M.B.M., Kok, J., Lelie, van der D., Venema, G. FEMS Microbiology Letters 1988 ;49(0):323-329
pdf for mg0368

1988

Transfomation of group A streptococci by electroporation Suvorov, A., Kok, J., Venema, G. FEMS Microbiology Letters 1988 ;56(0):95-100
pdf for mg0367

1988

Discovering lactic acid bacteria by genomics Klaenhammer, T., Kuipers. O., Kok. J. Et al. Antonie van Leeuwenhoek 2002 ;82(0):29-58
pdf for mg0366

2002

Pediocin PA-1, a Wide-Spectrum Bacteriocin from Lactic Acid Bacteria Rodriguez, J. M., Martinez, M. I., Kok, J. Critical Revieuws in Food Science and Nutrition 2002 ;42(0):91-121
pdf for mg0365

2002

Transcriptome analysis and related databases of Lactococcus lactis Kuipers, O.P., de Jong, A., Baerends, R.J.S., van Hijum, S.A.F.T., Zomer, A.L., Karsens, H.A., den Hengst, C.D., Kramer, N.E., Buist, B., Kok, J. Antonie van Leeuwenhoek 2002 ;82(0):113-122
pdf for mg0363

2002

Oligopepidase O Mierau,I and Kok.J The Handbook of Proteolytic Enzymes. (Academic Press) 1998 ;0(0):1091-1093
pdf for mg0362

1998

Regulation of carbon catabolism in Lactococcus-lactis Aleksandsak, T,; Kowalczyk, M,;Kok,J.;Bardoski,J. Food Biotechnology 2000 ;66(0):17-61
pdf for mg0361

2000

Broad-host-range shuttle vectors for screening of regulated promoter activity in viridans group streptococci Vriesema A.J.M.;Brinkman R.;Kok.J.;Zaat S.A.J. Applied and Environmental Microbiology 2000 ;66(0):535-542
pdf for mg0360

2000

The effects of modifying the suface charge on the catalytic activity of a thermolysin-like protease. de Kreij,A.;van den Burg,B.;Venema,G.;Vriend,G.;Eijsink,V.G.;Nielsen,J.E. J.Biol.Chem. 2002 ;277(18):15432-15438
pdf for mg0356

2002

Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis Fernandez, M., Kleerebezem, M., Kuipers, O. P., Siezen, R. J.,van Kranenburg, R. J Bacteriol 2002 ;184(1):82-90
pdf for mg0354

2002

Protein Transport Pathways in Bacillus subtilis: a Genome-Based Road Map van Dijl, J. M., Bolhuis, A., Tjalsma, H., Jongbloed, J. D., de Jong, A.,Bron, S. Bacillus subtilis and its Closest Relatives: From Genes to Cells 2002 ;24(0):337-355
pdf for mg0353

2002

The Eubacterial Lipoprotein-Specific (Type II) Signal Peptidase Tjalsma, H., Zanen, G., Bron, S.,van Dijl, J. M. The Enzymes 2001 ;0(0):3-26

2001

The effect of changing the hydrophobic S1' subsite of thermolysin-like proteases on substrate specificity de Kreij, A., van den Burg, B., Veltman, O. R., Vriend, G., Venema, G.,Eijsink, V. G. Eur.J Biochem 2001 ;268(18):4985-4991
pdf for mg0351

2001

The Bacillus subtilis competence transcription factor, ComK, overrides LexA-imposed transcriptional inhibition without physically displacing LexA Hamoen, L. W., Haijema, B. J., Bijlsma, J. J., Venema, G.,Lovett, C. M. J Biol Chem 2001 ;276(46):42901-42907
pdf for mg0349

2001

Structural and functional analysis of a bipolar replication terminus. Implications for the origin of polarity of fork arrest Mohanty, B. K., Bussiere, D. E., Sahoo, T., Pai, K. S., Meijer, W. J., Bron, S.,Bastia, D. J Biol Chem 2001 ;276(16):13160-13168
pdf for mg0347

2001

Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity Wiedemann, I., Breukink, E., van Kraaij, C., Kuipers, O. P., Bierbaum, G., de Kruijff, B.,Sahl, H. G. J Biol Chem 2001 ;276(3):1772-1779
pdf for mg0346

2001

Regulatory functions of serine-46-phosphorylated HPr in Lactococcus lactis Monedero, V., Kuipers, O. P., Jamet, E.,Deutscher, J. J Bacteriol 2001 ;183(11):3391-3398
pdf for mg0345

2001

Regulation of bacteriocin production in Lactobacillus plantarum depends on a conserved promoter arrangement with consensus binding sequence Risoen, P. A., Johnsborg, O., Diep, D. B., Hamoen, L. W., Venema, G.,Nes, I. F. Mol Genet Genomics 2001 ;265(1):198-206
pdf for mg0344

2001

Proteins of the lactococcin A secretion system: lcnD encodes two in-frame proteins Varcamonti, M., Nicastro, G., Venema, G.,Kok, J. FEMS Microbiol Lett. 2001 ;204(2):259-263
pdf for mg0343

2001

Molecular tools for the identification of mutations affecting protein secretion. Meima, R., Eschevins, C., Koski, P., Sarvas, M.,Bron, S. Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):137-143

2001

Membrane topology of the Streptomyces lividans type I signal peptidases Geukens, N., Lammertyn, E., van Mellaert, L., Schacht, S., Schaerlaekens, K., Parro, V., Bron, S., Engelborghs, Y., Mellado, R. P.,Anne, J. J Bacteriol 2001 ;183(16):4752-4760
pdf for mg0341

2001

Distinction between major and minor Bacillus signal peptidases based on phylogenetic and structural criteria van Roosmalen, M. L., Jongbloed, J. D., Dubois, J. Y., Venema, G., Bron, S.,van Dijl, J. M. J Biol Chem 2001 ;276(27):25230-25235
pdf for mg0339

2001

Detergent-independent in vitro activity of a truncated Bacillus signal peptidase van Roosmalen, M. L., Jongbloed, J. D., de Jong, A., van Eerden, J., Venema, G., Bron, S.,van Dijl, J. M. Microbiology 2001 ;147(0):909-917
pdf for mg0338

2001

Complete DNA sequence of Lactococcus lactis adds flavor to genomics Kuipers, O. P. Genome Res 2001 ;11(5):673-674
pdf for mg0337

2001

Cold shock proteins of Lactococcus lactis MG1363 are involved in cryoprotection and in the production of cold-induced proteins Wouters, J. A., Frenkiel, H., de Vos, W. M., Kuipers, O. P.,Abee, T. Appl Environ.Microbiol 2001 ;67(11):5171-5178
pdf for mg0336

2001

Cell processes and macromolecule metabolism: Methods for the selection of mutants in genetic competence, DNA recombination and repair, and protein secretion Meima, R., Eschevins, C.,Bron, S. Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):131-136

2001

Cell processes and macromolecule metabolism: a quest for genes involved in genetic competence, DNA recombination and repair. Meima, R., Eschevins, C.,Bron, S. Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):123-129

2001

Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases Pragai, Z., Eschevins, C., Bron, S.,Harwood, C. R. J Bacteriol 2001 ;183(8):2505-2515
pdf for mg0332

2001

Activation of silent gal genes in the lac-gal regulon of Streptococcus thermophilus Vaughan, E. E., van den Bogaard, P. T., Catzeddu, P., Kuipers, O. P.,de Vos, W. M. J Bacteriol 2001 ;183(4):1184-1194
pdf for mg0331

2001

A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter Kleerebezem, M., Kuipers, O. P., de Vos, W. M., Stiles, M. E.,Quadri, L. E. Peptides 2001 ;22(10):1597-1601
pdf for mg0330

2001

A proteomic view on genome-based signal peptide predictions Antelmann, H., Tjalsma, H., Voigt, B., Ohlmeier, S., Bron, S., van Dijl, J. M.,Hecker, M. Genome Res 2001 ;11(9):1484-1502
pdf for mg0329

2001

The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis Hamoen, L. W., van Werkhoven, A. F., Venema, G.,Dubnau, D. Proc Natl Acad Sci 2000 ;97(16):9246-9251
pdf for mg0326

2000

The membrane-bound H(+)-ATPase complex is essential for growth of Lactococcus lactis Koebmann, B. J., Nilsson, D., Kuipers, O. P.,Jensen, P. R. J Bacteriol 2000 ;182(17):4738-4743
pdf for mg0325

2000

The Evolution of Bacterial Plasmids. Osborn, M., Bron, S., Firth, N., Holsappel, S., Huddleston, A., Kiewiet, R., Meijer, W., Seegers, J. F., Skurray, R., Terpstra, P., Thomas, C. M., Thorsted, P. B., Tietze, E.,Turner, S. L. The Horizontal Gene Pool : Bacterial Plasmids and Gene Spread 2000 ;8(0):301-361

2000

The anaerobic (class III) ribonucleotide reductase from Lactococcus lactis. Catalytic properties and allosteric regulation of the pure enzyme system Torrents, E., Buist, G., Liu, A., Eliasson, R., Kok, J., Gibert, I., Graslund, A.,Reichard, P. J Biol Chem 2000 ;275(4):2463-2471
pdf for mg0323

2000

TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway Jongbloed, J. D., Martin, U., Antelmann, H., Hecker, M., Tjalsma, H., Venema, G., Bron, S., van Dijl, J. M., Müller, J. P. J Biol Chem 2000 ;275(52):41350-41357
pdf for mg0322

2000

Substrate specificity in the highly heterogeneous M4 peptidase family is determined by a small subset of amino acids de Kreij, A., Venema, G.,van den Burg, B. J Biol Chem 2000 ;275(40):31115-31120
pdf for mg0321

2000

Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome Tjalsma, H., Bolhuis, A., Jongbloed, J. D., Bron, S.,van Dijl, J. M. Microbiol Mol Biol Rev 2000 ;64(3):515-547
pdf for mg0320

2000

Requirement of autolytic activity for bacteriocin-induced lysis Martinez-Cuesta, M. C., Kok, J., Herranz, E., Pelaez, C., Requena, T.,Buist, G. Appl Environ.Microbiol 2000 ;66(8):3174-3179
pdf for mg0319

2000

Physiological and regulatory effects of controlled overproduction of five cold shock proteins of Lactococcus lactis MG1363 Wouters, J. A., Mailhes, M., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T. Appl Environ.Microbiol 2000 ;66(9):3756-3763
pdf for mg0318

2000

Molecular and functional analyses of the metC gene of Lactococcus lactis, encoding cystathionine beta-lyase Fernandez, M., van Doesburg, W., Rutten, G. A., Marugg, J. D., Alting, A. C., van Kranenburg, R.,Kuipers, O. P. Appl Environ.Microbiol 2000 ;66(1):42-48
pdf for mg0317

