Cesin, a short natural variant of nisin, displays potent antimicrobial activity against major pathogens despite
lacking two C-terminal macrocycles.
Guo L; Wambui J; Wang C; Muchaamba F; Fernandez-Cantos MV; Broos J; Tasara T;
Kuipers OP; Stephan R
Microbiol Spectr 2023 ;11(5):e0531922-0 pubmedlink 37754751 2023 |
AT(2) receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung remodelling.
Villela DC; Namsolleck P; Reichetzeder C; Moll GN
Peptides 2023 ;170(0):171106-0 pubmedlink 37742799 2023 |
Evolving views on the first two ligands of the angiotensin II type 2 receptor. From putative antagonists to
potential agonists?
Wagenaar GTM; Moll GN
Eur J Pharmacol 2023 ;961(0):176189-0 pubmedlink 37951489 2023 |
Systematic analysis of drug combinations against Gram-positive bacteria.
Cacace E; Kim V; Varik V; Knopp M; Tietgen M; Brauer-Nikonow A; Inecik K; Mateus A; Milanese A; Mårli MT; Mitosch
K; Selkrig J; Brochado AR; Kuipers OP; Kjos M; Zeller G; Savitski MM; Göttig S; Huber W; Typas A
Nat Microbiol 2023 ;8(11):2196-2212 pubmedlink 37770760 2023 |
Engineering lanthipeptides by introducing a large variety of RiPP modifications to obtain new-to-nature bioactive
peptides.
Fu Y; Xu Y; Ruijne F; Kuipers OP
FEMS Microbiol Rev 2023 ;47(3):0-0 pubmedlink 37096385 2023 |
Elucidating the Mechanism of Action of the Gram-Negative-Pathogen-Selective Cyclic Antimicrobial Lipopeptide
Brevicidine.
Zhao X; Zhong X; Yang S; Deng K; Liu L; Song X; Zou Y; Li L; Zhou X; Jia R; Lin J; Tang H; Ye
G; Yang J; Zhao S; Lang Y; Wan H; Yin Z; Kuipers OP
Antimicrob Agents Chemother 2023 ;67(5):e0001023-0 pubmedlink 36912655 2023 |
p140Cap inhibits b-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune
response.
Salemme V; Vedelago M; Sarcinella A; Moietta F; Piccolantonio A; Moiso E; Centonze G; Manco M; Guala A; Lamolinara
A; Angelini C; Morellato A; Natalini D; Calogero R; Incarnato D; Oliviero S; Conti L; Iezzi M; Tosoni D;
Bertalot G; Freddi S; Tucci FA; De Sanctis F; Frusteri C; Ugel S; Bronte V; Cavallo F; Provero P; Gai M; Taverna D;
Turco E; Pece S; Defilippi P
Nat Commun 2023 ;14(1):2350-0 pubmedlink 37169737 2023 |
Leader and Terminal Residue Requirements for Circularin A Biosynthesis Probed by Systematic Mutational Analyses.
Liu F; van Heel AJ; Kuipers OP
ACS Synth Biol 2023 ;12(3):852-862 pubmedlink 36857413 2023 |
5-Ethynyluridine: A Bio-orthogonal Uridine Variant for mRNA-Based Therapies and Vaccines.
Maassen S; Coenen B; Dulk S; van der Werff M; Warner H; Spada F; Frischmuth T; Incarnato D; van den
Bogaart G
Chembiochem 2023 ;24(5):e202200658-0 pubmedlink 36594506 2023 |
Probing the dynamic RNA structurome and its functions.
Spitale RC; Incarnato D
Nat Rev Genet 2023 ;24(3):178-196 pubmedlink 36348050 2023 |
Pesticides, trace elements and pharmaceuticals in tea samples available in Belgian retail shops and the risk
associated upon acute and chronic exposure.
Szternfeld P; Montalvo D; Broos J; Cheyns K; Joly L; Vanhee C
Food Addit Contam Part B Surveill 2023 ;16(1):58-68 pubmedlink 36537161 2023 |
Galanin 2 Receptor: A Novel Target for a Subset of Pancreatic Ductal Adenocarcinoma.
Namsolleck P; Kofler B; Moll GN
Int J Mol Sci 2023 ;24(12):0-0 pubmedlink 37373336 2023 |
Investigating the NRAS 5' UTR as a target for small molecules.
Balaratnam S; Torrey ZR; Calabrese DR; Banco MT; Yazdani K; Liang X; Fullenkamp CR; Seshadri S; Holewinski RJ;
Andresson T; Ferré-D\'Amaré AR; Incarnato D; Schneekloth JS Jr
Cell Chem Biol 2023 ;30(6):643-657.e8 pubmedlink 37257453 2023 |
Lipidated variants of the antimicrobial peptide nisin produced via incorporation of methionine analogs for click
chemistry show improved bioactivity.
Guo L; Wang C; Broos J; Kuipers OP
J Biol Chem 2023 ;299(7):104845-0 pubmedlink 37209826 2023 |
Emulating nonribosomal peptides with ribosomal biosynthetic strategies.
Mordhorst S; Ruijne F; Vagstad AL; Kuipers OP; Piel J
RSC Chem Biol 2023 ;4(1):7-36 pubmedlink 36685251 2023 |
DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells.
Lauria A; Meng G; Proserpio V; Rapelli S; Maldotti M; Polignano IL; Anselmi F; Incarnato D; Krepelova A;
Donna D; Levra Levron C; Donati G; Molineris I; Neri F; Oliviero S
Nat Commun 2023 ;14(1):367-0 pubmedlink 36690616 2023 |
Investigating the Specificity of the Dehydration and Cyclization Reactions in Engineered Lanthipeptides by
Synechococcal SyncM.
Arias-Orozco P; Yi Y; Ruijne F; Cebrián R; Kuipers OP
ACS Synth Biol 2023 ;12(1):164-177 pubmedlink 36520855 2023 |
LP2, a stable lanthipeptide derived from cAng-(1-7), exerts myeloprotective action in mice.
Namsolleck P; Rodgers KE; Franklin R; Moll GN
Eur J Haematol 2023 ;0(0):0-0 aheadofprint pubmedlink 36656652 2023 |
Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
Monnot GC; Wegrecki M; Cheng TY; Chen YL; Sallee BN; Chakravarthy R; Karantza IM; Tin SY; Khaleel AE; Monga I;
Uwakwe LN; Tillman A; Cheng B; Youssef S; Ng SW; Shahine A; Garcia-Vilas JA; Uhlemann AC; Bordone LA; Han A; Rohde
CH; Ogg G; Moody DB; Rossjohn J; de Jong A
Nat Immunol 2023 ;24(1):110-122 pubmedlink 36550321 2023 |
LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived
xenografts of colorectal carcinoma in mice.
Namsolleck P; de Vries L; Moll GN
Peptides 2023 ;160(0):170920-0 pubmedlink 36493954 2023 |
Uncovering the diversity and distribution of biosynthetic gene clusters of prochlorosins and other putative RiPPs
in marine Synechococcus strains.
Arias-Orozco P; Zhou L; Yi Y; Cebrián R; Kuipers OP
Microbiol Spectr 2023 ;0(0):e0361123-0 aheadofprint pubmedlink 38088546 2023 |
Synthesis and antimicrobial activity of aminoalkyl resveratrol derivatives inspired by cationic peptides.
Cebrián R; Lucas R; Fernández-Cantos MV; Slot K; Peñalver P; Martínez-García M; Párraga-Leo A; de Paz
MV; García F; Kuipers OP; Morales JC
J Enzyme Inhib Med Chem 2023 ;38(1):267-281 pubmedlink 36600674 2023 |
Seeing the Invisibles: Detection of Peptide Enantiomers, Diastereomers, and Isobaric Ring Formation in
Lanthipeptides Using Nanopores.
Abraham Versloot RC; Arias-Orozco P; Tadema MJ; Rudolfus Lucas FL; Zhao X; Marrink SJ;
Kuipers OP; Maglia G
J Am Chem Soc 2023 ;0(0):0-0 aheadofprint pubmedlink 37579582 2023 |
m(6)A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis.
Ciesla M; Ngoc PCT; Muthukumar S; Todisco G; Madej M; Fritz H; Dimitriou M; Incarnato D; Hellström-Lindberg
E; Bellodi C
Mol Cell 2023 ;83(7):1165-1179.e11 pubmedlink 36944332 2023 |
Cell-to-cell non-conjugative plasmid transfer between Bacillus subtilis and lactic acid bacteria.
Morawska LP; Kuipers OP
Microb Biotechnol 2023 ;16(4):784-798 pubmedlink 36547214 2023 |
Bioinformatic mining for RiPP biosynthetic gene clusters in Bacteroidales reveals possible new subfamily
architectures and novel natural products.
Fernandez-Cantos MV; Garcia-Morena D; Yi Y; Liang L; Gómez-Vázquez E; Kuipers OP
Front Microbiol 2023 ;14(0):1219272-0 pubmedlink 37469430 2023 |
Advances in the preclinical characterization of the antimicrobial peptide AS-48.
Cebrián R; Martínez-García M; Fernández M; García F; Martínez-Bueno M; Valdivia E; Kuipers OP;
Montalbán-López M; Maqueda M
Front Microbiol 2023 ;14(0):1110360-0 pubmedlink 36819031 2023 |
Food safety and biological control; genomic insights and antimicrobial potential of Bacillus velezensis FB2
against agricultural fungal pathogens.
Hammad M; Ali H; Hassan N; Tawab A; Salman M; Jawad I; de Jong A; Moreno CM; Kuipers OP; Feroz
Y; Rashid MH
PLoS One 2023 ;18(11):e0291975-0 pubmedlink 37963161 2023 |
Stress-induced activation of the proline biosynthetic pathway in Bacillus subtilis: a population-wide and
single-cell study of the osmotically controlled proHJ promoter.
Morawska LP; Detert Oude Weme RGJ; Frenzel E; Dirkzwager M; Hoffmann T; Bremer E;
Kuipers OP
Microb Biotechnol 2022 ;0(0):0-0 aheadofprint pubmedlink 35593133 2022 |
Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing
Mechanism.
Viel JH; Kuipers OP
ACS Synth Biol 2022 ;11(5):1949-1957 pubmedlink 35504017 2022 |
Computational Approaches for RNA Structure Ensemble Deconvolution from Structure Probing Data.
Aviran S; Incarnato D
J Mol Biol 2022 ;0(0):167635-0 aheadofprint pubmedlink 35595163 2022 |
Membrane composition and organization of Bacillus subtilis 168 and its genome-reduced derivative miniBacillus
PG10.
van Tilburg AY; Warmer P; van Heel AJ; Sauer U; Kuipers OP
Microb Biotechnol 2022 ;15(5):1633-1651 pubmedlink 34856064 2022 |
SHAPE-guided RNA structure homology search and motif discovery.
Morandi E; van Hemert MJ; Incarnato D
Nat Commun 2022 ;13(1):1722-0 pubmedlink 35361788 2022 |
G-Quadruplex DNA as a Target in Pathogenic Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its
Mode of Action.
Cebrián R; Belmonte-Reche E; Pirota V; de Jong A; Morales JC; Freccero M; Doria F; Kuipers OP
J Med Chem 2022 ;65(6):4752-4766 pubmedlink 34928608 2022 |
The acetyltransferase p300 is recruited in trans to multiple enhancer sites by lncSmad7.
Maldotti M; Lauria A; Anselmi F; Molineris I; Tamburrini A; Meng G; Polignano IL; Scrivano MG; Campestre F; Simon
LM; Rapelli S; Morandi E; Incarnato D; Oliviero S
Nucleic Acids Res 2022 ;50(5):2587-2602 pubmedlink 35137201 2022 |
Diversity of bet-hedging strategies in microbial communities-Recent cases and insights.
Morawska LP; Hernandez-Valdes JA; Kuipers OP
WIREs Mech Dis 2022 ;14(2):e1544-0 pubmedlink 35266649 2022 |
STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts.
Avalle L; Raggi L; Monteleone E; Savino A; Viavattene D; Statello L; Camperi A; Stabile SA; Salemme V; De Marzo N;
Marino F; Guglielmi C; Lobascio A; Zanini C; Forni M; Incarnato D; Defilippi P; Oliviero S; Poli V
Oncogene 2022 ;41(10):1456-1467 pubmedlink 35042959 2022 |
Trade-offs predicted by metabolic network structure give rise to evolutionary specialization and phenotypic
diversification.
Ekkers DM; Tusso S; Moreno-Gamez S; Rillo MC; Kuipers OP; van Doorn GS
Mol Biol Evol 2022 ;39(6):0-0 pubmedlink 35679426 2022 |
Probing the Conformational States of Thimet Oligopeptidase in Solution.
Marcondes MFM; Santos GS; Bronze F; Machado MFM; Perez KR; Hesselink R; de Vries MP; Broos J;
Oliveira V
Int J Mol Sci 2022 ;23(13):0-0 pubmedlink 35806299 2022 |
Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens.
Cebrián R; Li Q; Peñalver P; Belmonte-Reche E; Andrés-Bilbao M; Lucas R; de Paz MV; Kuipers OP;
Morales JC
J Nat Prod 2022 ;85(6):1459-1473 pubmedlink 35621995 2022 |
Analysis of Cross-Functionality within LanBTC Synthetase Complexes from Different Bacterial Sources with Respect
to Production of Fully Modified Lanthipeptides.
Chen J; Kuipers OP
Appl Environ Microbiol 2022 ;88(2):e0161821-0 pubmedlink 34788067 2022 |
Riboswitch RS(thiT) as a Molecular Tool in Lactococcus lactis.
Hernández-Ortega EP; van der Meulen S; Kuijpers LJ; Kok J
Appl Environ Microbiol 2022 ;88(4):e0176421-0 pubmedlink 34936833 2022 |
Biocontrol properties from phyllospheric bacteria isolated from Solanum lycopersicum and Lactuca sativa and genome
mining of antimicrobial gene clusters.
Muñoz CY; Zhou L; Yi Y; Kuipers OP
BMC Genomics 2022 ;23(1):152-0 pubmedlink 35189837 2022 |
Stapling of Peptides Potentiates the Antibiotic Treatment of Acinetobacter baumannii In Vivo.
Schouten GK; Paulussen FM; Kuipers OP; Bitter W; Grossmann TN; van Ulsen P
Antibiotics (Basel) 2022 ;11(2):0-0 pubmedlink 35203875 2022 |
Hmga2 protein loss alters nuclear envelope and 3D chromatin structure.
Divisato G; Chiariello AM; Esposito A; Zoppoli P; Zambelli F; Elia MA; Pesole G; Incarnato D; Passaro F;
Piscitelli S; Oliviero S; Nicodemi M; Parisi S; Russo T
BMC Biol 2022 ;20(1):171-0 pubmedlink 35918713 2022 |
Intranasal Delivery of a Methyllanthionine-Stabilized Galanin Receptor-2-Selective Agonist Reduces Acute Food
Intake.
Kuipers A; Balaskó M; Pétervári E; Koller A; Brunner SM; Moll GN; Kofler B
Neurotherapeutics 2021 ;18(4):2737-2752 pubmedlink 34859381 2021 |
Heterologous Expression of Mersacidin in Escherichia coli Elucidates the Mode of Leader Processing.
Viel JH; Jaarsma AH; Kuipers OP
ACS Synth Biol 2021 ;10(3):600-608 pubmedlink 33689311 2021 |
Antimicrobial activity screening of rhizosphere soil bacteria from tomato and genome-based analysis of their
antimicrobial biosynthetic potential.
Zhou L; Song C; Li Z; Kuipers OP
BMC Genomics 2021 ;22(1):29-0 pubmedlink 33413100 2021 |
Outer-membrane-acting peptides and lipid II-targeting antibiotics cooperatively kill Gram-negative pathogens.
Li Q; Cebrián R; Montalbán-López M; Ren H; Wu W; Kuipers OP
Commun Biol 2021 ;4(1):31-0 pubmedlink 33398076 2021 |
Draft Genome Sequences of a Bacillus subtilis Strain, a Bacillus velezensis Strain, a Paenibacillus Strain, and an
Acinetobacter baumannii Strain, All Isolated from the Phyllosphere of Lactuca sativa or Solanum lycopersicum.
Muñoz CY; de Jong A; Kuipers OP
Microbiol Resour Announc 2021 ;10(4):0-0 pubmedlink 33509984 2021 |
Combinatorial biosynthesis for the generation of new-to-nature peptide antimicrobials.
Ruijne F; Kuipers OP
Biochem Soc Trans 2021 ;49(1):203-215 pubmedlink 33439248 2021 |
Antiviral activities and applications of ribosomally synthesized and post-translationally modified peptides
(RiPPs).
Fu Y; Jaarsma AH; Kuipers OP
Cell Mol Life Sci 2021 ;0(0):1-20 aheadofprint pubmedlink 33532865 2021 |
Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs)
via Cu(II) -Catalyzed β-Borylation of Dehydroamino Acids.
de Vries RH; Viel JH; Kuipers OP; Roelfes G
Angew Chem Int Ed Engl 2021 ;60(8):3946-3950 pubmedlink 33185967 2021 |
LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study.
Namsolleck P; Richardson A; Moll GN; Mescheder A
Peptides 2021 ;136(0):170468-0 pubmedlink 33253776 2021 |
Novel modifications of nonribosomal peptides from Brevibacillus laterosporus MG64 and investigation of their mode
of action.
Li Z; de Vries RH; Chakraborty P; Song C; Zhao X; Scheffers DJ; Roelfes
G; Kuipers OP
Appl Environ Microbiol 2020 ;11(9):e00133-0 pubmedlink 32978140 2020 |
Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration
events.
Kurushima J; Campo N; van Raaphorst R; Cerckel G; Polard P; Veening JW
Elife 2020 ;9(1):297-0 pubmedlink 32965219 2020 |
New developments in RiPP discovery, enzymology and engineering.
Montalbán-López M; Scott TA; Ramesh S; Rahman IR; van Heel AJ; Viel JH; Bandarian V; Dittmann
E; Genilloud O; Goto Y; Grande Burgos MJ; Hill C; Kim S; Koehnke J; Latham JA; Link AJ; MartÃnez B; Nair
SK; Nicolet Y; Rebuffat S; Sahl HG; Sareen D; Schmidt EW; Schmitt L; Severinov K; Süssmuth RD; Truman AW; Wang
H; Weng JK; van Wezel GP; Zhang Q; Zhong J; Piel J; Mitchell DA; Kuipers OP; van der Donk WA
Nat Prod Rep 2020 ;61(0):72-0 pubmedlink 32935693 2020 |
Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study.
Ielpo B; Podda M; Pellino G; Pata F; Caruso R; Gravante G; Di Saverio S
Br J Surg 2020 ;0(0):0-0 aheadofprint pubmedlink 33030744 2020 |
Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors.
Moll GN; Kuipers A; Rink R; Bosma T; de Vries L; Namsolleck P
Biochem Soc Trans 2020 ;48(5):2195-2203 pubmedlink 33125486 2020 |
Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq.
Liu X; Kimmey JM; Matarazzo L; de Bakker V; Van Maele L; Sirard JC; Nizet V; Veening JW
Cell Host Microbe 2020 ;0(0):0-0 aheadofprint pubmedlink 33120116 2020 |
Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae.
Sorg RA; Gallay C; Van Maele L; Sirard JC; Veening JW
Proc Natl Acad Sci U S A 2020 ;27(4):544-0 pubmedlink 33087560 2020 |
Microbial competition reduces metabolic interaction distances to the low µm-range.
van Tatenhove-Pel RJ; Rijavec T; Lapanje A; van Swam I; Zwering E; Hernandez-Valdes JA; Kuipers OP;
Picioreanu C; Teusink B; Bachmann H
ISME J 2020 ;6(1):30-0 pubmedlink 33077887 2020 |
Prevalence of phase variable epigenetic invertons among host-associated bacteria.
Huang X; Wang J; Li J; Liu Y; Liu X; Li Z; Kurniyati K; Deng Y; Wang G; Ralph JD; De Ste Croix M;
Escobar-Gonzalez S; Roberts RJ; Veening JW; Lan X; Oggioni MR; Li C; Zhang JR
Nucleic Acids Res 2020 ;48(20):11468-11485 pubmedlink 33119758 2020 |
Symposium on Lactic Acid Bacteria-reading while waiting for a meeting.
Teusink B; Kuipers OP; Moineau S
FEMS Microbiol Rev 2020 ;27(10):1262-0 pubmedlink 33197931 2020 |
Subcellular Localization and Assembly Process of the Nisin Biosynthesis Machinery in Lactococcus lactis.
Chen J; van Heel AJ; Kuipers OP
mBio 2020 ;11(6):0-0 pubmedlink 33173006 2020 |
An Engineered Double Lipid II Binding Motifs-Containing Lantibiotic Displays Potent and Selective Antimicrobial
Activity against Enterococcus faecium.
Zhao X; Yin Z; Breukink E; Moll GN; Kuipers OP
Antimicrob Agents Chemother 2020 ;64(6):0-0 pubmedlink 32179527 2020 |
Modulation of circRNA Metabolism by m(6)A Modification.
Di Timoteo G; Dattilo D; Centrón-Broco A; Colantoni A; Guarnacci M; Rossi F; Incarnato D; Oliviero S;
Fatica A; Morlando M; Bozzoni I
Cell Rep 2020 ;31(6):107641-0 pubmedlink 32402287 2020 |
The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in
human PSCs.
Zorzan I; Pellegrini M; Arboit M; Incarnato D; Maldotti M; Forcato M; Tagliazucchi GM; Carbognin E;
Montagner M; Oliviero S; Martello G
Nat Commun 2020 ;11(1):2364-0 pubmedlink 32398665 2020 |
A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium.
Hernandez-Valdes JA; van Gestel J; Kuipers OP
Nat Commun 2020 ;11(1):1203-0 pubmedlink 32139702 2020 |
Complete Genome Sequences of 28 Lactococcal Bacteriophages Isolated from Failed Dairy Fermentation Processes.
Marcelli B; de Jong A; Janzen T; Serrano M; Kok J; Kuipers OP
Microbiol Resour Announc 2020 ;9(12):0-0 pubmedlink 32193244 2020 |
In vivo dual RNA-seq reveals that neutrophil recruitment underlies differential tissue tropism of Streptococcus
pneumoniae.
Minhas V; Aprianto R; McAllister LJ; Wang H; David SC; McLean KT; Comerford I; McColl SR; Paton JC;
Veening JW; Trappetti C
Commun Biol 2020 ;3(1):293-0 pubmedlink 32504007 2020 |
Endoribonuclease YbeY Is Essential for RNA Processing and Virulence in Pseudomonas aeruginosa.
Xia Y; Weng Y; Xu C; Wang D; Pan X; Tian Z; Xia B; Li H; Chen R; Liu C; Jin Y; Bai F; Cheng Z;
Kuipers OP; Wu W
mBio 2020 ;11(3):3-0 pubmedlink 32605982 2020 |
Characterization of two relacidines belonging to a novel class of circular lipopeptides that act against
Gram-negative bacterial pathogens.
Li Z; Chakraborty P; de Vries RH; Song C; Zhao X; Roelfes G; Scheffers
DJ; Kuipers OP
Environ Microbiol 2020 ;11(0):e00133-0 pubmedlink 32608161 2020 |
High-Throughput Screening for Substrate Specificity-Adapted Mutants of the Nisin Dehydratase NisB.
Zhao X; Cebrián R; Fu Y; Rink R; Bosma T; Moll GN; Kuipers OP
ACS Synth Biol 2020 ;9(6):1468-1478 pubmedlink 32374981 2020 |
MiniBacillus PG10 as a convenient and effective production host for lantibiotics.
van Tilburg AY; van Heel AJ; Stülke J; de Kok NAW; Rueff AS; Kuipers
OP
ACS Synth Biol 2020 ;0(0):0-0 aheadofprint pubmedlink 32551553 2020 |
Another breaker of the wall: The biological function of the Usp45 protein of Lactococcus lactis.
Hernandez-Valdes JA; Huang C; Kok J; Kuipers OP
Appl Environ Microbiol 2020 ;0(0):0-0 aheadofprint pubmedlink 32532874 2020 |
Analyses of competent and non-competent subpopulations of Bacillus subtilis reveal yhfW, yhxC and ncRNAs as novel
players in competence.
Boonstra M; Schaffer M; Sousa J; Morawska L; Holsappel S; Hildebrandt P; Sappa PK; Rath H;
de Jong A; Lalk M; Mäder U; Völker U; Kuipers OP
Environ Microbiol 2020 ;22(6):2312-2328 pubmedlink 32249531 2020 |
A de novo reciprocal chromosomal translocation t(3;6)(p14;q26) in the black Lucano pig.
Genualdo V; Rossetti C; Pauciullo A; Musilova P; Incarnato D; Perucatti A
Reprod Domest Anim 2020 ;55(6):677-682 pubmedlink 32125727 2020 |
Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis.
Zhang B; Liu X; Lambert E; Mas G; Hiller S; Veening JW; Perez C
Nat Struct Mol Biol 2020 ;27(6):561-569 pubmedlink 32367070 2020 |
Synthesis and Characterization of Heterodimers and Fluorescent Nisin Species by Incorporation of Methionine
Analogs and Subsequent Click Chemistry.
Deng J; Viel JH; Chen J; Kuipers OP
ACS Synth Biol 2020 ;21(1):157-0 pubmedlink 32786360 2020 |
Mimicry of a Non-ribosomally Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and Post-translational
Modification.
Zhao X; Li Z; Kuipers OP
Cell Chem Biol 2020 ;0(0):0-0 aheadofprint pubmedlink 32707039 2020 |
Editing of the proteolytic system of Lactococcus lactis increases its bioactive potential.
Huang C; Kok J
Appl Environ Microbiol 2020 ;86(16):0-0 pubmedlink 32680863 2020 |
Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery.
Br J Surg 2020 ;107(2):e161-e169 pubmedlink 31595986 2020 |
Characterization of plant growth-promoting rhizobacteria from perennial ryegrass and genome mining of novel
antimicrobial gene clusters.
Li Z; Song C; Yi Y; Kuipers OP
BMC Genomics 2020 ;21(1):157-0 pubmedlink 32050906 2020 |
Microdroplet screening and selection for improved microbial production of extracellular compounds.
van Tatenhove-Pel RJ; Hernandez-Valdes JA; Teusink B; Kuipers OP; Fischlechner M; Bachmann H
Curr Opin Biotechnol 2020 ;61(0):72-81 pubmedlink 31770655 2020 |
YbeY controls the type III and type VI secretion systems and biofilm formation through RetS in Pseudomonas
aeruginosa.
Xia Y; Xu C; Wang D; Weng Y; Jin Y; Bai F; Cheng Z; Kuipers OP; Wu W
Appl Environ Microbiol 2020 ;0(0):0-0 aheadofprint pubmedlink 33310711 2020 |
Enhancement of amino acid production and secretion by Lactococcus lactis using a droplet-based biosensing and
selection system.
Hernandez-Valdes JA; Aan de Stegge M; Hermans J; Teunis J; van Tatenhove-Pel RJ; Teusink B; Bachmann H;
Kuipers OP
Metab Eng Commun 2020 ;11(0):e00133-0 pubmedlink 32551230 2020 |
Impact of spatial proximity on territoriality among human skin bacteria.
Hernandez-Valdes JA; Zhou L; de Vries MP; Kuipers OP
NPJ Biofilms Microbiomes 2020 ;6(1):30-0 pubmedlink 32764612 2020 |
Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?
Namsolleck P; Moll GN
Mol Med 2020 ;26(1):80-0 pubmedlink 32807075 2020 |
Proton Motive Force Disruptors Block Bacterial Competence and Horizontal Gene Transfer.
Domenech A; Brochado AR; Sender V; Hentrich K; Henriques-Normark B; Typas A; Veening JW
Cell Host Microbe 2020 ;27(4):544-555.e3 pubmedlink 32130952 2020 |
Draft Genome Sequences of Three Amino Acid-Secreting Lactococcus lactis Strains.
Hernandez-Valdes JA; de Jong A; Kok J; Kuipers OP
Microbiol Resour Announc 2020 ;9(16):0-0 pubmedlink 32299876 2020 |
Lysis of a Lactococcus lactis Dipeptidase Mutant and Rescue by Mutation in the Pleiotropic Regulator CodY.
Huang C; Hernandez-Valdes JA; Kuipers OP; Kok J
Appl Environ Microbiol 2020 ;86(8):0-0 pubmedlink 32005740 2020 |
Safety of hospital discharge before return of bowel function after elective colorectal surgery.
Br J Surg 2020 ;107(5):552-559 pubmedlink 31976560 2020 |
Development of Lactococcus lactis Biosensors for Detection of Diacetyl.
Hernandez-Valdes JA; Solopova A; Kuipers OP
Front Microbiol 2020 ;11(0):1032-0 pubmedlink 32523575 2020 |
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus.
Caro-Astorga J; Frenzel E; Perkins JR; Ãlvarez-Mena A; de Vicente A; Ranea JAG; Kuipers OP;
Romero D
NPJ Biofilms Microbiomes 2020 ;6(0):3-0 pubmedlink 31969984 2020 |
Development of Lactococcus lactis Biosensors for Detection of Sulfur-Containing Amino Acids.
Hernandez-Valdes JA; Dalglish MM; Hermans J; Kuipers OP
Front Microbiol 2020 ;11(12):1654-0 pubmedlink 32760389 2020 |
Employing lytic phage-mediated horizontal gene transfer in Lactococcus lactis.
Marcelli B; Karsens H; Nijland M; Oudshoorn R; Kuipers OP; Kok J
PLoS One 2020 ;15(9):e0238988-0 pubmedlink 32925946 2020 |
Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable
Antimicrobials.
Deng J; Viel JH; Kubyshkin V; Budisa N; Kuipers OP
Front Microbiol 2020 ;11(0):575334-0 pubmedlink 33329435 2020 |
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation.
Manago A; Audrito V; Mazzola F; Sorci L; Gaudino F; Gizzi K; Vitale N; Incarnato D; Minazzato G; Ianniello
A; Varriale A; D'Auria S; Mengozzi G; Politano G; Oliviero S; Raffaelli N; Deaglio S
Nat Commun 2019 ;10(1):4116-0 pubmedlink 31511522 2019 |
Multiplexed genome engineering by Cas12a and CRISPR arrays encoded on single transcripts.
Campa CC; Weisbach NR; Santinha AJ; Incarnato D; Platt RJ
Nat Methods 2019 ;16(9):887-893 pubmedlink 31406383 2019 |
Selective Modification of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) through
Diels-Alder Cycloadditions on Dehydroalanine Residues.
de Vries RH; Viel JH; Oudshoorn R; Kuipers OP; Roelfes G
Chemistry 2019 ;25(55):12698-12702 pubmedlink 31361053 2019 |
A Specific Sugar Moiety in the Lactococcus lactis Cell Wall Pellicle Is Required for Infection by CHPC971, a
Member of the Rare 1706 Phage Species.