2000

Lactic acid bacteria: the bugs of the new millennium Konings, W. N., Kok, J., Kuipers, O. P.,Poolman, B. Curr Opin Microbiol 2000 ;3(3):276-282
pdf for mg0316

2000

Heterologous coproduction of enterocin A and pediocin PA-1 by Lactococcus lactis: detection by specific peptide-directed antibodies Martinez, J. M., Kok, J., Sanders, J. W.,Hernandez, P. E. Appl Environ.Microbiol 2000 ;66(8):3543-3549
pdf for mg0315

2000

Expression of the neutral protease gene from a thermophilic Bacillus sp. BT1 strain in Bacillus subtilis and its natural host: identification of a functional promoter Vecerek, B.Venema, G. J Bacteriol 2000 ;182(14):4104-4107
pdf for mg0314

2000

Engineering a disulfide bond and free thiols in the lantibiotic nisin Z van Kraaij, C., Breukink, E., Rollema, H. S., Bongers, R. S., Kosters, H. A., de Kruijff, B.,Kuipers, O. P. Eur.J Biochem 2000 ;267(3):901-909
pdf for mg0313

2000

Did the mitochondrial processing peptidase evolve from a eubacterial regulator of gene expression? Bolhuis, A., Koetje, E., Dubois, J. Y., Vehmaanpera, J., Venema, G., Bron, S.,van Dijl, J. M. Mol Biol Evol. 2000 ;17(1):198-201
pdf for mg0312

2000

Current strategies for improving food bacteria Kuipers, O. P., Buist, G.,Kok, J. Res Microbiol 2000 ;151(10):815-822
pdf for mg0311

2000

Control of lactose transport, beta-galactosidase activity, and glycolysis by CcpA in Streptococcus thermophilus: evidence for carbon catabolite repression by a non-phosphoenolpyruvate-dependent phosphotransferase system sugar van den Bogaard, P. T., Kleerebezem, M., Kuipers, O. P.,de Vos, W. M. J Bacteriol 2000 ;182(21):5982-5989
pdf for mg0310

2000

Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis Tjalsma, H., Stover, A.G., Driks, A., Venema, G., Bron, S.,van Dijl, J.M. J Biol Chem 2000 ;275(33):25102-25108
pdf for mg0309

2000

Cloning, characterization, controlled overexpression, and inactivation of the major tributyrin esterase gene of Lactococcus lactis Fernandez, L., Beerthuyzen, M. M., Brown, J., Siezen, R. J., Coolbear, T., Holland, R.,Kuipers, O. P. Appl Environ.Microbiol 2000 ;66(4):1360-1368
pdf for mg0308

2000

Chaperone-like activities of the CsaA protein of Bacillus subtilis Muller, J.P., Bron, S., Venema, G.,van Dijl, J.M. Microbiology 2000 ;146(1):77-88
pdf for mg0307

2000

Changes in glycolytic activity of Lactococcus lactis induced by low temperature Wouters, J. A., Kamphuis, H. H., Hugenholtz, J., Kuipers, O. P., de Vos, W. M.,Abee, T. Appl Environ.Microbiol 2000 ;66(9):3686-3691
pdf for mg0306

2000

Biological and molecular characterization of a two-peptide lantibiotic produced by Lactococcus lactis IFPL105 Martinez-Cuesta, M. C., Buist, G., Kok, J., Hauge, H. H., Nissen-Meyer, J., Pelaez, C.,Requena, T. J Appl Microbiol 2000 ;89(2):249-260
pdf for mg0305

2000

Bile salt hydrolase of Bifidobacterium longum-biochemical and genetic characterization Tanaka, H., Hashiba, H., Kok, J.,Mierau, I. Appl Environ.Microbiol 2000 ;66(6):2502-2512
pdf for mg0304

2000

A truncated soluble Bacillus signal peptidase produced in Escherichia coli is subject to self-cleavage at its active site van Roosmalen, M. L., Jongbloed, J. D., Kuipers, A., Venema, G., Bron, S.,van Dijl, J. M. J Bacteriol 2000 ;182(20):5765-5770
pdf for mg0303

2000

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic Breukink, E., Wiedemann, I., van Kraaij, C., Kuipers, O. P., Sahl, H.,de Kruijff, B. Science 1999 ;286(5448):2361-2364
pdf for mg0302

1999

The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein Tjalsma, H., Kontinen, V. P., Pragai, Z., Wu, H., Meima, R., Venema, G., Bron, S., Sarvas, M.,van Dijl, J. M. J Biol Chem 1999 ;274(3):1698-1707
pdf for mg0301

1999

The potential active site of the lipoprotein-specific (type II) signal peptidase of Bacillus subtilis Tjalsma, H., Zanen, G., Venema, G., Bron, S.,van Dijl, J. M. J Biol Chem 1999 ;274(40):28191-28197
pdf for mg0300

1999

The plasmid-encoded signal peptidase SipP can functionally replace the major signal peptidases SipS and SipT of Bacillus subtilis Tjalsma, H., van den Dolder, J., Meijer, W. J., Venema, G., Bron, S.,van Dijl, J. M. J Bacteriol 1999 ;181(8):2448-2454
pdf for mg0299

1999

The mycosubtilin synthetase of Bacillus subtilis ATCC6633: a multifunctional hybrid between a peptide synthetase, an amino transferase, and a fatty acid synthase Duitman, E. H., Hamoen, L. W., Rembold, M., Venema, G., Seitz, H., Saenger, W., Bernhard, F., Reinhardt, R., Schmidt, M., Ullrich, C., Stein, T., Leenders, F.,Vater, J. Proc Natl Acad Sci U S A 1999 ;96(23):13294-13299
pdf for mg0298

1999

Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and processing of secretory proteins Bolhuis, A., Matzen, A., Hyyrylainen, H. L., Kontinen, V. P., Meima, R., Chapuis, J., Venema, G., Bron, S., Freudl, R.,van Dijl, J. M. J Biol Chem 1999 ;274(35):24585-24592
pdf for mg0297

1999

Molecular Biology and Genetics of Bacillus spp. Bron, S., Meima, R., van Dijl, J. M., Wipat, A.,Harwood, C. R. Manual of Industrial Microbiology and Biotechnology 1999 ;0(0):392-416
pdf for mg0296

1999

Membrane topology of the lactococcal bacteriocin ATP-binding cassette transporter protein LcnC. Involvement of LcnC in lactococcin a maturation Franke, C. M., Tiemersma, J., Venema, G.,Kok, J. J Biol Chem 1999 ;274(13):8484-8490
pdf for mg0295

1999

Introduction of peptidase genes from Lactobacillus delbrueckii subsp. lactis into Lactococcus lactis and controlled expression Wegmann, U., Klein, J. R., Drumm, I., Kuipers, O. P.,Henrich, B. Appl Environ.Microbiol 1999 ;65(11):4729-4733
pdf for mg0293

1999

Functional analysis of paralogous thiol-disulfide oxidoreductases in Bacillus subtilis Bolhuis, A., Venema, G., Quax, W. J., Bron, S.,van Dijl, J. M. J Biol Chem 1999 ;274(35):24531-24538
pdf for mg0291

1999

From DNA sequence to application: possibilities and complications Venema, G., Kok, J.,van Sinderen, D. Antonie Van Leeuwenhoek 1999 ;76(1):3-23
pdf for mg0290

1999

Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis Bolhuis, A., Tjalsma, H., Smith, H. E., de Jong, A., Meima, R., Venema, G., Bron, S.,van Dijl, J. M. Appl Environ.Microbiol 1999 ;65(7):2934-2941
pdf for mg0289

1999

Effects of gene disruptions in the nisin gene cluster of Lactococcus lactis on nisin production and producer immunity Ra, R., Beerthuyzen, M. M., de Vos, W. M., Saris, P. E.,Kuipers, O. P. Microbiology 1999 ;145(0):1227-1233
pdf for mg0288

1999

DNA-microarrays and food-biotechnology Kuipers, O. P., de Jong, A., Holsappel, S., Bron, S., Kok, J.,Hamoen, L. W. Antonie Van Leeuwenhoek 1999 ;76(1):353-355
pdf for mg0287

1999

Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants Bolhuis, A., Tjalsma, H., Stephenson, K., Harwood, C. R., Venema, G., Bron, S.,van Dijl, J. M. J Biol Chem 1999 ;274(22):15865-15868
pdf for mg0286

1999

Cold shock proteins and low-temperature response of Streptococcus thermophilus CNRZ302 Wouters, J. A., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T. Appl Environ.Microbiol 1999 ;65(10):4436-4442
pdf for mg0285

1999

Characterization of a novel stable biocatalyst obtained by protein engineering van den Burg, B., de Kreij, A., Van der Veek, P., Mansfeld, J.,Venema, G. Biotechnol Appl Biochem 1999 ;30(0):35-40
pdf for mg0284

1999

Anchoring of proteins to lactic acid bacteria Leenhouts, K. J., Buist, G.,Kok, J. Antonie Van Leeuwenhoek 1999 ;76(1):367-376
pdf for mg0283

1999

Analysis of the role of 7 kDa cold-shock proteins of Lactococcus lactis MG1363 in cryoprotection Wouters, J. A., Jeynov, B., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T. Microbiology 1999 ;145(0):3185-3194
pdf for mg0282

1999

Use of a genetically enhanced, pediocin-producing starter culture, lactococcus lactis subsp. lactis MM217, To control listeria monocytogenes in cheddar cheese Buyong, N., Kok, J.,Luchansky, J. B. Appl Environ.Microbiol 1998 ;64(12):4842-4845
pdf for mg0281

1998

The S-layer gene of Lactobacillus helveticus CNRZ 892: cloning, sequence and heterologous expression Callegari, M. L., Riboli, B., Sanders, J. W., Cocconcelli, P. S., Kok, J., Venema, G.,Morelli, L. Microbiology 1998 ;144(0):719-726
pdf for mg0280

1998

The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix Hamoen, L. W., van Werkhoven, A. F., Bijlsma, J. J., Dubnau, D.,Venema, G. Genes Dev. 1998 ;12(10):1539-1550
pdf for mg0278

1998

The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene Noback, M. A., Holsappel, S., Kiewiet, R., Terpstra, P., Wambutt, R., Wedler, H., Venema, G.,Bron, S. Microbiology 1998 ;144(0):859-875
pdf for mg0277