Marcelli B; de Jong A; Karsens H; Janzen T; Kok J; Kuipers OP
Appl Environ Microbiol 2019 ;85(19):0-0 pubmedlink 31350317 2019 |
Metabolic engineering and synthetic biology employing Lactococcus lactis and Bacillus subtilis cell factories.
van Tilburg AY; Cao H; van der Meulen SB; Solopova A; Kuipers OP
Curr Opin Biotechnol 2019 ;59(0):1-7 pubmedlink 30784872 2019 |
RocS drives chromosome segregation and nucleoid protection in Streptococcus pneumoniae.
Mercy C; Ducret A; Slager J; Lavergne JP; Freton C; Nagarajan SN; Garcia PS; Noirot-Gros MF; Dubarry N;
Nourikyan J; Veening JW; Grangeasse C
Nat Microbiol 2019 ;4(10):1661-1670 pubmedlink 31182798 2019 |
BactMAP: An R package for integrating, analyzing and visualizing bacterial microscopy data.
van Raaphorst R; Kjos M; Veening JW
Mol Microbiol 2019 ;4(10):1661-0 pubmedlink 31693257 2019 |
Cyclic angiotensin-(1-7) contributes to rehabilitation of animal performance in a rat model of cerebral stroke.
Kuipers A; Moll GN; Levy A; Krakovsky M; Franklin R
Peptides 2019 ;123(0):170193-0 pubmedlink 31704212 2019 |
Construction and characterization of a double mutant of Enterococcus faecalis that does not produce biogenic
amines.
Perez M; Calles-Enriquez M; Del Rio B; Redruello B; de Jong A; Kuipers OP; Kok
J; Martin MC; Ladero V; Fernandez M; Alvarez MA
Sci Rep 2019 ;9(1):16881-0 pubmedlink 31727936 2019 |
Phosphosugar Stress in Bacillus subtilis: Intracellular Accumulation of Mannose 6-Phosphate Derepressed the
glcR-phoC Operon from Repression by GlcR.
Morabbi Heravi K; Manzoor I; Watzlawick H; de Jong A; Kuipers OP; Altenbuchner J
J Bacteriol 2019 ;201(9):0-0 pubmedlink 30782637 2019 |
Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale.
Schmitt S; Montalban-Lopez M; Peterhoff D; Deng J; Wagner R; Held M; Kuipers OP; Panke S
Nat Chem Biol 2019 ;15(5):437-443 pubmedlink 30936500 2019 |
Heterologous biosynthesis and characterization of a glycocin from a thermophilic bacterium.
Kaunietis A; Buivydas A; Citavicius DJ; Kuipers OP
Nat Commun 2019 ;10(1):1115-0 pubmedlink 30846700 2019 |
Draft Genome Sequences of 10 Paenibacillus and Bacillus sp. Strains Isolated from Healthy Tomato Plants and
Rhizosphere Soil.
Zhou L; Song C; de Jong A; Kuipers OP
Microbiol Resour Announc 2019 ;8(12):0-0 pubmedlink 30938696 2019 |
Ampicillin-treated Lactococcus lactis MG1363 populations contain persisters as well as viable but non-culturable
cells.
van Tatenhove-Pel RJ; Zwering E; Solopova A; Kuipers OP; Bachmann H
Sci Rep 2019 ;9(1):9867-0 pubmedlink 31285492 2019 |
In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs.
Simon LM; Morandi E; Luganini A; Gribaudo G; Martinez-Sobrido L; Turner DH; Oliviero S; Incarnato D
Nucleic Acids Res 2019 ;47(13):7003-7017 pubmedlink 31053845 2019 |
Genetically Encoded Libraries of Constrained Peptides.
Bosma T; Rink R; Moosmeier MA; Moll GN
Chembiochem 2019 ;20(14):1754-1758 pubmedlink 30794341 2019 |
Refining the Pneumococcal Competence Regulon by RNA Sequencing.
Slager J; Aprianto R; Veening JW
J Bacteriol 2019 ;201(13):0-0 pubmedlink 30885934 2019 |
Engineering Lactococcus lactis for the production of unusual anthocyanins using tea as substrate.
Solopova A; van Tilburg AY; Foito A; Allwood JW; Stewart D; Kulakauskas S; Kuipers OP
Metab Eng 2019 ;54(0):160-169 pubmedlink 30978503 2019 |
Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure
strength.
Price CE; Branco Dos Santos F; Hesseling A; Uusitalo JJ; Bachmann H; Benavente V; Goel A; Berkhout J;
Bruggeman FJ; Marrink SJ; Montalban-Lopez M; de Jong A; Kok J; Molenaar D; Poolman B; Teusink B;
Kuipers OP
BMC Evol Biol 2019 ;19(1):15-0 pubmedlink 30630406 2019 |
Draft Genome Sequences of Six Bacillus Strains and One Brevibacillus Strain Isolated from the Rhizosphere of
Perennial Ryegrass (Lolium perenne).
Li Z; Song C; de Jong A; Kuipers OP
Microbiol Resour Announc 2019 ;8(4):0-0 pubmedlink 30701254 2019 |
Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models.
Kuipers A; Moll GN; Wagner E; Franklin R
Peptides 2019 ;112(0):78-84 pubmedlink 30529303 2019 |
Renaissance of traditional DNA transfer strategies for improvement of industrial lactic acid bacteria.
Bron PA; Marcelli B; Mulder J; van der Els S; Morawska LP; Kuipers OP; Kok J;
Kleerebezem M
Curr Opin Biotechnol 2019 ;56(0):61-68 pubmedlink 30317145 2019 |
Design and Expression of Specific Hybrid Lantibiotics Active Against Pathogenic Clostridium spp.
Cebrian R; Macia-Valero A; Jati AP; Kuipers OP
Front Microbiol 2019 ;10(0):2154-0 pubmedlink 31616392 2019 |
TprA/PhrA Quorum Sensing System Has a Major Effect on Pneumococcal Survival in Respiratory Tract and Blood, and Its
Activity Is Controlled by CcpA and GlnR.
Motib AS; Al-Bayati FAY; Manzoor I; Shafeeq S; Kadam A; Kuipers OP; Hiller NL; Andrew PW;
Yesilkaya H
Front Cell Infect Microbiol 2019 ;9(0):326-0 pubmedlink 31572692 2019 |
Feasability of Introducing a Thioether Ring in Vasopressin by nisBTC Co-expression in Lactococcus lactis.
Li Q; Montalban-Lopez M; Kuipers OP
Front Microbiol 2019 ;10(0):1508-0 pubmedlink 31333616 2019 |
Transcriptional response of Lactococcus lactis during bacterial emulsification.
Tarazanova M; Huppertz T; Starrenburg M; Todt T; van Hijum S; Kok J; Bachmann H
PLoS One 2019 ;14(7):e0220048-0 pubmedlink 31344087 2019 |
Fluorescently Labeled DNA Interacts with Competence and Recombination Proteins and Is Integrated and Expressed
Following Natural Transformation of Bacillus subtilis.
Boonstra M; Vesel N; Kuipers OP
MBio 2018 ;9(5):61-0 pubmedlink 30254116 2018 |
Eavesdropping and crosstalk between secreted quorum sensing peptide signals that regulate bacteriocin production
in Streptococcus pneumoniae.
Miller EL; Kjos M; Abrudan MI; Roberts IS; Veening JW; Rozen DE
ISME J 2018 ;12(10):2363-2375 pubmedlink 29899510 2018 |
Antibiotic-Induced Cell Chaining Triggers Pneumococcal Competence by Reshaping Quorum Sensing to Autocrine-Like
Signaling.
Domenech A; Slager J; Veening JW
Cell Rep 2018 ;25(9):2390-2400.e3 pubmedlink 30485808 2018 |
High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions.
Aprianto R; Slager J; Holsappel S; Veening JW
Nucleic Acids Res 2018 ;46(19):9990-10006 pubmedlink 30165663 2018 |
Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39.
Slager J; Aprianto R; Veening JW
Nucleic Acids Res 2018 ;46(19):9971-9989 pubmedlink 30107613 2018 |
Influence of global gene regulatory networks on single cell heterogeneity of green fluorescent protein production
in Bacillus subtilis.
Cao H; Kuipers OP
Microb Cell Fact 2018 ;17(1):134-0 pubmedlink 30165856 2018 |
Dynamic sporulation gene co-expression networks for Bacillus subtilis 168 and the food-borne isolate Bacillus
amyloliquefaciens: a transcriptomic model.
Omony J; de Jong A; Krawczyk AO; Eijlander RT; Kuipers OP
Microb Genom 2018 ;0(0):0-0 - pubmedlink 29424683 2018 |
Optimized fluorescent proteins for the rhizosphere-associated bacterium Bacillus mycoides with endophytic and
biocontrol agent potential.
Yi Y; Frenzel E; Spoelder J; Elzenga JTM; van Elsas JD; Kuipers OP
Environ Microbiol Rep 2018 ;10(1):57-74 pubmedlink 29195004 2018 |
In vivo selection of sfGFP variants with improved and reliable functionality in industrially important thermophilic
bacteria.
Frenzel E; Legebeke J; van Stralen A; van Kranenburg R; Kuipers OP
Biotechnol Biofuels 2018 ;11(0):8-0 pubmedlink 29371884 2018 |
Stress response of a clinical Enterococcus faecalis isolate subjected to a novel antimicrobial surface coating.
Clauss-Lendzian E; Vaishampayan A; de Jong A; Landau U; Meyer C; Kok J; Grohmann E
Microbiol Res 2018 ;207(0):53-64 pubmedlink 29458868 2018 |
Interplay Between Capsule Expression and Uracil Metabolism in Streptococcus pneumoniae D39.
Carvalho SM; Kloosterman TG; Manzoor I; Caldas J; Vinga S; Martinussen J; Saraiva LM;
Kuipers OP; Neves AR
Front Microbiol 2018 ;9(0):321-0 pubmedlink 29599757 2018 |
A Novel Antimicrobial Coating Represses Biofilm and Virulence-Related Genes in Methicillin-Resistant Staphylococcus
aureus.
Vaishampayan A; de Jong A; Wight DJ; Kok J; Grohmann E
Front Microbiol 2018 ;9(0):221-0 pubmedlink 29497410 2018 |
Specificity and Application of the Lantibiotic Protease NisP.
Montalban-Lopez M; Deng J; van Heel AJ; Kuipers OP
Front Microbiol 2018 ;9(0):160-0 pubmedlink 29479343 2018 |
Heterologous signal peptides-directing secretion of Streptomyces mobaraensis transglutaminase by Bacillus subtilis.
Mu D; Lu J; Qiao M; Kuipers OP; Zhu J; Li X; Yang P; Zhao Y; Luo S; Wu X; Jiang S; Zheng Z
Appl Microbiol Biotechnol 2018 ;0(0):0-0 - pubmedlink 29691630 2018 |
Rgg-Shp regulators are important for pneumococcal colonization and invasion through their effect on mannose
utilization and capsule synthesis.
Zhi X; Abdullah IT; Gazioglu O; Manzoor I; Shafeeq S; Kuipers OP; Hiller NL; Andrew PW;
Yesilkaya H
Sci Rep 2018 ;8(1):6369-0 pubmedlink 29686372 2018 |
Expanding the Genetic Code of Lactococcus lactis and Escherichia coli to Incorporate Non-canonical Amino Acids for
Production of Modified Lantibiotics.
Bartholomae M; Baumann T; Nickling JH; Peterhoff D; Wagner R; Budisa N; Kuipers OP
Front Microbiol 2018 ;9(0):657-0 pubmedlink 29681891 2018 |
Co-expression of Nisin Z and Leucocin C as a Basis for Effective Protection Against Listeria monocytogenes in
Pasteurized Milk.
Fu Y; Mu D; Qiao W; Zhu D; Wang X; Liu F; Xu H; Saris P; Kuipers OP; Qiao M
Front Microbiol 2018 ;9(0):547-0 pubmedlink 29628920 2018 |
Increasing Antimicrobial Activity of Nisin-based Lantibiotics Against Gram-negative Pathogens.
Li Q; Montalban-Lopez M; Kuipers OP
Appl Environ Microbiol 2018 ;0(0):0-0 - pubmedlink 29625984 2018 |
Boosting heterologous protein production yield by adjusting global nitrogen and carbon metabolic regulatory
networks in Bacillus subtilis.
Cao H; Villatoro-Hernandez J; Weme RDO; Frenzel E; Kuipers OP
Metab Eng 2018 ;0(0):0-0 - pubmedlink 30096425 2018 |
Exploring plant-microbe interactions of the rhizobacteria Bacillus subtilis and Bacillus mycoides by use of the
CRISPR-Cas9 system.
Yi Y; Li Z; Song C; Kuipers OP
Environ Microbiol 2018 ;0(0):0-0 - pubmedlink 30051589 2018 |
Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to
thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure.
Siroli L; Braschi G; de Jong A; Kok J; Patrignani F; Lanciotti R
J Appl Microbiol 2018 ;0(0):0-0 - pubmedlink 30028070 2018 |
Plant-Microbe Interaction: Transcriptional Response of Bacillus Mycoides to Potato Root Exudates.
Yi Y; Li Z; Kuipers OP
J Vis Exp 2018 ;0(137):0-0 - pubmedlink 30010657 2018 |
BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins.
van Heel AJ; de Jong A; Song C; Viel JH; Kok J; Kuipers OP
Nucleic Acids Res 2018 ;46(0):0-0 pubmedlink 29788290 2018 |
Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids.
Nickling JH; Baumann T; Schmitt FJ; Bartholomae M; Kuipers OP; Friedrich T; Budisa N
J Vis Exp 2018 ;0(135):0-0 - pubmedlink 29781997 2018 |
Altering textural properties of fermented milk by using surface-engineered Lactococcus lactis.
Tarazanova M; Huppertz T; Kok J; Bachmann H
Microb Biotechnol 2018 ;11(4):770-780 pubmedlink 29745037 2018 |
Further Elucidation of Galactose Utilization in Lactococcus lactis MG1363.
Solopova A; Bachmann H; Teusink B; Kok J; Kuipers OP
Front Microbiol 2018 ;9(0):1803-0 pubmedlink 30123211 2018 |
NADH-Mediated Gene Expression in Streptococcus pneumoniae and Role of Rex as a Transcriptional Repressor of the
Rex-Regulon.
Afzal M; Shafeeq S; Kuipers OP
Front Microbiol 2018 ;9(137):1300-0 pubmedlink 29971050 2018 |
On the efficient bio-incorporation of 5-hydroxy-tryptophan in recombinant proteins expressed in Escherichia coli
with T7 RNA polymerase-based vectors.
Oliveira-Souza WP; Bronze F; Broos J; Marcondes MFM; Oliveira V
Biochem Biophys Res Commun 2017 ;492(3):343-348 pubmedlink 28859987 2017 |
Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein.
Urban JH; Moosmeier MA; Aumuller T; Thein M; Bosma T; Rink R; Groth K; Zulley M; Siegers K; Tissot K; Moll
GN; Prassler J
Nat Commun 2017 ;8(1):1500-0 pubmedlink 29138389 2017 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Kuipers A; de Vries L; de Vries MP; Rink R; Bosma T; Moll GN
Peptides 2017 ;91(0):33-39 pubmedlink 28300673 2017 |
Cell Surface Properties of Lactococcus lactis Reveal Milk Protein Binding Specifically Evolved in Dairy Isolates.
Tarazanova M; Huppertz T; Beerthuyzen M; van Schalkwijk S; Janssen P; Wels M; Kok J; Bachmann H
Front Microbiol 2017 ;8(0):1691-0 pubmedlink 28936202 2017 |
Disruption of a transcriptional repressor by an IS-element integration leads to the activation of a novel silent
cellobiose transporter in Lactococcus lactis MG1363.
Solopova A; Kok J; Kuipers OP
Appl Environ Microbiol 2017 ;0(0):0-0 - pubmedlink 28970222 2017 |
Genome-guided identification of novel head-to-tail cyclized antimicrobial peptides, exemplified by the discovery of
pumilarin.
van Heel AJ; Montalban-Lopez M; Oliveau Q; Kuipers OP
Microb Genom 2017 ;3(10):0-0 pubmedlink 29177092 2017 |
Early Transcriptome Response of Lactococcus lactis to Environmental Stresses Reveals Differentially Expressed Small
Regulatory RNAs and tRNAs.
van der Meulen SB; de Jong A; Kok J
Front Microbiol 2017 ;8(0):1704-0 pubmedlink 28959239 2017 |
Major gene-regulatory mechanisms operating in ribosomally synthesized and post-translationally modified peptide
(RiPP) biosynthesis.
Bartholomae M; Buivydas A; Viel JH; Montalban-Lopez M; Kuipers OP
Mol Microbiol 2017 ;0(0):0-0 - pubmedlink 28787536 2017 |
Comparative Transcriptomics of Bacillus mycoides Strains in Response to Potato-Root Exudates Reveals Different
Genetic Adaptation of Endophytic and Soil Isolates.
Yi Y; de Jong A; Frenzel E; Kuipers OP
Front Microbiol 2017 ;8(0):1487-0 pubmedlink 28824604 2017 |
Unleashing natural competence in Lactococcus lactis by induction of the competence regulator ComX.
Mulder J; Wels M; Kuipers OP; Kleerebezem M; Bron PA
Appl Environ Microbiol 2017 ;0(0):0-0 - pubmedlink 28778888 2017 |
Editorial: Lactic acid bacteria-a continuing journey in science and application.
Kleerebezem M; Kuipers OP; Smid EJ
FEMS Microbiol Rev 2017 ;41(0):0-0 pubmedlink 28830097 2017 |
The Evolution of gene regulation research in Lactococcus lactis.
Kok J; van Gijtenbeek LA; de Jong A; van der Meulen SB; Solopova A; Kuipers
OP
FEMS Microbiol Rev 2017 ;41(0):0-0 pubmedlink 28830093 2017 |
Chromosome segregation drives division site selection in Streptococcus pneumoniae.
van Raaphorst R; Kjos M; Veening JW
Proc Natl Acad Sci U S A 2017 ;114(29):0-0 pubmedlink 28674002 2017 |
The Staphylococcus aureus alpha-Acetolactate Synthase ALS Confers Resistance to Nitrosative Stress.
Carvalho SM; de Jong A; Kloosterman TG; Kuipers OP; Saraiva LM
Front Microbiol 2017 ;8(0):1273-0 pubmedlink 28744267 2017 |
Illuminating Messengers: An Update and Outlook on RNA Visualization in Bacteria.
van Gijtenbeek LA; Kok J
Front Microbiol 2017 ;8(0):1161-0 pubmedlink 28690601 2017 |
CodY Regulates Thiol Peroxidase Expression as Part of the Pneumococcal Defense Mechanism against H2O2 Stress.
Hajaj B; Yesilkaya H; Shafeeq S; Zhi X; Benisty R; Tchalah S; Kuipers OP; Porat N
Front Cell Infect Microbiol 2017 ;7(0):210-0 pubmedlink 28596944 2017 |
Transcriptome analysis shows activation of the arginine deiminase pathway in Lactococcus lactis as a response to
ethanol stress.
Diez L; Solopova A; Fernandez-Perez R; Gonzalez M; Tenorio C; Kuipers OP; Ruiz-Larrea F
Int J Food Microbiol 2017 ;257(0):41-48 pubmedlink 28644989 2017 |
CodY Regulates Thiol Peroxidase Expression as Part of the Pneumococcal Defense Mechanism against H2O2 Stress.
Hajaj B; Yesilkaya H; Shafeeq S; Zhi X; Benisty R; Tchalah S; Kuipers OP; Porat N
Front Cell Infect Microbiol 2017 ;7(0):210-0 pubmedlink 28596944 2017 |
High-throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae.
Liu X; Gallay C; Kjos M; Domenech A; Slager J; van Kessel SP; Knoops K;
Sorg RA; Zhang JR; Veening JW
Mol Syst Biol 2017 ;13(5):931-0 pubmedlink 28490437 2017 |
Mining prokaryotes for antimicrobial compounds: from diversity to function.
Tracanna V; de Jong A; Medema MH; Kuipers OP
FEMS Microbiol Rev 2017 ;41(3):417-429 pubmedlink 28402441 2017 |
Editorial: Bacterial pathogens, antibiotics and antibiotic resistance.
Banin E; Hughes D; Kuipers OP
FEMS Microbiol Rev 2017 ;41(3):450-452 pubmedlink 28486583 2017 |
Cell surface engineering of Bacillus subtilis improves production yields of heterologously expressed
alpha-amylases.
Cao H; van Heel AJ; Ahmed H; Mols M; Kuipers OP
Microb Cell Fact 2017 ;16(1):56-0 pubmedlink 28376879 2017 |
Pentapeptide-rich peptidoglycan at the Bacillus subtilis cell-division site.
Morales Angeles D; Liu Y; Hartman AM; Borisova M; de Sousa Borges A; de Kok N; Beilharz K; Veening
JW; Mayer C; Hirsch AK; Scheffers DJ
Mol Microbiol 2017 ;104(2):319-333 pubmedlink 28118510 2017 |
Niacin-mediated Gene Expression and Role of NiaR as a Transcriptional Repressor of niaX, nadC, and pnuC in
Streptococcus pneumoniae.
Afzal M; Kuipers OP; Shafeeq S
Front Cell Infect Microbiol 2017 ;7(0):70-0 pubmedlink 28337428 2017 |
Spore Heat Activation Requirements and Germination Responses Correlate with Sequences of Germinant Receptors and
with the Presence of a Specific spoVA2mob Operon in Foodborne Strains of Bacillus subtilis.
Krawczyk AO; de Jong A; Omony J; Holsappel S; Wells-Bennik MH; Kuipers OP; Eijlander
RT
Appl Environ Microbiol 2017 ;83(7):0-0 pubmedlink 28130296 2017 |
Pneumococcal galactose catabolism is controlled by multiple regulators acting on pyruvate formate lyase.
Al-Bayati FA; Kahya HF; Damianou A; Shafeeq S; Kuipers OP; Andrew PW; Yesilkaya H
Sci Rep 2017 ;7(0):43587-0 pubmedlink 28240278 2017 |
Prospects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial
Peptides.
Baumann T; Nickling JH; Bartholomae M; Buivydas A; Kuipers OP; Budisa N
Front Microbiol 2017 ;8(0):124-0 pubmedlink 28210246 2017 |
Expression of prophage-encoded endolysins contributes to autolysis of Lactococcus lactis.
Visweswaran GR; Kurek D; Szeliga M; Pastrana FR; Kuipers OP; Kok J; Buist G
Appl Microbiol Biotechnol 2017 ;101(3):1099-1110 pubmedlink 27660179 2017 |
From Cell Death to Metabolism: Holin-Antiholin Homologues with New Functions.
van den Esker MH; Kovacs AT; Kuipers OP
MBio 2017 ;8(6):0-0 pubmedlink 29208748 2017 |
The Relationship among Tyrosine Decarboxylase and Agmatine Deiminase Pathways in Enterococcus faecalis.
Perez M; Ladero V; Del Rio B; Redruello B; de Jong A; Kuipers O; Kok J; Martin
MC; Fernandez M; Alvarez MA
Front Microbiol 2017 ;8(0):2107-0 pubmedlink 29163401 2017 |
Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins.
Dockerty P; Edens JG; Tol MB; Morales Angeles D; Domenech A; Liu Y; Hirsch AK; Veening JW; Scheffers
DJ; Witte MD
Org Biomol Chem 2017 ;15(4):894-910 pubmedlink 28045164 2017 |
Bacteriocins of lactic acid bacteria: extending the family.
Alvarez-Sieiro P; Montalbán-López M; Mu D; Kuipers OP
Appl Microbiol Biotechnol 2016 ;100(7):2939-51 pubmedlink 26860942 2016 |
Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during
early infection.
Aprianto R; Slager J; Holsappel S; Veening JW
Genome Biol 2016 ;17(1):198-0 pubmedlink 27678244 2016 |
Expression of prophage-encoded endolysins contributes to autolysis of Lactococcus lactis.
Visweswaran GR; Kurek D; Szeliga M; Pastrana FR; Kuipers OP; Kok J; Buist G
Appl Microbiol Biotechnol 2016 ;0(0):0-0 - pubmedlink 27660179 2016 |
Employing the promiscuity of lantibiotic biosynthetic machineries to produce novel antimicrobials.
Montalban-Lopez M; van Heel AJ; Kuipers OP
FEMS Microbiol Rev 2016 ;0(0):0-0 - pubmedlink 27591436 2016 |
N-acetylgalatosamine-Mediated Regulation of the aga Operon by AgaR in Streptococcus pneumoniae.
Afzal M; Shafeeq S; Ahmed H; Kuipers OP
Front Cell Infect Microbiol 2016 ;6(0):101-0 pubmedlink 27672623 2016 |
A putative amino acid transporter determines sensitivity to the two-peptide bacteriocin plantaricin JK.
Oppegard C; Kjos M; Veening JW; Nissen-Meyer J; Kristensen T
Microbiologyopen 2016 ;5(4):700-8 pubmedlink 27150273 2016 |
Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal
meningitis model.
Jim KK; Engelen-Lee J; van der Sar AM; Bitter W; Brouwer MC; van der Ende A; Veening JW; van de Beek D;
Vandenbroucke-Grauls CM
J Neuroinflammation 2016 ;13(1):188-0 pubmedlink 27542968 2016 |
Discovery, Production and Modification of Five Novel Lantibiotics Using the Promiscuous Nisin Modification
Machinery.
van Heel AJ; Kloosterman TG; Montalban-Lopez M; Deng J; Plat A; Baudu B;
Hendriks D; Moll GN; Kuipers OP
ACS Synth Biol 2016 ;0(0):0-0 - pubmedlink 27294279 2016 |
Stress Physiology of Lactic Acid Bacteria.
Papadimitriou K; Alegria A; Bron PA; de Angelis M; Gobbetti M; Kleerebezem M; Lemos JA; Linares DM; Ross P; Stanton
C; Turroni F; van Sinderen D; Varmanen P; Ventura M; Zuniga M; Tsakalidou E; Kok J
Microbiol Mol Biol Rev 2016 ;80(3):837-90 pubmedlink 27466284 2016 |
YsbA and LytST are essential for pyruvate utilization in Bacillus subtilis.
van den Esker MH; Kovacs AT; Kuipers OP
Environ Microbiol 2016 ;0(0):0-0 - pubmedlink 27422364 2016 |
Linking Bacillus cereus Genotypes and Carbohydrate Utilization Capacity.
Warda AK; Siezen RJ; Boekhorst J; Wells-Bennik MH; de Jong A; Kuipers OP; Nierop Groot MN; Abee T
PLoS One 2016 ;11(6):0-0 pubmedlink 27272929 2016 |
The impact of manganese on biofilm development of Bacillus subtilis.
Mhatre E; Troszok A; Gallegos-Monterrosa R; Lindstadt S; Holscher T; Kuipers OP; Kovacs AT
Microbiology 2016 ;0(0):0-0 - pubmedlink 27267987 2016 |
Hard-Wired Control of Bacterial Processes by Chromosomal Gene Location.
Slager J; Veening JW
Trends Microbiol 2016 ;0(0):0-0 - pubmedlink 27364121 2016 |
Transcriptome profiling of TDC cluster deletion mutant of Enterococcus faecalis V583.
Perez M; Ladero V; Del Rio B; Redruello B; de Jong A; Kuipers OP; Kok J; Martin
MC; Fernandez M; Alvarez MA
Genom Data 2016 ;9(0):67-9 pubmedlink 27408815 2016 |
Draft Whole-Genome Sequences of 11 Bacillus cereus Food Isolates.
Hayrapetyan H; Boekhorst J; de Jong A; Kuipers OP; Nierop Groot MN; Abee T
Genome Announc 2016 ;4(3):0-0 pubmedlink 27257202 2016 |
Draft Whole-Genome Sequences of Three Lactobacillus plantarum Food Isolates.
Fernandez Ramirez MD; Boekhorst J; de Jong A; Kuipers OP; Abee T; Nierop Groot MN
Genome Announc 2016 ;4(3):0-0 pubmedlink 27313301 2016 |
Draft Genome Sequences of Seven Thermophilic Spore-Forming Bacteria Isolated from Foods That Produce Highly
Heat-Resistant Spores, Comprising Geobacillus spp., Caldibacillus debilis, and Anoxybacillus flavithermus.
Berendsen EM; Wells-Bennik MH; Krawczyk AO; de Jong A; van Heel A; Holsappel S;
Eijlander RT; Kuipers OP
Genome Announc 2016 ;4(3):0-0 pubmedlink 27151781 2016 |
A transposon present in specific strains of Bacillus subtilis negatively affects nutr
Krawczyk AO; Berendsen EM; de Jong A; Boekhorst J; Wells-Bennik MH; Kuipers OP; Eijlander
RT
Environ Microbiol 2016 ;0(0):0-0 - pubmedlink 27234229 2016 |
Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis.
Solopova A; Formosa-Dague C; Courtin P; Furlan S; Veiga P; Pechoux C; Armalyte J; Sadauskas M;
Kok J; Hols P; Dufrene YF; Kuipers OP; Chapot-Chartier MP; Kulakauskas S
J Biol Chem 2016 ;291(21):11323-36 pubmedlink 27022026 2016 |
Genome Sequences of 12 Spore-Forming Bacillus Species, Comprising Bacillus coagulans, Bacillus licheniformis,
Bacillus amyloliquefaciens, Bacillus sporothermodurans, and Bacillus vallismortis, Isolated from Foods.
Krawczyk AO; de Jong A; Holsappel S; Eijlander RT; van Heel A; Berendsen EM;
Wells-Bennik MH; Kuipers OP
Genome Announc 2016 ;4(3):0-0 pubmedlink 27174261 2016 |
A mobile genetic element profoundly increases heat resistance of bacterial spores.
Berendsen EM; Boekhorst J; Kuipers OP; Wells-Bennik MH
ISME J 2016 ;10(11):2633-2642 pubmedlink 27105070 2016 |
Transcriptome landscape of Lactococcus lactis reveals many novel RNAs including a small regulatory RNA involved in
carbon uptake and metabolism.
van der Meulen SB; de Jong A; Kok J
RNA Biol 2016 ;13(3):353-66 pubmedlink 26950529 2016 |
Posttranslational Peptide-Modification Enzymes in Action: Key Roles for Leaders and Glutamate.
Montalban-Lopez M; Kuipers OP
Cell Chem Biol 2016 ;23(3):318-9 pubmedlink 26991100 2016 |
Development of an efficient electroporation method for rhizobacterial Bacillus mycoides strains.
Yi Y; Kuipers OP
J Microbiol Methods 2016 ;133(0):82-86 pubmedlink 28042055 2016 |
Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation.
Sorg RA; Lin L; van Doorn GS; Sorg M; Olson J; Nizet V; Veening JW
PLoS Biol 2016 ;14(12):0-0 pubmedlink 28027306 2016 |
High-Level Heat Resistance of Spores of Bacillus amyloliquefaciens and Bacillus licheniformis Results from the
Presence of a spoVA Operon in a Tn1546 Transposon.
Berendsen EM; Koning RA; Boekhorst J; de Jong A; Kuipers OP; Wells-Bennik MH
Front Microbiol 2016 ;7(0):1912-0 pubmedlink 27994575 2016 |
On the Spatial Organization of mRNA, Plasmids, and Ribosomes in a Bacterial Host Overexpressing Membrane Proteins.
van Gijtenbeek LA; Robinson A; van Oijen AM; Poolman B; Kok J
PLoS Genet 2016 ;12(12):0-0 pubmedlink 27977669 2016 |
Plasmid Complement of Lactococcus lactis NCDO712 Reveals a Novel Pilus Gene Cluster.
Tarazanova M; Beerthuyzen M; Siezen R; Fernandez-Gutierrez MM; de Jong A; van der Meulen S; Kok
J; Bachmann H
PLoS One 2016 ;11(12):0-0 pubmedlink 27941999 2016 |
Cysteine-Mediated Gene Expression and Characterization of the CmbR Regulon in Streptococcus pneumoniae.
Afzal M; Manzoor I; Kuipers OP; Shafeeq S
Front Microbiol 2016 ;7(0):1929-0 pubmedlink 27990139 2016 |
Identification and classification of known and putative antimicrobial compounds produced by a wide variety of
Bacillales species.
Zhao X; Kuipers OP
BMC Genomics 2016 ;17(1):882-0 pubmedlink 27821051 2016 |
Identification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity
Environments Using RNA Sequencing.
Nagler K; Krawczyk AO; De Jong A; Madela K; Hoffmann T; Laue M; Kuipers OP; Bremer E; Moeller R
Front Microbiol 2016 ;7(0):1564-0 pubmedlink 27766092 2016 |
Methionine-mediated gene expression and characterization of the CmhR regulon in Streptococcus pneumoniae.
Afzal M; Shafeeq S; Kuipers OP
Microb Genom 2016 ;2(10):0-0 pubmedlink 28348831 2016 |
Methionine-mediated gene expression and characterization of the CmhR regulon in Streptococcus pneumoniae.
Afzal M; Shafeeq S; Kuipers OP
Microb Genom 2016 ;2(10):0-0 pubmedlink 28348831 2016 |
Draft Genome Sequences of Two Geobacillus Species Strains, Isolated from Oil Wells and Surface Soil above Oil
Pools.
Kaunietis A; de Jong A; Pranckute R; Buivydas A; Kuipers OP
Genome Announc 2016 ;4(5):0-0 pubmedlink 27795271 2016 |
SpoVT: From Fine-Tuning Regulator in Bacillus subtilis to Essential Sporulation Protein in Bacillus cereus.
Eijlander RT; Holsappel S; de Jong A; Ghosh A; Christie G; Kuipers OP
Front Microbiol 2016 ;7(0):1607-0 pubmedlink 27790204 2016 |
Transcriptome analysis of Streptococcus pneumoniae D39 in the presence of cobalt.
Manzoor I; Shafeeq S; Kuipers OP
Genom Data 2015 ;6(0):151-3 pubmedlink 26697359 2015 |
T-REx: Transcriptome analysis webserver for RNA-seq Expression data.
de Jong A; van der Meulen S; Kuipers OP; Kok J
BMC Genomics 2015 ;16(0):663-0 pubmedlink 26335208 2015 |
What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory
systems.
Bhogale PM; Sorg RA; Veening JW; Berg J
Nucleic Acids Res 2015 ;42(18):11321-8 pubmedlink 25245949 2015 |
Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in
Streptococcus pneumoniae.
Nourikyan J; Kjos M; Mercy C; Cluzel C; Morlot C; Noirot-Gros MF; Guiral S; Lavergne JP; Veening JW;
Grangeasse C
PLoS Genet 2015 ;11(9):0-0 pubmedlink 26378458 2015 |
Minimum Information about a Biosynthetic Gene cluster.
Medema MH; Kottmann R; Yilmaz P; Cummings M; Biggins JB; Blin K; de Bruijn I; Chooi YH; Claesen J; Coates
RC; Cruz-Morales P; Duddela S; Dusterhus S; Edwards DJ; Fewer DP; Garg N; Geiger C; Gomez-Escribano JP; Greule A;
Hadjithomas M; Haines AS; Helfrich EJ; Hillwig ML; Ishida K; Jones AC; Jones CS; Jungmann K; Kegler C; Kim HU;
Kotter P; Krug D; Masschelein J; Melnik AV; Mantovani SM; Monroe EA; Moore M; Moss N; Nutzmann HW; Pan G; Pati A;
Petras D; Reen FJ; Rosconi F; Rui Z; Tian Z; Tobias NJ; Tsunematsu Y; Wiemann P; Wyckoff E; Yan X; Yim G; Yu F; Xie
Y; Aigle B; Apel AK; Balibar CJ; Balskus EP; Barona-Gomez F; Bechthold A; Bode HB; Borriss R; Brady SF; Brakhage
AA; Caffrey P; Cheng YQ; Clardy J; Cox RJ; De Mot R; Donadio S; Donia MS; van der Donk WA; Dorrestein PC; Doyle S;
Driessen AJ; Ehling-Schulz M; Entian KD; Fischbach MA; Gerwick L; Gerwick WH; Gross H; Gust B; Hertweck C; Hofte M;
Jensen SE; Ju J; Katz L; Kaysser L; Klassen JL; Keller NP; Kormanec J; Kuipers OP; Kuzuyama T; Kyrpides NC;
Kwon HJ; Lautru S; Lavigne R; Lee CY; Linquan B; Liu X; Liu W; Luzhetskyy A; Mahmud T; Mast Y; Mendez C;
Metsa-Ketela M; Micklefield J; Mitchell DA; Moore BS; Moreira LM; Muller R; Neilan BA; Nett M; Nielsen J; O
Nat Chem Biol 2015 ;11(9):625-31 pubmedlink 26284661 2015 |
Red fluorescent proteins for gene expression and protein localization studies in Streptococcus pneumoniae and
efficient transformation with Gibson assembled DNA.
Beilharz K; van Raaphorst R; Kjos M; Veening JW
Appl Environ Microbiol 2015 ;0(0):0-0 - pubmedlink 26253684 2015 |
Fucose-Mediated Transcriptional Activation of the fcs Operon by FcsR in Streptococcus pneumoniae.
Manzoor I; Shafeeq S; Afzal M; Kuipers OP
J Mol Microbiol Biotechnol 2015 ;25(2):120-8 pubmedlink 26159073 2015 |
A Duo of Potassium-Responsive Histidine Kinases Govern the Multicellular Destiny of Bacillus subtilis.
Grau RR; de Ona P; Kunert M; Lenini C; Gallegos-Monterrosa R; Mhatre E; Vileta D; Donato V; Holscher T; Boland W;
Kuipers OP; Kovacs AT
MBio 2015 ;6(4):0-0 pubmedlink 26152584 2015 |
Recombinant pediocin in Lactococcus lactis: increased production by propeptide fusion and improved potency by
co-production with PedC.
Back A; Borges F; Mangavel C; Paris C; Rondags E; Kapel R; Aymes A; Rogniaux H; Pavlovic M; van Heel AJ;
Kuipers OP; Revol-Junelles AM; Cailliez-Grimal C
Microb Biotechnol 2015 ;0(0):0-0 - pubmedlink 26147827 2015 |
Co(2+)-dependent gene expression in Streptococcus pneumoniae: opposite effect of Mn(2+) and Co(2+) on the
expression of the virulence genes psaBCA, pcpA, and prtA.
Manzoor I; Shafeeq S; Kloosterman TG; Kuipers OP
Front Microbiol 2015 ;6(0):748-0 pubmedlink 26257722 2015 |
Physiological and transcriptional responses of different industrial microbes at near-zero specific growth rates.
Ercan O; Bisschops MM; Overkamp W; Jorgensen TR; Ram AF; Smid EJ; Pronk JT; Kuipers OP;
Daran-Lapujade P; Kleerebezem M
Appl Environ Microbiol 2015 ;0(0):0-0 - pubmedlink 26048933 2015 |
The ParB-parS Chromosome Segregation System Modulates Competence Development in Streptococcus pneumoniae.
Attaiech L; Minnen A; Kjos M; Gruber S; Veening JW
MBio 2015 ;6(4):0-0 pubmedlink 26126852 2015 |
AguR is a transmembrane transcription activator of the putrescine biosynthesis operon in Lactococcus lactis, and
acts in response to agmatine concentration.
Linares DM; Del Rio B; Redruello B; Ladero V; Martin MC; de Jong A; Kuipers OP; Fernandez
M; Alvarez MA
Appl Environ Microbiol 2015 ;0(0):0-0 - pubmedlink 26116671 2015 |
Maltose-Dependent Transcriptional Regulation of the mal Regulon by MalR in Streptococcus pneumoniae.
Afzal M; Shafeeq S; Manzoor I; Kuipers OP
PLoS One 2015 ;10(6):0-0 pubmedlink 26030923 2015 |
Lantibiotic Reductase LtnJ Substrate Selectivity Assessed with a Collection of Nisin Derivatives as Substrates.
Mu D; Montalban-Lopez M; Deng J; Kuipers OP
Appl Environ Microbiol 2015 ;81(11):3679-87 pubmedlink 25795677 2015 |
Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein
investment explain an anaerobic bacterial Crabtree effect?
Goel A; Eckhardt TH; Puri P; de Jong A; Branco Dos Santos F; Giera M; Fusetti F; de Vos WM; Kok
J; Poolman B; Molenaar D; Kuipers OP; Teusink B
Mol Microbiol 2015 ;97(1):77-92 pubmedlink 25828364 2015 |
Microbial bet-hedging: the power of being different.
Grimbergen AJ; Siebring J; Solopova A; Kuipers OP
Curr Opin Microbiol 2015 ;25(0):67-72 pubmedlink 26025019 2015 |
A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in
Streptococcus pneumoniae.
Afzal M; Manzoor I; Kuipers OP
J Vis Exp 2015 ;0(98):0-0 - pubmedlink 25938895 2015 |
Spatio-temporal remodeling of functional membrane microdomains organizes the signaling networks of a bacterium.
Schneider J; Klein T; Mielich-Suss B; Koch G; Franke C; Kuipers OP; Kovacs AT; Sauer M; Lopez D
PLoS Genet 2015 ;11(4):0-0 pubmedlink 25909364 2015 |
Single cell FRET analysis for the identification of optimal FRET-pairs in Bacillus subtilis using a prototype
MEM-FLIM system.
Detert Oude Weme RG; Kovacs AT; de Jong SJ; Veening JW; Siebring J; Kuipers OP
PLoS One 2015 ;10(4):0-0 pubmedlink 25886351 2015 |
Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae.
Shafeeq S; Afzal M; Henriques-Normark B; Kuipers OP
Genom Data 2015 ;4(0):57-9 pubmedlink 26484177 2015 |
Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and
Infection.
Paixao L; Oliveira J; Verissimo A; Vinga S; Lourenco EC; Ventura MR; Kjos M; Veening JW; Fernandes
VE; Andrew PW; Yesilkaya H; Neves AR
PLoS One 2015 ;10(3):0-0 pubmedlink 25826206 2015 |
Draft Genome Sequences of Four Bacillus thermoamylovorans Strains Isolated from Milk and Acacia Gum, a Food
Ingredient.
Krawczyk AO; Berendsen EM; Eijlander RT; de Jong A; Wells-Bennik MH; Kuipers OP
Genome Announc 2015 ;3(2):0-0 pubmedlink 25814599 2015 |
Substrate selectivity of the lantibiotic reductase LtnJ assessed by a collection of nisin derivatives as
substrate.
Mu D; Montalban-Lopez M; Deng J; Kuipers OP
Appl Environ Microbiol 2015 ;0(0):0-0 - pubmedlink 25795677 2015 |
Draft Genome Sequences of Five Spore-Forming Food Isolates of Bacillus pumilus.
de Jong A; van Heel AJ; Montalban-Lopez M; Krawczyk AO; Berendsen EM; Wells-Bennik M;
Kuipers OP
Genome Announc 2015 ;3(2):0-0 pubmedlink 25767247 2015 |
Complete Genome Sequence of Bacillus amyloliquefaciens Strain BH072, Isolated from Honey.
Zhao X; de Jong A; Zhou Z; Kuipers OP
Genome Announc 2015 ;3(2):0-0 pubmedlink 25767235 2015 |
Sialic acid-mediated gene expression in Streptococcus pneumoniae and the role of NanR as a transcriptional
activator of the nan gene cluster.
Afzal M; Shafeeq S; Ahmed H; Kuipers OP
Appl Environ Microbiol 2015 ;0(0):0-0 - pubmedlink 25724955 2015 |
Identification of essential amino acid residues in the nisin dehydratase NisB.
Khusainov R; van Heel AJ; Lubelski J; Moll GN; Kuipers OP
Front Microbiol 2015 ;6(0):102-0 pubmedlink 25767464 2015 |
Ascorbic acid-dependent gene expression in Streptococcus pneumoniae and the activator function of the
transcriptional regulator UlaR2.
Afzal M; Shafeeq S; Kuipers OP
Front Microbiol 2015 ;6(0):72-0 pubmedlink 25717320 2015 |
To mutate or not to mutate: Genetic and epigenetic heterogeneity contribute to bacterial adaptation (comment on DOI
10.1002/bies.201400153).
Veening JW
Bioessays 2015 ;37(2):116-7 pubmedlink 25546613 2015 |
Two distinct groups within the Bacillus subtilis group display significantly different spore heat resistance
properties.
Berendsen EM; Zwietering MH; Kuipers OP; Wells-Bennik MH
Food Microbiol 2015 ;45(0):18-25 pubmedlink 25481058 2015 |
The Regulation of the AdcR Regulon in Streptococcus pneumoniae Depends Both on Zn
Manzoor I; Shafeeq S; Afzal M; Kuipers OP
Front Cell Infect Microbiol 2015 ;5(0):91-0 pubmedlink 26697415 2015 |
A fluorescence-based bioassay for antibacterials and its application in screening natural product extracts.
Michels K; Heinke R; Schone P; Kuipers OP; Arnold N; Wessjohann LA
J Antibiot (Tokyo) 2015 ;68(12):734-40 pubmedlink 26152282 2015 |
Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae.
Kuipers K; Gallay C; Martinek V; Rohde M; Martinkova M; van der Beek SL; Jong WS; Venselaar H; Zomer
A; Bootsma H; Veening JW; de Jonge MI
Mol Microbiol 2015 ;0(0):0-0 - pubmedlink 26691161 2015 |
Next-Generation Whole-Genome Sequencing of Eight Strains of Bacillus cereus, Isolated from Food.
Krawczyk AO; de Jong A; Eijlander RT; Berendsen EM; Holsappel S; Wells-Bennik MH;
Kuipers OP
Genome Announc 2015 ;3(6):0-0 pubmedlink 26679589 2015 |
GalR Acts as a Transcriptional Activator of galKT in the Presence of Galactose in Streptococcus pneumoniae.
Afzal M; Shafeeq S; Manzoor I; Kuipers OP
J Mol Microbiol Biotechnol 2015 ;25(6):363-371 pubmedlink 26544195 2015 |
Bacillus thermoamylovorans Spores with Very-High-Level Heat Resistance Germinate Poorly in Rich Medium despite the
Presence of ger Clusters but Efficiently upon Exposure to Calcium-Dipicolinic Acid.
Berendsen EM; Krawczyk AO; Klaus V; de Jong A; Boekhorst J; Eijlander RT; Kuipers OP;
Wells-Bennik MH
Appl Environ Microbiol 2015 ;81(22):7791-801 pubmedlink 26341201 2015 |
Ni2+-Dependent and PsaR-Mediated Regulation of the Virulence Genes pcpA, psaBCA, and prtA in Streptococcus
pneumoniae.
Manzoor I; Shafeeq S; Kuipers OP
PLoS One 2015 ;10(11):0-0 pubmedlink 26562538 2015 |
Transcriptional and metabolic effects of glucose on Streptococcus pneumoniae sugar metabolism.
Paixao L; Caldas J; Kloosterman TG; Kuipers OP; Vinga S; Neves AR
Front Microbiol 2015 ;6(0):1041-0 pubmedlink 26500614 2015 |
Microscale insights into pneumococcal antibiotic mutant selection windows.
Sorg RA; Veening JW
Nat Commun 2015 ;6(0):8773-0 pubmedlink 26514094 2015 |
Transcriptional Profile of Bacillus subtilis sigF-Mutant during Vegetative Growth.
Overkamp W; Kuipers OP
PLoS One 2015 ;10(10):0-0 pubmedlink 26506528 2015 |
Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator
CcpA of Bacillus subtilis.
Detert Oude Weme R; Seidel G; Kuipers OP
Front Microbiol 2015 ;6(0):1051-0 pubmedlink 26483775 2015 |
Back to Nature: a revival of natural strain improvement methodologies.
Kuipers OP
Microb Biotechnol 2015 ;8(1):17-8 pubmedlink 25488414 2015 |
The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity.
Zhou L; van Heel AJ; Kuipers OP
Front Microbiol 2015 ;6(0):11-0 pubmedlink 25688235 2015 |
Lactococcus lactis YfiA is necessary and sufficient for ribosome dimerisation.
Puri P; Eckhardt TH; Franken LE; Fusetti F; Stuart MC; Boekema EJ; Kuipers OP; Kok J; Poolman
B
Mol Microbiol 2014 ;91(2):394-407 pubmedlink 24279750 2014 |
Lactic Acid Bacteria: embarking on 30 more years of research.
Kok J; Johansen E; Kleerebezem M; Teusink B
Microb Cell Fact 2014 ;13(0):0-0 pubmedlink 25187380 2014 |
Bacillus subtilis attachment to Aspergillus niger hyphae results in mutually altered metabolism.
Benoit I; van den Esker MH; Patyshakuliyeva A; Mattern DJ; Blei F; Zhou M; Dijksterhuis J; Brakhage AA;
Kuipers OP; de Vries RP; Kovacs AT
Environ Microbiol 2014 ;0(0):0-0 - pubmedlink 25040940 2014 |
Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae.
Yuzenkova Y; Gamba P; Herber M; Attaiech L; Shafeeq S; Kuipers OP; Klumpp S;
Zenkin N; Veening JW
Nucleic Acids Res 2014 ;42(17):10987-99 pubmedlink 25190458 2014 |
Gene Expression Platform for Synthetic Biology in the Human Pathogen Streptococcus pneumoniae.
Sorg RA; Kuipers OP; Veening JW
ACS Synth Biol 2014 ;0(0):0-0 - pubmedlink 24845455 2014 |
LacR is a repressor of lacABCD and LacT an activator of lacTFEG, constituting the lac-gene cluster in Streptococcus
pneumoniae.
Afzal M; Shafeeq S; Kuipers OP
Appl Environ Microbiol 2014 ;0(0):0-0 - pubmedlink 24951784 2014 |
RSV Increases the Virulence of Streptococcus pneumoniae by Binding to PBP1a: a New Paradigm in Respiratory
Infection.
Smith CM; Sandrini S; Datta S; Freestone P; Shafeeq S; Radhakrishnan P; Williams G; Glenn SM; Kuipers
OP; Hirst RA; Easton AJ; Andrew PW; O
Am J Respir Crit Care Med 2014 ;0(0):0-0 - pubmedlink 24941423 2014 |
Control of the Diadenylate Cyclase CdaS in Bacillus subtilis: An Autoinhibitory Domain Limits c-di-AMP Production.
Mehne FM; Schroder-Tittmann K; Eijlander RT; Herzberg C; Hewitt L; Kaever V; Lewis RJ; Kuipers OP;
Tittmann K; Stulke J
J Biol Chem 2014 ;0(0):0-0 - pubmedlink 24939848 2014 |
Bet-hedging during bacterial diauxic shift.
Solopova A; van Gestel J; Weissing FJ; Bachmann H; Teusink B; Kok J; Kuipers OP
Proc Natl Acad Sci U S A 2014 ;0(0):0-0 - pubmedlink 24799698 2014 |
Sensitivity to the two-peptide bacteriocin lactococcin G is dependent on UppP, an enzyme involved in cell-wall
synthesis.
Kjos M; Oppegard C; Diep DB; Nes IF; Veening JW; Nissen-Meyer J; Kristensen T
Mol Microbiol 2014 ;92(6):1177-87 pubmedlink 24779486 2014 |
Density of founder cells affects spatial pattern formation and cooperation in Bacillus subtilis biofilms.
van Gestel J; Weissing FJ; Kuipers OP; Kovacs AT
ISME J 2014 ;0(0):0-0 - pubmedlink 24694715 2014 |
Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin.
Slager J; Kjos M; Attaiech L; Veening JW
Cell 2014 ;157(2):395-406 pubmedlink 24725406 2014 |
Exploiting the peptidoglycan-binding motif, LysM, for medical and industrial applications.
Visweswaran GR; Leenhouts K; van Roosmalen M; Kok J; Buist G
Appl Microbiol Biotechnol 2014 ;0(0):0-0 - pubmedlink 24652063 2014 |
Streptococcus pneumoniae PBP2x mid-cell localization requires the C-terminal PASTA domains and is essential for
cell shape maintenance.
Peters K; Schweizer I; Beilharz K; Stahlmann C; Veening JW; Hakenbeck R; Denapaite D
Mol Microbiol 2014 ;0(0):0-0 - pubmedlink 24655324 2014 |
Interlinked Sister Chromosomes Arise in the Absence of Condensin during Fast Replication in B. subtilis.
Gruber S; Veening JW; Bach J; Blettinger M; Bramkamp M; Errington J
Curr Biol 2014 ;24(3):293-8 pubmedlink 24440399 2014 |
In Bacillus subtilis LutR is part of the global complex regulatory network governing the adaptation to the
transition from exponential growth to stationary phase.
Irigul-Sonmez O; Koroglu TE; Ozturk B; Kovacs AT; Kuipers OP; Yazgan-Karatas A
Microbiology 2014 ;160(0):243-60 pubmedlink 24196425 2014 |
Bacillus subtilis biosensor engineered to assess meat spoilage.
Daszczuk A; Dessalegne Y; Drenth I; Hendriks E; Jo E; van Lente T; Oldebesten A; Parrish J; Poljakova
W; Purwanto AA; van Raaphorst R; Boonstra M; van Heel A; Herber M; van der Meulen
S; Siebring J; Sorg RA; Heinemann M; Kuipers OP; Veening JW
ACS Synth Biol 2014 ;3(12):999-1002 pubmedlink 25524109 2014 |
Bright fluorescent Streptococcus pneumoniae for live cell imaging of host-pathogen interactions.
Kjos M; Aprianto R; Fernandes VE; Andrew PW; van Strijp JA; Nijland R; Veening JW
J Bacteriol 2014 ;0(0):0-0 - pubmedlink 25512311 2014 |
Physiological and cell morphology adaptation of Bacillus subtilis at near-zero specific growth rates: a
transcriptome analysis.
Overkamp W; Ercan O; Herber M; van Maris AJ; Kleerebezem M; Kuipers OP
Environ Microbiol 2014 ;0(0):0-0 - pubmedlink 25367190 2014 |
UlaR activates the expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid.
Afzal M; Shafeeq S; Henriques-Normark B; Kuipers OP
Microbiology 2014 ;0(0):0-0 - pubmedlink 25355938 2014 |
Enterococcus faecalis zinc responsive proteins mediate bacterial defense against zinc overload, lysozyme and
oxidative stress.
Abrantes MC; Kok J; Lopes MD
Microbiology 2014 ;0(0):0-0 - pubmedlink 25312746 2014 |
The HtrA-like protease CD3284 modulates virulence of Clostridium difficile.
Bakker D; Buckley AM; de Jong A; van Winden VJ; Verhoeks JP; Kuipers OP; Douce GR; Kuijper EJ;
Smits WK; Corver J
Infect Immun 2014 ;82(10):4222-32 pubmedlink 25047848 2014 |
Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies.
Claessen D; Rozen DE; Kuipers OP; Sogaard-Andersen L; van Wezel GP
Nat Rev Microbiol 2014 ;12(2):115-124 pubmedlink 24384602 2014 |
The YmdB Phosphodiesterase Is a Global Regulator of Late Adaptive Responses in Bacillus subtilis.
Diethmaier C; Newman JA; Kovacs AT; Kaever V; Herzberg C; Rodrigues C; Boonstra M; Kuipers OP;
Lewis RJ; Stulke J
J Bacteriol 2014 ;196(2):265-75 pubmedlink 24163345 2014 |
Tracking of chromosome dynamics in live Streptococcus pneumoniae reveals that transcription promotes chromosome
segregation.
Kjos M; Veening JW
Mol Microbiol 2014 ;0(0):0-0 - pubmedlink 24417389 2014 |
SporeWeb: an interactive journey through the complete sporulation cycle of Bacillus subtilis.
Eijlander RT; de Jong A; Krawczyk AO; Holsappel S; Kuipers OP
Nucleic Acids Res 2014 ;42(1):0-91 pubmedlink 24170806 2014 |
AcmD, a Homolog of the Major Autolysin AcmA of Lactococcus lactis, Binds to the Cell Wall and Contributes to Cell
Separation and Autolysis.
Visweswaran GR; Steen A; Leenhouts K; Szeliga M; Ruban B; Hesseling-Meinders A; Dijkstra BW;
Kuipers OP; Kok J; Buist G
PLoS One 2013 ;8(8):0-0 pubmedlink 23951292 2013 |
The Presence of Modifiable Residues in the Core Peptide Part of Precursor Nisin Is Not Crucial for Precursor Nisin
Interactions with
Khusainov R; Kuipers OP
PLoS One 2013 ;8(9):0-0 pubmedlink 24040355 2013 |
Repeated triggering of sporulation in Bacillus subtilis selects against a protein that affects the timing of cell
division.
Siebring J; Elema MJ; Drubi Vega F; Kovacs AT; Haccou P; Kuipers OP
ISME J 2013 ;8(1):77-87 pubmedlink 23924781 2013 |
Comparative genomics and transcriptomics analysis of experimentally evolved Escherichia coli MC1000 in complex
environments.
Puentes-Tellez PE; Kovacs AT; Kuipers OP; van Elsas JD
Environ Microbiol 2013 ;16(3):856-870 pubmedlink 24033913 2013 |
NisC Binds the FxLx Motif of the Nisin Leader Peptide.
Abts A; Montalban-Lopez M; Kuipers OP; Smits SH; Schmitt L
Biochemistry 2013 ;52(32):5387-5395 pubmedlink 23869662 2013 |
Benchmarking various GFP variants in Bacillus subtilis, Streptococcus pneumoniae and Lactococcus lactis for live
cell imaging.
Overkamp W; Beilharz K; Detert Oude Weme R; Solopova A; Karsens H; Kovacs
AT; Kok J; Kuipers OP; Veening JW
Appl Environ Microbiol 2013 ;79(20):6481-6490 pubmedlink 23956387 2013 |
How to get (a)round: mechanisms controlling growth and division of coccoid bacteria.
Pinho MG; Kjos M; Veening JW
Nat Rev Microbiol 2013 ;11(9):601-14 pubmedlink 23949602 2013 |
The localization of key Bacillus subtilis penicillin binding proteins during cell growth is determined by substrate
availability.
Lages MC; Beilharz K; Morales Angeles D; Veening JW; Scheffers DJ
Environ Microbiol 2013 ;15(12):3272-3281 pubmedlink 23895585 2013 |
Metabolic and Transcriptional Analysis of Acid Stress in Lactococcus lactis, with a Focus on the Kinetics of Lactic
Acid Pools.
Carvalho AL; Turner DL; Fonseca LL; Solopova A; Catarino T; Kuipers OP; Voit EO; Neves AR; Santos H
PLoS One 2013 ;8(7):0-0 pubmedlink 23844205 2013 |
Pyruvate Oxidase Influences the Sugar Utilization Pattern and Capsule Production in Streptococcus pneumoniae.
Carvalho SM; Farshchi Andisi V; Gradstedt H; Neef J; Kuipers OP; Neves AR; Bijlsma JJ
PLoS One 2013 ;8(7):0-0 pubmedlink 23844180 2013 |
Live cell imaging tool optimization to study gene expression levels and dynamics in single cells of Bacillus
cereus.
Eijlander RT; Kuipers OP
Appl Environ Microbiol 2013 ;79(18):5643-5651 pubmedlink 23851094 2013 |
BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified
peptides.
van Heel AJ; de Jong A; Montalban-Lopez M; Kok J; Kuipers OP
Nucleic Acids Res 2013 ;41(0):0-53 pubmedlink 23677608 2013 |
A single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase renders Streptococcus pneumoniae
dependent on CO and temperature.
Burghout P; Quintero B; Bos L; Beilharz K; Veening JW; de Jonge MI; van der Linden M; van der Ende A;
Hermans PW
Mol Microbiol 2013 ;89(3):494-506 pubmedlink 23750975 2013 |
Identification of distinct nisin leader peptide regions that determine interactions with the modification enzymes
NisB and NisC.
Khusainov R; Moll GN; Kuipers OP
FEBS Open Bio 2013 ;3(0):237-42 pubmedlink 23772400 2013 |
The role of zinc in the interplay between pathogenic streptococci and their hosts.
Shafeeq S; Kuipers OP; Kloosterman TG
Mol Microbiol 2013 ;88(6):1047-57 pubmedlink 23650945 2013 |
Zirex: a novel Zinc-regulated expression system for Lactococcus lactis.
Mu D; Montalban-Lopez M; Masuda Y; Kuipers OP
Appl Environ Microbiol 2013 ;79(14):4503-8 pubmedlink 23666339 2013 |
Balanced transcription of cell division genes in Bacillus subtilis as revealed by single cell analysis.
Trip EN; Veening JW; Stewart EJ; Errington J; Scheffers DJ
Environ Microbiol 2013 ;15(12):3196-3209 pubmedlink 23701187 2013 |
Regulation of arginine acquisition and virulence gene expression in the human pathogen Streptococcus pneumoniae by
transcription regulators ArgR1 and AhrC.
Kloosterman TG; Kuipers OP
J Biol Chem 2013 ;288(15):10950-0 pubmedlink 23585656 2013 |
Environmental and nutritional factors that affect growth and metabolism of the pneumococcal serotype 2 strain d39
and its nonencapsulated derivative strain r6.
Carvalho SM; Kuipers OP; Neves AR
PLoS One 2013 ;8(3):0-0 pubmedlink 23505518 2013 |
Cellobiose-Mediated Gene Expression in Streptococcus pneumoniae: A Repressor Function of the Novel GntR-Type
Regulator BguR.
Shafeeq S; Kuipers OP; Kloosterman TG
PLoS One 2013 ;8(2):0-0 pubmedlink 23469031 2013 |
Designing and Producing Modified, New-to-Nature Peptides with Antimicrobial Activity by Use of a Combination of
Various Lantibiotic Modification Enzymes.
van Heel AJ; Mu D; Montalban-Lopez M; Hendriks D; Kuipers OP
ACS Synth Biol 2013 ;79(14):4503-4508 pubmedlink 23654279 2013 |
EfaR is a major regulator of Enterococcus faecalis manganese transporters and influences processes involved in host
colonization and infection.
Abrantes MC; Kok J; Lopes MD
Infect Immun 2013 ;81(3):935-44 pubmedlink 23297382 2013 |
Functional analysis of the ComK protein of Bacillus coagulans.