1998

Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: possible recognition sites for DNA topoisomerase I Meima, R., Haan, G. J., Venema, G., Bron, S.,de Jong, S. Nucleic Acids Res 1998 ;26(10):2366-2373
pdf for mg0276

1998

SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins Bolhuis, A., Broekhuizen, C. P., Sorokin, A., van Roosmalen, M. L., Venema, G., Bron, S., Quax, W. J.,van Dijl, J. M. J Biol Chem 1998 ;273(33):21217-21224
pdf for mg0275

1998

Rolling-circle plasmids from Bacillus subtilis: complete nucleotide sequences and analyses of genes of pTA1015, pTA1040, pTA1050 and pTA1060, and comparisons with related plasmids from gram-positive bacteria Meijer, W. J., Wisman, G. B., Terpstra, P., Thorsted, P. B., Thomas, C. M., Holsappel, S., Venema, G.,Bron, S. FEMS Microbiol Rev. 1998 ;21(4):337-368
pdf for mg0274

1998

Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli Bron, S., Bolhuis, A., Tjalsma, H., Holsappel, S., Venema, G.,van Dijl, J. M. J Biotechnol 1998 ;64(1):3-13
pdf for mg0272

1998

Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases Tjalsma, H., Bolhuis, A., van Roosmalen, M. L., Wiegert, T., Schumann, W., Broekhuizen, C. P., Quax, W. J., Venema, G., Bron, S.,van Dijl, J. M. Genes Dev. 1998 ;12(15):2318-2331
pdf for mg0269

1998

Engineering an enzyme to resist boiling van den Burg, B., Vriend, G., Veltman, O. R., Venema, G.,Eijsink, V. G. Proc Natl Acad Sci U S A 1998 ;95(5):2056-2060
pdf for mg0268

1998

Early steps in the unfolding of thermolysin-like proteases Vriend, G., Berendsen, H. J., van den Burg, B., Venema, G.,Eijsink, V. G. J Biol Chem 1998 ;273(52):35074-35077
pdf for mg0267

1998

Construction of a food-grade multiple-copy integration system for Lactococcus lactis Leenhouts, K. J., Bolhuis, A., Venema, G.,Kok, J. Appl Microbiol Biotechnol 1998 ;49(4):417-423
pdf for mg0266

1998

Clustered organization and transcriptional analysis of a family of five csp genes of Lactococcus lactis MG1363 Wouters, J. A., Sanders, J. W., Kok, J., de Vos, W. M., Kuipers, O. P.,Abee, T. Microbiology 1998 ;144(0):2885-2893
pdf for mg0265

1998

Cloning, expression, and chromosomal stabilization of the Propionibacterium shermanii proline iminopeptidase gene (pip) for food-grade application in Lactococcus lactis Leenhouts, K. J., Bolhuis, A., Boot, J., Deutz, I., Toonen, M. Y., Venema, G., Kok, J.,Ledeboer, A. M. Appl Environ.Microbiol 1998 ;64(12):4736-4742
pdf for mg0264

1998

Characterization of yhcN, a new forespore-specific gene of Bacillus subtilis Bagyan, I., Noback, M. A., Bron, S., Paidhungat, M.,Setlow, P. Gene 1998 ;212(2):179-188
pdf for mg0263

1998

Autolysis of Lactococcus lactis is influenced by proteolysis Buist, G., Venema, G.,Kok, J. J Bacteriol 1998 ;180(22):5947-5953
pdf for mg0262

1998

A chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation Sanders, J. W., Leenhouts, K. J., Burghoorn, J., Brands, J. R., Venema, G.,Kok, J. Mol Microbiol 1998 ;27(2):299-310
pdf for mg0260

1998

The signal peptidase II (Isp) gene of Bacillus subtilis Pragai, Z., Tjalsma, H., Bolhuis, A., van Dijl, J. M., Venema, G.,Bron, S. Microbiology 1997 ;143(0):1327-1333
pdf for mg0259

1997

The complete genome sequence of the gram-positive bacterium Bacillus subtilis Kunst, F., Ogasawara, N., Moszer, I., Bron,S., Noback,M., Holsappel,S., etal Nature 1997 ;390(6657):249-256
pdf for mg0258

1997

The chemistry and enzymology of the type I signal peptidases Dalbey, R. E., Lively, M. O., Bron, S.,van Dijl, J. M. Protein Sci 1997 ;6(6):1129-1138

1997

Substrate specificity of hybrid modules from peptide synthetases Elsner, A., Engert, H., Saenger, W., Hamoen, L. W., Venema, G.,Bernhard, F. J Biol Chem 1997 ;272(8):4814-4819
pdf for mg0256

1997

Role of enzymes of homologous recombination in illegitimate plasmid recombination in Bacillus subtilis Meima, R., Haijema, B. J., Dijkstra, H., Haan, G. J., Venema, G.,Bron, S. J Bacteriol 1997 ;179(4):1219-1229
pdf for mg0255

1997

Mutational analysis of a surface area that is critical for the thermal stability of thermolysin-like proteases Veltman, O. R., Vriend, G., Hardy, F., Mansfeld, J., van den Burg, B., Venema, G.,Eijsink, V. G. Eur.J Biochem 1997 ;248(2):433-440

1997

Model building of a thermolysin-like protease by mutagenesis Frigerio, F., Margarit, I., Nogarotto, R., Grandi, G., Vriend, G., Hardy, F., Veltman, O. R., Venema, G.,Eijsink, V. G. Protein Eng. 1997 ;10(3):223-230
pdf for mg0253

1997

Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond Mansfeld, J., Vriend, G., Dijkstra, B. W., Veltman, O. R., van den Burg, B., Venema, G., Ulbrich-Hofmann, R.,Eijsink, V. G. J Biol Chem 1997 ;272(17):11152-11156
pdf for mg0252

1997

Engineering thermolysin-like proteases whose stability is largely independent of calcium Veltman, O. R., Vriend, G., van den Burg, B., Hardy, F., Venema, G.,Eijsink, V. G. FEBS Lett. 1997 ;405(2):241-244
pdf for mg0251

1997

Design of thermolabile bacteriophage repressor mutants by comparative molecular modeling Nauta, A., van den Burg, B., Karsens, H., Venema, G.,Kok, J. Nat Biotechnol 1997 ;15(10):980-983
pdf for mg0250

1997

Cloning and analysis of the pepV dipeptidase gene of Lactococcus lactis MG1363 Hellendoorn, M. A., Franke-Fayard, B. M., Mierau, I., Venema, G.,Kok, J. J Bacteriol 1997 ;179(11):3410-3415
pdf for mg0249

1997

Casein and peptide degradation in lactic acid bacteria Mierau, I., Kunji, E. R., Venema, G.,Kok, J. Biotechnol Genet Eng.Rev. 1997 ;14(0):279-301
pdf for mg0248

1997

Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis Turgay, K., Hamoen, L. W., Venema, G.,Dubnau, D. Genes Dev. 1997 ;11(1):119-128

1997

Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes Tjalsma, H., Noback, M. A., Bron, S., Venema, G., Yamane, K.,van Dijl, J. M. J Biol Chem 1997 ;272(41):25983-25992

1997

Autolysis of Lactococcus lactis caused by induced overproduction of its major autolysin, AcmA Buist, G., Karsens, H., Nauta, A., van Sinderen, D., Venema, G.,Kok, J. Appl Environ.Microbiol 1997 ;63(7):2722-2728
pdf for mg0245

1997

A conserved helicase motif of the AddA subunit of the Bacillus subtilis ATP-dependent nuclease (AddAB) is essential for DNA repair and recombination Kooistra, J., Haijema, B. J., Hesseling-Meinders, A.,Venema, G. Mol Microbiol 1997 ;23(1):137-149

1997

A chloride-inducible gene expression cassette and its use in induced lysis of Lactococcus lactis Sanders, J. W., Venema, G.,Kok, J. Appl Environ.Microbiol 1997 ;63(12):4877-4882
pdf for mg0243

1997

Topology of LcnD, a protein implicated in the transport of bacteriocins from Lactococcus lactis Franke, C. M., Leenhouts, K. J., Haandrikman, A. J., Kok, J., Venema, G.,Venema, K. J Bacteriol 1996 ;178(6):1766-1769
pdf for mg0242

1996

The proteolytic systems of lacatic acid bacteria Kunji, E.R., Mierau, I., Hagting, A., Poolman, B., Konings, W.N. Antonie van Leeuwenhoek 1996 ;70(0):187-221

1996

The genes for secretion and maturation of lactococcins are located on the chromosome of Lactococcus lactis IL1403 Venema, K., Dost, M. H., Beun, P. A., Haandrikman, A. J., Venema, G.,Kok, J. Appl Environ.Microbiol 1996 ;62(5):1689-1692
pdf for mg0240

1996

The expression of a plasmid-specified exported protein causes structural plasmid instability in Bacillus subtilis Cordes, C., Meima, R., Twiest, B., Kazemier, B., Venema, G., van Dijl, J. M.,Bron, S. J Bacteriol 1996 ;178(17):5235-5242
pdf for mg0239

1996

The C terminus of the AddA subunit of the Bacillus subtilis ATP-dependent DNase is required for the ATP-dependent exonuclease activity but not for the helicase activity Haijema, B. J., Venema, G.,Kooistra, J. J Bacteriol 1996 ;178(17):5086-5091
pdf for mg0238

1996

Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage r1t van Sinderen, D., Karsens, H., Kok, J., Terpstra, P., Ruiters, M. H., Venema, G.,Nauta, A. Mol Microbiol 1996 ;19(6):1343-1355

1996

Replacement of the lysine residue in the consensus ATP-binding sequence of the AddA subunit of AddAB drastically affects chromosomal recombination in transformation and transduction of Bacillus subtilis Haijema, B. J., Noback, M. A., Hesseling, A., Kooistra, J., Venema, G.,Meima, R. Mol Microbiol 1996 ;21(5):989-999

1996

Regulated expression of the dinR and recA genes during competence development and SOS induction in Bacillus subtilis Haijema, B. J., van Sinderen, D., Winterling, K., Kooistra, J., Venema, G.,Hamoen, L. W. Mol Microbiol 1996 ;22(1):75-85

1996

Mutational analysis and chemical modification of Cys24 of lactococcin B, a bacteriocin produced by Lactococcus lactis Venema, K., Dost, M. H., Venema, G.,Kok, J. Microbiology 1996 ;142(0):2825-2830

1996

Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk Mierau, I., Kunji, E. R., Leenhouts, K. J., Hellendoorn, M. A., Haandrikman, A. J., Poolman, B., Konings, W. N., Venema, G.,Kok, J. J Bacteriol 1996 ;178(10):2794-2803
pdf for mg0233

1996

Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1 van Veen, H. W., Venema, K., Bolhuis, H., Oussenko, I., Kok, J., Poolman, B., Driessen, A. J.,Konings, W. N. Proc Natl Acad Sci U S A 1996 ;93(20):10668-10672
pdf for mg0232

1996

Molecular analysis of the replication origin of the Lactococcus lactis plasmid pCJ305 Foley, S., Bron, S., Venema, G., Daly, C.,Fitzgerald, G. F. Plasmid 1996 ;36(2):125-141
pdf for mg0231

1996

Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage r1t Nauta, A., van Sinderen, D., Karsens, H., Smit, E., Venema, G.,Kok, J. Mol Microbiol 1996 ;19(6):1331-1341

1996

Inducible gene expression and environmentally regulated genes in lactic acid bacteria Kok, J. Antonie Van Leeuwenhoek 1996 ;70(2):129-145

1996

Identification and characterization of a novel type of replication terminator with bidirectional activity on the Bacillus subtilis theta plasmid pLS20 Meijer, W. J., Smith, M., Wake, R. G., de Boer, A. L., Venema, G.,Bron, S. Mol Microbiol 1996 ;19(6):1295-1306
pdf for mg0228

1996

Fate of peptides in peptidase mutants of Lactococcus lactis Kunji, E. R., Mierau, I., Poolman, B., Konings, W. N., Venema, G.,Kok, J. Mol Microbiol 1996 ;21(1):123-131

1996

Effects of lysine-to-glycine mutations in the ATP-binding consensus sequences in the AddA and AddB subunits on the Bacillus subtilis AddAB enzyme activities Haijema, B. J., Meima, R., Kooistra, J.,Venema, G. J Bacteriol 1996 ;178(17):5130-5137
pdf for mg0226

1996

Cloning of heterologous genes specifying detrimental proteins on pUC-derived plasmids in Escherichia coli M?ller, J. P., van Dijl, J. M., Venema, G.,Bron, S. Mol Gen.Genet 1996 ;252(1):207-211

1996

Bacillus subtilis can modulate its capacity and specificity for protein secretion through temporally controlled expression of the sipS gene for signal peptidase I Bolhuis, A., Sorokin, A., Azevedo, V., Ehrlich, S. D., Braun, P. G., de Jong, A., Venema, G., Bron, S.,van Dijl, J. M. Mol Microbiol 1996 ;22(4):605-618
pdf for mg0224

1996

Analysis of structural determinants of the stability of thermolysin-like proteases by molecular modelling and site-directed mutagenesis Veltman, O. R., Vriend, G., Middelhoven, P. J., van den Burg, B., Venema, G.,Eijsink, V. G. Protein Eng. 1996 ;9(12):1181-1189

1996

A positive selection vector for the analysis of structural plasmid instability in Bacillus subtilis Meima, R., Venema, G.,Bron, S. Plasmid 1996 ;35(1):14-30
pdf for mg0222

1996

A general system for generating unlabelled gene replacements in bacterial chromosomes Leenhouts, K. J., Buist, G., Bolhuis, A., ten Berge, A. M., Kiel, J. A., Mierau, I., Dabrowska, M., Venema, G.,Kok, J. Mol Gen.Genet 1996 ;253(1):217-224
pdf for mg0221

1996

A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome Noback, M. A., Terpstra, P., Holsappel, S., Venema, G.,Bron, S. Microbiology 1996 ;142(0):3021-3026
pdf for mg0220

1996

Use of continuous culture for the selection of plasmids with improved segregational stability Seegers, J. F., Franke, C. M., Kiewiet, R., Venema, G.,Bron, S. Plasmid 1995 ;33(1):71-77
pdf for mg0219

1995

The endogenous Bacillus subtilis (natto) plasmids pTA1015 and pTA1040 contain signal peptidase-encoding genes: identification of a new structural module on cryptic plasmids Meijer, W. J., de Jong, A., Wisman, G. B., Tjalsma, H., Venema, G., Bron, S.,van Dijl, J. M. Mol Microbiol 1995 ;17(4):621-631

1995

Structural determinants of the stability of thermolysin-like proteinases Eijsink, V. G., Veltman, O. R., Aukema, W., Vriend, G.,Venema, G. Nat Struct.Biol 1995 ;2(5):374-379

1995

Structural and functional analysis of the single-strand origin of replication from the lactococcal plasmid pWV01 Seegers, J. F., Zhao, A. C., Meijer, W. J., Khan, S. A., Venema, G.,Bron, S. Mol Gen.Genet 1995 ;249(1):43-50
pdf for mg0216

1995

Stress response in Lactococcus lactis: cloning, expression analysis, and mutation of the lactococcal superoxide dismutase gene Sanders, J. W., Leenhouts, K. J., Haandrikman, A. J., Venema, G.,Kok, J. J Bacteriol 1995 ;177(18):5254-5260

1995

Overproduction of the ATP-dependent nuclease AddAB improves the structural stability of a model plasmid system in Bacillus subtilis Meima, R., Haijema, B. J., Venema, G.,Bron, S. Mol Gen.Genet 1995 ;248(4):391-398
pdf for mg0214

1995

Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation Buist, G., Kok, J., Leenhouts, K. J., Dabrowska, M., Venema, G.,Haandrikman, A. J. J Bacteriol 1995 ;177(6):1554-1563

1995

Lactococcal bacteriocins: mode of action and immunity Venema, K., Venema, G.,Kok, J. Trends Microbiol 1995 ;3(8):299-304

1995

Identification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and functional similarities with LexA-like proteases van Dijl, J. M., de Jong, A., Venema, G.,Bron, S. J Biol Chem 1995 ;270(8):3611-3618
pdf for mg0211

1995

Genetics of peptide degradation in Lactococcus: gene cloning, construction and analysis of peptidase negative mutants Mierau, I., Haandrikman, A. J., Leenhouts, K. J., Tan, P. S., Konings, W. N., Venema, G.,Kok, J. Dev.Biol Stand. 1995 ;85(0):503-507
pdf for mg0210

1995

Genetic modification and the proteolytic system of lactococci Venema, G., Haandrikman, A. J.,Kok, J. Dev.Biol Stand. 1995 ;85(0):495-502
pdf for mg0209

1995

Generation of the glycyl radical of the anaerobic Escherichia coli ribonucleotide reductase requires a specific activating enzyme. Sun, X.., Eliasson, R., Pontis, E., Andersson, J., Buist, G., Sjoberg, B.M., Reichard, P. J Biol Chem 1995 ;270(0):2443-2446

1995

Functional analysis of the pediocin operon of Pediococcus acidilactici PAC1.0: PedB is the immunity protein and PedD is the precursor processing enzyme Venema, K., Kok, J., Marugg, J. D., Toonen, M. Y., Ledeboer, A. M., Venema, G.,Chikindas, M. L. Mol Microbiol 1995 ;17(3):515-522

1995

Expression of the ATP-dependent deoxyribonuclease of Bacillus subtilis is under competence-mediated control Haijema, B. J., Hamoen, L. W., Kooistra, J., Venema, G.,van Sinderen, D. Mol Microbiol 1995 ;15(2):203-211

1995

Expression of lactococcin A and pediocin PA-1 in heterologous hosts Chikindas, M. L., Venema, K., Ledeboer, A. M., Venema, G.,Kok, J. Lett.Appl Microbiol 1995 ;21(3):183-189
pdf for mg0205

1995

Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in Lactococcus lactis Meijer, W. J., van der Lelie, D., Venema, G.,Bron, S. Plasmid 1995 ;33(2):91-99
pdf for mg0204

1995

Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in different Bacillus subtilis strains Meijer, W. J., van der Lelie, D., Venema, G.,Bron, S. Plasmid 1995 ;33(2):79-89
pdf for mg0203

1995

Differential expression of two closely related deoxyribonuclease genes, nucA and nucB, in Bacillus subtilis van Sinderen, D., Kiewiet, R.,Venema, G. Mol Microbiol 1995 ;15(2):213-223

1995

comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis van Sinderen, D., Luttinger, A., Kong, L., Dubnau, D., Venema, G.,Hamoen, L. W. Mol Microbiol 1995 ;15(3):455-462

1995

Cloning and molecular analysis of the dihydrofolate reductase gene from Lactococcus lactis Leszczynska, K., Bolhuis, A., Leenhouts, K. J., Venema, G.,Ceglowski, P. Appl Environ.Microbiol 1995 ;61(2):561-566

1995

Chitinase B from Serratia marcescens BJL200 is exported to the periplasm without processing Brurberg, M. B., Eijsink, V. G., Haandrikman, A. J., Venema, G.,Nes, I. F. Microbiology 1995 ;141(0):123-131

1995

Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon Meijer, W. J., de Boer, A. J., van Tongeren, S., Venema, G.,Bron, S. Nucleic Acids Res 1995 ;23(16):3214-3223
pdf for mg0198

1995

Characterization of single strand origins of cryptic rolling-circle plasmids from Bacillus subtilis Meijer, W. J., Venema, G.,Bron, S. Nucleic Acids Res 1995 ;23(4):612-619
pdf for mg0197

1995

Analysis of lactococcin secretion and immunity in Lactococcus lactis Kok, J., Venema, K.,Venema, G. Dev.Biol Stand. 1995 ;85(0):653-659
pdf for mg0196

1995

A system to generate chromosomal mutations in Lactococcus lactis which allows fast analysis of targeted genes Law, J., Buist, G., Haandrikman, A. J., Kok, J., Venema, G.,Leenhouts, K. J. J Bacteriol 1995 ;177(24):7011-7018

1995

A small gene, designated comS, located within the coding region of the fourth amino acid-activation domain of srfA, is required for competence development in Bacillus subtilis Hamoen, L. W., Eshuis, H., Jongbloed, J. D., Venema, G.,van Sinderen, D. Mol Microbiol 1995 ;15(1):55-63

1995

A general method for the consecutive integration of single copies of a heterologous gene at multiple locations in the Bacillus subtilis chromosome by replacement recombination Kiel, J. A., ten Berge, A. M., Borger, P.,Venema, G. Appl Environ.Microbiol 1995 ;61(12):4244-4250

1995

Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant Mierau, I., Haandrikman, A. J., Velterop, O., Tan, P. S., Leenhouts, K. J., Konings, W. N., Venema, G.,Kok, J. J Bacteriol 1994 ;176(10):2854-2861

1994

The majority of lactococcal plasmids carry a highly related replicon Seegers, J. F., Bron, S., Franke, C. M., Venema, G.,Kiewiet, R. Microbiology 1994 ;140(0):1291-1300