Kovacs AT; Eckhardt TH; van Hartskamp M; van Kranenburg R; Kuipers OP
PLoS One 2013 ;8(1):0-0 pubmedlink 23301076 2013 |
The Transcriptional and Gene Regulatory Network of Lactococcus lactis MG1363 during Growth in Milk.
de Jong A; Hansen ME; Kuipers OP; Kilstrup M; Kok J
PLoS One 2013 ;8(1):0-0 pubmedlink 23349698 2013 |
Spo0A regulates chromosome copy number during sporulation by directly binding to the origin of replication in
Bacillus subtilis.
Boonstra M; de Jong IG; Scholefield G; Murray H; Kuipers OP; Veening JW
Mol Microbiol 2013 ;87(4):925-938 pubmedlink 23301687 2013 |
Heterologous Protein Expression by Lactococcus lactis.
Villatoro-Hernandez J; Kuipers OP; Saucedo-Cardenas O; Montes-de-Oca-Luna R
Methods Mol Biol 2012 ;824(0):155-65 pubmedlink 22160898 2012 |
A genetically engineered protein domain binding to bacterial murein, archaeal pseudomurein, and fungal chitin
cell wall material.
Visweswaran GR; Dijkstra BW; Kok J
Appl Microbiol Biotechnol 2012 ;0(0):0-0 - pubmedlink 22262228 2012 |
A Pneumococcal Gene Complex Involved in Resistance to Extracellular Oxidative Stress.
Farshchi Andisi V; Hinojosa CA; de Jong A; Kuipers OP; Orihuela CJ; Bijlsma JJ
Infect Immun 2012 ;80(3):1037-1049 pubmedlink 22215735 2012 |
Culture heterogeneity in zeta potential is linked to Ebp in Enterococcus faecalis.
Tariq M; Bruijs C; Kok J; Krom BP
Appl Environ Microbiol 2012 ;78(7):2282-2288 pubmedlink 22267669 2012 |
Regulation of ykrL (htpX) by Rok and YkrK, a novel type of regulator in Bacillus subtilis.
Marciniak BC; Trip H; Fusetti F; Kuipers OP
J Bacteriol 2012 ;194(11):2837-2845 pubmedlink 22447908 2012 |
Purification and characterization of two phospho-beta-galactosidases, LacG1 and LacG2, from Lactobacillus
gasseri ATCC33323(T).
Honda H; Nagaoka S; Kawai Y; Kemperman R; Kok J; Yamazaki Y; Tateno Y; Kitazawa H; Saito T
J Gen Appl Microbiol 2012 ;58(1):11-7 pubmedlink 22449746 2012 |
High- and low-affinity cre boxes for CcpA bindin in Bacillus Subtilus revealed by genome-wide analysis
Marciniak BC; Pabijaniak M; de Jong A; Duhring R; Seidel G; Hillen W; Kuipers OP
BMC Genomics 2012 ;13(0):401-0 pubmedlink 22900538 2012 |
Single cell analysis of gene expression patterns during carbon starvation in Bacillus subtilis reveals large
phenotypic variation.
de Jong IG; Veening JW; Kuipers OP
Environ Microbiol 2012 ;0(0):0-0 - pubmedlink 23033921 2012 |
CodY, a pleiotropic regulator, influences multicellular behaviour and efficient production of virulence factors
in Bacillus cereus.
Lindback T; Mols M; Basset C; Granum PE; Kuipers OP; Kovacs AT
Environ Microbiol 2012 ;14(8):2233-46 pubmedlink 22540344 2012 |
The putative lactococcal extracytoplasmic function (ECF) anti-sigma factor Llmg2447 determines resistance to the
cell wall-active bacteriocin Lcn972.
Roces C; Perez V; Campelo AB; Blanco D; Kok J; Kuipers OP; Rodriguez A; Martinez B
Antimicrob Agents Chemother 2012 ;0(0):0-0 - pubmedlink 22890757 2012 |
PePPER: a webserver for prediction of prokaryote promoter elements and regulons.
de Jong A; Pietersma H; Cordes M; Kuipers OP; Kok J
BMC Genomics 2012 ;13(1):299-0 pubmedlink 22747501 2012 |
Increasing the success rate of lantibiotic drug discovery by Synthetic Biology.
Montalban-Lopez M; Zhou L; Buivydas A; van Heel AJ; Kuipers OP
Expert Opin Drug Discov 2012 ;0(0):0-0 - pubmedlink 22680308 2012 |
A specific mutation in the promoter region of the silent cel cluster accounts for the appearance of
lactose-utilizing Lactococcus lactis MG1363.
Solopova A; Bachmann H; Teusink B; Kok J; Neves AR; Kuipers OP
Appl Environ Microbiol 2012 ;0(0):0-0 - pubmedlink 22660716 2012 |
Comparative transcriptional analysis of bacillus subtilis cells overproducing either secreted proteins,
lipoproteins or membrane proteins.
Marciniak BC; Trip H; van-der Veek PJ; Kuipers OP
Microb Cell Fact 2012 ;11(1):66-0 pubmedlink 22624725 2012 |
The protective layer of biofilm: a repellent function for a new class of amphiphilic proteins.
Kovacs AT; van Gestel J; Kuipers OP
Mol Microbiol 2012 ;0(0):0-0 - pubmedlink 22607588 2012 |
Control of cell division in Streptococcus pneumoniae by the conserved Ser/Thr protein kinase StkP.
Beilharz K; Novakova L; Fadda D; Branny P; Massidda O; Veening JW
Proc Natl Acad Sci U S A 2012 ;0(0):0-0 - pubmedlink 22431591 2012 |
Perspectives on the contribution of lactic acid bacteria to cheese flavor development.
Steele J; Broadbent J; Kok J
Curr Opin Biotechnol 2012 ;0(0):0-0 - pubmedlink 23279928 2012 |
Transcriptional regulation of fatty acid biosynthesis in Lactococcus lactis.
Eckhardt TH; Skotnicka D; Kok J; Kuipers OP
J Bacteriol 2012 ;0(0):0-0 - pubmedlink 23275247 2012 |
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations
for a universal nomenclature.
Arnison PG; Bibb MJ; Bierbaum G; Bowers AA; Bugni TS; Bulaj G; Camarero JA; Campopiano DJ; Challis GL; Clardy J;
Cotter PD; Craik DJ; Dawson M; Dittmann E; Donadio S; Dorrestein PC; Entian KD; Fischbach MA; Garavelli JS;
Goransson U; Gruber CW; Haft DH; Hemscheidt TK; Hertweck C; Hill C; Horswill AR; Jaspars M; Kelly WL; Klinman JP;
Kuipers OP; Link AJ; Liu W; Marahiel MA; Mitchell DA; Moll GN; Moore BS; Muller R; Nair SK; Nes IF;
Norris GE; Olivera BM; Onaka H; Patchett ML; Piel J; Reaney MJ; Rebuffat S; Ross RP; Sahl HG; Schmidt EW; Selsted
ME; Severinov K; Shen B; Sivonen K; Smith L; Stein T; Sussmuth RD; Tagg JR; Tang GL; Truman AW; Vederas JC; Walsh
CT; Walton JD; Wenzel SC; Willey JM; van der Donk WA
Nat Prod Rep 2012 ;30(1):108-60 pubmedlink 23165928 2012 |
Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features
of a PadR Subfamily.
Fibriansah G; Kovacs AT; Pool TJ; Boonstra M; Kuipers OP; Thunnissen AM
PLoS One 2012 ;7(11):0-0 pubmedlink 23189126 2012 |
The DEAD-box RNA helicases in Bacillus subtilis have multiple functions and act independent from each other.
Lehnik-Habrink M; Rempeters L; Kovacs AT; Wrede C; Baierlein C; Krebber H; Kuipers OP; Stulke J
J Bacteriol 2012 ;0(0):0-0 - pubmedlink 23175651 2012 |
Characterization of the ROK-family transcriptional regulator RokA of Streptococcus pneumoniae D39.
Shafeeq S; Kloosterman TG; Rajendran V; Kuipers OP
Microbiology 2012 ;0(0):0-0 - pubmedlink 23082033 2012 |
When the Leader Gets Loose: In Vivo Biosynthesis of a Leaderless Prenisin Is Stimulated by a trans-Acting Leader
Peptide.
Khusainov R; Kuipers OP
Chembiochem 2012 ;0(0):0-0 - pubmedlink 23070977 2012 |
Understanding microbial behavior within and outside the host to improve food functionality and safety.
Abee T; Kuipers OP
Curr Opin Biotechnol 2011 ;22(0):133-135 pubmedlink 21334191 2011 |
Rok regulates yuaB expression during architecturally complex colony development of Bacillus subtilis 168.
Kovacs AT; Kuipers OP
J Bacteriol 2011 ;193(0):998-1002 pubmedlink 21097620 2011 |
Bacterial spores in food: how phenotypic variability complicates prediction of spore properties and bacterial
behavior.
Eijlander RT; Abee T; Kuipers OP
Curr Opin Biotechnol 2011 ;22(0):180-186 pubmedlink 21134736 2011 |
Bet hedging or not? A guide to proper classification of microbial survival strategies.
de Jong IG; Haccou P; Kuipers OP
Bioessays 2011 ;33(3):215-223 pubmedlink 21254151 2011 |
Gene cluster for biosynthesis of thermophilin 1
Kabuki T; Kawai Y; Uenishi H; Seto Y; Kok J; Nakajima H; Saito T
J Appl Microbiol 2011 ;110(3):641-649 pubmedlink 21182576 2011 |
Targeting diseases with genetically engineered Lactococcus lactis and its course towards medical translation.
Villatoro-Hernandez J; Montes-de-Oca-Luna R; Kuipers OP
Expert Opin Biol Ther 2011 ;11(3):261-267 pubmedlink 21204744 2011 |
DnaA and ORC: more than DNA replication initiators.
Scholefield G; Veening JW; Murray H
Trends Cell Biol 2011 ;21(3):188-194 pubmedlink 21123069 2011 |
Biofilm formation and dispersal in Gram-positive bacteria.
Abee T; Kovacs AT; Kuipers OP; van der Veen S
Curr Opin Biotechnol 2011 ;22(0):172-179 pubmedlink 21109420 2011 |
Deletion of a cation transporter promotes lysis in Streptococcus pneumoniae.
Neef J; Farshchi Andisi V; Kim KS; Kuipers OP; Bijlsma JJ
Infect Immun 2011 ;79(0):2314-2323 pubmedlink 21422174 2011 |
Data resources and mining tools for reconstructing gene regulatory networks in Lactococcus lactis
de Jong A; Kok J; Kuipers OP
Japanese Journal of Lactic Acid Bacteria 2011 ;22(1):1-14 2011 |
Evaluating the feasibility of lantibiotics as an alternative therapy against bacterial infections in humans.
van Heel AJ; Montalban-Lopez M; Kuipers OP
Expert Opin Drug Metab Toxicol 2011 ;6(0):675-680 pubmedlink 21521092 2011 |
Genome Exploitation and Bioinformatics Tools
de Jong A; van Heel AJ; Kuipers OP
Prokaryotic Antimicrobial Peptides: From Genes to Applications 2011 ;0(0):0-0 - 2011 |
The regulon of the N-Acetylglucosamine utilization regulator (NagR) in Bacillus subtilis.
Bertram R; Rigali S; Wood N; Lulko AT; Kuipers OP; Titgemeyer F
J Bacteriol 2011 ;198(14):609-618 pubmedlink 21602348 2011 |
Distinct Roles of ComK1 and ComK2 in Gene Regulation in Bacillus cereus.
Mironczuk AM; Manu A; Kuipers OP; Kovacs AT
PLoS One 2011 ;6(7):0-0 pubmedlink 21747963 2011 |
A Minimum of Three Motifs Is Essential for Optimal Binding of Pseudomurein Cell Wall-Binding Domain of
Methanothermobacter thermautotrophicus.
Visweswaran GR; Dijkstra BW; Kok J
PLoS One 2011 ;6(6):0-0 pubmedlink 21738718 2011 |
Efficient Overproduction of Membrane Proteins in Lactococcus lactis Requires the Cell Envelope Stress
Sensor/Regulator Couple CesSR.
Pinto JP; Kuipers OP; Marreddy RK; Poolman B; Kok J
PLoS One 2011 ;6(7):0-0 pubmedlink 21818275 2011 |
pSEUDO, a genetic integration standard for Lactococcus lactis.
Pinto JP; Zeyniyev A; Karsens H; Trip H; Lolkema JS; Kuipers OP; Kok J
Appl Environ Microbiol 2011 ;77(18):6687-6690 pubmedlink 21764949 2011 |
The Lcn972-bacteriocin plasmid pBL1 impairs cellobiose metabolism in Lactococcus lactis.
Campelo AB; Gaspar P; Roces C; Rodriguez A; Kok J; Kuipers OP; Neves AR; Martinez B
Appl Environ Microbiol 2011 ;77(21):7576-7585 pubmedlink 21890668 2011 |
The Response of Lactococcus lactis to Membrane Protein Production.
Marreddy RK; Pinto JP; Wolters JC; Geertsma ER; Fusetti F; Permentier HP; Kuipers OP; Kok J;
Poolman B
PLoS One 2011 ;6(8):0-0 pubmedlink 21904605 2011 |
Determining sites of interaction between prenisin and its modification enzymes NisB and NisC.
Khusainov R; Heils R; Lubelski J; Moll GN; Kuipers OP
Mol Microbiol 2011 ;82(3):706-18 pubmedlink 22011325 2011 |
Transcriptional responses of Bacillus cereus towards challenges with the polysaccharide chitosan.
Mellegard H; Kovacs AT; Lindback T; Christensen BE; Kuipers OP; Granum PE
PLoS One 2011 ;6(9):0-0 pubmedlink 21931677 2011 |
Responses of Lactic Acid Bacteria to Cell Envelope Stresses (chapter 8)
Pinto J.P.C., Kuipers O.P., Kok J.
Book: Stress Responses of Lactic Bacteria ISBN 978-0-387-92770-1 2011 ;0(0):145-161 - 2011 |
Future Challenges in Lactic Acid Bacteria Stress Physiology Research (chapter 21)
Papadimitriou K, Kok, J.
Book: Sress Responses of lactic Acid Bacteria ISBN 978-0-387-91771-8 2011 ;0(0):507-518 - 2011 |
Bacillus cereus responses to acid stress.
Mols M; Abee T
Environ Microbiol 2011 ;13(11):2835-43 pubmedlink 21554514 2011 |
Regulation of Arginine Acquisition and Virulence Gene Expression in the Human Pathogen Streptococcus pneumoniae
by Transcription Regulators ArgR1 and AhrC.
Kloosterman TG; Kuipers OP
J Biol Chem 2011 ;286(52):44594-605 pubmedlink 22084243 2011 |
Large-Scale Screening of a Targeted Enterococcus faecalis Mutant Library Identifies Envelope Fitness Factors.
Rigottier-Gois L; Alberti A; Houel A; Taly JF; Palcy P; Manson J; Pinto D; Matos RC; Carrilero L; Montero N;
Tariq M; Karsens H; Repp C; Kropec A; Budin-Verneuil A; Benachour A; Sauvageot N; Bizzini A; Gilmore
MS; Bessieres P; Kok J; Huebner J; Lopes F; Gonzalez-Zorn B; Hartke A; Serror P
PLoS One 2011 ;6(12):0-0 pubmedlink 22194979 2011 |
A novel screening system for secretion of heterologous proteins in Bacillus subtilis.
Trip H; van der Veek PJ; Renniers TC; Meima R; Sagt CM; Mohrmann L; Kuipers OP
Microb Biotechnol 2011 ;0(0):0-0 - pubmedlink 21624103 2011 |
The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae.
Shafeeq S; Yesilkaya H; Kloosterman TG; Narayanan G; Andrew PW; Kuipers OP; Morrissey JA
Mol Microbiol 2011 ;0(0):0-0 - pubmedlink 21736642 2011 |
Time-resolved transcriptomics and bioinformatic analyses reveal intrinsic stress responses during batch culture
of Bacillus subtilis.
Blom EJ; Ridder AN; Lulko AT; Roerdink JB; Kuipers OP
PLoS One 2011 ;6(11):0-0 pubmedlink 22087258 2011 |
The proceedings of the Tenth Symposium on Lactic Acid Bacteria.
Hill C; Kleerebezem M; Kok J
Microb Cell Fact 2011 ;10(0):0-0 pubmedlink 21995427 2011 |
Potential antibiotic and anti-infective effects of rhodomyrtone from Rhodomyrtus tomentosa (Aiton) Hassk. on
Streptococcus pyogenes as revealed by proteomics.
Limsuwan S; Hesseling-Meinders A; Voravuthikunchai SP; van Dijl JM; Kayser O
Phytomedicine 2011 ;0(0):0-0 - pubmedlink 21439802 2011 |
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae.
Minnen A; Attaiech L; Thon M; Gruber S; Veening JW
Mol Microbiol 2011 ;0(0):0-0 - pubmedlink 21651626 2011 |
Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy.
de Jong IG; Beilharz K; Kuipers OP; Veening JW
J Vis Exp 2011 ;0(53):0-0 - pubmedlink 21841760 2011 |
Transcriptional response of Streptococcus pneumoniae to Zn(2+) limitation and the repressor/activator function
of AdcR.
Shafeeq S; Kloosterman TG; Kuipers OP
Metallomics 2011 ;3(6):609-618 pubmedlink 21603707 2011 |
From meadows to milk to mucosa - adaptation of Streptococcus and Lactococcus species to their nutritional
environment
Price CE; Zeyniyev A; Kuipers OP; Kok J
FEMS Microbiol Rev 2011 ;0(0):0-0 - pubmedlink 22212109 2011 |
Murein and pseudomurein cell wall binding domains of bacteria and archaea-a comparative view.
Visweswaran GR; Dijkstra BW; Kok J
Appl Microbiol Biotechnol 2011 ;0(0):0-0 - pubmedlink 22012341 2011 |
Impact of Manganese, Copper and Zinc Ions on the Transcriptome of the Nosocomial Pathogen Enterococcus faecalis
V583.
Coelho Abrantes M; Lopes Mde F; Kok J
PLoS One 2011 ;6(10):0-0 pubmedlink 22053193 2011 |
CcpA ensures optimal metabolic fitness of Streptococcus pneumoniae.
Carvalho SM; Kloosterman TG; Kuipers OP; Neves AR
PLoS One 2011 ;6(10):0-0 pubmedlink 22039538 2011 |
CelR-mediated activation of the cellobiose-uptake gene cluster in Streptococcus pneumoniae.
Shafeeq S; Kloosterman TG; Kuipers OP
Microbiology 2011 ;0(0):0-0 - pubmedlink 21778207 2011 |
Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic
machinery and leader sequence.
Majchrzykiewicz JA; Lubelski J; Moll GN; Kuipers A; Bijlsma JJ; Kuipers OP; Rink
R
Antimicrob Agents Chemother 2010 ;54(0):1498-505 pubmedlink 20100873 2010 |
Adaptation of Hansenula polymorpha to methanol: a transcriptome analysis.
van Zutphen T; Baerends RJ; Susanna KA; de Jong A; Kuipers OP; Veenhuis M; van der Klei
IJ
BMC Genomics 2010 ;11(1):1-0 pubmedlink 20044946 2010 |
Generic and specific adaptive responses of Streptococcus pneumoniae to challenge with three distinct
antimicrobial peptides, bacitracin, LL-37, and nisin.
Majchrzykiewicz JA; Kuipers OP; Bijlsma JJ
Antimicrob Agents Chemother 2010 ;54(1):440-51 pubmedlink 19917758 2010 |
Transformation of environmental bacillus subtilis isolates by transiently inducing genetic competence.
Nijland R; Burgess JG; Errington J; Veening JW
PLoS One 2010 ;5(3):0-0 pubmedlink 20300532 2010 |
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis.
Chillappagari S; Seubert A; Trip H; Kuipers OP; Marahiel MA; Miethke M
J Bacteriol 2010 ;192(10):2512-2524 pubmedlink 20233928 2010 |
Gene position within a long transcript as a determinant for stochastic switching in bacteria.
Veening JW; Kuipers OP
Mol Microbiol 2010 ;76(2):269-272 pubmedlink 20233302 2010 |
Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation.
de Jong IG; Veening JW; Kuipers OP
J Bacteriol 2010 ;192(8):2053-2067 pubmedlink 20154131 2010 |
sigma54-Mediated control of the mannose phosphotransferase sytem in Lactobacillus plantarum impacts on
carbohydrate metabolism.
Stevens MJ; Molenaar D; de Jong A; De Vos WM; Kleerebezem M
Microbiology 2010 ;156(0):695-707 pubmedlink 19942662 2010 |
Introducing a new host for biotechnology: Genetic tool development for the thermotolerant Bacillus coagulans.
Kovacs AT; van Hartskamp M; Kuipers OP; van Kranenburg R
Appl Environ Microbiol 2010 ;11(0):1911-1922 pubmedlink 20400555 2010 |
Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis.
Marreddy RK; Geertsma ER; Permentier HP; Pinto JP; Kok J; Poolman B
PLoS One 2010 ;5(4):0-0 pubmedlink 20436673 2010 |
BAGEL2: mining for bacteriocins in genomic data.
de Jong A; van Heel AJ; Kok J; Kuipers OP
Nucleic Acids Res 2010 ;0(0):1-5 - pubmedlink 20462861 2010 |
Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus
subtilis.
Hyyrylainen HL; Marciniak BC; Dahncke K; Pietiainen M; Courtin P; Vitikainen M; Seppala R; Otto A; Becher D;
Chapot-Chartier MP; Kuipers OP; Kontinen VP
Mol Microbiol 2010 ;77(1):108-127 pubmedlink 20487272 2010 |
Genome sequences of Lactococcus lactis MG1363 (revised) and NZ9000 and comparative physiological studies.
Linares DM; Kok J; Poolman B
J Bacteriol 2010 ;192(21):5806-5812 pubmedlink 20639323 2010 |
How mathematical modelling elucidates signalling in B. subtilis.
Liebal UW; Millat T; de Jong IG; Kuipers OP; Volker U; Wolkenhauer O
2010 ;77(5):1083-1095 pubmedlink 20624218 2010 |
Towards enhanced galactose utilization by Lactococcus lactis.
Neves AR; Pool WA; Solopova A; Kok J; Santos H; Kuipers OP
Appl Environ Microbiol 2010 ;76(21):7048-7060 pubmedlink 20817811 2010 |
SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks.
Westenberg MA; Roerdink JB; Kuipers OP; van Hijum SA
Bioinformatics 2010 ;26(22):2922-2923 pubmedlink 20861033 2010 |
Two Major Archaeal Pseudomurein Endoisopeptidases: PeiW and PeiP.
Visweswaran GR; Dijkstra BW; Kok J
Archaea 2010 ;2010(0):480492-0 pubmedlink 21113291 2010 |
Genetic tool development for a new host for biotechnology, the thermotolerant bacterium Bacillus coagulans.
Kovacs AT; van Hartskamp M; Kuipers OP; van Kranenburg R
Appl Environ Microbiol 2010 ;76(12):4085-8 pubmedlink 20400555 2010 |
Relaxed specificity of the Bacillus subtilis TatAdCd translocase in Tat-dependent protein secretion.
Eijlander RT; Jongbloed JD; Kuipers OP
J Bacteriol 2009 ;19(1):196-202 pubmedlink 18978042 2009 |
MINOMICS: visualizing prokaryote transcriptomics and proteomics data in a genomic context.
Brouwer RW; Hijum SA; Kuipers OP
Bioinformatics 2009 ;25(1):139-140 pubmedlink 19008250 2009 |
The twin-arginine translocation (Tat) systems from Bacillus subtilis display a conserved mode of complex
organization and similar substrate recognition requirements.
Barnett JP; van der Ploeg R; Eijlander RT; Nenninger A; Mendel S; Rozeboom R; Kuipers OP; van Dijl
JM; Robinson C
FEBS J 2009 ;276(1):232-243 pubmedlink 19049517 2009 |
Characterization of the individual glucose uptake systems of Lactococcus lactis: mannose-PTS, cellobiose-PTS
and the novel GlcU permease.
Castro R; Neves AR; Fonseca LL; Pool WA; Kok J; Kuipers OP; Santos H
Mol Microbiol 2009 ;71(3):795-806 pubmedlink 19054326 2009 |
DNA Sequencing and Homologous Expression of a Small Peptide Conferring Immunity to Gassericin A, a Circular
Bacteriocin Produced by Lactobacillus gasseri LA39.
Kawai Y; Kusnadi J; Kemperman R; Kok J; Ito Y; Endo M; Arakawa K; Uchida H; Nishimura J; Kitazawa H; Saito T
Appl Environ Microbiol 2009 ;75(0):1324-1330 pubmedlink 19114506 2009 |
MOTIFATOR: detection and characterization of regulatory motifs using prokaryote transcriptome data.
Blom EJ; Roerdink JB; Kuipers OP; van Hijum SA
Bioinformatics 2009 ;25(4):550-551 pubmedlink 19168910 2009 |
Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.
Chillappagari S; Miethke M; Trip H; Kuipers OP; Marahiel MA
J Bacteriol 2009 ;191(7):2362-2370 pubmedlink 19168619 2009 |
Subcellular localisation of TatAd of Bacillus subtilis depends on the presence of TatCd or TatCy.
Ridder AN; de Jong EJ; Jongbloed JD; Kuipers OP
J Bacteriol 2009 ;191(13):4410-4418 pubmedlink 19395490 2009 |
Effects of altered TatC proteins on protein secretion efficiency via the twin-arginine translocation pathway of
Bacillus subtilis.
Eijlander RT; Kolbusz MA; Berendsen EM; Kuipers OP
Microbiology 2009 ;155(0):1776-1785 pubmedlink 19383693 2009 |
Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.
Hendriksen WT; Bootsma HJ; van Diepen A; Estevao S; Kuipers OP; de Groot R; Hermans PW
Microbiology 2009 ;155(0):1569-79 pubmedlink 19372167 2009 |
Mechanisms and evolution of control logic in prokaryotic transcriptional regulation.
van Hijum SA; Medema MH; Kuipers OP
Microbiol Mol Biol Rev 2009 ;73(3):481-509 pubmedlink 19721087 2009 |
Ubiquitous late competence genes in Bacillus species indicate the presence of functional DNA uptake machineries.
Kovacs AT; Smits WK; Mironczuk AM; Kuipers OP
Environ Microbiol 2009 ;11(8):1911-22 pubmedlink 19453701 2009 |
Cellular localization of choline-utilization proteins in Streptococcus pneumoniae using novel fluorescent
reporter systems.
Eberhardt A; Wu LJ; Errington J; Vollmer W; Veening JW
Mol Microbiol 2009 ;74(2):395-408 pubmedlink 19737355 2009 |
Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin.
Lubelski J; Khusainov R; Kuipers OP
J Biol Chem 2009 ;284(38):25962-72 pubmedlink 19620240 2009 |
Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48.
Grande Burgos MJ; Kovacs AT; Mironczuk AM; Abriouel H; Galvez A; Kuipers OP
BMC Microbiol 2009 ;0(0):0-0 - pubmedlink 19863785 2009 |
Transcriptome and proteome analysis of ovaries of arrhenotokous and thelytokous Venturia canescens.
Mateo Leach I; Hesseling A; Huibers WH; Witsenboer H; Beukeboom LW; van de Zande L
Insect Mol Biol 2009 ;18(4):477-82 pubmedlink 19453764 2009 |
Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin.
Lubelski J; Rink R; Khusainov R; Moll GN; Kuipers OP
Cell Mol Life Sci 2008 ;65(3):455-476 pubmedlink 17965835 2008 |
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization.
Hendriksen WT; Bootsma HJ; Estevao S; Hoogenboezem T; de Jong A; de Groot R; Kuipers OP; Hermans PW
J Bacteriol 2008 ;190(2):590-601 pubmedlink 18024519 2008 |
The Escherichia coli TatABC system and a Bacillus subtilis TatAC-type system recognise three distinct targeting
determinants in twin-arginine signal peptides.
Mendel S; McCarthy A; Barnett JP; Eijlander RT; Nenninger A; Kuipers OP; Robinson C
J Mol Biol 2008 ;375(3):661-72 pubmedlink 18036542 2008 |
A minimal Tat system from a gram-positive organism: a bifunctional TatA subunit participates in discrete TatAC
and TatA complexes.
Barnett JP; Eijlander RT; Kuipers OP; Robinson C
J Biol Chem 2008 ;283(5):2534-2542 pubmedlink 18029357 2008 |
A facile reporter system for the experimental identification of twin-arginine translocation (Tat) signal
peptides from all kingdoms of life.
Widdick DA; Eijlander RT; van Dijl JM; Kuipers OP; Palmer T
J Mol Biol 2008 ;375(3):595-603 pubmedlink 18054046 2008 |
Site-specific contributions of glutamine-dependent regulator GlnR and GlnR-regulated genes to virulence of
Streptococcus pneumoniae.
Hendriksen WT; Kloosterman TG; Bootsma HJ; Estevao S; de Groot R; Kuipers OP; Hermans PW
Infect Immun 2008 ;76(3):1230-8 pubmedlink 18174343 2008 |
LmrR is a transcriptional repressor of expression of the multidrug ABC transporter LmrCD in Lactococcus lactis.
Agustiandari H; Lubelski J; van den Berg van Saparoea HB; Kuipers OP; Driessen AJ
J Bacteriol 2008 ;190(2):759-63 pubmedlink 17993533 2008 |
Bet-hedging and epigenetic inheritance in bacterial cell development.
Veening JW; Stewart EJ; Berngruber TW; Taddei F; Kuipers OP; Hamoen LW
Proc Natl Acad Sci U S A 2008 ;105(11):4393-4398 pubmedlink 18326026 2008 |
LysM, a widely distributed protein motif for binding to (peptido)glycans.
Buist G; Steen A; Kok J; Kuipers OP
Mol Microbiol 2008 ;68(4):838-47 pubmedlink 18430080 2008 |
The relative value of operon predictions.
Brouwer RW; Kuipers OP; Hijum SA
Brief Bioinform 2008 ;9(5):367-375 pubmedlink 18420711 2008 |
Assessment of CcpA-mediated catabolite control of gene expression in Bacillus cereus ATCC 14579.
van der Voort M; Kuipers OP; Buist G; de Vos WM; Abee T
BMC Microbiol 2008 ;8(1):62-0 pubmedlink 18416820 2008 |
Transient heterogeneity in extracellular protease production by Bacillus subtilis.
Veening JW; Igoshin OA; Eijlander RT; Nijland R; Hamoen LW; Kuipers OP
Mol Syst Biol 2008 ;4(0):184-0 pubmedlink 18414485 2008 |
Improvement of Lactobacillus plantarum Aerobic Growth, Directed by Comprehensive Transcriptome Analysis.
Stevens MJ; Wiersma A; De Vos WM; Kuipers OP; Smid EJ; Molenaar D; Kleerebezem M
Appl Environ Microbiol 2008 ;74(15):4776-4778 pubmedlink 18539801 2008 |
Opposite effects of Mn2+ and Zn2+ on the PsaR-mediated expression of the virulence genes pcpA, prtA and psaBCA
of Streptococcus pneumoniae.