1994

The effect of engineering surface loops on the thermal stability of Bacillus subtilis neutral protease Hardy, F., Vriend, G., van der Vossen, J. M. B. M., Frigerio, F., Grandi, G., Venema, G.,Eijsink, V. G. Protein Eng. 1994 ;7(3):425-430

1994

Protein stabilization by hydrophobic interactions at the surface van den Burg, B., Dijkstra, B. W., Vriend, G., van der Vossen, J. M. B. M., Venema, G.,Eijsink, V. G. Eur.J Biochem 1994 ;220(3):981-985

1994

Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis van Sinderen, D., ten Berge, A. M., Hayema, B. J., Hamoen, L. W.,Venema, G. Mol Microbiol 1994 ;11(4):695-703

1994

Mode of action of LciA, the lactococcin A immunity protein Venema, K., Haverkort, R. E., Abee, T., Haandrikman, A. J., Leenhouts, K. J., de Leij, L., Venema, G.,Kok, J. Mol Microbiol 1994 ;14(3):521-532

1994

Identification of TlpC, a novel 62 kDa MCP-like protein from Bacillus subtilis Hanlon, D. W., Rosario, M. M., Ordal, G. W., Venema, G.,van Sinderen, D. Microbiology 1994 ;140(0):1847-1854

1994

Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G. Mol Microbiol 1994 ;11(1):203-218

1994

Expression of a chitinase gene from Serratia marcescens in Lactococcus lactis and Lactobacillus plantarum Brurberg, M. B., Haandrikman, A. J., Leenhouts, K. J., Venema, G.,Nes, I. F. Appl Microbiol Biotechnol 1994 ;42(1):108-115

1994

Design, synthesis, and preliminary characterization of tyrosine-containing polyarylates: new biomaterials for medical applications Fiordeliso, J., Bron, S.,Kohn, J. J Biomater.Sci Polym.Ed. 1994 ;5(6):497-510

1994

comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis van Sinderen, D., Venema, G. J Bacteriol 1994 ;176(18):5762-5770

1994

Two putative insertion sequences flank a truncated glycogen branching enzyme gene in the thermophile Bacillus stearothermophilus CU21 Kiel, J. A., Boels, J. M., ten Berge, A. M.,Venema, G. DNA Seq. 1993 ;4(1):1-9
pdf for mg0181

1993

Theta replication of the lactococcal plasmid pWVO2 Kiewiet, R., Bron, S., de Jonge, K., Venema, G.,Seegers, J. F. Mol Microbiol 1993 ;10(2):319-327
pdf for mg0180

1993

The Bacillus subtilis addAB genes are fully functional in Escherichia coli Kooistra, J., Haijema, B. J.,Venema, G. Mol Microbiol 1993 ;7(6):915-923

1993

Stabilization of Bacillus stearothermophilus neutral protease by introduction of prolines Hardy, F., Vriend, G., Veltman, O. R., van der Vossen, J. M. B. M., Venema, G.,Eijsink, V. G. FEBS Lett. 1993 ;317(1):89-92

1993

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis Cosmina, P., Rodriguez, F., de Ferra, F., Grandi, G., Perego, M., Venema, G.,van Sinderen, D. Mol Microbiol 1993 ;8(5):821-831

1993

Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells Chikindas, M. L., Garcia-Garcera, M. J., Driessen, A. J., Ledeboer, A. M., Nissen-Meyer, J., Nes, I. F., Abee, T., Konings, W. N.,Venema, G. Appl Environ.Microbiol 1993 ;59(11):3577-3584

1993

Introduction of disulfide bonds into Bacillus subtilis neutral protease van den Burg, B., Dijkstra, B. W., van der Vossen, J. M. B. M., Stulp, B. K., Eijsink, V. G.,Venema, G. Protein Eng. 1993 ;6(5):521-527

1993

In vitro assay for the Bacillus subtilis signal peptidase SipS: systems for efficient in vitro transcription-translation and processing of precursors of secreted proteins Vehmaanpera, J., Gorner, A., Venema, G., Bron, S.,van Dijl, J. M. FEMS Microbiol Lett. 1993 ;114(2):207-214

1993

Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis Tynkkynen, S., Buist, G., Kunji, E. R., Kok, J., Poolman, B., Venema, G.,Haandrikman, A. J. J Bacteriol 1993 ;175(23):7523-7532

1993

Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian enkephalinase Mierau, I., Tan, P. S., Haandrikman, A. J., Mayo, B., Kok, J., Leenhouts, K. J., Konings, W. N.,Venema, G. J Bacteriol 1993 ;175(7):2087-2096

1993

Characterization of the srfA locus of Bacillus subtilis: only the valine-activating domain of srfA is involved in the establishment of genetic competence van Sinderen, D., Galli, G., Cosmina, P., de Ferra, F., Withoff, S., Venema, G.,Grandi, G. Mol Microbiol 1993 ;8(5):833-841

1993

The integrated state of the rolling-circle plasmid pTB913 in the composite Bacillus plasmid pTB19 Oskam, L., Hillenga, D. J., Venema, G.,Bron, S. Mol Gen.Genet 1992 ;233(3):462-468
pdf for mg0170

1992

The glgB gene from the thermophile Bacillus caldolyticus encodes a thermolabile branching enzyme Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G. DNA Seq. 1992 ;3(4):221-232

1992

The effect of cavity-filling mutations on the thermostability of Bacillus stearothermophilus neutral protease Eijsink, V. G., Dijkstra, B. W., Vriend, G., van der Zee, J. R., Veltman, O. R., van der Vossen, J. M. B. M., van den Burg, B., Kempe, S.,Venema, G. Protein Eng. 1992 ;5(5):421-426
pdf for mg0168

1992

Signal peptidase I of Bacillus subtilis: patterns of conserved amino acids in prokaryotic and eukaryotic type I signal peptidases van Dijl, J. M., de Jong, A., Vehmaanpera, J., Venema, G.,Bron, S. EMBO J 1992 ;11(8):2819-2828

1992

Protein export elements from Lactococcus lactis Perez-Martinez, G., Kok, J., Venema, G., van Dijl, J. M., Smith, H.,Bron, S. Mol Gen.Genet 1992 ;234(3):401-411
pdf for mg0166

1992

Plasmid pTB913 derivatives are segregationally stable in Bacillus subtilis at elevated temperatures Oskam, L., Venema, G.,Bron, S. Plasmid 1992 ;28(1):70-79
pdf for mg0165

1992

Plasmid maintenance in Bacillus stearothermophilus is strain-dependent Oskam, L., Venema, G.,Bron, S. FEMS Microbiol Lett. 1992 ;72(3):203-208
pdf for mg0164

1992

Nucleotide sequence of the Synechococcus sp. PCC7942 hemE gene encoding the homologue of mammalian uroporphyrinogen decarboxylase Kiel, J. A., ten Berge, A. M.,Venema, G. DNA Seq. 1992 ;2(6):415-418

1992

Molecular analyses of the lactococcin A gene cluster from Lactococcus lactis subsp. lactis biovar diacetylactis WM4 Stoddard, G. W., Petzel, J. P., van Belkum, M. J., Kok, J.,McKay, L. L. Appl Environ.Microbiol 1992 ;58(6):1952-1961

1992

Lysozyme expression in Lactococcus lactis van de Guchte, M., van der Wal, F. J., Kok, J.,Venema, G. Appl Microbiol Biotechnol 1992 ;37(2):216-224

1992

Localization and accessibility of antigenic sites of the extracellular serine proteinase of Lactococcus lactis Laan, H., Kok, J., Haandrikman, A. J., Venema, G.,Konings, W. N. Eur.J Biochem 1992 ;204(2):815-820

1992

Introduction of a stabilizing 10 residue beta-hairpin in Bacillus subtilis neutral protease Eijsink, V. G., Vriend, G., van den Burg, B., van der Zee, J. R., Veltman, O. R., Stulp, B. K.,Venema, G. Protein Eng. 1992 ;5(2):157-163

1992

Increasing the thermostability of the neutral proteinase of Bacillus stearothermophilus by improvement of internal hydrogen-bonding Eijsink, V. G., Vriend, G., van der Zee, J. R., van den Burg, B.,Venema, G. Biochem J 1992 ;285(0):625-628

1992

Increasing the thermostability of a neutral protease by replacing positively charged amino acids in the N-terminal turn of alpha-helices Eijsink, V. G., Vriend, G., van den Burg, B., van der Zee, J. R.,Venema, G. Protein Eng. 1992 ;5(2):165-170

1992

Gene expression in Lactococcus lactis van de Guchte, M., Kok, J.,Venema, G. FEMS Microbiol Rev. 1992 ;8(2):73-92
pdf for mg0156

1992

Effects of changing the interaction between subdomains on the thermostability of Bacillus neutral proteases Eijsink, V. G., Vriend, G., van der Vossen, J. M. B. M., Hazes, B., van den Burg, B.,Venema, G. Proteins 1992 ;14(2):224-236

1992

Cloning, sequencing, and expression in Escherichia coli of lcnB, a third bacteriocin determinant from the lactococcal bacteriocin plasmid p9B4-6 van Belkum, M. J., Kok, J.,Venema, G. Appl Environ.Microbiol 1992 ;58(2):572-577

1992

Characterization of transcription initiation and termination signals of the proteinase genes of Lactococcus lactis Wg2 and enhancement of proteolysis in L. lactis van der Vossen, J. M. B. M., Kodde, J., Haandrikman, A. J., Venema, G.,Kok, J. Appl Environ.Microbiol 1992 ;58(9):3142-3149

1992

Thermostability of Bacillus subtilis neutral protease Eijsink, V. G., van den Burg, B., Vriend, G., Berendsen, H. J.,Venema, G. Biochem Int. 1991 ;24(3):517-525

1991

The large Bacillus plasmid pTB19 contains two integrated rolling-circle plasmids carrying mobilization functions Oskam, L., Hillenga, D. J., Venema, G.,Bron, S. Plasmid 1991 ;26(1):30-39
pdf for mg0151

1991

The bacteriocin lactococcin A specifically increases permeability of lactococcal cytoplasmic membranes in a voltage-independent, protein-mediated manner van Belkum, M. J., Kok, J., Venema, G., Holo, H., Nes, I. F., Konings, W. N.,Abee, T. J Bacteriol 1991 ;173(24):7934-7941
pdf for mg0150

1991

Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule Vriend, G., Berendsen, H. J., van der Zee, J. R., van den Burg, B., Venema, G.,Eijsink, V. G. Protein Eng. 1991 ;4(8):941-945

1991

Signal peptidase I overproduction results in increased efficiencies of export and maturation of hybrid secretory proteins in Escherichia coli van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G. Mol Gen.Genet 1991 ;227(1):40-48
pdf for mg0148