Kloosterman T; Witwicki RM; van der Kooi-Pol MM; Bijlsma JJ; Kuipers OP
J Bacteriol 2008 ;190(15):5382-5393 pubmedlink 18515418 2008 |
The influence of shifting positions of Ser, Thr and Cys residues in prenisin on the efficiency of modification
reactions and on the antimicrobial activity of the modified propeptides.
Lubelski J; Overkamp W; Kluskens LD; Moll GN; Kuipers OP
Appl Environ Microbiol 2008 ;74(15):4680-4685 pubmedlink 18539792 2008 |
Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the
autolysin AcmA.
Steen A; Buist G; Kramer NE; Jalving R; Benus GF; Venema G; Kuipers OP; Kok J
Appl Environ Microbiol 2008 ;74(15):4671-4679 pubmedlink 18539791 2008 |
Transcriptome analysis of the ArgR and AhrC regulons in Lactococcus lactis.
Larsen R; van Hijum SA; Martinussen J; Kuipers OP; Kok J
Appl Environ Microbiol 2008 ;74(15):4768-4771 pubmedlink 18539789 2008 |
Bistability, Epigenetics, and Bet-Hedging in Bacteria.
Veening JW; Smits WK; Kuipers OP
Annu Rev Microbiol 2008 ;62(0):193-210 pubmedlink 18537474 2008 |
Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin
resistance mechanism of Lactococcus lactis.
Kramer NE; Hasper HE; van den Bogaard PT; Morath S; de Kruijff B; Hartung T; Smid EJ; Breukink E; Kok
J; Kuipers OP
Microbiology 2008 ;154(0):1755-62 pubmedlink 18524930 2008 |
The ABC-type MDR transporter LmrCD is responsible for an extrusion based mechanism of bile acid resistance in
Lactococcus lactis.
Zaidi AH; Bakkes PJ; Lubelski J; Agustiandari H; Kuipers OP; Driessen AJ
J Bacteriol 2008 ;190(22):7357-66 pubmedlink 18790870 2008 |
Prosecutor: parameter-free inference of gene function for prokaryotes using DNA microarray data, genomic context
and multiple gene annotation sources.
Blom EJ; Breitling R; Hofstede KJ; Roerdink JB; van Hijum SA; Kuipers OP
BMC Genomics 2008 ;9(1):495-0 pubmedlink 18939968 2008 |
Supervised Lowess normalization of comparative genome hybridization data--application to lactococcal strain
comparisons.
van Hijum SA; Baerends RJ; Zomer AL; Karsens HA; Martin-Requena V; Trelles O; Kok
J; Kuipers OP
BMC Bioinformatics 2008 ;9(0):93-93 pubmedlink 18267014 2008 |
Visualizing genome expression and regulatory network dynamics in genomic and metabolic context
Westenberg MA; van Hijum SAFT; Kuipers OP; Roerdink JBTM
Computer Graphics Forum 2008 ;27(3):887-894 2008 |
DISCLOSE : DISsection of CLusters Obtained by SEries of transcriptome data using functional annotations and
putative transcription factor binding sites.
Blom EJ; van Hijum SA; Hofstede KJ; Silvis R; Roerdink JB; Kuipers OP
BMC Bioinformatics 2008 ;9(1):535-0 pubmedlink 19087282 2008 |
Optimization of protein secretion by Bacillus subtilis.
Nijland R; Kuipers OP
Recent Pat Biotechnol 2008 ;2(2):79-87 pubmedlink 19075856 2008 |
Comparative analysis of cervical cancer patients (late stage survival) before and after medical treatment. In:
Biomarker Discovery for Cervical Cancer. Methods and Approaches.
Govorukhina, N.I;, Hesseling, A.;, Horvatovich, P.; de Vries, M.; Suits, A.; Bisschoff, R.
2008 ;0(0):153-178 - 2008 |
Induction of natural competence in Bacillus cereus ATCC14579
Mironczuk AM; Kovacs AT; Kuipers OP
Microbial Biotechnology 2008 ;1(3):226-235 2008 |
9th International Symposium on Lactic Acid Bacteria.
Kuipers OP; Poolman B; Hugenholtz J
Appl Environ Microbiol 2008 ;74(15):4589-0 pubmedlink 18586976 2008 |
Changing a single amino acid in Clostridium perfringens {beta}-toxin affects efficiency of heterologous
secretion by Bacillus subtilis.
Nijland R; Heerlien R; Hamoen LW; Kuipers OP
Appl Environ Microbiol 2007 ;73(5):1586-1593 pubmedlink 17209068 2007 |
Heterologous production and secretion of Clostridium perfringens beta-toxoid in closely related Gram-positive
hosts.
Nijland R; Lindner C; van Hartskamp M; Hamoen LW; Kuipers OP
J Biotechnol 2007 ;127(3):361-72 pubmedlink 16959352 2007 |
Transcriptome Analysis of Temporal Regulation of Carbon Metabolism by CcpA in Bacillus subtilis Reveals
Additional Target Genes.
Lulko AT; Buist G; Kok J; Kuipers OP
J Mol Microbiol Biotechnol 2007 ;12(1):82-95 pubmedlink 17183215 2007 |
Time-resolved determination of the CcpA regulon of Lactococcus lactis spp. cremoris MG1363.
Zomer AL; Buist G; Larsen R; Kok J; Kuipers OP
J Bacteriol 2007 ;189(4):1366-1381 pubmedlink 17028270 2007 |
Regulation of gene expression in Streptococcus pneumoniae by response regulator 09 is Strain-Dependent.
Hendriksen WT; Silva N; Bootsma HJ; Blue CE; Paterson GK; Kerr AR; de Jong A; Kuipers OP; Hermans PW;
Mitchell TJ
J Bacteriol 2007 ;189(4):1382-1389 pubmedlink 17085554 2007 |
FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of
prokaryotes.
Blom EJ; Bosman DW; van Hijum SA; Breitling R; Tijsma L; Silvis R; Roerdink JB; Kuipers
OP
Bioinformatics 2007 ;23(9):1161-1163 pubmedlink 17237043 2007 |
Production of dehydroamino acid-containing peptides by Lactococcus lactis.
Rink R; Wierenga J; Kuipers A; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN
Appl Environ Microbiol 2007 ;73(6):1792-1796 pubmedlink 17261515 2007 |
Development of Genomic Array Footprinting for the Identification of Conditionally Essential Genes in
Streptococcus pneumoniae.
Bijlsma JJ; Burghout P; Kloosterman TG; Bootsma HJ; de Jong A; Hermans PW; Kuipers OP
Appl Environ Microbiol 2007 ;73(5):1514-1524 pubmedlink 17261526 2007 |
A de-repression system based on the Bacillus subtilis sporulation pathway offers dynamic control of
heterologous gene expression.
Nijland R; Veening JW; Kuipers OP
Appl Environ Microbiol 2007 ;73(7):2390-2393 pubmedlink 17293533 2007 |
The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363.
Wegmann U; O'Connell-Motherway M; Zomer A; Buist G; Shearman C; Canchaya C; Ventura M; Goesmann A;
Gasson MJ; Kuipers OP; Van Sinderen D; Kok J
J Bacteriol 2007 ;189(8):3256-3270 pubmedlink 17307855 2007 |
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward
Podosphaera fusca.
Romero D; de Vicente A; Rakotoaly RH; Dufour SE; Veening JW; Arrebola E; Cazorla FM; Kuipers
OP; Paquot M; Perez-Garcia A
Mol Plant Microbe Interact 2007 ;20(4):430-40 pubmedlink 17427813 2007 |
Production and Secretion Stress Caused by Overexpression of Heterologous {alpha}-Amylase Leads to Inhibition of
Sporulation and a Prolonged Motile Phase in Bacillus subtilis.
Lulko AT; Veening JW; Buist G; Smits WK; Blom EJ; Beekman AC; Bron S;
Kuipers OP
Appl Environ Microbiol 2007 ;73(16):5354-62 pubmedlink 17586671 2007 |
Novel methods for genetic transformation of natural Bacillus subtilis isolates used to study regulation of the
mycosubtilin and surfactin synthetases.
Duitman EH; Wyczawski D; Boven LG; Venema G; Kuipers OP; Hamoen LW
Appl Environ Microbiol 2007 ;73(11):3490-3496 pubmedlink 17416694 2007 |
A single, specific thymine mutation in the ComK-binding site severely decreases binding and transcription
activation by the competence transcription factor ComK of Bacillus subtilis.
Susanna KA; Mironczuk AM; Smits WK; Hamoen LW; Kuipers OP
J Bacteriol 2007 ;189(13):4718-4728 pubmedlink 17468244 2007 |
Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the lactococcal two-component system
CesSR.
Martinez B; Zomer AL; Rodriguez A; Kok J; Kuipers OP
Mol Microbiol 2007 ;64(2):473-86 pubmedlink 17493129 2007 |
Antirepression as a second mechanism of transcriptional activation by a minor groove binding protein.
Smits WK; Hoa TT; Hamoen LW; Kuipers OP; Dubnau D
Mol Microbiol 2007 ;64(2):368-81 pubmedlink 17493123 2007 |
SPxB regulates o-acetylation dependent resistance of lactococcus lactis peptidoglycan to hydrolysis.
Veiga P; Bulbarela-Sampieri C; Furlan S; Maisons A; Chapot-Chartier MP; Erkelenz M; Mervelet P; Noirot P;
Frees D; Kuipers O; Kok J; Gruss A; Buist G; Kulakauskas S
J Biol Chem 2007 ;282(27):19342-19354 pubmedlink 17485463 2007 |
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by
C-terminal truncation.
Rink R; Wierenga J; Kuipers A; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN
Appl Environ Microbiol 2007 ;73(18):5809-5816 pubmedlink 17660303 2007 |
MOVE: A Multi-level Ontology-based Visualization and Exploration framework for genomic networks.
Bosman DW; Blom EJ; Ogao PJ; Kuipers OP; Roerdink JB
In Silico Biol 2007 ;7(1):35-59 pubmedlink 17688427 2007 |
The novel transcriptional regulator SczA mediates protection against Zn(2+) stress by activation of the
Zn(2+)-resistance gene czcD in Streptococcus pneumoniae.
Kloosterman TG; van der Kooi-Pol MM; Bijlsma JJ; Kuipers OP
Mol Microbiol 2007 ;65(4):1049-63 pubmedlink 17640279 2007 |
Search for genes essential for pneumococcal transformation: the RadA DNA repair protein plays a role in genomic
recombination of donor DNA.
Burghout P; Bootsma HJ; Kloosterman TG; Bijlsma JJ; de Jongh CE; Kuipers OP; Hermans PW
J Bacteriol 2007 ;189(18):6540-6550 pubmedlink 17631629 2007 |
Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis.
Smits WK; Bongiorni C; Veening JW; Hamoen LW; Kuipers OP; Perego M
Mol Microbiol 2007 ;65(1):103-20 pubmedlink 17581123 2007 |
Identification of a novel streptococcal gene cassette mediating SOS mutagenesis in Streptococcus uberis.
Varhimo E; Savijoki K; Jalava J; Kuipers OP; Varmanen P
J Bacteriol 2007 ;189(14):5210-22 pubmedlink 17513475 2007 |
Enhanced production of pediocin PA-1 in wild nisin- and non-nisin-producing Lactococcus lactis strains of dairy
origin
Reviriego C; Fernandez L; Kuipers OP; Kok J; Rodriguez JM
International Dairy Journal 2007 ;17(5):574-577 2007 |
Comparative analyses of prophage-like elements present in two Lactococcus lactis strains.
Ventura M; Zomer A; Canchaya C; O'Connell-Motherway M, Kuipers O, Turrroni F, Ribbera A, Foroni E,
Buist G, Wegmann U, Shearman C, Gasson MJ, Fitzgerald GF, Kok J, van Sinderen D
Appl Environ Microbiol 2007 ;73(23):7771-7780 pubmedlink 17933937 2007 |
NisC, the Cyclase of the Lantibiotic Nisin, Can Catalyze Cyclization of Designed Nonlantibiotic Peptides.
Rink R; Kluskens LD; Kuipers A; Driessen AJ; Kuipers OP; Moll GN
Biochemistry 2007 ;46(45):13179-13189 pubmedlink 17929939 2007 |
Novel surface display system for proteins on non-genetically modified gram-positive bacteria.
Bosma T; Kanninga R; Neef J; Audouy SA; van Roosmalen ML; Steen A; Buist G; Kok J;
Kuipers OP; Robillard G; Leenhouts K
Appl Environ Microbiol 2006 ;72(1):880-9 pubmedlink 16391130 2006 |
Expression of Transcription Activator ComK of Bacillus subtilis in the Heterologous Host Lactococcus lactis
Leads to a Genome-Wide Repression Pattern: a Case Study of Horizontal Gene Transfer.
Susanna KA; den Hengst CD; Hamoen LW; Kuipers OP
Appl Environ Microbiol 2006 ;72(1):404-11 pubmedlink 16391071 2006 |
Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria.
van Roosmalen ML; Kanninga R; El Khattabi M; Neef J; Audouy S; Bosma T; Kuipers A; Post E; Steen A;
Kok J; Buist G; Kuipers OP; Robillard G; Leenhouts K
Methods 2006 ;38(2):144-9 pubmedlink 16414272 2006 |
To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae
Kloosterman TG; Bijlsma JJ; Kok J; Kuipers OP
Microbiology 2006 ;152(0):351-9 pubmedlink 16436423 2006 |
Phenotypic variation in bacteria: the role of feedback regulation.
Smits WK; Kuipers OP; Veening JW
Nat Rev Microbiol 2006 ;4(4):259-71 pubmedlink 16541134 2006 |
Transformation of undomesticated strains of Bacillus subtilis by protoplast electroporation.
Romero D; Perez-Garcia A; Veening JW; de Vicente A; Kuipers OP
J Microbiol Methods 2006 ;66(3):556-559 pubmedlink 16503058 2006 |
Effects of Phosphorelay Perturbations on Architecture, Sporulation, and Spore Resistance in Biofilms of
Bacillus subtilis.
Veening JW; Kuipers OP; Brul S; Hellingwerf KJ; Kort R
J Bacteriol 2006 ;188(8):3099-109 pubmedlink 16585769 2006 |
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations.
Ramasamy R; Yasawardena S; Zomer A; Venema G; Kok J; Leenhouts K
Vaccine 2006 ;24(18):3900-8 pubmedlink 16545511 2006 |
LmrCD is a major multidrug resistance transporter in Lactococcus lactis.
Lubelski J; de Jong A; van Merkerk R; Agustiandari H; Kuipers OP; Kok J; Driessen AJ
Mol Microbiol 2006 ;61(3):771-81 pubmedlink 16879641 2006 |
Single cell analysis of gene expression patterns of competence development and initiation of sporulation in
Bacillus subtilis grown on chemically defined media.
Veening JW; Smits WK; Hamoen LW; Kuipers OP
J Appl Microbiol 2006 ;101(3):531-41 pubmedlink 16907804 2006 |
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.
Hasper HE; Kramer NE; Smith JL; Hillman JD; Zachariah C; Kuipers OP; de Kruijff B; Breukink E
Science 2006 ;313(5793):1636-7 pubmedlink 16973881 2006 |
Natural sweetening of food products by engineering Lactococcus lactis for glucose production.
Pool WA; Neves AR; Kok J; Santos H; Kuipers OP
Metab Eng 2006 ;8(5):456-64 pubmedlink 16844396 2006 |
Different subcellular locations of secretome components of Gram-positive bacteria.
Buist G; Ridder AN; Kok J; Kuipers OP
Microbiology 2006 ;152(0):2867-74 pubmedlink 17005968 2006 |
The a-phosphoglucomutase of lactococcus lactis is unrelated to the a-D-phosphohexomutase superfamily and
encoded by the essential gene pgmH.
Neves AR; Pool WA; Castro R; Mingote A; Santos F; Kok J; Kuipers OP; Santos H
J Biol Chem 2006 ;281(48):36864-36873 pubmedlink 16980299 2006 |
BAGEL: a web-based bacteriocin genome mining tool.
de Jong A; van Hijum SA; Bijlsma JJ; Kok J; Kuipers OP
Nucleic Acids Res 2006 ;34(0):0-9 pubmedlink 16845009 2006 |
GlnR-mediated regulation of nitrogen metabolism in Lactococcus lactis.
Larsen R; Kloosterman TG; Kok J; Kuipers OP
J Bacteriol 2006 ;188(13):4978-82 pubmedlink 16788206 2006 |
Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae.
Kloosterman TG; Hendriksen WT; Bijlsma JJ; Bootsma HJ; van Hijum SA; Kok J; Hermans PW;
Kuipers OP
J Biol Chem 2006 ;281(35):25097-109 pubmedlink 16787930 2006 |
High-level heterologous production and functional expression of the sec-dependent enterocin P from
Enterococcus faecium P13 in Lactococcus lactis.
Gutierrez J; Larsen R; Cintas LM; Kok J; Hernandez PE
Appl Microbiol Biotechnol 2006 ;72(1):41-51 pubmedlink 16416297 2006 |
Transcriptome analysis reveals mechanisms by which Lactococcus lactis acquires nisin resistance.
Kramer NE; van Hijum SA; Knol J; Kok J; Kuipers OP
Antimicrob Agents Chemother 2006 ;50(5):1753-61 pubmedlink 16641446 2006 |
Identification and functional characterization of the Lactococcus lactis CodY-regulated branched-chain amino
acid permease BcaP (CtrA).
den Hengst CD; Groeneveld M; Kuipers OP; Kok J
J Bacteriol 2006 ;188(9):3280-9 pubmedlink 16621821 2006 |
SIMAGE: simulation of DNA-microarray gene expression data.
Albers CJ; Jansen RC; Kok J; Kuipers OP; van Hijum SA
BMC Bioinformatics 2006 ;7(0):205-0 pubmedlink 16613602 2006 |
Characterization of the lytic-lysogenic switch of the lactococcal bacteriophage Tuc2009.
Kenny JG; Leach S; de la Hoz AB; Venema G; Kok J; Fitzgerald GF; Nauta A; Alonso JC; van Sinderen D
Virology 2006 ;347(2):434-46 pubmedlink 16410016 2006 |
Functional analysis of the competence transcription factor ComK of Bacillus subtilis by characterization of
truncation variants.
Susanna KA; Fusetti F; Thunnissen AM; Hamoen LW; Kuipers OP
Microbiology 2006 ;152(0):473-83 pubmedlink 16436435 2006 |
Mutations in Lactococcus lactis and their Detection
Kok, J.; Van den Burg, B.
Genetically Engineered Food, Methods and Detection (ed. Knut J. Heller) 2006 ;0(0):248-268 - 2006 |
Mapping the pathways to staphylococcal pathogenesis by comparative secretomics.
Sibbald MJ; Ziebandt AK; Engelmann S; Hecker M; de Jong A; Harmsen HJ; Raangs GC; Stokroos I; Arends JP;
Dubois JY; van Dijl JM
Microbiol Mol Biol Rev 2006 ;70(3):755-88 pubmedlink 16959968 2006 |
A Disulfide Bond-Containing Alkaline Phosphatase Triggers a BdbC-Dependent Secretion Stress Response in
Bacillus subtilis.
Darmon E; Dorenbos R; Meens J; Freudl R; Antelmann H; Hecker M; Kuipers OP; Bron S; Quax WJ; Dubois
JY; van Dijl JM
Appl Environ Microbiol 2006 ;72(11):6876-85 pubmedlink 17088376 2006 |
SEC-MEDIATED TRANSPORT OF POST-TRANSLATIONALLY DEHYDRATED PEPTIDES IN LACTOCOCCUS LACTIS.
Kuipers A; Wierenga J; Rink R; Kluskens LD; Driessen AJ; Kuipers OP; Moll GN
Appl Environ Microbiol 2006 ;72(12):7626-7633 pubmedlink 17041158 2006 |
MOVE: A Multi-level Ontology-based Visualization and Exploration framework for genomic networks
Bosman,D.W.J.;Blom,E.J.;Ogao,P.J.;Kuipers,O.P.;Roerdink,J.B.T.M.
In Silico Biology 2006 ;7(0):0-0 2006 |
Iron starvation triggers the stringent response and induces amino acid biosynthesis for bacillibactin production
in Bacillus subtilis.
Miethke M; Westers H; Blom EJ; Kuipers OP; Marahiel MA
J Bacteriol 2006 ;188(24):8655-7 pubmedlink 17012385 2006 |
Comparative and functional genomics of lactococci.
Kok J; Buist G; Zomer AL; van Hijum SA; Kuipers OP
FEMS Microbiol Rev 2005 ;29(3):411-33 pubmedlink 15936843 2005 |
Development and characterization of a subtilin-regulated expression system in Bacillus subtilis: strict
control of gene expression by addition of subtilin.
Bongers RS; Veening JW; Van Wieringen M; Kuipers OP; Kleerebezem M
Appl Environ Microbiol 2005 ;71(12):8818-24 pubmedlink 16332878 2005 |
Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies.
van Hijum SA; Zomer AL; Kuipers OP; Kok J
Nucleic Acids Res 2005 ;33(0):0-6 pubmedlink 15980536 2005 |
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.
Rink R; Kuipers A; de Boef E; Leenhouts KJ; Driessen AJ; Moll GN; Kuipers OP
Biochemistry 2005 ;44(24):8873-82 pubmedlink 15952794 2005 |
Post-translational Modification of Therapeutic Peptides By NisB, the Dehydratase of the Lantibiotic Nisin.
Kluskens LD; Kuipers A; Rink R; de Boef E; Fekken S; Driessen AJ; Kuipers OP; Moll GN
Biochemistry 2005 ;44(38):12827-12834 pubmedlink 16171398 2005 |
Overview on sugar metabolism and its control in Lactococcus lactis . The input from in vivo NMR.
Neves AR; Pool WA; Kok J; Kuipers OP; Santos H
FEMS Microbiol Rev 2005 ;0(0):0-0 - pubmedlink 15939503 2005 |
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper
functioning.
Steen A; Buist G; Horsburgh GJ; Venema G; Kuipers OP; Foster SJ; Kok J
FEBS J 2005 ;272(11):2854-68 pubmedlink 15943817 2005 |
Tricksy business: transcriptome analysis reveals the involvement of thioredoxin A in redox homeostasis, oxidative
stress, sulfur metabolism, and cellular differentiation in Bacillus subtilis.
Smits WK; Dubois JY; Bron S; van Dijl JM; Kuipers OP
J Bacteriol 2005 ;187(12):3921-30 pubmedlink 15937154 2005 |
Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and
DNA-binding site.
Barriere C; Veiga-da-Cunha M; Pons N; Guedon E; van Hijum SA; Kok J; Kuipers OP; Ehrlich DS;
Renault P
J Bacteriol 2005 ;187(11):3752-61 pubmedlink 15901699 2005 |
Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis.
Veening JW; Hamoen LW; Kuipers OP
Mol Microbiol 2005 ;56(6):1481-94 pubmedlink 15916600 2005 |
A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality
of DNA-microarray data.
van Hijum SA; de Jong A; Baerends RJ; Karsens HA; Kramer NE; Larsen R; den
Hengst CD; Albers CJ; Kok J; Kuipers OP
BMC Genomics 2005 ;6(1):77-0 pubmedlink 15907200 2005 |
Interaction between ArgR and AhrC controls regulation of arginine metabolism in Lactococcus lactis.
Larsen R; Kok J; Kuipers OP
J Biol Chem 2005 ;280(19):19319-30 pubmedlink 15749710 2005 |
Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development.
Smits WK; Eschevins CC; Susanna KA; Bron S; Kuipers OP; Hamoen LW
Mol Microbiol 2005 ;56(3):604-14 pubmedlink 15819618 2005 |
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
Albano M; Smits WK; Ho LT; Kraigher B; Mandic-Mulec I; Kuipers OP; Dubnau D
J Bacteriol 2005 ;187(6):2010-9 pubmedlink 15743949 2005 |
Probing direct interactions between CodY and the oppD promoter of Lactococcus lactis.
den Hengst CD; Curley P; Larsen R; Buist G; Nauta A; van Sinderen D; Kuipers OP; Kok J
J Bacteriol 2005 ;187(2):512-21 pubmedlink 15629923 2005 |
Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids.
Steen A; Palumbo E; Deghorain M; Cocconcelli PS; Delcour J; Kuipers OP; Kok J; Buist G;
Hols P
J Bacteriol 2005 ;187(1):114-24 pubmedlink 15601695 2005 |
Lactic acid bacteria - Genetics, metabolism and application
de Vos WM; Kleerebezem M; Kuipers OP
FEMS Microbiol Rev 2005 ;29(3):391-391 pubmedlink 15939504 2005 |
Bacillus subtilis alpha-phosphoglucomutase is required for normal cell morphology and biofilm formation.
Lazarevic V; Soldo B; Medico N; Pooley H; Bron S; Karamata D
Appl Environ Microbiol 2005 ;71(1):39-45 pubmedlink 15640167 2005 |
Alternative lactose catabolic pathway in Lactococcus lactis IL1403.
Aleksandrzak-Piekarczyk T; Kok J; Renault P; Bardowski J
Appl Environ Microbiol 2005 ;71(10):6060-9 pubmedlink 16204522 2005 |
Specificity and selectivity determinants of peptide transport in Lactococcus lactis and other microorganisms.
Doeven MK; Kok J; Poolman B
Mol Microbiol 2005 ;57(3):640-9 pubmedlink 16045610 2005 |
The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element.
den Hengst CD; van Hijum SA; Geurts JM; Nauta A; Kok J; Kuipers OP
J Biol Chem 2005 ;280(40):34332-42 pubmedlink 16040604 2005 |
Ripening of gouda cheese using genetically modified Lactococcus lactis starters
Bockelmann, W; Golecki, S; Kok, J; Mierau, I; Heller, KJ
Kieler Milchwirtschaftliche Forschungsberichte 2005 ;57(0):263-272 2005 |
ArgR and AhrC are both required for regulation of arginine metabolism in Lactococcus lactis.
Larsen R; Buist G; Kuipers OP; Kok J
J Bacteriol 2004 ;186(4):1147-57 pubmedlink 14762010 2004 |
Mechanism of transcription activation at the comG promoter by the competence transcription factor ComK of
Bacillus subtilis.
Susanna KA; van der Werff AF; den Hengst CD; Calles B; Salas M; Venema G; Hamoen LW; Kuipers
OP
J Bacteriol 2004 ;186(4):1120-8 pubmedlink 14762007 2004 |
Differential expression of two paralogous genes of Bacillus subtilis encoding single-stranded DNA binding
protein.
Lindner C; Nijland R; van Hartskamp M; Bron S; Hamoen LW; Kuipers OP
J Bacteriol 2004 ;186(4):1097-105 pubmedlink 14762004 2004 |
Engineering of quorum-sensing systems for improved production of alkaline protease by Bacillus subtilis.
Tjalsma H; Koetje EJ; Kiewiet R; Kuipers OP; Kolkman M; van der Laan J; Daskin R; Ferrari E; Bron
S
J Appl Microbiol 2004 ;96(3):569-78 pubmedlink 14962137 2004 |
Genomics and bioinformatics enhance research on food and gut bacteria.
Kuipers OP
Curr Opin Biotechnol 2004 ;15(2):83-5 pubmedlink 15081043 2004 |
Genome2D: a visualization tool for rapid analysis of bacterial transcriptome data.
Baerends, R.J.S.; Smits, W.K.; de Jong, A.; Hamoen, L.W.; Kok, J.; Kuipers, O.P.
Genome Biology 2004 ;5(5):1-6 pubmedlink 15128451 2004 |
Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics
databases.
Swertz MA; (Bert) De Brock EO; Van Hijum SA; De Jong A; Buist G; Baerends RJ; Kok J;
Kuipers OP; Jansen RC
Bioinformatics 2004 ;20(0):2075-2083 pubmedlink 15059831 2004 |
Proteomics of Protein Secretion by Bacillus subtilis: Separating the \"Secrets\" of the Secretome.
Tjalsma H; Antelmann H; Jongbloed JD; Braun PG; Darmon E; Dorenbos R; Dubois JY; Westers H; Zanen G; Quax
WJ; Kuipers OP; Bron S; Hecker M; Van Dijl JM
Microbiol Mol Biol Rev 2004 ;68(2):207-33 pubmedlink 15187182 2004 |
The Bacillus secretion stress response is an indicator for alpha-amylase production levels.
Westers H; Darmon E; Zanen G; Veening JW; Kuipers OP; Bron S; Quax WJ; Van Dijl JM
Lett Appl Microbiol 2004 ;39(1):65-73 pubmedlink 15189290 2004 |
Subcellular sites for bacterial protein export.
Campo N; Tjalsma H; Buist G; Stepniak D; Meijer M; Veenhuis M; Westermann M; Muller JP; Bron S;
Kok J; Kuipers OP; Jongbloed JD
Mol Microbiol 2004 ;53(6):1583-99 pubmedlink 15341641 2004 |
Resistance of Gram-positive bacteria to nisin is not determined by Lipid II levels.
Kramer NE; Smid EJ; Kok J; De Kruijff B; Kuipers OP; Breukink E
FEMS Microbiol Lett 2004 ;239(1):157-161 pubmedlink 15451114 2004 |
The circular bacteriocins gassericin A and circularin A.
Kawai Y; Kemperman R; Kok J; Saito T
Curr Protein Pept Sci 2004 ;5(5):393-8 pubmedlink 15544534 2004 |
Two homologous oligopeptide binding protein genes (oppA) in Lactococcus lactis opp2 [corrected]
Sanz Y; Lanfermeijer FC; Hellendoorn M; Kok J; Konings WN; Poolman B
Int J Food Microbiol 2004 ;97(1):9-15 pubmedlink 15527913 2004 |
Two minimal Tat translocases in Bacillus.
Jongbloed JD; Grieger U; Antelmann H; Hecker M; Nijland R; Bron S; van Dijl JM
Mol Microbiol 2004 ;54(5):1319-25 pubmedlink 15554971 2004 |
A plasmid-borne Rap-Phr system of Bacillus subtilis can mediate cell-density controlled production of extracellular
proeases
Koetje, J.E.; Hajdo-Milasinovic, A.; Kiewiet, R.; Bron, S.; Tjalsma, H.
Microbiology 2003 ;149(0):19-28 2003 |
Controlling competence in Bacillus subtilis: shared use of regulators.
Hamoen LW; Venema G; Kuipers OP
Microbiology 2003 ;149(0):9-17 pubmedlink 12576575 2003 |
The Structure of the Transposable Genetic Element ISBsu2 in the Cryptic Plasmid p1516 from a Soil Bacillus subtilis
Strain and the Presence of Homologues of This Element in the Chromosomes of Various Bacillus subtilis Strains
Holsappel, S.; Gagarina, E.Yu.; Poluektova, E.U.; Nezametdinova, V.z.; Gel'fand, M.S.; Prozorov, A.A.; Bron, S.
Microbiology 2003 ;72(0):58-63 2003 |
Identification and Characterization of Two Novel Clostridial Bacteriocins, Circularin A and Closticin 574
Kemperman, R. ; Kuipers, A. ; Karsens, H. ; Nauta, A. ; Kuipers, O. and Kok, J.
Applied and Environmental Microbiology 2003 ;69(0):1589-1597 2003 |
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall
constituents.
Steen A; Buist G; Leenhouts KJ; El Khattabi M; Grijpstra F; Zomer AL; Venema G; Kuipers
OP; Kok J
J Biol Chem 2003 ;278(26):23874-81 pubmedlink 12684515 2003 |
Functional analysis of the gene cluster involved in production of the bacteriocin circularin A by Clostridium
beijerinckii ATCC 25752.
Kemperman R; Jonker M; Nauta A; Kuipers OP; Kok J
Appl Environ Microbiol 2003 ;69(10):5839-48 pubmedlink 14532033 2003 |
Projector: automatic contig mapping for gap closure purposes.
van Hijum SA; Zomer AL; Kuipers OP; Kok J
Nucleic Acids Res 2003 ;31(22):0-0 pubmedlink 14602937 2003 |
UniFrag and GenomePrimer: selection of primers for genome-wide production of unique amplicons.
van Hijum SA; de Jong A; Buist G; Kok J; Kuipers OP
Bioinformatics 2003 ;19(12):1580-2 pubmedlink 12912842 2003 |
Novel mechanism of bacteriocin secretion and immunity carried out by lactococcal multidrug resistance
proteins.
Gajic O; Buist G; Kojic M; Topisirovic L; Kuipers OP; Kok J
J Biol Chem 2003 ;278(36):34291-8 pubmedlink 12801935 2003 |
Purification and characterisation of a lactococcal aminoacylase.
Curley P; van der Does C; Driessen AJ; Kok J; van Sinderen D
Arch Microbiol 2003 ;179(6):402-8 pubmedlink 12682714 2003 |
Genome engineering reveals large dispensable regions in Bacillus subtilis.
Westers H; Dorenbos R; van Dijl JM; Kabel J; Flanagan T; Devine KM; Jude F; Seror SJ; Beekman AC; Darmon E;
Eschevins C; de Jong A; Bron S; Kuipers OP; Albertini AM; Antelmann H; Hecker M; Zamboni N;
Sauer U; Bruand C; Ehrlich DS; Alonso JC; Salas M; Quax WJ
Mol Biol Evol 2003 ;20(12):2076-90 pubmedlink 12949151 2003 |
The extracellular proteome of Bacillus subtilis under secretion stress conditions.
Antelmann H; Darmon E; Noone D; Veening JW; Westers H; Bron S; Kuipers OP; Devine KM;
Hecker M; van Dijl JM
Mol Microbiol 2003 ;49(1):143-56 pubmedlink 12823817 2003 |
Complete genome sequence of Lactobacillus plantarum WCFS1.
Kleerebezem M; Boekhorst J; van Kranenburg R; Molenaar D; Kuipers OP; Leer R; Tarchini R; Peters SA;
Sandbrink HM; Fiers MW; Stiekema W; Lankhorst RM; Bron PA; Hoffer SM; Groot MN; Kerkhoven R; de Vries
M; Ursing B; de Vos WM; Siezen RJ
Proc Natl Acad Sci U S A 2003 ;100(4):1990-5 pubmedlink 12566566 2003 |
Complementary impact of paralogous Oxa1-like proteins of Bacillus subtilis on post-translocational stages in
protein secretion.
Tjalsma H; Bron S; van Dijl JM
J Biol Chem 2003 ;278(18):15622-32 pubmedlink 12586834 2003 |
Essential Bacillus subtilis genes.
Kobayashi K; Ehrlich SD; Albertini A; Amati G; Andersen KK; Arnaud M; Asai K; Ashikaga S; Aymerich S; Bessieres P;
Boland F; Brignell SC; Bron S; Bunai K; Chapuis J; Christiansen LC; Danchin A; Debarbouille M; Dervyn E;
Deuerling E; Devine K; Devine SK; Dreesen O; Errington J; Fillinger S; Foster SJ; Fujita Y; Galizzi A; Gardan R;
Eschevins C; Fukushima T; Haga K; Harwood CR; Hecker M; Hosoya D; Hullo MF; Kakeshita H; Karamata D; Kasahara Y;
Kawamura F; Koga K; Koski P; Kuwana R; Imamura D; Ishimaru M; Ishikawa S; Ishio I; Le Coq D; Masson A; Mauel C;
Meima R; Mellado RP; Moir A; Moriya S; Nagakawa E; Nanamiya H; Nakai S; Nygaard P; Ogura M; Ohanan T; O\
Proc Natl Acad Sci U S A 2003 ;100(8):4678-83 pubmedlink 12682299 2003 |
Active lipoprotein precursors in the Gram-positive eubacterium Lactococcus lactis.
Venema R; Tjalsma H; van Dijl JM; de Jong A; Leenhouts K; Buist G; Venema G
J Biol Chem 2003 ;278(17):14739-46 pubmedlink 12584195 2003 |
Genetically Engineered Food, Methods and Detection (ed. Knut F. Heller)
Kok, J.; Van den Burg, B.
Wiley-VCH GmbH & Co. KgaA, Weinheim, Germany 2003 ;0(0):231-250 - 2003 |
Genetics of Lactic Acid Bacteria (ed. B. Wood)
Kok, J.; Buist, G.
Kluwer, New York 2003 ;0(0):189-223 - 2003 |
MicroPreP: a cDNA microarray data pre-processing framework
van Hijum, S.A.F.T., Garcia de la Nava, J., Trelles, O., Kok, J., Kuipers, O.P.
Applied Bioinformatics 2003 ;2(4):241-244 pubmedlink 15130795 2003 |
PreP: gene expression data pre-processing.
Garcia de la Nava J; van Hijum S; Trelles O
Bioinformatics 2003 ;19(17):2328-9 pubmedlink 14630668 2003 |
Protein Transport Pathways in Bacillus subtilis: a Genome-Based Road Map
van Dijl, J. M., Bolhuis, A., Tjalsma, H., Jongbloed, J. D., de Jong, A.,Bron, S.
Bacillus subtilis and its Closest Relatives: From Genes to Cells 2002 ;24(0):337-355 2002 |
Regulation of the metC-cysK operon, involved in sulfur metabolism in Lactococcus lactis
Fernandez, M., Kleerebezem, M., Kuipers, O. P., Siezen, R. J.,van Kranenburg, R.
J Bacteriol 2002 ;184(1):82-90 2002 |
The effects of modifying the suface charge on the catalytic activity of a thermolysin-like protease.
de Kreij,A.;van den Burg,B.;Venema,G.;Vriend,G.;Eijsink,V.G.;Nielsen,J.E.
J.Biol.Chem. 2002 ;277(18):15432-15438 2002 |
Transcriptome analysis and related databases of Lactococcus lactis
Kuipers, O.P., de Jong, A., Baerends, R.J.S., van Hijum, S.A.F.T., Zomer, A.L., Karsens, H.A., den Hengst, C.D.,
Kramer, N.E., Buist, B., Kok, J.
Antonie van Leeuwenhoek 2002 ;82(0):113-122 2002 |
Pediocin PA-1, a Wide-Spectrum Bacteriocin from Lactic Acid Bacteria
Rodriguez, J. M., Martinez, M. I., Kok, J.
Critical Revieuws in Food Science and Nutrition 2002 ;42(0):91-121 2002 |
Discovering lactic acid bacteria by genomics
Klaenhammer, T., Kuipers. O., Kok. J. Et al.
Antonie van Leeuwenhoek 2002 ;82(0):29-58 2002 |
Characterization of the putative replisome organizer of the lactococcal bacteriophage r1t.: Zuniga M,
Franke-Fayard B, Venema G, Kok J, Nauta A. Related Articles, Links
Zuniga M, Franke-Fayard B, Venema G, Kok J, Nauta A.
J Virol. 2002 ;76(20):10234-10244 2002 |
Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis
using a genomic approach.
Hamoen LW; Smits WK; Jong Ad A; Holsappel S; Kuipers OP
Nucleic Acids Res 2002 ;30(24):5517-28 2002 |
The presence of the transposable element ISBsu2 from a cryptic plasmid in chromosomes of some Bacillus
subtilis strains.
Poluektova EU; Holsappel S; Gagarina EY; Gelfand MS; Bron S; Prozorov AA
Dokl Biochem Biophys 2002 ;386(0):275-7 pubmedlink 12474766 2002 |
Bacillus subtilis functional genomics: genome-wide analysis of the DegS-DegU regulon by transcriptomics and
proteomics.
Mader U; Antelmann H; Buder T; Dahl MK; Hecker M; Homuth G
Mol Genet Genomics 2002 ;268(4):455-67 pubmedlink 12471443 2002 |
Selective contribution of the twin-arginine translocation pathway to protein secretion in Bacillus subtilis.
Jongbloed JD; Antelmann H; Hecker M; Nijland R; Bron S; Airaksinen U; Pries F; Quax WJ; van Dijl JM;
Braun PG
J Biol Chem 2002 ;277(46):44068-78 pubmedlink 12218047 2002 |
Functional genomic analysis of the Bacillus subtilis Tat pathway for protein secretion.
van Dijl JM; Braun PG; Robinson C; Quax WJ; Antelmann H; Hecker M; Muller J; Tjalsma H; Bron S; Jongbloed JD
J Biotechnol 2002 ;98(2):243-54 pubmedlink 12141990 2002 |
Positive role of peptidoglycan breaks in lactococcal biofilm formation.
Mercier C; Durrieu C; Briandet R; Domakova E; Tremblay J; Buist G; Kulakauskas S
Mol Microbiol 2002 ;46(1):235-43 pubmedlink 12366846 2002 |
A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress.
Hyyrylainen HL; Bolhuis A; Darmon E; Muukkonen L; Koski P; Vitikainen M; Sarvas M; Pragai Z; Bron S; van
Dijl JM; Kontinen VP
Mol Microbiol 2001 ;41(5):1159-72 pubmedlink 11555295 2001 |
A proteomic view on genome-based signal peptide predictions
Antelmann, H., Tjalsma, H., Voigt, B., Ohlmeier, S., Bron, S., van Dijl, J. M.,Hecker, M.
Genome Res 2001 ;11(9):1484-1502 2001 |
A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one
sensor-transmitter
Kleerebezem, M., Kuipers, O. P., de Vos, W. M., Stiles, M. E.,Quadri, L. E.
Peptides 2001 ;22(10):1597-1601 2001 |
Activation of silent gal genes in the lac-gal regulon of Streptococcus thermophilus
Vaughan, E. E., van den Bogaard, P. T., Catzeddu, P., Kuipers, O. P.,de Vos, W. M.
J Bacteriol 2001 ;183(4):1184-1194 2001 |
Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline
phosphatases
Pragai, Z., Eschevins, C., Bron, S.,Harwood, C. R.
J Bacteriol 2001 ;183(8):2505-2515 2001 |
Casitone-mediated expression of the prtP and prtM genes in Lactococcus lactis subsp. lactis BGIS29.
Miladinov N; Kuipers OP; Topisirovic L
Arch Microbiol 2001 ;177(1):54-61 pubmedlink 11797045 2001 |
Cell processes and macromolecule metabolism: a quest for genes involved in genetic competence, DNA recombination
and repair.
Meima, R., Eschevins, C.,Bron, S.
Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):123-129 - 2001 |
Cell processes and macromolecule metabolism: Methods for the selection of mutants in genetic competence, DNA
recombination and repair, and protein secretion
Meima, R., Eschevins, C.,Bron, S.
Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):131-136 - 2001 |
Cold shock proteins of Lactococcus lactis MG1363 are involved in cryoprotection and in the production of
cold-induced proteins
Wouters, J. A., Frenkiel, H., de Vos, W. M., Kuipers, O. P.,Abee, T.
Appl Environ.Microbiol 2001 ;67(11):5171-5178 2001 |
Complete DNA sequence of Lactococcus lactis adds flavor to genomics
Kuipers, O. P.
Genome Res 2001 ;11(5):673-674 2001 |
Detergent-independent in vitro activity of a truncated Bacillus signal peptidase
van Roosmalen, M. L., Jongbloed, J. D., de Jong, A., van Eerden, J., Venema, G., Bron, S.,van Dijl, J. M.
Microbiology 2001 ;147(0):909-917 2001 |
Distinction between major and minor Bacillus signal peptidases based on phylogenetic and structural criteria
van Roosmalen, M. L., Jongbloed, J. D., Dubois, J. Y., Venema, G., Bron, S.,van Dijl, J. M.
J Biol Chem 2001 ;276(27):25230-25235 2001 |
Hierarchical control versus autoregulation of carbohydrate utilization in bacteria.
Gunnewijk MG; van den Bogaard PT; Veenhoff LM; Heuberger EH; de Vos WM; Kleerebezem M; Kuipers OP; Poolman B
J Mol Microbiol Biotechnol 2001 ;3(3):401-13 pubmedlink 11361071 2001 |
Membrane topology of the Streptomyces lividans type I signal peptidases
Geukens, N., Lammertyn, E., van Mellaert, L., Schacht, S., Schaerlaekens, K., Parro, V., Bron, S., Engelborghs, Y.,
Mellado, R. P.,Anne, J.
J Bacteriol 2001 ;183(16):4752-4760 2001 |
Molecular tools for the identification of mutations affecting protein secretion.
Meima, R., Eschevins, C., Koski, P., Sarvas, M.,Bron, S.
Functional analysis of bacterial genes: A practical manual. 2001 ;0(0):137-143 - 2001 |
Proteins of the lactococcin A secretion system: lcnD encodes two in-frame proteins
Varcamonti, M., Nicastro, G., Venema, G.,Kok, J.
FEMS Microbiol Lett. 2001 ;204(2):259-263 2001 |
Regulation of bacteriocin production in Lactobacillus plantarum depends on a conserved promoter arrangement with
consensus binding sequence
Risoen, P. A., Johnsborg, O., Diep, D. B., Hamoen, L. W., Venema, G.,Nes, I. F.
Mol Genet Genomics 2001 ;265(1):198-206 2001 |
Regulatory functions of serine-46-phosphorylated HPr in Lactococcus lactis
Monedero, V., Kuipers, O. P., Jamet, E.,Deutscher, J.
J Bacteriol 2001 ;183(11):3391-3398 2001 |
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell
wall biosynthesis for potent antibiotic activity
Wiedemann, I., Breukink, E., van Kraaij, C., Kuipers, O. P., Bierbaum, G., de Kruijff, B.,Sahl, H. G.
J Biol Chem 2001 ;276(3):1772-1779 2001 |
Structural and functional analysis of a bipolar replication terminus. Implications for the origin of polarity of
fork arrest
Mohanty, B. K., Bussiere, D. E., Sahoo, T., Pai, K. S., Meijer, W. J., Bron, S.,Bastia, D.
J Biol Chem 2001 ;276(16):13160-13168 2001 |
The Bacillus subtilis competence transcription factor, ComK, overrides LexA-imposed transcriptional inhibition
without physically displacing LexA
Hamoen, L. W., Haijema, B. J., Bijlsma, J. J., Venema, G.,Lovett, C. M.
J Biol Chem 2001 ;276(46):42901-42907 2001 |
The effect of changing the hydrophobic S1' subsite of thermolysin-like proteases on substrate specificity
de Kreij, A., van den Burg, B., Veltman, O. R., Vriend, G., Venema, G.,Eijsink, V. G.
Eur.J Biochem 2001 ;268(18):4985-4991 2001 |
The Eubacterial Lipoprotein-Specific (Type II) Signal Peptidase
Tjalsma, H., Zanen, G., Bron, S.,van Dijl, J. M.
The Enzymes 2001 ;0(0):3-26 - 2001 |
A truncated soluble Bacillus signal peptidase produced in Escherichia coli is subject to self-cleavage at its
active site
van Roosmalen, M. L., Jongbloed, J. D., Kuipers, A., Venema, G., Bron, S.,van Dijl, J. M.
J Bacteriol 2000 ;182(20):5765-5770 2000 |
Bile salt hydrolase of Bifidobacterium longum-biochemical and genetic characterization
Tanaka, H., Hashiba, H., Kok, J.,Mierau, I.
Appl Environ.Microbiol 2000 ;66(6):2502-2512 2000 |
Biological and molecular characterization of a two-peptide lantibiotic produced by Lactococcus lactis IFPL105
Martinez-Cuesta, M. C., Buist, G., Kok, J., Hauge, H. H., Nissen-Meyer, J., Pelaez, C.,Requena, T.
J Appl Microbiol 2000 ;89(2):249-260 2000 |
Changes in glycolytic activity of Lactococcus lactis induced by low temperature
Wouters, J. A., Kamphuis, H. H., Hugenholtz, J., Kuipers, O. P., de Vos, W. M.,Abee, T.
Appl Environ.Microbiol 2000 ;66(9):3686-3691 2000 |
Chaperone-like activities of the CsaA protein of Bacillus subtilis
Muller, J.P., Bron, S., Venema, G.,van Dijl, J.M.
Microbiology 2000 ;146(1):77-88 2000 |
Cloning, characterization, controlled overexpression, and inactivation of the major tributyrin esterase gene of
Lactococcus lactis
Fernandez, L., Beerthuyzen, M. M., Brown, J., Siezen, R. J., Coolbear, T., Holland, R.,Kuipers, O. P.
Appl Environ.Microbiol 2000 ;66(4):1360-1368 2000 |
Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus
subtilis
Tjalsma, H., Stover, A.G., Driks, A., Venema, G., Bron, S.,van Dijl, J.M.
J Biol Chem 2000 ;275(33):25102-25108 2000 |
Control of lactose transport, beta-galactosidase activity, and glycolysis by CcpA in Streptococcus thermophilus:
evidence for carbon catabolite repression by a non-phosphoenolpyruvate-dependent phosphotransferase system sugar
van den Bogaard, P. T., Kleerebezem, M., Kuipers, O. P.,de Vos, W. M.
J Bacteriol 2000 ;182(21):5982-5989 2000 |
Current strategies for improving food bacteria
Kuipers, O. P., Buist, G.,Kok, J.
Res Microbiol 2000 ;151(10):815-822 2000 |
Did the mitochondrial processing peptidase evolve from a eubacterial regulator of gene expression?
Bolhuis, A., Koetje, E., Dubois, J. Y., Vehmaanpera, J., Venema, G., Bron, S.,van Dijl, J. M.
Mol Biol Evol. 2000 ;17(1):198-201 2000 |
Engineering a disulfide bond and free thiols in the lantibiotic nisin Z
van Kraaij, C., Breukink, E., Rollema, H. S., Bongers, R. S., Kosters, H. A., de Kruijff, B.,Kuipers, O. P.
Eur.J Biochem 2000 ;267(3):901-909 2000 |
Expression of the neutral protease gene from a thermophilic Bacillus sp. BT1 strain in Bacillus subtilis and its
natural host: identification of a functional promoter
Vecerek, B.Venema, G.
J Bacteriol 2000 ;182(14):4104-4107 2000 |
Heterologous coproduction of enterocin A and pediocin PA-1 by Lactococcus lactis: detection by specific
peptide-directed antibodies
Martinez, J. M., Kok, J., Sanders, J. W.,Hernandez, P. E.
Appl Environ.Microbiol 2000 ;66(8):3543-3549 2000 |
Lactic acid bacteria: the bugs of the new millennium
Konings, W. N., Kok, J., Kuipers, O. P.,Poolman, B.
Curr Opin Microbiol 2000 ;3(3):276-282 2000 |
Molecular and functional analyses of the metC gene of Lactococcus lactis, encoding cystathionine beta-lyase
Fernandez, M., van Doesburg, W., Rutten, G. A., Marugg, J. D., Alting, A. C., van Kranenburg, R.,Kuipers, O. P.
Appl Environ.Microbiol 2000 ;66(1):42-48 2000 |
Physiological and regulatory effects of controlled overproduction of five cold shock proteins of Lactococcus lactis
MG1363
Wouters, J. A., Mailhes, M., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T.
Appl Environ.Microbiol 2000 ;66(9):3756-3763 2000 |
Requirement of autolytic activity for bacteriocin-induced lysis
Martinez-Cuesta, M. C., Kok, J., Herranz, E., Pelaez, C., Requena, T.,Buist, G.
Appl Environ.Microbiol 2000 ;66(8):3174-3179 2000 |
Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome
Tjalsma, H., Bolhuis, A., Jongbloed, J. D., Bron, S.,van Dijl, J. M.
Microbiol Mol Biol Rev 2000 ;64(3):515-547 2000 |
Substrate specificity in the highly heterogeneous M4 peptidase family is determined by a small subset of amino
acids
de Kreij, A., Venema, G.,van den Burg, B.
J Biol Chem 2000 ;275(40):31115-31120 2000 |
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway
Jongbloed, J. D., Martin, U., Antelmann, H., Hecker, M., Tjalsma, H., Venema, G., Bron, S., van Dijl, J. M.,
Müller, J. P.
J Biol Chem 2000 ;275(52):41350-41357 2000 |
The anaerobic (class III) ribonucleotide reductase from Lactococcus lactis. Catalytic properties and allosteric
regulation of the pure enzyme system
Torrents, E., Buist, G., Liu, A., Eliasson, R., Kok, J., Gibert, I., Graslund, A.,Reichard, P.
J Biol Chem 2000 ;275(4):2463-2471 2000 |
The Evolution of Bacterial Plasmids.
Osborn, M., Bron, S., Firth, N., Holsappel, S., Huddleston, A., Kiewiet, R., Meijer, W., Seegers, J. F., Skurray,
R., Terpstra, P., Thomas, C. M., Thorsted, P. B., Tietze, E.,Turner, S. L.
The Horizontal Gene Pool : Bacterial Plasmids and Gene Spread 2000 ;8(0):301-361 2000 |
The membrane-bound H(+)-ATPase complex is essential for growth of Lactococcus lactis
Koebmann, B. J., Nilsson, D., Kuipers, O. P.,Jensen, P. R.
J Bacteriol 2000 ;182(17):4738-4743 2000 |
The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus
subtilis
Hamoen, L. W., van Werkhoven, A. F., Venema, G.,Dubnau, D.
Proc Natl Acad Sci 2000 ;97(16):9246-9251 2000 |
The role of cold-shock proteins in low-temperature adaptation of food-related bacteria.
Wouters JA; Rombouts FM; Kuipers OP; de Vos WM; Abee T
Syst Appl Microbiol 2000 ;23(2):165-73 pubmedlink 10930067 2000 |
Broad-host-range shuttle vectors for screening of regulated promoter activity in viridans group streptococci
Vriesema A.J.M.;Brinkman R.;Kok.J.;Zaat S.A.J.
Applied and Environmental Microbiology 2000 ;66(0):535-542 2000 |
Regulation of carbon catabolism in Lactococcus-lactis
Aleksandsak, T,; Kowalczyk, M,;Kok,J.;Bardoski,J.
Food Biotechnology 2000 ;66(0):17-61 2000 |
Characteristics of the biologically active 35-kDa metalloprotease virulence factor from Listeria
monocytogenes.
Coffey A; van den Burg B; Veltman R; Abee T
J Appl Microbiol 2000 ;88(1):132-41 pubmedlink 10735252 2000 |
Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus.
Sabat A; Kosowska K; Poulsen K; Kasprowicz A; Sekowska A; van Den Burg B; Travis J; Potempa J
Infect Immun 2000 ;68(2):973-6 pubmedlink 10639475 2000 |
Analysis of the role of 7 kDa cold-shock proteins of Lactococcus lactis MG1363 in cryoprotection
Wouters, J. A., Jeynov, B., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T.
Microbiology 1999 ;145(0):3185-3194 1999 |
Anchoring of proteins to lactic acid bacteria
Leenhouts, K. J., Buist, G.,Kok, J.
Antonie Van Leeuwenhoek 1999 ;76(1):367-376 1999 |
Characterization of a novel stable biocatalyst obtained by protein engineering
van den Burg, B., de Kreij, A., Van der Veek, P., Mansfeld, J.,Venema, G.
Biotechnol Appl Biochem 1999 ;30(0):35-40 1999 |
Cold shock proteins and low-temperature response of Streptococcus thermophilus CNRZ302
Wouters, J. A., Rombouts, F. M., de Vos, W. M., Kuipers, O. P.,Abee, T.
Appl Environ.Microbiol 1999 ;65(10):4436-4442 1999 |
Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants
Bolhuis, A., Tjalsma, H., Stephenson, K., Harwood, C. R., Venema, G., Bron, S.,van Dijl, J. M.
J Biol Chem 1999 ;274(22):15865-15868 1999 |
DNA-microarrays and food-biotechnology
Kuipers, O. P., de Jong, A., Holsappel, S., Bron, S., Kok, J.,Hamoen, L. W.
Antonie Van Leeuwenhoek 1999 ;76(1):353-355 1999 |
Effects of gene disruptions in the nisin gene cluster of Lactococcus lactis on nisin production and producer
immunity
Ra, R., Beerthuyzen, M. M., de Vos, W. M., Saris, P. E.,Kuipers, O. P.
Microbiology 1999 ;145(0):1227-1233 1999 |
Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis
Bolhuis, A., Tjalsma, H., Smith, H. E., de Jong, A., Meima, R., Venema, G., Bron, S.,van Dijl, J. M.
Appl Environ.Microbiol 1999 ;65(7):2934-2941 1999 |
From DNA sequence to application: possibilities and complications
Venema, G., Kok, J.,van Sinderen, D.
Antonie Van Leeuwenhoek 1999 ;76(1):3-23 1999 |
Functional analysis of paralogous thiol-disulfide oxidoreductases in Bacillus subtilis
Bolhuis, A., Venema, G., Quax, W. J., Bron, S.,van Dijl, J. M.
J Biol Chem 1999 ;274(35):24531-24538 1999 |
Genomics for food biotechnology: prospects of the use of high-throughput technologies for the improvement of
food microorganisms.
Kuipers OP
Curr Opin Biotechnol 1999 ;10(5):511-6 pubmedlink 10508639 1999 |
Introduction of peptidase genes from Lactobacillus delbrueckii subsp. lactis into Lactococcus lactis and controlled
expression
Wegmann, U., Klein, J. R., Drumm, I., Kuipers, O. P.,Henrich, B.
Appl Environ.Microbiol 1999 ;65(11):4729-4733 1999 |
Molecular characterization of the Lactococcus lactis ptsHI operon and analysis of the regulatory role of HPr.
Luesink EJ; Beumer CM; Kuipers OP; De Vos WM
J Bacteriol 1999 ;181(3):764-71 pubmedlink 9922238 1999 |
Membrane topology of the lactococcal bacteriocin ATP-binding cassette transporter protein LcnC. Involvement of LcnC
in lactococcin a maturation
Franke, C. M., Tiemersma, J., Venema, G.,Kok, J.
J Biol Chem 1999 ;274(13):8484-8490 1999 |
Molecular Biology and Genetics of Bacillus spp.
Bron, S., Meima, R., van Dijl, J. M., Wipat, A.,Harwood, C. R.
Manual of Industrial Microbiology and Biotechnology 1999 ;0(0):392-416 - 1999 |
Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and
processing of secretory proteins
Bolhuis, A., Matzen, A., Hyyrylainen, H. L., Kontinen, V. P., Meima, R., Chapuis, J., Venema, G., Bron, S., Freudl,
R.,van Dijl, J. M.
J Biol Chem 1999 ;274(35):24585-24592 1999 |
The mycosubtilin synthetase of Bacillus subtilis ATCC6633: a multifunctional hybrid between a peptide synthetase,
an amino transferase, and a fatty acid synthase
Duitman, E. H., Hamoen, L. W., Rembold, M., Venema, G., Seitz, H., Saenger, W., Bernhard, F., Reinhardt, R.,
Schmidt, M., Ullrich, C., Stein, T., Leenders, F.,Vater, J.
Proc Natl Acad Sci U S A 1999 ;96(23):13294-13299 1999 |
The plasmid-encoded signal peptidase SipP can functionally replace the major signal peptidases SipS and SipT of
Bacillus subtilis
Tjalsma, H., van den Dolder, J., Meijer, W. J., Venema, G., Bron, S.,van Dijl, J. M.
J Bacteriol 1999 ;181(8):2448-2454 1999 |
The potential active site of the lipoprotein-specific (type II) signal peptidase of Bacillus subtilis
Tjalsma, H., Zanen, G., Venema, G., Bron, S.,van Dijl, J. M.
J Biol Chem 1999 ;274(40):28191-28197 1999 |
The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis.
Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein
Tjalsma, H., Kontinen, V. P., Pragai, Z., Wu, H., Meima, R., Venema, G., Bron, S., Sarvas, M.,van Dijl, J. M.
J Biol Chem 1999 ;274(3):1698-1707 1999 |
Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic
Breukink, E., Wiedemann, I., van Kraaij, C., Kuipers, O. P., Sahl, H.,de Kruijff, B.
Science 1999 ;286(5448):2361-2364 1999 |
Environmental stress responses in Lactococcus lactis
Sanders,J.W., Venema, G., Kok, J.
FEMS Microbioloy Revieuws 1999 ;23(0):483-501 1999 |
Dynamical Analysis of Gene Networks Requires Both mRNA and Protein Expression Information
Hatzimanikatis V.
Metabolic Engineering 1999 ;1(-1):0-0 1999 |
A bacterial signal peptidase enhances processing of a recombinant single chain antibody fragment in insect
cells.
Ailor E; Pathmanathan J; Jongbloed JD; Betenbaugh MJ
Biochem Biophys Res Commun 1999 ;255(2):444-50 pubmedlink 10049728 1999 |
Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein.
Bengtsson J; Tjalsma H; Rivolta C; Hederstedt L
J Bacteriol 1999 ;181(2):685-8 pubmedlink 9882689 1999 |
Characterization of natural isolate Lactococcus lactis subsp. lactis BGMN1-5, a strain producing two bacteriocins
cell-wall-associated proteinase and showing clumping phenotype.
Gajic, O.; Kojic, M; Banina, A; Toposirovic, L.J.
Arch. Biol. Sci., Belgrade 1999 ;51(0):69-78 1999 |
Lantibiotics: biosynthesis, mode of action and applications.
van Kraaij C; de Vos WM; Siezen RJ; Kuipers OP
Nat Prod Rep 1999 ;16(5):575-87 pubmedlink 10584332 1999 |
Characterization of the divergent sacBK and sacAR operons, involved in sucrose utilization by Lactococcus
lactis.
Luesink EJ; Marugg JD; Kuipers OP; de Vos WM
J Bacteriol 1999 ;181(6):1924-6 pubmedlink 10074089 1999 |
A chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation
Sanders, J. W., Leenhouts, K. J., Burghoorn, J., Brands, J. R., Venema, G.,Kok, J.
Mol Microbiol 1998 ;27(2):299-310 1998 |
A single calcium binding site is crucial for the calcium-dependent thermal stability of thermolysin-like
proteases.
Veltman OR; Vriend G; Berendsen HJ; Van den Burg B; Venema G; Eijsink VG
Biochemistry 1998 ;37(15):5312-9 pubmedlink 9548763 1998 |
Autolysis of Lactococcus lactis is influenced by proteolysis
Buist, G., Venema, G.,Kok, J.
J Bacteriol 1998 ;180(22):5947-5953 1998 |
Characterization of yhcN, a new forespore-specific gene of Bacillus subtilis
Bagyan, I., Noback, M. A., Bron, S., Paidhungat, M.,Setlow, P.