1991

Replacement recombination in Lactococcus lactis Leenhouts, K. J., Kok, J.,Venema, G. J Bacteriol 1991 ;173(15):4794-4798

1991

Proteinase genes of cheese starter cultures Kok, J. Biochem Soc.Trans. 1991 ;19(3):670-674
pdf for mg0146

1991

Processing of the lactococcal extracellular serine proteinase Haandrikman, A. J., Meesters, R., Laan, H., Konings, W. N., Kok, J.,Venema, G. Appl Environ.Microbiol 1991 ;57(7):1899-1904

1991

Plasmid instability and molecular cloning in Bacillus subtilis Bron, S., Meijer, W., Holsappel, S.,Haima, P. Res Microbiol 1991 ;142(7):875-883
pdf for mg0144

1991

Plasmid deletion formation between short direct repeats in Bacillus subtilis is stimulated by single-stranded rolling-circle replication intermediates Bron, S., Holsappel, S., Venema, G.,Peeters, B. P. Mol Gen.Genet 1991 ;226(1):88-96

1991

Organization and nucleotide sequences of two lactococcal bacteriocin operons van Belkum, M. J., Hayema, B. J., Jeeninga, R. E., Kok, J.,Venema, G. Appl Environ.Microbiol 1991 ;57(2):492-498

1991

Nucleotide sequence and characterization of the broad-host-range lactococcal plasmid pWVO1 Leenhouts, K. J., Tolner, B., Bron, S., Kok, J., Venema, G.,Seegers, J. F. Plasmid 1991 ;26(1):55-66
pdf for mg0141

1991

Non-functional expression of Escherichia coli signal peptidase I in Bacillus subtilis van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G. J Gen.Microbiol 1991 ;137(0):2073-2083

1991

Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris Mayo, B., Kok, J., Venema, K., Bockelmann, W., Teuber, M., Reinke, H.,Venema, G. Appl Environ.Microbiol 1991 ;57(1):38-44

1991

Molecular cloning and nucleotide sequence of the glycogen branching enzyme gene (glgB) from Bacillus stearothermophilus and expression in Escherichia coli and Bacillus subtilis Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G. Mol Gen.Genet 1991 ;230(1):136-144

1991

Lactococcal proteinase maturation protein PrtM is a lipoprotein Haandrikman, A. J., Kok, J.,Venema, G. J Bacteriol 1991 ;173(14):4517-4525

1991

Lactococcal plasmid pWV01 as an integration vector for lactococci Leenhouts, K. J., Kok, J.,Venema, G. Appl Environ.Microbiol 1991 ;57(9):2562-2567

1991

Lack of specific hybridization between the lep genes of Salmonella typhimurium and Bacillus licheniformis van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G. FEMS Microbiol Lett. 1991 ;65(3):345-351

1991

Isolation, sequence and expression in Escherichia coli, Bacillus subtilis and Lactococcus lactis of the DNase (streptodornase)-encoding gene from Streptococcus equisimilis H46A Wolinowska, R., Ceglowski, P., Kok, J.,Venema, G. Gene 1991 ;106(1):115-119

1991

Improving the thermostability of the neutral protease of Bacillus stearothermophilus by replacing a buried asparagine by leucine Eijsink, V. G., van der Zee, J. R., van den Burg, B., Vriend, G.,Venema, G. FEBS Lett. 1991 ;282(1):13-16

1991

Identification of a new genetic determinant for cell aggregation associated with lactose plasmid transfer in Lactococcus lactis van der Lelie, D., Chavarri, F., Venema, G.,Gasson, M. J. Appl Environ.Microbiol 1991 ;57(1):201-206

1991

High performance affinity chromatography of Bacillus neutral proteases Eijsink, V. G., van den Burg, B.,Venema, G. Biotechnol Appl Biochem 1991 ;14(3):275-283

1991

Engineering of the Lactococcus lactis serine proteinase by construction of hybrid enzymes Vos, P., Boerrigter, I. J., Buist, G., Haandrikman, A. J., Nijhuis, M., de Reuver, M. B., Siezen, R. J., Venema, G., de Vos, W. M.,Kok, J. Protein Eng. 1991 ;4(4):479-484
pdf for mg0130

1991

Distance-dependent translational coupling and interference in Lactococcus lactis van de Guchte, M., Kok, J.,Venema, G. Mol Gen.Genet 1991 ;227(1):65-71

1991

Cloning, sequencing, and expression of Bacillus subtilis genes involved in ATP-dependent nuclease synthesis Kooistra, J., Venema, G. J Bacteriol 1991 ;173(12):3644-3655

1991

Chromosomal stabilization of the proteinase genes in Lactococcus lactis Leenhouts, K. J., Gietema, J., Kok, J.,Venema, G. Appl Environ.Microbiol 1991 ;57(9):2568-2575

1991

A possible contribution of mRNA secondary structure to translation initiation efficiency in Lactococcus lactis van de Guchte, M., van der Lende, T., Kok, J.,Venema, G. FEMS Microbiol Lett. 1991 ;65(2):201-208

1991

A highly thermostable neutral protease from Bacillus caldolyticus: cloning and expression of the gene in Bacillus subtilis and characterization of the gene product van den Burg, B., Enequist, H. G., van der Haar, M. E., Eijsink, V. G., Stulp, B. K.,Venema, G. J Bacteriol 1991 ;173(13):4107-4115

1991

Translational coupling in a penP-lacZ gene fusion in Bacillus subtilis and Escherichia coli: use of AUA as a restart codon Peijnenburg, A. A. C. M., Venema, G.,Bron, S. Mol Gen.Genet 1990 ;221(2):267-272
pdf for mg0124

1990

Nucleotide sequence of the Synechococcus sp. PCC7942 branching enzyme gene (glgB): expression in Bacillus subtilis Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G. Gene 1990 ;89(1):77-84

1990

Novel plasmid marker rescue transformation system for molecular cloning in Bacillus subtilis enabling direct selection of recombinants Haima, P., Bron, S.,Venema, G. Mol Gen.Genet 1990 ;223(2):185-191
pdf for mg0122

1990

Molecular cloning of the Salmonella typhimurium lep gene in Escherichia coli van Dijl, J. M., van den Bergh, R., Reversma, T., Smith, H., Bron, S.,Venema, G. Mol Gen.Genet 1990 ;223(2):233-240

1990

Isolation and characterization of comL, a transcription unit involved in competence development of Bacillus subtilis van Sinderen, D., Withoff, S., Boels, H.,Venema, G. Mol Gen.Genet 1990 ;224(3):396-404

1990

Insertion elements on lactococcal proteinase plasmids Haandrikman, A. J., van Leeuwen, C., Kok, J., Vos, P., de Vos, W. M.,Venema, G. Appl Environ.Microbiol 1990 ;56(6):1890-1896

1990

Identification of autodigestion target sites in Bacillus subtilis neutral proteinase van den Burg, B., Eijsink, V. G., Stulp, B. K.,Venema, G. Biochem J 1990 ;272(1):93-97

1990

Heterologous gene expression in Lactococcus lactis subsp. lactis: synthesis, secretion, and processing of the Bacillus subtilis neutral protease van de Guchte, M., Kodde, J., van der Vossen, J. M. B. M., Kok, J.,Venema, G. Appl Environ.Microbiol 1990 ;56(9):2606-2611

1990

Genetics of the proteolytic system of lactic acid bacteria Kok, J. FEMS Microbiol Rev. 1990 ;7(1):15-42

1990

Contribution of the C-terminal amino acid to the stability of Bacillus subtilis neutral protease Eijsink, V. G., Vriend, G., van den Burg, B., Venema, G.,Stulp, B. K. Protein Eng. 1990 ;4(1):99-104
pdf for mg0115

1990

Conjugal mobilization of streptococcal plasmid pMV158 between strains of Lactococcus lactis subsp. lactis van der Lelie, D., Wosten, H. A., Bron, S., Oskam, L.,Venema, G. J Bacteriol 1990 ;172(1):47-52
pdf for mg0114

1990

Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences Peeters, B. P., Bron, S.,Ehrlich, S. D. EMBO J 1990 ;9(0):3023-9

1990

An improved beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis Haima, P., van Sinderen, D., Bron, S.,Venema, G. Gene 1990 ;93(1):41-47
pdf for mg0112

1990

Similarity of minus origins of replication and flanking open reading frames of plasmids pUB110, pTB913 and pMV158 van der Lelie, D., Bron, S., Venema, G.,Oskam, L. Nucleic Acids Res 1989 ;17(18):7283-7294

1989

Plasmid deletion formation in recE4 and addB72 mutants of Bacillus subtilis Peijnenburg, A. A. C. M., Breed, P. V., Bron, S.,Venema, G. Plasmid 1989 ;21(3):205-215
pdf for mg0110

1989

One-step affinity purification of Bacillus neutral proteases using bacitracin-silica van den Burg, B., Eijsink, V. G., Stulp, B. K.,Venema, G. J Biochem Biophys.Methods 1989 ;18(3):209-219

1989

Identification of a gene required for maturation of an extracellular lactococcal serine proteinase Haandrikman, A. J., Kok, J., Laan, H., Soemitro, S., Ledeboer, A. M., Konings, W. N.,Venema, G. J Bacteriol 1989 ;171(5):2789-2794

1989

Construction of a lactococcal expression vector: expression of hen egg white lysozyme in Lactococcus lactis subsp. lactis van de Guchte, M., van der Vossen, J. M. B. M., Kok, J.,Venema, G. Appl Environ.Microbiol 1989 ;55(1):224-228
pdf for mg0107

1989

Cloning of two bacteriocin genes from a lactococcal bacteriocin plasmid van Belkum, M. J., Hayema, B. J., Geis, A., Kok, J.,Venema, G. Appl Environ.Microbiol 1989 ;55(5):1187-1191

1989

Cloning and expression of the branching enzyme gene (glgB) from the cyanobacterium Synechococcus sp. PCC7942 in Escherichia coli Kiel, J. A., Elgersma, H. S., Beldman, G., Vossen, J. P.,Venema, G. Gene 1989 ;78(1):9-17

1989

Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis Leenhouts, K. J., Kok, J.,Venema, G. Appl Environ.Microbiol 1989 ;55(2):394-400

1989

Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences Brunier, D., Peeters, B. P., Bron, S.,Ehrlich, S. D. EMBO J 1989 ;8(10):3127-3133
pdf for mg0103

1989

Transformation in Bacillus subtilis: involvement of the 17-kilodalton DNA-entry nuclease and the competence-specific 18-kilodalton protein Vosman, B., Kuiken, G., Kooistra, J.,Venema, G. J Bacteriol 1988 ;170(8):3703-3710

1988

Synthesis and processing of Escherichia coli TEM-beta-lactamase and Bacillus licheniformis alpha-amylase in E. coli: the role of signal peptidase I van Dijl, J. M., Smith, H., Bron, S.,Venema, G. Mol Gen.Genet 1988 ;214(1):55-61
pdf for mg0101

1988

Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats Peeters, B. P., de Boer, J. H., Bron, S.,Venema, G. Mol Gen.Genet 1988 ;212(3):450-458

1988

Restriction and modification in Bacillus subtilis Marburg 168: target sites and effects on plasmid transformation Bron, S., Janniere, L.,Ehrlich, S. D. Mol Gen.Genet 1988 ;211(1):186-189
pdf for mg0099

1988

Plasmid deletion formation in Bacillus subtilis Peijnenburg, A. A. C. M., Bron, S.,Venema, G. Plasmid 1988 ;20(1):23-32
pdf for mg0098

1988

Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2 Kok, J., Leenhouts, K. J., Haandrikman, A. J., Ledeboer, A. M.,Venema, G. Appl Environ.Microbiol 1988 ;54(1):231-238
pdf for mg0097

1988

Instability of recombinant pUB110 plasmids in Bacillus subtilis: plasmid-encoded stability function and effects of DNA inserts Bron, S., Luxen, E.,Swart, P. Plasmid 1988 ;19(3):231-241
pdf for mg0096

1988

Genetics of proteinases of lactic acid bacteria Kok, J., Venema, G. Biochimie 1988 ;70(4):475-488

1988

Effect of plasmid incompatibility on DNA transfer to Streptococcus cremoris van der Lelie, D., van der Vossen, J.M.B.M., Venema, G. Appl Environ.Microbiol 1988 ;54(0):865-871

1988

Deletion analysis of the proteinase gene of Streptococcus cremoris Wg2 Kok, J., Hill, D., Haandrikman, A. J., de Reuver, M. J., Laan, H.,Venema, G. Appl Environ.Microbiol 1988 ;54(1):239-244
pdf for mg0093

1988

Cloning and characterization of the tetracycline resistance determinant of and several promoters from within the conjugative transposon Tn919 Hill, C., Venema, G., Daly, C.,Fitzgerald, G. F. Appl Environ.Microbiol 1988 ;54(5):1230-1236

1988

Cloning and characterization of a Bacillus subtilis transcription unit involved in ATP-dependent DNase synthesis Kooistra, J., Vosman, B.,Venema, G. J Bacteriol 1988 ;170(10):4791-4797

1988

Characterization of signal-sequence-coding regions selected from the Bacillus subtilis chromosome Smith, H., de Jong, A., Bron, S.,Venema, G. Gene 1988 ;70(2):351-361

1988

The effect of restriction on shotgun cloning and plasmid stability in Bacillus subtilis Marburg Haima, P., Bron, S.,Venema, G. Mol Gen.Genet 1987 ;209(2):335-342

1987

The cell wall-associated proteases of Streptococcus cremoris Wg2. Hugenholtz, J., van Sinderen, J., Kok, J., Konings, W.N. Appl Environ.Microbiol 1987 ;53(0):853-859

1987

Structural plasmid instability in recombination- and repair-deficient strains of Bacillus subtilis Peijnenburg, A. A. C. M., Bron, S.,Venema, G. Plasmid 1987 ;17(2):167-170
pdf for mg0087

1987

Stability function in the Bacillus subtilis plasmid pTA 1060 Bron, S., Bosma, P., van Belkum, M. J.,Luxen, E. Plasmid 1987 ;18(1):8-15

1987

Isolation and characterization of Streptococcus cremoris Wg2-specific promoters van der Vossen, J. M. B. M., van der Lelie, D.,Venema, G. Appl Environ.Microbiol 1987 ;53(10):2452-2457
pdf for mg0085

1987

Improving starter cultures. Venema, G., Kok. J. Trends in Biotechnology. 1987 ;5(0):144-149

1987

Construction and use of signal sequence selection vectors in Escherichia coli and Bacillus subtilis Smith, H., Bron, S., van Ee, J.,Venema, G. J Bacteriol 1987 ;169(7):3321-3328
pdf for mg0082

1987

Cloning in Escherichia coli of the gene specifying the DNA-entry nuclease of Bacillus subtilis Vosman, B., Kooistra, J., Olijve, J.,Venema, G. Gene 1987 ;52(2):175-183

1987

Bacillus subtilis generates a major specific deletion in pAM beta 1 van der Lelie, D., Venema, G. Appl Environ.Microbiol 1987 ;53(10):2458-2463

1987

A general method for the construction of Escherichia coli mutants by homologous recombination and plasmid segregation Kiel, J. A., Vossen, J. P.,Venema, G. Mol Gen.Genet 1987 ;207(2):294-301

1987

Integration of vector-containing Bacillus subtilis chromosomal DNA by a Campbell-like mechanism Vosman, B., Kooistra, J., Olijve, J.,Venema, G. Mol Gen.Genet 1986 ;204(3):524-531

1986

Transformation in Bacillus subtilis: further characterization of a 75,000-dalton protein complex involved in binding and entry of donor DNA Smith, H., Wiersma, K., Venema, G.,Bron, S. J Bacteriol 1985 ;164(1):201-206

1985

Segregational instability of pUB110-derived recombinant plasmids in Bacillus subtilis Bron, S., Luxen, E. Plasmid 1985 ;14(3):235-244

1985

Effect of concentration on the subsequent fate of plasmid DNA in human fibroblasts Mooibroek, H., Arnberg, A. C., de Jong, B.,Venema, G. Mol Gen.Genet 1985 ;199(1):82-88

1985

Construction of cloning, promoter-screening, and terminator-screening shuttle vectors for Bacillus subtilis and Streptococcus lactis van der Vossen, J. M. B. M., Kok, J.,Venema, G. Appl Environ.Microbiol 1985 ;50(2):540-542
pdf for mg0074

1985

Cloning and expression of a Streptococcus cremoris proteinase in Bacillus subtilis and Streptococcus lactis Kok, J., van Dijl, J. M., van der Vossen, J. M. B. M.,Venema, G. Appl Environ.Microbiol 1985 ;50(1):94-101
pdf for mg0073

1985

Transformation in Bacillus subtilis: a 75,000-dalton protein complex is involved in binding and entry of donor DNA Smith, H., Wiersma, K., Venema, G.,Bron, S. J Bacteriol 1984 ;157(3):733-738

1984

Restriction of hemimethylated DNA by the Bacillus subtilis R system Bron, S., Luxen, E.,Venema, G. Mol Gen.Genet 1984 ;195(1):370-373
pdf for mg0071

1984

Repair of UV damage in plasmid DNA by human fibroblasts Mooibroek, H., de Jong, B.,Venema, G. Mol Gen.Genet 1984 ;195(1):175-179

1984

Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis: further characterization of unstable association between donor and recipient DNA and the involvement of the cellular membrane te Riele, H. P., Venema, G. Mol Gen.Genet 1984 ;195(1):200-208

1984

Isolation and characterization of Bacillus subtilis mutants altered in competence Fani, R., Mastromei, G., Polsinelli, M.,Venema, G. J Bacteriol 1984 ;157(1):152-157

1984

Involvement of single-strand breaks in complex formation between single-stranded DNA and nucleoids of Bacillus subtilis van Randen, J., Wiersma, K.,Venema, G. Mol Gen.Genet 1984 ;193(3):500-506

1984

Heterospecific transformation in Bacillus subtilis: protein composition of a membrane-DNA complex containing unstable heterologous donor-recipient complex te Riele, H. P., Venema, G. Mol Gen.Genet 1984 ;197(3):478-485

1984

Genetic manipulation of the restricted facultative methylotroph Hyphomicrobium X by the R-plasmid-mediated introduction of the Escherichia coli pdh genes Dijkhuizen, L., Harder, W., de Boer, L., van Boven, A., Clement, W., Bron, S.,Venema, G. Arch.Microbiol 1984 ;139(4):311-318

1984

Direct plasmid transfer from replica-plated E. coli colonies to competent B. subtilis cells. Identification of an E. coli clone carrying the hisH and tyrA genes of B. subtilis van Randen, J., Venema, G. Mol Gen.Genet 1984 ;195(1):57-61

1984

Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and Escherichia coli Kok, J., van der Vossen, J. M. B. M.,Venema, G. Appl Environ.Microbiol 1984 ;48(4):726-731
pdf for mg0063

1984

Transformation in Bacillus subtilis: purification and partial characterization of a membrane-bound DNA-binding protein Smith, H., Wiersma, K., Bron, S.,Venema, G. J Bacteriol 1983 ;156(1):101-108

1983

Transformation in Bacillus subtilis: properties of DNA-binding-deficient mutants Smith, H., de Vos, W.,Bron, S. J Bacteriol 1983 ;153(1):12-20

1983

Resistance of bacteriophage H1 to restriction and modification by Bacillus subtilis R Bron, S., Luxen, E.,Venema, G. J Virol. 1983 ;46(3):703-708

1983

Introduction of a Streptococcus cremoris plasmid in Bacillus subtilis Vosman, B., Venema, G. J Bacteriol 1983 ;156(2):920-921

1983

Inhibition of DNA replication by transformation in a Haemophilus influenzae mutant carrying an altered Rec-1 protein Kooistra, J., van Boxel, T.,Venema, G. J Bacteriol 1983 ;154(2):686-692

1983

Cloning and expression of the Escherichia coli recA gene in Bacillus subtilis de Vos, W. M., de Vries, S. C.,Venema, G. Gene 1983 ;25(2):301-308

1983

Characterization of a conditionally transformation-deficient mutant of Haemophilus influenzae that carries a mutation in the rec-1 gene region Kooistra, J., van Boxel, T.,Venema, G. J Bacteriol 1983 ;153(2):852-860

1983

Unstable association in vitro between donor and recipient DNA in Bacillus subtilis van Randen, J., Wiersma, K.,Venema, G. J Bacteriol 1982 ;152(1):275-283

1982

Transformation-deficient mutants of Bacillus subtilis impaired in competence-specific nuclease activities Mulder, J. A.Venema, G. J Bacteriol 1982 ;152(1):166-174

1982

Transformation of Bacillus subtilis competent cells: identification of a protein involved in recombination de Vos, W. M., Venema, G. Mol Gen.Genet 1982 ;187(3):439-445

1982

The effect of chlorpromazine on transformation in Bacillus subtilis Mooibroek, H.Venema, G. Mol Gen.Genet 1982 ;185(1):165-168