Gene 1998 ;212(2):179-188 1998 |
Cloning, expression, and chromosomal stabilization of the Propionibacterium shermanii proline iminopeptidase gene
(pip) for food-grade application in Lactococcus lactis
Leenhouts, K. J., Bolhuis, A., Boot, J., Deutz, I., Toonen, M. Y., Venema, G., Kok, J.,Ledeboer, A. M.
Appl Environ.Microbiol 1998 ;64(12):4736-4742 1998 |
Clustered organization and transcriptional analysis of a family of five csp genes of Lactococcus lactis MG1363
Wouters, J. A., Sanders, J. W., Kok, J., de Vos, W. M., Kuipers, O. P.,Abee, T.
Microbiology 1998 ;144(0):2885-2893 1998 |
Construction of a food-grade multiple-copy integration system for Lactococcus lactis
Leenhouts, K. J., Bolhuis, A., Venema, G.,Kok, J.
Appl Microbiol Biotechnol 1998 ;49(4):417-423 1998 |
Early steps in the unfolding of thermolysin-like proteases
Vriend, G., Berendsen, H. J., van den Burg, B., Venema, G.,Eijsink, V. G.
J Biol Chem 1998 ;273(52):35074-35077 1998 |
Engineering an enzyme to resist boiling
van den Burg, B., Vriend, G., Veltman, O. R., Venema, G.,Eijsink, V. G.
Proc Natl Acad Sci U S A 1998 ;95(5):2056-2060 1998 |
Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a
eubacterial homolog of archaeal and eukaryotic signal peptidases
Tjalsma, H., Bolhuis, A., van Roosmalen, M. L., Wiegert, T., Schumann, W., Broekhuizen, C. P., Quax, W. J., Venema,
G., Bron, S.,van Dijl, J. M.
Genes Dev. 1998 ;12(15):2318-2331 1998 |
Identification of a sodium chloride-regulated promoter in Lactococcus lactis by single-copy chromosomal fusion
with a reporter gene.
Sanders JW; Venema G; Kok J; Leenhouts K
Mol Gen Genet 1998 ;257(6):681-5 pubmedlink 9604892 1998 |
Probing catalytic hinge bending motions in thermolysin-like proteases by glycine --> alanine mutations.
Veltman OR; Eijsink VG; Vriend G; de Kreij A; Venema G; Van den Burg B
Biochemistry 1998 ;37(15):5305-11 pubmedlink 9548762 1998 |
Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli
Bron, S., Bolhuis, A., Tjalsma, H., Holsappel, S., Venema, G.,van Dijl, J. M.
J Biotechnol 1998 ;64(1):3-13 1998 |
Rendering one autolysis site in Bacillus subtilis neutral protease resistant to cleavage reveals a new
fission.
Van den Burg B; Eijsink VG; Vriend G; Veltman OR; Venema G
Biotechnol Appl Biochem 1998 ;27(0):125-32 pubmedlink 9569607 1998 |
Rolling-circle plasmids from Bacillus subtilis: complete nucleotide sequences and analyses of genes of pTA1015,
pTA1040, pTA1050 and pTA1060, and comparisons with related plasmids from gram-positive bacteria
Meijer, W. J., Wisman, G. B., Terpstra, P., Thorsted, P. B., Thomas, C. M., Holsappel, S., Venema, G.,Bron, S.
FEMS Microbiol Rev. 1998 ;21(4):337-368 1998 |
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins
Bolhuis, A., Broekhuizen, C. P., Sorokin, A., van Roosmalen, M. L., Venema, G., Bron, S., Quax, W. J.,van Dijl, J.
M.
J Biol Chem 1998 ;273(33):21217-21224 1998 |
Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: possible recognition sites for DNA
topoisomerase I
Meima, R., Haan, G. J., Venema, G., Bron, S.,de Jong, S.
Nucleic Acids Res 1998 ;26(10):2366-2373 1998 |
The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several
dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene
Noback, M. A., Holsappel, S., Kiewiet, R., Terpstra, P., Wambutt, R., Wedler, H., Venema, G.,Bron, S.
Microbiology 1998 ;144(0):859-875 1998 |
The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique,
flexible pattern along the DNA helix
Hamoen, L. W., van Werkhoven, A. F., Bijlsma, J. J., Dubnau, D.,Venema, G.
Genes Dev. 1998 ;12(10):1539-1550 1998 |
The Sip(Sli) gene of Streptomyces lividans TK24 specifies an unusual signal peptidase with a putative
C-terminal transmembrane anchor.
Schacht S; Van Mellaert L; Lammertyn E; Tjalsma H; van Dijl JM; Bron S; Anne J
DNA Seq 1998 ;9(2):79-88 pubmedlink 10520736 1998 |
The S-layer gene of Lactobacillus helveticus CNRZ 892: cloning, sequence and heterologous expression
Callegari, M. L., Riboli, B., Sanders, J. W., Cocconcelli, P. S., Kok, J., Venema, G.,Morelli, L.
Microbiology 1998 ;144(0):719-726 1998 |
Use of a genetically enhanced, pediocin-producing starter culture, lactococcus lactis subsp. lactis MM217, To
control listeria monocytogenes in cheddar cheese
Buyong, N., Kok, J.,Luchansky, J. B.
Appl Environ.Microbiol 1998 ;64(12):4842-4845 1998 |
Oligopepidase O
Mierau,I and Kok.J
The Handbook of Proteolytic Enzymes. (Academic Press) 1998 ;0(0):1091-1093 - 1998 |
Qulatitative analysis of gene networks.
Thieffry, D.;Thomas, R.
Pacific Symp. Biocomp. 1998 ;3(-1):77-88 1998 |
A chloride-inducible gene expression cassette and its use in induced lysis of Lactococcus lactis
Sanders, J. W., Venema, G.,Kok, J.
Appl Environ.Microbiol 1997 ;63(12):4877-4882 1997 |
A conserved helicase motif of the AddA subunit of the Bacillus subtilis ATP-dependent nuclease (AddAB) is essential
for DNA repair and recombination
Kooistra, J., Haijema, B. J., Hesseling-Meinders, A.,Venema, G.
Mol Microbiol 1997 ;23(1):137-149 1997 |
Autolysis of Lactococcus lactis caused by induced overproduction of its major autolysin, AcmA
Buist, G., Karsens, H., Nauta, A., van Sinderen, D., Venema, G.,Kok, J.
Appl Environ.Microbiol 1997 ;63(7):2722-2728 1997 |
Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities.
Constitutive and temporally controlled expression of different sip genes
Tjalsma, H., Noback, M. A., Bron, S., Venema, G., Yamane, K.,van Dijl, J. M.
J Biol Chem 1997 ;272(41):25983-25992 1997 |
Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the
activity of ComK, the competence transcription factor of Bacillus subtilis
Turgay, K., Hamoen, L. W., Venema, G.,Dubnau, D.
Genes Dev. 1997 ;11(1):119-128 1997 |
Casein and peptide degradation in lactic acid bacteria
Mierau, I., Kunji, E. R., Venema, G.,Kok, J.
Biotechnol Genet Eng.Rev. 1997 ;14(0):279-301 1997 |
Cloning and analysis of the pepV dipeptidase gene of Lactococcus lactis MG1363
Hellendoorn, M. A., Franke-Fayard, B. M., Mierau, I., Venema, G.,Kok, J.
J Bacteriol 1997 ;179(11):3410-3415 1997 |
Design of thermolabile bacteriophage repressor mutants by comparative molecular modeling
Nauta, A., van den Burg, B., Karsens, H., Venema, G.,Kok, J.
Nat Biotechnol 1997 ;15(10):980-983 1997 |
Engineering thermolysin-like proteases whose stability is largely independent of calcium
Veltman, O. R., Vriend, G., van den Burg, B., Hardy, F., Venema, G.,Eijsink, V. G.
FEBS Lett. 1997 ;405(2):241-244 1997 |
Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond
Mansfeld, J., Vriend, G., Dijkstra, B. W., Veltman, O. R., van den Burg, B., Venema, G., Ulbrich-Hofmann,
R.,Eijsink, V. G.
J Biol Chem 1997 ;272(17):11152-11156 1997 |
Model building of a thermolysin-like protease by mutagenesis
Frigerio, F., Margarit, I., Nogarotto, R., Grandi, G., Vriend, G., Hardy, F., Veltman, O. R., Venema, G.,Eijsink,
V. G.
Protein Eng. 1997 ;10(3):223-230 1997 |
Mutational analysis of a surface area that is critical for the thermal stability of thermolysin-like proteases
Veltman, O. R., Vriend, G., Hardy, F., Mansfeld, J., van den Burg, B., Venema, G.,Eijsink, V. G.
Eur.J Biochem 1997 ;248(2):433-440 1997 |
Role of enzymes of homologous recombination in illegitimate plasmid recombination in Bacillus subtilis
Meima, R., Haijema, B. J., Dijkstra, H., Haan, G. J., Venema, G.,Bron, S.
J Bacteriol 1997 ;179(4):1219-1229 1997 |
Substrate specificity of hybrid modules from peptide synthetases
Elsner, A., Engert, H., Saenger, W., Hamoen, L. W., Venema, G.,Bernhard, F.
J Biol Chem 1997 ;272(8):4814-4819 1997 |
The chemistry and enzymology of the type I signal peptidases
Dalbey, R. E., Lively, M. O., Bron, S.,van Dijl, J. M.
Protein Sci 1997 ;6(6):1129-1138 1997 |
The complete genome sequence of the gram-positive bacterium Bacillus subtilis
Kunst, F., Ogasawara, N., Moszer, I., Bron,S., Noback,M., Holsappel,S., etal
Nature 1997 ;390(6657):249-256 1997 |
The signal peptidase II (Isp) gene of Bacillus subtilis
Pragai, Z., Tjalsma, H., Bolhuis, A., van Dijl, J. M., Venema, G.,Bron, S.
Microbiology 1997 ;143(0):1327-1333 1997 |
A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome
Noback, M. A., Terpstra, P., Holsappel, S., Venema, G.,Bron, S.
Microbiology 1996 ;142(0):3021-3026 1996 |
A general system for generating unlabelled gene replacements in bacterial chromosomes
Leenhouts, K. J., Buist, G., Bolhuis, A., ten Berge, A. M., Kiel, J. A., Mierau, I., Dabrowska, M., Venema, G.,Kok,
J.
Mol Gen.Genet 1996 ;253(1):217-224 1996 |
A positive selection vector for the analysis of structural plasmid instability in Bacillus subtilis
Meima, R., Venema, G.,Bron, S.
Plasmid 1996 ;35(1):14-30 1996 |
Analysis of structural determinants of the stability of thermolysin-like proteases by molecular modelling and
site-directed mutagenesis
Veltman, O. R., Vriend, G., Middelhoven, P. J., van den Burg, B., Venema, G.,Eijsink, V. G.
Protein Eng. 1996 ;9(12):1181-1189 1996 |
Bacillus subtilis can modulate its capacity and specificity for protein secretion through temporally controlled
expression of the sipS gene for signal peptidase I
Bolhuis, A., Sorokin, A., Azevedo, V., Ehrlich, S. D., Braun, P. G., de Jong, A., Venema, G., Bron, S.,van Dijl, J.
M.
Mol Microbiol 1996 ;22(4):605-618 1996 |
Cloning of heterologous genes specifying detrimental proteins on pUC-derived plasmids in Escherichia coli
M?ller, J. P., van Dijl, J. M., Venema, G.,Bron, S.
Mol Gen.Genet 1996 ;252(1):207-211 1996 |
Effects of lysine-to-glycine mutations in the ATP-binding consensus sequences in the AddA and AddB subunits on the
Bacillus subtilis AddAB enzyme activities
Haijema, B. J., Meima, R., Kooistra, J.,Venema, G.
J Bacteriol 1996 ;178(17):5130-5137 1996 |
Fate of peptides in peptidase mutants of Lactococcus lactis
Kunji, E. R., Mierau, I., Poolman, B., Konings, W. N., Venema, G.,Kok, J.
Mol Microbiol 1996 ;21(1):123-131 1996 |
Identification and characterization of a novel type of replication terminator with bidirectional activity on the
Bacillus subtilis theta plasmid pLS20
Meijer, W. J., Smith, M., Wake, R. G., de Boer, A. L., Venema, G.,Bron, S.
Mol Microbiol 1996 ;19(6):1295-1306 1996 |
Inducible gene expression and environmentally regulated genes in lactic acid bacteria
Kok, J.
Antonie Van Leeuwenhoek 1996 ;70(2):129-145 1996 |
Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage
r1t
Nauta, A., van Sinderen, D., Karsens, H., Smit, E., Venema, G.,Kok, J.
Mol Microbiol 1996 ;19(6):1331-1341 1996 |
Molecular analysis of the replication origin of the Lactococcus lactis plasmid pCJ305
Foley, S., Bron, S., Venema, G., Daly, C.,Fitzgerald, G. F.
Plasmid 1996 ;36(2):125-141 1996 |
Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1
van Veen, H. W., Venema, K., Bolhuis, H., Oussenko, I., Kok, J., Poolman, B., Driessen, A. J.,Konings, W. N.
Proc Natl Acad Sci U S A 1996 ;93(20):10668-10672 1996 |
Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk
Mierau, I., Kunji, E. R., Leenhouts, K. J., Hellendoorn, M. A., Haandrikman, A. J., Poolman, B., Konings, W. N.,
Venema, G.,Kok, J.
J Bacteriol 1996 ;178(10):2794-2803 1996 |
Mutational analysis and chemical modification of Cys24 of lactococcin B, a bacteriocin produced by Lactococcus
lactis
Venema, K., Dost, M. H., Venema, G.,Kok, J.
Microbiology 1996 ;142(0):2825-2830 1996 |
Regulated expression of the dinR and recA genes during competence development and SOS induction in Bacillus
subtilis
Haijema, B. J., van Sinderen, D., Winterling, K., Kooistra, J., Venema, G.,Hamoen, L. W.
Mol Microbiol 1996 ;22(1):75-85 1996 |
Replacement of the lysine residue in the consensus ATP-binding sequence of the AddA subunit of AddAB drastically
affects chromosomal recombination in transformation and transduction of Bacillus subtilis
Haijema, B. J., Noback, M. A., Hesseling, A., Kooistra, J., Venema, G.,Meima, R.
Mol Microbiol 1996 ;21(5):989-999 1996 |
Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage r1t
van Sinderen, D., Karsens, H., Kok, J., Terpstra, P., Ruiters, M. H., Venema, G.,Nauta, A.
Mol Microbiol 1996 ;19(6):1343-1355 1996 |
The C terminus of the AddA subunit of the Bacillus subtilis ATP-dependent DNase is required for the ATP-dependent
exonuclease activity but not for the helicase activity
Haijema, B. J., Venema, G.,Kooistra, J.
J Bacteriol 1996 ;178(17):5086-5091 1996 |
The expression of a plasmid-specified exported protein causes structural plasmid instability in Bacillus subtilis
Cordes, C., Meima, R., Twiest, B., Kazemier, B., Venema, G., van Dijl, J. M.,Bron, S.
J Bacteriol 1996 ;178(17):5235-5242 1996 |
The genes for secretion and maturation of lactococcins are located on the chromosome of Lactococcus lactis IL1403
Venema, K., Dost, M. H., Beun, P. A., Haandrikman, A. J., Venema, G.,Kok, J.
Appl Environ.Microbiol 1996 ;62(5):1689-1692 1996 |
The proteolytic systems of lacatic acid bacteria
Kunji, E.R., Mierau, I., Hagting, A., Poolman, B., Konings, W.N.
Antonie van Leeuwenhoek 1996 ;70(0):187-221 1996 |
Topology of LcnD, a protein implicated in the transport of bacteriocins from Lactococcus lactis
Franke, C. M., Leenhouts, K. J., Haandrikman, A. J., Kok, J., Venema, G.,Venema, K.
J Bacteriol 1996 ;178(6):1766-1769 1996 |
A general method for the consecutive integration of single copies of a heterologous gene at multiple locations in
the Bacillus subtilis chromosome by replacement recombination
Kiel, J. A., ten Berge, A. M., Borger, P.,Venema, G.
Appl Environ.Microbiol 1995 ;61(12):4244-4250 1995 |
A small gene, designated comS, located within the coding region of the fourth amino acid-activation domain of srfA,
is required for competence development in Bacillus subtilis
Hamoen, L. W., Eshuis, H., Jongbloed, J. D., Venema, G.,van Sinderen, D.
Mol Microbiol 1995 ;15(1):55-63 1995 |
A system to generate chromosomal mutations in Lactococcus lactis which allows fast analysis of targeted genes
Law, J., Buist, G., Haandrikman, A. J., Kok, J., Venema, G.,Leenhouts, K. J.
J Bacteriol 1995 ;177(24):7011-7018 1995 |
Analysis of lactococcin secretion and immunity in Lactococcus lactis
Kok, J., Venema, K.,Venema, G.
Dev.Biol Stand. 1995 ;85(0):653-659 1995 |
Characterization of single strand origins of cryptic rolling-circle plasmids from Bacillus subtilis
Meijer, W. J., Venema, G.,Bron, S.
Nucleic Acids Res 1995 ;23(4):612-619 1995 |
Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon
Meijer, W. J., de Boer, A. J., van Tongeren, S., Venema, G.,Bron, S.
Nucleic Acids Res 1995 ;23(16):3214-3223 1995 |
Chitinase B from Serratia marcescens BJL200 is exported to the periplasm without processing
Brurberg, M. B., Eijsink, V. G., Haandrikman, A. J., Venema, G.,Nes, I. F.
Microbiology 1995 ;141(0):123-131 1995 |
Cloning and molecular analysis of the dihydrofolate reductase gene from Lactococcus lactis
Leszczynska, K., Bolhuis, A., Leenhouts, K. J., Venema, G.,Ceglowski, P.
Appl Environ.Microbiol 1995 ;61(2):561-566 1995 |
comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus
subtilis
van Sinderen, D., Luttinger, A., Kong, L., Dubnau, D., Venema, G.,Hamoen, L. W.
Mol Microbiol 1995 ;15(3):455-462 1995 |
Differential expression of two closely related deoxyribonuclease genes, nucA and nucB, in Bacillus subtilis
van Sinderen, D., Kiewiet, R.,Venema, G.
Mol Microbiol 1995 ;15(2):213-223 1995 |
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in different
Bacillus subtilis strains
Meijer, W. J., van der Lelie, D., Venema, G.,Bron, S.
Plasmid 1995 ;33(2):79-89 1995 |
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in
Lactococcus lactis
Meijer, W. J., van der Lelie, D., Venema, G.,Bron, S.
Plasmid 1995 ;33(2):91-99 1995 |
Expression of lactococcin A and pediocin PA-1 in heterologous hosts
Chikindas, M. L., Venema, K., Ledeboer, A. M., Venema, G.,Kok, J.
Lett.Appl Microbiol 1995 ;21(3):183-189 1995 |
Expression of the ATP-dependent deoxyribonuclease of Bacillus subtilis is under competence-mediated control
Haijema, B. J., Hamoen, L. W., Kooistra, J., Venema, G.,van Sinderen, D.
Mol Microbiol 1995 ;15(2):203-211 1995 |
Functional analysis of the pediocin operon of Pediococcus acidilactici PAC1.0: PedB is the immunity protein and
PedD is the precursor processing enzyme
Venema, K., Kok, J., Marugg, J. D., Toonen, M. Y., Ledeboer, A. M., Venema, G.,Chikindas, M. L.
Mol Microbiol 1995 ;17(3):515-522 1995 |
Generation of the glycyl radical of the anaerobic Escherichia coli ribonucleotide reductase requires a specific
activating enzyme.
Sun, X.., Eliasson, R., Pontis, E., Andersson, J., Buist, G., Sjoberg, B.M., Reichard, P.
J Biol Chem 1995 ;270(0):2443-2446 1995 |
Genetic modification and the proteolytic system of lactococci
Venema, G., Haandrikman, A. J.,Kok, J.
Dev.Biol Stand. 1995 ;85(0):495-502 1995 |
Genetics of peptide degradation in Lactococcus: gene cloning, construction and analysis of peptidase negative
mutants
Mierau, I., Haandrikman, A. J., Leenhouts, K. J., Tan, P. S., Konings, W. N., Venema, G.,Kok, J.
Dev.Biol Stand. 1995 ;85(0):503-507 1995 |
Identification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and
functional similarities with LexA-like proteases
van Dijl, J. M., de Jong, A., Venema, G.,Bron, S.
J Biol Chem 1995 ;270(8):3611-3618 1995 |
Lactococcal bacteriocins: mode of action and immunity
Venema, K., Venema, G.,Kok, J.
Trends Microbiol 1995 ;3(8):299-304 1995 |
Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus
lactis, a muramidase needed for cell separation
Buist, G., Kok, J., Leenhouts, K. J., Dabrowska, M., Venema, G.,Haandrikman, A. J.
J Bacteriol 1995 ;177(6):1554-1563 1995 |
Overproduction of the ATP-dependent nuclease AddAB improves the structural stability of a model plasmid system in
Bacillus subtilis
Meima, R., Haijema, B. J., Venema, G.,Bron, S.
Mol Gen.Genet 1995 ;248(4):391-398 1995 |
Stress response in Lactococcus lactis: cloning, expression analysis, and mutation of the lactococcal superoxide
dismutase gene
Sanders, J. W., Leenhouts, K. J., Haandrikman, A. J., Venema, G.,Kok, J.
J Bacteriol 1995 ;177(18):5254-5260 1995 |
Structural and functional analysis of the single-strand origin of replication from the lactococcal plasmid pWV01
Seegers, J. F., Zhao, A. C., Meijer, W. J., Khan, S. A., Venema, G.,Bron, S.
Mol Gen.Genet 1995 ;249(1):43-50 1995 |
Structural determinants of the stability of thermolysin-like proteinases
Eijsink, V. G., Veltman, O. R., Aukema, W., Vriend, G.,Venema, G.
Nat Struct.Biol 1995 ;2(5):374-379 1995 |
The endogenous Bacillus subtilis (natto) plasmids pTA1015 and pTA1040 contain signal peptidase-encoding genes:
identification of a new structural module on cryptic plasmids
Meijer, W. J., de Jong, A., Wisman, G. B., Tjalsma, H., Venema, G., Bron, S.,van Dijl, J. M.
Mol Microbiol 1995 ;17(4):621-631 1995 |
Use of continuous culture for the selection of plasmids with improved segregational stability
Seegers, J. F., Franke, C. M., Kiewiet, R., Venema, G.,Bron, S.
Plasmid 1995 ;33(1):71-77 1995 |
comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis
van Sinderen, D., Venema, G.
J Bacteriol 1994 ;176(18):5762-5770 1994 |
Design, synthesis, and preliminary characterization of tyrosine-containing polyarylates: new biomaterials for
medical applications
Fiordeliso, J., Bron, S.,Kohn, J.
J Biomater.Sci Polym.Ed. 1994 ;5(6):497-510 1994 |
Expression of a chitinase gene from Serratia marcescens in Lactococcus lactis and Lactobacillus plantarum
Brurberg, M. B., Haandrikman, A. J., Leenhouts, K. J., Venema, G.,Nes, I. F.
Appl Microbiol Biotechnol 1994 ;42(1):108-115 1994 |
Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen
biosynthesis and degradation
Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G.
Mol Microbiol 1994 ;11(1):203-218 1994 |
Identification of TlpC, a novel 62 kDa MCP-like protein from Bacillus subtilis
Hanlon, D. W., Rosario, M. M., Ordal, G. W., Venema, G.,van Sinderen, D.
Microbiology 1994 ;140(0):1847-1854 1994 |
Mode of action of LciA, the lactococcin A immunity protein
Venema, K., Haverkort, R. E., Abee, T., Haandrikman, A. J., Leenhouts, K. J., de Leij, L., Venema, G.,Kok, J.
Mol Microbiol 1994 ;14(3):521-532 1994 |
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis
van Sinderen, D., ten Berge, A. M., Hayema, B. J., Hamoen, L. W.,Venema, G.
Mol Microbiol 1994 ;11(4):695-703 1994 |
Protein stabilization by hydrophobic interactions at the surface
van den Burg, B., Dijkstra, B. W., Vriend, G., van der Vossen, J. M. B. M., Venema, G.,Eijsink, V. G.
Eur.J Biochem 1994 ;220(3):981-985 1994 |
The effect of engineering surface loops on the thermal stability of Bacillus subtilis neutral protease
Hardy, F., Vriend, G., van der Vossen, J. M. B. M., Frigerio, F., Grandi, G., Venema, G.,Eijsink, V. G.
Protein Eng. 1994 ;7(3):425-430 1994 |
The majority of lactococcal plasmids carry a highly related replicon
Seegers, J. F., Bron, S., Franke, C. M., Venema, G.,Kiewiet, R.
Microbiology 1994 ;140(0):1291-1300 1994 |
Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and
construction of a chromosomal deletion mutant
Mierau, I., Haandrikman, A. J., Velterop, O., Tan, P. S., Leenhouts, K. J., Konings, W. N., Venema, G.,Kok, J.
J Bacteriol 1994 ;176(10):2854-2861 1994 |
Characterization of the srfA locus of Bacillus subtilis: only the valine-activating domain of srfA is involved in
the establishment of genetic competence
van Sinderen, D., Galli, G., Cosmina, P., de Ferra, F., Withoff, S., Venema, G.,Grandi, G.
Mol Microbiol 1993 ;8(5):833-841 1993 |
Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian
enkephalinase
Mierau, I., Tan, P. S., Haandrikman, A. J., Mayo, B., Kok, J., Leenhouts, K. J., Konings, W. N.,Venema, G.
J Bacteriol 1993 ;175(7):2087-2096 1993 |
Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis
Tynkkynen, S., Buist, G., Kunji, E. R., Kok, J., Poolman, B., Venema, G.,Haandrikman, A. J.
J Bacteriol 1993 ;175(23):7523-7532 1993 |
In vitro assay for the Bacillus subtilis signal peptidase SipS: systems for efficient in vitro
transcription-translation and processing of precursors of secreted proteins
Vehmaanpera, J., Gorner, A., Venema, G., Bron, S.,van Dijl, J. M.
FEMS Microbiol Lett. 1993 ;114(2):207-214 1993 |
Introduction of disulfide bonds into Bacillus subtilis neutral protease
van den Burg, B., Dijkstra, B. W., van der Vossen, J. M. B. M., Stulp, B. K., Eijsink, V. G.,Venema, G.
Protein Eng. 1993 ;6(5):521-527 1993 |
Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic
membrane of target cells
Chikindas, M. L., Garcia-Garcera, M. J., Driessen, A. J., Ledeboer, A. M., Nissen-Meyer, J., Nes, I. F., Abee, T.,
Konings, W. N.,Venema, G.
Appl Environ.Microbiol 1993 ;59(11):3577-3584 1993 |
Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis
Cosmina, P., Rodriguez, F., de Ferra, F., Grandi, G., Perego, M., Venema, G.,van Sinderen, D.
Mol Microbiol 1993 ;8(5):821-831 1993 |
Stabilization of Bacillus stearothermophilus neutral protease by introduction of prolines
Hardy, F., Vriend, G., Veltman, O. R., van der Vossen, J. M. B. M., Venema, G.,Eijsink, V. G.
FEBS Lett. 1993 ;317(1):89-92 1993 |
The Bacillus subtilis addAB genes are fully functional in Escherichia coli
Kooistra, J., Haijema, B. J.,Venema, G.
Mol Microbiol 1993 ;7(6):915-923 1993 |
Theta replication of the lactococcal plasmid pWVO2
Kiewiet, R., Bron, S., de Jonge, K., Venema, G.,Seegers, J. F.
Mol Microbiol 1993 ;10(2):319-327 1993 |
Two putative insertion sequences flank a truncated glycogen branching enzyme gene in the thermophile Bacillus
stearothermophilus CU21
Kiel, J. A., Boels, J. M., ten Berge, A. M.,Venema, G.
DNA Seq. 1993 ;4(1):1-9 1993 |
Protein Secretion in Bacillus subtilis. In; DNA transfer and gene expression in microorganisms
van Dijl,J.M.; de Jong, A; Smith,H; Venema, G.; Bron, S.
1993 ;0(0):0-0 - 1993 |
The mode of replication is a major factor in segregational plasmid instability in Lactococcus lactis
Kiewiet,R.;Kok,J.;Seegers,J.F.M.L.;Venema, G.;Bron,S.
Appl. Environmen. Microbiol. 1993 ;59(2):358-364 1993 |
Characterization of transcription initiation and termination signals of the proteinase genes of Lactococcus lactis
Wg2 and enhancement of proteolysis in L. lactis
van der Vossen, J. M. B. M., Kodde, J., Haandrikman, A. J., Venema, G.,Kok, J.
Appl Environ.Microbiol 1992 ;58(9):3142-3149 1992 |
Cloning, sequencing, and expression in Escherichia coli of lcnB, a third bacteriocin determinant from the
lactococcal bacteriocin plasmid p9B4-6
van Belkum, M. J., Kok, J.,Venema, G.
Appl Environ.Microbiol 1992 ;58(2):572-577 1992 |
Effects of changing the interaction between subdomains on the thermostability of Bacillus neutral proteases
Eijsink, V. G., Vriend, G., van der Vossen, J. M. B. M., Hazes, B., van den Burg, B.,Venema, G.
Proteins 1992 ;14(2):224-236 1992 |
Gene expression in Lactococcus lactis
van de Guchte, M., Kok, J.,Venema, G.
FEMS Microbiol Rev. 1992 ;8(2):73-92 1992 |
Increasing the thermostability of a neutral protease by replacing positively charged amino acids in the N-terminal
turn of alpha-helices
Eijsink, V. G., Vriend, G., van den Burg, B., van der Zee, J. R.,Venema, G.
Protein Eng. 1992 ;5(2):165-170 1992 |
Increasing the thermostability of the neutral proteinase of Bacillus stearothermophilus by improvement of internal
hydrogen-bonding
Eijsink, V. G., Vriend, G., van der Zee, J. R., van den Burg, B.,Venema, G.
Biochem J 1992 ;285(0):625-628 1992 |
Introduction of a stabilizing 10 residue beta-hairpin in Bacillus subtilis neutral protease
Eijsink, V. G., Vriend, G., van den Burg, B., van der Zee, J. R., Veltman, O. R., Stulp, B. K.,Venema, G.
Protein Eng. 1992 ;5(2):157-163 1992 |
Localization and accessibility of antigenic sites of the extracellular serine proteinase of Lactococcus lactis
Laan, H., Kok, J., Haandrikman, A. J., Venema, G.,Konings, W. N.
Eur.J Biochem 1992 ;204(2):815-820 1992 |
Lysozyme expression in Lactococcus lactis
van de Guchte, M., van der Wal, F. J., Kok, J.,Venema, G.
Appl Microbiol Biotechnol 1992 ;37(2):216-224 1992 |
Molecular analyses of the lactococcin A gene cluster from Lactococcus lactis subsp. lactis biovar diacetylactis WM4
Stoddard, G. W., Petzel, J. P., van Belkum, M. J., Kok, J.,McKay, L. L.
Appl Environ.Microbiol 1992 ;58(6):1952-1961 1992 |
Nucleotide sequence of the Synechococcus sp. PCC7942 hemE gene encoding the homologue of mammalian uroporphyrinogen
decarboxylase
Kiel, J. A., ten Berge, A. M.,Venema, G.