1982

Role of proton motive force in genetic transformation of Bacillus subtilis van Nieuwenhoven, M. H., Hellingwerf, K. J., Venema, G.,Konings, W. N. J Bacteriol 1982 ;151(2):771-776

1982

Restriction and modification in Bacillus subtilis: effects on transfection under marker rescue conditions Bron, S., Luxen, E.,Venema, G. J Virol. 1982 ;42(2):357-364
pdf for mg0050

1982

Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis. II. Unstable association of heterologous DNA with the recipient chromosome te Riele, H. P., Venema, G. Genetics 1982 ;102(3):329-340

1982

Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis. I. Processing of B. pumilus and B. licheniformis DNA in B. subtilis te Riele, H. P., Venema, G. Genetics 1982 ;101(2):179-188

1982

Isolation and partial characterization of Bacillus subtilis mutants impaired in DNA entry Mulder, J. A.Venema, G. J Bacteriol 1982 ;150(1):260-268

1982

Initiation of recombination during transformation of Bacillus subtilis requires no extensive homologous sequences van Randen, J., Wiersma, K.,Venema, G. Mol Gen.Genet 1982 ;188(3):499-507

1982

Effect of 4,5',8-trimethylpsoralen interstrand cross-links present in recipient Bacillus subtilis on the integration of transforming DNA Mooibroek, H., van Randen, J.,Venema, G. J Bacteriol 1982 ;152(2):669-675

1982

Plasmid transformation in Bacillus subtilis: fate of plasmid DNA de Vos, W. M., Venema, G., Canosi, U.,Trautner, T. A. Mol Gen.Genet 1981 ;181(4):424-433

1981

Inactivation of transforming Bacillus subtilis deoxyribonucleic acid by monoadducts of 4,5',8-trimethylpsoralen te Riele, H. P., van Sluis, P.,Venema, G. J Bacteriol 1981 ;145(2):832-839

1981

Fate of plasmid DNA in transformation of Bacillus subtilis protoplasts de Vos, W. M., Venema, G. Mol Gen.Genet 1981 ;182(1):39-43

1981

Effect of ethylenediaminetetraacetic acid on deoxyribonucleic acid entry and recombination in transformation of a wild-type strain and a rec-1 mutant of Haemophilus influenzae Noteborn, M., Venema, G.,Kooistra, J. J Bacteriol 1981 ;145(3):1189-1195

1981

Assimilation of single-stranded donor deoxyribonucleic acid fragments by nucleoids of competent cultures of Bacillus subtilis van Randen, J., Venema, G. J Bacteriol 1981 ;145(3):1177-1188

1981

The effect of trimethylpsoralen--crosslinks on entry of donor DNA in transformation and transfection of Bacillus subtilis Venema, G., Canosi, U. Mol Gen.Genet 1980 ;179(1):1-11

1980

Restriction and modification in B. subtilis: the role of homology between donor and recipient DNA in transformation and transfection Bron, S., Luxen, E.,Trautner, T. A. Mol Gen.Genet 1980 ;179(1):111-117

1980

Restriction and modification in B. subtilis: effects on transformation and transfection with native and single-stranded DNA Bron, S., Luxen, E., Venema, G.,Trautner, T. A. Mol Gen.Genet 1980 ;179(1):103-110

1980

Purification and properties of the Bsu endonuclease Bron, S., Horz, W. Methods Enzymol. 1980 ;65(1):112-132

1980

Properties of Haemophilus influenzae mutants that are slightly recombination deficient and carry a mutation in the rec-1 gene region Kooistra, J., Venema, G. J Bacteriol 1980 ;142(3):829-835

1980

DNA binding and deoxyribonuclease activity in Bacillus subtilis during temperature-induced competence development Espinosa, M., Joenje, H.,Venema, G. J Gen.Microbiol 1980 ;121(1):79-84

1980

Deoxyribonucleic acid-binding properties and membrane protein composition of a competence-deficient mutant of Haemophilus influenzae Kooistra, J., van Boxel, T.,Venema, G. J Bacteriol 1980 ;144(1):22-27

1980

Bacterial transformation Venema, G. Adv.Microb Physiol. 1979 ;19(0):245-331

1979

Transformation in Bacillus subtilis: characterization of an intermediate in recombination observed during transformation Buitenwerf, J., Venema, G. Mol Gen.Genet 1978 ;160(1):67-75

1978

An unstable donor-recipient DNA complex in transformation of Bacillus subtilis Popowski, J.Venema, G. Mol Gen.Genet 1978 ;166(2):119-126

1978

Transformation in bacillus subtilis: fate of transforming DNA in transformation deficient mutants Buitenwerf, J., Venema, G. Mol Gen.Genet 1977 ;151(2):203-213

1977

Transformation in Bacillus subtilis: biological and physical evidence for a novel DNA-intermediate in synchronously transforming cells Buitenwerf, J., Venema, G. Mol Gen.Genet 1977 ;156(2):145-155

1977

Characteristics of a complex formed by a nonintegrated fraction of transforming DNA and Bacillus subtilis recipient cell constituents Pieniazek, D., Piechowska, M.,Venema, G. Mol Gen.Genet 1977 ;156(3):251-261

1977

Effect of adenosine 5'-triphosphate-dependent deoxyribonuclease deficiency on properties and transformation of Haemophilus influenzae strains Kooistra, J., Venema, G. J Bacteriol 1976 ;128(2):549-556

1976

Restriction and modification in B. subtilis. Purification and general properties of a restriction endonuclease from strain R Bron, S., Murray, K.,Trautner, T. A. Mol Gen.Genet 1975 ;143(1):13-23

1975

Restriction and modification in B. subtilis. Nucleotide sequence recognised by restriction endonuclease R. Bsu R from strain R Bron, S., Murray, K. Mol Gen.Genet 1975 ;143(1):25-33

1975

Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from competent and noncompetent Bacillus subtilis Joenje, H., Konings, W. N.,Venema, G. J Bacteriol 1975 ;121(3):771-776

1975

Different nuclease activities in competent and noncompetent Bacillus subtilis Joenje, H.Venema, G. J Bacteriol 1975 ;122(1):25-33

1975

Transfection of Bacillus subtilis with bacteriophage H1 DNA: fate of transfecting DNA and transfection enhancement in B. subtilis uur+ and uur- strains Arwert, F., Venema, G. Mol Gen.Genet 1974 ;128(1):55-72

1974

Restriction and modification in B. subtilis. Biological aspects Trautner, T. A., Pawlek, B., Bron, S.,Anagnostopoulos, C. Mol Gen.Genet 1974 ;131(3):181-191

1974

Protease-sensitive transfection of Bacillus subtilis with bacteriophage GA-1 DNA: a probable case of heterologous transfection Arwert, F., Venema, G. J Virol. 1974 ;13(3):584-589

1974

Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from Bacillus subtilis 168 Joenje, H., Konings, W. N.,Venema, G. J Bacteriol 1974 ;119(3):784-794

1974

Fate of donor deoxyribonucleic acid in a highly transformation-deficient strain of Haemophilus influenzae Kooistra, J., Venema, G. J Bacteriol 1974 ;119(3):705-717

1974

Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: ultrastructure of competent and noncompetent cells and cellular changes during development of competence Vermeulen, C. A., Venema, G. J Bacteriol 1974 ;118(2):334-341

1974

Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid absorption in Bacillus subtilis: localization of uptake and of transport of transforming deoxyribonucleic acid in competent cells Vermeulen, C. A., Venema, G. J Bacteriol 1974 ;118(2):342-350

1974

Transformation in Bacillus subtilis. Fate of newly introduced transforming DNA Arwert, F., Venema, G. Mol Gen.Genet 1973 ;123(2):185-198

1973

Poor transformability with novr and eryr donor DNA of some mitomycin-C-sensitive strains of Haemophilus influenzae Kooistra, J., Venema, G. Mutat.Res 1973 ;20(3):313-326

1973

Isolation and partial characterization of a temperature-sensitive mutant of Bacillus subtilis impaired in the development of competence for genetic transformation Joenje, H., Admiraal, W.,Venema, G. J Gen.Microbiol 1973 ;78(1):67-77

1973

Ultraviolet inactivation and excision-repair in Bacillus subtilis. IV. Integration and repair of ultraviolet-inactivated transforming DNA Bron, S., Venema, G. Mutat.Res 1972 ;15(4):395-409

1972

Ultraviolet inactivation and excision-repair in Bacillus subtilis. II. Differential inactivation and differential repair of transforming markers Bron, S., Venema, G. Mutat.Res 1972 ;15(1):11-22

1972

Ultraviolet inactivation and excision-repair in Bacillus subtilis. I. Construction and characterization of a transformable eightfold auxotrophic strain and two ultraviolet-sensitive derivatives Bron, S., Venema, G. Mutat.Res 1972 ;15(1):1-10

1972

Ultraviolet inactivation and excision-repair in Bacillus subtilis. 3. Sensitized photoinactivation of transforming DNA, and the effect of thymine dimers on differential marker inactivation and differential marker repair Bron, S., Venema, G. Mutat.Res 1972 ;15(4):377-393

1972

The effect of competence regime on competence, DNA absorption and integration of DNA in cultures of Bacillus subtilis Vermeulen, C. A., Venema, G. J Gen.Microbiol 1972 ;71(3):415-424

1972

Stimulation of the development of competence by culture fluids in Bacillus subtilis transformation Joenje, H., Gruber, M.,Venema, G. Biochim.Biophys.Acta 1972 ;262(2):189-199

1972

In vitro excision-repair of ultraviolet-irradiated transforming DNA from Bacillus subtilis Heijneker, H. L., Pannekoek, H., Oosterbaan, R. A., Pouwels, P. H., Bron, S., Arwert, F.,Venema, G. Proc Natl Acad Sci U S A 1971 ;68(12):2967-2971

1971

Autoradiographic estimation of competence and the relationship between competence and transformability in cultures of Bacillus subtilis Vermeulen, C. A., Venema, G. J Gen.Microbiol 1971 ;69(2):239-252

1971

Fate of donor DNA in some poorly transformable strains of Haemophilus influenzae Kooistra, J., Venema, G. Mutat.Res 1970 ;9(3):245-253

1970

Penetration of thymine-starved bacterial DNA during transformation of B. subtilis 168 T- Sicard, N.Venema, G. Biochem Biophys.Res Commun. 1969 ;36(4):647-650

1969

Evidence for the involvement of membranous bodies in the processes leading to genetic transformation in Bacillus subtilis Wolstenholme, D. R., Vermeulen, C. A.,Venema, G. J Bacteriol 1966 ;92(4):1111-1121

1966

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