DNA Seq. 1992 ;2(6):415-418 1992 |
Plasmid maintenance in Bacillus stearothermophilus is strain-dependent
Oskam, L., Venema, G.,Bron, S.
FEMS Microbiol Lett. 1992 ;72(3):203-208 1992 |
Plasmid pTB913 derivatives are segregationally stable in Bacillus subtilis at elevated temperatures
Oskam, L., Venema, G.,Bron, S.
Plasmid 1992 ;28(1):70-79 1992 |
Protein export elements from Lactococcus lactis
Perez-Martinez, G., Kok, J., Venema, G., van Dijl, J. M., Smith, H.,Bron, S.
Mol Gen.Genet 1992 ;234(3):401-411 1992 |
Signal peptidase I of Bacillus subtilis: patterns of conserved amino acids in prokaryotic and eukaryotic type I
signal peptidases
van Dijl, J. M., de Jong, A., Vehmaanpera, J., Venema, G.,Bron, S.
EMBO J 1992 ;11(8):2819-2828 1992 |
The effect of cavity-filling mutations on the thermostability of Bacillus stearothermophilus neutral protease
Eijsink, V. G., Dijkstra, B. W., Vriend, G., van der Zee, J. R., Veltman, O. R., van der Vossen, J. M. B. M., van
den Burg, B., Kempe, S.,Venema, G.
Protein Eng. 1992 ;5(5):421-426 1992 |
The glgB gene from the thermophile Bacillus caldolyticus encodes a thermolabile branching enzyme
Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G.
DNA Seq. 1992 ;3(4):221-232 1992 |
The integrated state of the rolling-circle plasmid pTB913 in the composite Bacillus plasmid pTB19
Oskam, L., Hillenga, D. J., Venema, G.,Bron, S.
Mol Gen.Genet 1992 ;233(3):462-468 1992 |
A highly thermostable neutral protease from Bacillus caldolyticus: cloning and expression of the gene in Bacillus
subtilis and characterization of the gene product
van den Burg, B., Enequist, H. G., van der Haar, M. E., Eijsink, V. G., Stulp, B. K.,Venema, G.
J Bacteriol 1991 ;173(13):4107-4115 1991 |
A possible contribution of mRNA secondary structure to translation initiation efficiency in Lactococcus lactis
van de Guchte, M., van der Lende, T., Kok, J.,Venema, G.
FEMS Microbiol Lett. 1991 ;65(2):201-208 1991 |
Chromosomal stabilization of the proteinase genes in Lactococcus lactis
Leenhouts, K. J., Gietema, J., Kok, J.,Venema, G.
Appl Environ.Microbiol 1991 ;57(9):2568-2575 1991 |
Cloning, sequencing, and expression of Bacillus subtilis genes involved in ATP-dependent nuclease synthesis
Kooistra, J., Venema, G.
J Bacteriol 1991 ;173(12):3644-3655 1991 |
Distance-dependent translational coupling and interference in Lactococcus lactis
van de Guchte, M., Kok, J.,Venema, G.
Mol Gen.Genet 1991 ;227(1):65-71 1991 |
Engineering of the Lactococcus lactis serine proteinase by construction of hybrid enzymes
Vos, P., Boerrigter, I. J., Buist, G., Haandrikman, A. J., Nijhuis, M., de Reuver, M. B., Siezen, R. J., Venema,
G., de Vos, W. M.,Kok, J.
Protein Eng. 1991 ;4(4):479-484 1991 |
High performance affinity chromatography of Bacillus neutral proteases
Eijsink, V. G., van den Burg, B.,Venema, G.
Biotechnol Appl Biochem 1991 ;14(3):275-283 1991 |
Identification of a new genetic determinant for cell aggregation associated with lactose plasmid transfer in
Lactococcus lactis
van der Lelie, D., Chavarri, F., Venema, G.,Gasson, M. J.
Appl Environ.Microbiol 1991 ;57(1):201-206 1991 |
Improving the thermostability of the neutral protease of Bacillus stearothermophilus by replacing a buried
asparagine by leucine
Eijsink, V. G., van der Zee, J. R., van den Burg, B., Vriend, G.,Venema, G.
FEBS Lett. 1991 ;282(1):13-16 1991 |
Isolation, sequence and expression in Escherichia coli, Bacillus subtilis and Lactococcus lactis of the DNase
(streptodornase)-encoding gene from Streptococcus equisimilis H46A
Wolinowska, R., Ceglowski, P., Kok, J.,Venema, G.
Gene 1991 ;106(1):115-119 1991 |
Lack of specific hybridization between the lep genes of Salmonella typhimurium and Bacillus licheniformis
van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G.
FEMS Microbiol Lett. 1991 ;65(3):345-351 1991 |
Lactococcal plasmid pWV01 as an integration vector for lactococci
Leenhouts, K. J., Kok, J.,Venema, G.
Appl Environ.Microbiol 1991 ;57(9):2562-2567 1991 |
Lactococcal proteinase maturation protein PrtM is a lipoprotein
Haandrikman, A. J., Kok, J.,Venema, G.
J Bacteriol 1991 ;173(14):4517-4525 1991 |
Molecular cloning and nucleotide sequence of the glycogen branching enzyme gene (glgB) from Bacillus
stearothermophilus and expression in Escherichia coli and Bacillus subtilis
Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G.
Mol Gen.Genet 1991 ;230(1):136-144 1991 |
Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis
subsp. cremoris
Mayo, B., Kok, J., Venema, K., Bockelmann, W., Teuber, M., Reinke, H.,Venema, G.
Appl Environ.Microbiol 1991 ;57(1):38-44 1991 |
Non-functional expression of Escherichia coli signal peptidase I in Bacillus subtilis
van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G.
J Gen.Microbiol 1991 ;137(0):2073-2083 1991 |
Nucleotide sequence and characterization of the broad-host-range lactococcal plasmid pWVO1
Leenhouts, K. J., Tolner, B., Bron, S., Kok, J., Venema, G.,Seegers, J. F.
Plasmid 1991 ;26(1):55-66 1991 |
Organization and nucleotide sequences of two lactococcal bacteriocin operons
van Belkum, M. J., Hayema, B. J., Jeeninga, R. E., Kok, J.,Venema, G.
Appl Environ.Microbiol 1991 ;57(2):492-498 1991 |
Plasmid deletion formation between short direct repeats in Bacillus subtilis is stimulated by single-stranded
rolling-circle replication intermediates
Bron, S., Holsappel, S., Venema, G.,Peeters, B. P.
Mol Gen.Genet 1991 ;226(1):88-96 1991 |
Plasmid instability and molecular cloning in Bacillus subtilis
Bron, S., Meijer, W., Holsappel, S.,Haima, P.
Res Microbiol 1991 ;142(7):875-883 1991 |
Processing of the lactococcal extracellular serine proteinase
Haandrikman, A. J., Meesters, R., Laan, H., Konings, W. N., Kok, J.,Venema, G.
Appl Environ.Microbiol 1991 ;57(7):1899-1904 1991 |
Proteinase genes of cheese starter cultures
Kok, J.
Biochem Soc.Trans. 1991 ;19(3):670-674 1991 |
Replacement recombination in Lactococcus lactis
Leenhouts, K. J., Kok, J.,Venema, G.
J Bacteriol 1991 ;173(15):4794-4798 1991 |
Signal peptidase I overproduction results in increased efficiencies of export and maturation of hybrid secretory
proteins in Escherichia coli
van Dijl, J. M., de Jong, A., Smith, H., Bron, S.,Venema, G.
Mol Gen.Genet 1991 ;227(1):40-48 1991 |
Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule
Vriend, G., Berendsen, H. J., van der Zee, J. R., van den Burg, B., Venema, G.,Eijsink, V. G.
Protein Eng. 1991 ;4(8):941-945 1991 |
The bacteriocin lactococcin A specifically increases permeability of lactococcal cytoplasmic membranes in a
voltage-independent, protein-mediated manner
van Belkum, M. J., Kok, J., Venema, G., Holo, H., Nes, I. F., Konings, W. N.,Abee, T.
J Bacteriol 1991 ;173(24):7934-7941 1991 |
The large Bacillus plasmid pTB19 contains two integrated rolling-circle plasmids carrying mobilization functions
Oskam, L., Hillenga, D. J., Venema, G.,Bron, S.
Plasmid 1991 ;26(1):30-39 1991 |
Thermostability of Bacillus subtilis neutral protease
Eijsink, V. G., van den Burg, B., Vriend, G., Berendsen, H. J.,Venema, G.
Biochem Int. 1991 ;24(3):517-525 1991 |
An improved beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis
Haima, P., van Sinderen, D., Bron, S.,Venema, G.
Gene 1990 ;93(1):41-47 1990 |
Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences
Peeters, B. P., Bron, S.,Ehrlich, S. D.
EMBO J 1990 ;9(0):3023-9 1990 |
Conjugal mobilization of streptococcal plasmid pMV158 between strains of Lactococcus lactis subsp. lactis
van der Lelie, D., Wosten, H. A., Bron, S., Oskam, L.,Venema, G.
J Bacteriol 1990 ;172(1):47-52 1990 |
Contribution of the C-terminal amino acid to the stability of Bacillus subtilis neutral protease
Eijsink, V. G., Vriend, G., van den Burg, B., Venema, G.,Stulp, B. K.
Protein Eng. 1990 ;4(1):99-104 1990 |
Genetics of the proteolytic system of lactic acid bacteria
Kok, J.
FEMS Microbiol Rev. 1990 ;7(1):15-42 1990 |
Heterologous gene expression in Lactococcus lactis subsp. lactis: synthesis, secretion, and processing of the
Bacillus subtilis neutral protease
van de Guchte, M., Kodde, J., van der Vossen, J. M. B. M., Kok, J.,Venema, G.
Appl Environ.Microbiol 1990 ;56(9):2606-2611 1990 |
Identification of autodigestion target sites in Bacillus subtilis neutral proteinase
van den Burg, B., Eijsink, V. G., Stulp, B. K.,Venema, G.
Biochem J 1990 ;272(1):93-97 1990 |
Insertion elements on lactococcal proteinase plasmids
Haandrikman, A. J., van Leeuwen, C., Kok, J., Vos, P., de Vos, W. M.,Venema, G.
Appl Environ.Microbiol 1990 ;56(6):1890-1896 1990 |
Isolation and characterization of comL, a transcription unit involved in competence development of Bacillus
subtilis
van Sinderen, D., Withoff, S., Boels, H.,Venema, G.
Mol Gen.Genet 1990 ;224(3):396-404 1990 |
Molecular cloning of the Salmonella typhimurium lep gene in Escherichia coli
van Dijl, J. M., van den Bergh, R., Reversma, T., Smith, H., Bron, S.,Venema, G.
Mol Gen.Genet 1990 ;223(2):233-240 1990 |
Novel plasmid marker rescue transformation system for molecular cloning in Bacillus subtilis enabling direct
selection of recombinants
Haima, P., Bron, S.,Venema, G.
Mol Gen.Genet 1990 ;223(2):185-191 1990 |
Nucleotide sequence of the Synechococcus sp. PCC7942 branching enzyme gene (glgB): expression in Bacillus subtilis
Kiel, J. A., Boels, J. M., Beldman, G.,Venema, G.
Gene 1990 ;89(1):77-84 1990 |
Translational coupling in a penP-lacZ gene fusion in Bacillus subtilis and Escherichia coli: use of AUA as a
restart codon
Peijnenburg, A. A. C. M., Venema, G.,Bron, S.
Mol Gen.Genet 1990 ;221(2):267-272 1990 |
Development of a beta-galactosidase alfa-complementation system for molecular cloning in Bacillus subtilis
Haima, P.; van Sinderen, D.; Schotting, H., Bron, S,;Venema, G.
Gene 1990 ;86(0):63-69 1990 |
Breakage--reunion and copy choice mechanisms of recombination between short homologous sequences
Brunier, D., Peeters, B. P., Bron, S.,Ehrlich, S. D.
EMBO J 1989 ;8(10):3127-3133 1989 |
Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis
Leenhouts, K. J., Kok, J.,Venema, G.
Appl Environ.Microbiol 1989 ;55(2):394-400 1989 |
Cloning and expression of the branching enzyme gene (glgB) from the cyanobacterium Synechococcus sp. PCC7942 in
Escherichia coli
Kiel, J. A., Elgersma, H. S., Beldman, G., Vossen, J. P.,Venema, G.
Gene 1989 ;78(1):9-17 1989 |
Cloning of two bacteriocin genes from a lactococcal bacteriocin plasmid
van Belkum, M. J., Hayema, B. J., Geis, A., Kok, J.,Venema, G.
Appl Environ.Microbiol 1989 ;55(5):1187-1191 1989 |
Construction of a lactococcal expression vector: expression of hen egg white lysozyme in Lactococcus lactis subsp.
lactis
van de Guchte, M., van der Vossen, J. M. B. M., Kok, J.,Venema, G.
Appl Environ.Microbiol 1989 ;55(1):224-228 1989 |
Identification of a gene required for maturation of an extracellular lactococcal serine proteinase
Haandrikman, A. J., Kok, J., Laan, H., Soemitro, S., Ledeboer, A. M., Konings, W. N.,Venema, G.
J Bacteriol 1989 ;171(5):2789-2794 1989 |
One-step affinity purification of Bacillus neutral proteases using bacitracin-silica
van den Burg, B., Eijsink, V. G., Stulp, B. K.,Venema, G.
J Biochem Biophys.Methods 1989 ;18(3):209-219 1989 |
Plasmid deletion formation in recE4 and addB72 mutants of Bacillus subtilis
Peijnenburg, A. A. C. M., Breed, P. V., Bron, S.,Venema, G.
Plasmid 1989 ;21(3):205-215 1989 |
Similarity of minus origins of replication and flanking open reading frames of plasmids pUB110, pTB913 and pMV158
van der Lelie, D., Bron, S., Venema, G.,Oskam, L.
Nucleic Acids Res 1989 ;17(18):7283-7294 1989 |
Recombination in bacterial plasmids and chromosomes
Ehrlich, S.D.;Brunier, D.;Peeters, B.; Bron, S.;Janniere, L.;Michel,B.; Sozhamannan,S.
1989 ;0(0):197-203 - 1989 |
Breakage-reunion and copy choise mechanisms of recombination between short homologous sequences
Brunier, D.;Peeters, B.P.H.;Bron,S.;Ehrlich, S.D.
The EMBO Journal 1989 ;8(10):3127-3133 1989 |
Characterization of signal-sequence-coding regions selected from the Bacillus subtilis chromosome
Smith, H., de Jong, A., Bron, S.,Venema, G.
Gene 1988 ;70(2):351-361 1988 |
Cloning and characterization of a Bacillus subtilis transcription unit involved in ATP-dependent DNase synthesis
Kooistra, J., Vosman, B.,Venema, G.
J Bacteriol 1988 ;170(10):4791-4797 1988 |
Cloning and characterization of the tetracycline resistance determinant of and several promoters from within the
conjugative transposon Tn919
Hill, C., Venema, G., Daly, C.,Fitzgerald, G. F.
Appl Environ.Microbiol 1988 ;54(5):1230-1236 1988 |
Deletion analysis of the proteinase gene of Streptococcus cremoris Wg2
Kok, J., Hill, D., Haandrikman, A. J., de Reuver, M. J., Laan, H.,Venema, G.
Appl Environ.Microbiol 1988 ;54(1):239-244 1988 |
Effect of plasmid incompatibility on DNA transfer to Streptococcus cremoris
van der Lelie, D., van der Vossen, J.M.B.M., Venema, G.
Appl Environ.Microbiol 1988 ;54(0):865-871 1988 |
Genetics of proteinases of lactic acid bacteria
Kok, J., Venema, G.
Biochimie 1988 ;70(4):475-488 1988 |
Instability of recombinant pUB110 plasmids in Bacillus subtilis: plasmid-encoded stability function and effects of
DNA inserts
Bron, S., Luxen, E.,Swart, P.
Plasmid 1988 ;19(3):231-241 1988 |
Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2
Kok, J., Leenhouts, K. J., Haandrikman, A. J., Ledeboer, A. M.,Venema, G.
Appl Environ.Microbiol 1988 ;54(1):231-238 1988 |
Plasmid deletion formation in Bacillus subtilis
Peijnenburg, A. A. C. M., Bron, S.,Venema, G.
Plasmid 1988 ;20(1):23-32 1988 |
Restriction and modification in Bacillus subtilis Marburg 168: target sites and effects on plasmid transformation
Bron, S., Janniere, L.,Ehrlich, S. D.
Mol Gen.Genet 1988 ;211(1):186-189 1988 |
Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats
Peeters, B. P., de Boer, J. H., Bron, S.,Venema, G.
Mol Gen.Genet 1988 ;212(3):450-458 1988 |
Synthesis and processing of Escherichia coli TEM-beta-lactamase and Bacillus licheniformis alpha-amylase in E.
coli: the role of signal peptidase I
van Dijl, J. M., Smith, H., Bron, S.,Venema, G.
Mol Gen.Genet 1988 ;214(1):55-61 1988 |
Transformation in Bacillus subtilis: involvement of the 17-kilodalton DNA-entry nuclease and the
competence-specific 18-kilodalton protein
Vosman, B., Kuiken, G., Kooistra, J.,Venema, G.
J Bacteriol 1988 ;170(8):3703-3710 1988 |
Transfomation of group A streptococci by electroporation
Suvorov, A., Kok, J., Venema, G.
FEMS Microbiology Letters 1988 ;56(0):95-100 1988 |
Liposome-enhanced transformation of Streptococcus lactis and plasmid transfer by intergeneric protoplast fusion of
Streptococcus lactis and Bacillus subtilis
Vossen, van der, J.M.B.M., Kok, J., Lelie, van der D., Venema, G.
FEMS Microbiology Letters 1988 ;49(0):323-329 1988 |
A general method for the construction of Escherichia coli mutants by homologous recombination and plasmid
segregation
Kiel, J. A., Vossen, J. P.,Venema, G.
Mol Gen.Genet 1987 ;207(2):294-301 1987 |
Bacillus subtilis generates a major specific deletion in pAM beta 1
van der Lelie, D., Venema, G.
Appl Environ.Microbiol 1987 ;53(10):2458-2463 1987 |
Cloning in Escherichia coli of the gene specifying the DNA-entry nuclease of Bacillus subtilis
Vosman, B., Kooistra, J., Olijve, J.,Venema, G.
Gene 1987 ;52(2):175-183 1987 |
Construction and use of signal sequence selection vectors in Escherichia coli and Bacillus subtilis
Smith, H., Bron, S., van Ee, J.,Venema, G.
J Bacteriol 1987 ;169(7):3321-3328 1987 |
Improving starter cultures.
Venema, G., Kok. J.
Trends in Biotechnology. 1987 ;5(0):144-149 1987 |
Isolation and characterization of Streptococcus cremoris Wg2-specific promoters
van der Vossen, J. M. B. M., van der Lelie, D.,Venema, G.
Appl Environ.Microbiol 1987 ;53(10):2452-2457 1987 |
Stability function in the Bacillus subtilis plasmid pTA 1060
Bron, S., Bosma, P., van Belkum, M. J.,Luxen, E.
Plasmid 1987 ;18(1):8-15 1987 |
Structural plasmid instability in recombination- and repair-deficient strains of Bacillus subtilis
Peijnenburg, A. A. C. M., Bron, S.,Venema, G.
Plasmid 1987 ;17(2):167-170 1987 |
The cell wall-associated proteases of Streptococcus cremoris Wg2.
Hugenholtz, J., van Sinderen, J., Kok, J., Konings, W.N.
Appl Environ.Microbiol 1987 ;53(0):853-859 1987 |
The effect of restriction on shotgun cloning and plasmid stability in Bacillus subtilis Marburg
Haima, P., Bron, S.,Venema, G.
Mol Gen.Genet 1987 ;209(2):335-342 1987 |
Integration of vector-containing Bacillus subtilis chromosomal DNA by a Campbell-like mechanism
Vosman, B., Kooistra, J., Olijve, J.,Venema, G.
Mol Gen.Genet 1986 ;204(3):524-531 1986 |
Cloning and expression of a Streptococcus cremoris proteinase in Bacillus subtilis and Streptococcus lactis
Kok, J., van Dijl, J. M., van der Vossen, J. M. B. M.,Venema, G.
Appl Environ.Microbiol 1985 ;50(1):94-101 1985 |
Construction of cloning, promoter-screening, and terminator-screening shuttle vectors for Bacillus subtilis and
Streptococcus lactis
van der Vossen, J. M. B. M., Kok, J.,Venema, G.
Appl Environ.Microbiol 1985 ;50(2):540-542 1985 |
Effect of concentration on the subsequent fate of plasmid DNA in human fibroblasts
Mooibroek, H., Arnberg, A. C., de Jong, B.,Venema, G.
Mol Gen.Genet 1985 ;199(1):82-88 1985 |
Segregational instability of pUB110-derived recombinant plasmids in Bacillus subtilis
Bron, S., Luxen, E.
Plasmid 1985 ;14(3):235-244 1985 |
Transformation in Bacillus subtilis: further characterization of a 75,000-dalton protein complex involved in
binding and entry of donor DNA
Smith, H., Wiersma, K., Venema, G.,Bron, S.
J Bacteriol 1985 ;164(1):201-206 1985 |
Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and
Escherichia coli
Kok, J., van der Vossen, J. M. B. M.,Venema, G.
Appl Environ.Microbiol 1984 ;48(4):726-731 1984 |
Direct plasmid transfer from replica-plated E. coli colonies to competent B. subtilis cells. Identification of an
E. coli clone carrying the hisH and tyrA genes of B. subtilis
van Randen, J., Venema, G.
Mol Gen.Genet 1984 ;195(1):57-61 1984 |
Genetic manipulation of the restricted facultative methylotroph Hyphomicrobium X by the R-plasmid-mediated
introduction of the Escherichia coli pdh genes
Dijkhuizen, L., Harder, W., de Boer, L., van Boven, A., Clement, W., Bron, S.,Venema, G.
Arch.Microbiol 1984 ;139(4):311-318 1984 |
Heterospecific transformation in Bacillus subtilis: protein composition of a membrane-DNA complex containing
unstable heterologous donor-recipient complex
te Riele, H. P., Venema, G.
Mol Gen.Genet 1984 ;197(3):478-485 1984 |
Involvement of single-strand breaks in complex formation between single-stranded DNA and nucleoids of Bacillus
subtilis
van Randen, J., Wiersma, K.,Venema, G.
Mol Gen.Genet 1984 ;193(3):500-506 1984 |
Isolation and characterization of Bacillus subtilis mutants altered in competence
Fani, R., Mastromei, G., Polsinelli, M.,Venema, G.
J Bacteriol 1984 ;157(1):152-157 1984 |
Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis: further characterization of unstable
association between donor and recipient DNA and the involvement of the cellular membrane
te Riele, H. P., Venema, G.
Mol Gen.Genet 1984 ;195(1):200-208 1984 |
Repair of UV damage in plasmid DNA by human fibroblasts
Mooibroek, H., de Jong, B.,Venema, G.
Mol Gen.Genet 1984 ;195(1):175-179 1984 |
Restriction of hemimethylated DNA by the Bacillus subtilis R system
Bron, S., Luxen, E.,Venema, G.
Mol Gen.Genet 1984 ;195(1):370-373 1984 |
Transformation in Bacillus subtilis: a 75,000-dalton protein complex is involved in binding and entry of donor DNA
Smith, H., Wiersma, K., Venema, G.,Bron, S.
J Bacteriol 1984 ;157(3):733-738 1984 |
Characterization of a conditionally transformation-deficient mutant of Haemophilus influenzae that carries a
mutation in the rec-1 gene region
Kooistra, J., van Boxel, T.,Venema, G.
J Bacteriol 1983 ;153(2):852-860 1983 |
Cloning and expression of the Escherichia coli recA gene in Bacillus subtilis
de Vos, W. M., de Vries, S. C.,Venema, G.
Gene 1983 ;25(2):301-308 1983 |
Inhibition of DNA replication by transformation in a Haemophilus influenzae mutant carrying an altered Rec-1
protein
Kooistra, J., van Boxel, T.,Venema, G.
J Bacteriol 1983 ;154(2):686-692 1983 |
Introduction of a Streptococcus cremoris plasmid in Bacillus subtilis
Vosman, B., Venema, G.
J Bacteriol 1983 ;156(2):920-921 1983 |
Resistance of bacteriophage H1 to restriction and modification by Bacillus subtilis R
Bron, S., Luxen, E.,Venema, G.
J Virol. 1983 ;46(3):703-708 1983 |
Transformation in Bacillus subtilis: properties of DNA-binding-deficient mutants
Smith, H., de Vos, W.,Bron, S.
J Bacteriol 1983 ;153(1):12-20 1983 |
Transformation in Bacillus subtilis: purification and partial characterization of a membrane-bound DNA-binding
protein
Smith, H., Wiersma, K., Bron, S.,Venema, G.
J Bacteriol 1983 ;156(1):101-108 1983 |
Effect of 4,5',8-trimethylpsoralen interstrand cross-links present in recipient Bacillus subtilis on the
integration of transforming DNA
Mooibroek, H., van Randen, J.,Venema, G.
J Bacteriol 1982 ;152(2):669-675 1982 |
Initiation of recombination during transformation of Bacillus subtilis requires no extensive homologous sequences
van Randen, J., Wiersma, K.,Venema, G.
Mol Gen.Genet 1982 ;188(3):499-507 1982 |
Isolation and partial characterization of Bacillus subtilis mutants impaired in DNA entry
Mulder, J. A.Venema, G.
J Bacteriol 1982 ;150(1):260-268 1982 |
Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis. I. Processing of B. pumilus and B.
licheniformis DNA in B. subtilis
te Riele, H. P., Venema, G.
Genetics 1982 ;101(2):179-188 1982 |
Molecular fate of heterologous bacterial DNA in competent Bacillus subtilis. II. Unstable association of
heterologous DNA with the recipient chromosome
te Riele, H. P., Venema, G.
Genetics 1982 ;102(3):329-340 1982 |
Restriction and modification in Bacillus subtilis: effects on transfection under marker rescue conditions
Bron, S., Luxen, E.,Venema, G.
J Virol. 1982 ;42(2):357-364 1982 |
Role of proton motive force in genetic transformation of Bacillus subtilis
van Nieuwenhoven, M. H., Hellingwerf, K. J., Venema, G.,Konings, W. N.
J Bacteriol 1982 ;151(2):771-776 1982 |
The effect of chlorpromazine on transformation in Bacillus subtilis
Mooibroek, H.Venema, G.
Mol Gen.Genet 1982 ;185(1):165-168 1982 |
Transformation of Bacillus subtilis competent cells: identification of a protein involved in recombination
de Vos, W. M., Venema, G.
Mol Gen.Genet 1982 ;187(3):439-445 1982 |
Transformation-deficient mutants of Bacillus subtilis impaired in competence-specific nuclease activities
Mulder, J. A.Venema, G.
J Bacteriol 1982 ;152(1):166-174 1982 |
Unstable association in vitro between donor and recipient DNA in Bacillus subtilis
van Randen, J., Wiersma, K.,Venema, G.
J Bacteriol 1982 ;152(1):275-283 1982 |
Assimilation of single-stranded donor deoxyribonucleic acid fragments by nucleoids of competent cultures of
Bacillus subtilis
van Randen, J., Venema, G.
J Bacteriol 1981 ;145(3):1177-1188 1981 |
Effect of ethylenediaminetetraacetic acid on deoxyribonucleic acid entry and recombination in transformation of a
wild-type strain and a rec-1 mutant of Haemophilus influenzae
Noteborn, M., Venema, G.,Kooistra, J.
J Bacteriol 1981 ;145(3):1189-1195 1981 |
Fate of plasmid DNA in transformation of Bacillus subtilis protoplasts
de Vos, W. M., Venema, G.
Mol Gen.Genet 1981 ;182(1):39-43 1981 |
Inactivation of transforming Bacillus subtilis deoxyribonucleic acid by monoadducts of 4,5',8-trimethylpsoralen
te Riele, H. P., van Sluis, P.,Venema, G.
J Bacteriol 1981 ;145(2):832-839 1981 |
Plasmid transformation in Bacillus subtilis: fate of plasmid DNA
de Vos, W. M., Venema, G., Canosi, U.,Trautner, T. A.
Mol Gen.Genet 1981 ;181(4):424-433 1981 |
Deoxyribonucleic acid-binding properties and membrane protein composition of a competence-deficient mutant of
Haemophilus influenzae
Kooistra, J., van Boxel, T.,Venema, G.
J Bacteriol 1980 ;144(1):22-27 1980 |
DNA binding and deoxyribonuclease activity in Bacillus subtilis during temperature-induced competence development
Espinosa, M., Joenje, H.,Venema, G.
J Gen.Microbiol 1980 ;121(1):79-84 1980 |
Properties of Haemophilus influenzae mutants that are slightly recombination deficient and carry a mutation in the
rec-1 gene region
Kooistra, J., Venema, G.
J Bacteriol 1980 ;142(3):829-835 1980 |
Purification and properties of the Bsu endonuclease
Bron, S., Horz, W.
Methods Enzymol. 1980 ;65(1):112-132 1980 |
Restriction and modification in B. subtilis: effects on transformation and transfection with native and
single-stranded DNA
Bron, S., Luxen, E., Venema, G.,Trautner, T. A.
Mol Gen.Genet 1980 ;179(1):103-110 1980 |
Restriction and modification in B. subtilis: the role of homology between donor and recipient DNA in transformation
and transfection
Bron, S., Luxen, E.,Trautner, T. A.
Mol Gen.Genet 1980 ;179(1):111-117 1980 |
The effect of trimethylpsoralen--crosslinks on entry of donor DNA in transformation and transfection of Bacillus
subtilis
Venema, G., Canosi, U.
Mol Gen.Genet 1980 ;179(1):1-11 1980 |
Bacterial transformation
Venema, G.
Adv.Microb Physiol. 1979 ;19(0):245-331 1979 |
An unstable donor-recipient DNA complex in transformation of Bacillus subtilis
Popowski, J.Venema, G.
Mol Gen.Genet 1978 ;166(2):119-126 1978 |
Transformation in Bacillus subtilis: characterization of an intermediate in recombination observed during
transformation
Buitenwerf, J., Venema, G.
Mol Gen.Genet 1978 ;160(1):67-75 1978 |
Characteristics of a complex formed by a nonintegrated fraction of transforming DNA and Bacillus subtilis recipient
cell constituents
Pieniazek, D., Piechowska, M.,Venema, G.
Mol Gen.Genet 1977 ;156(3):251-261 1977 |
Transformation in Bacillus subtilis: biological and physical evidence for a novel DNA-intermediate in synchronously
transforming cells
Buitenwerf, J., Venema, G.
Mol Gen.Genet 1977 ;156(2):145-155 1977 |
Transformation in bacillus subtilis: fate of transforming DNA in transformation deficient mutants
Buitenwerf, J., Venema, G.
Mol Gen.Genet 1977 ;151(2):203-213 1977 |
Effect of adenosine 5'-triphosphate-dependent deoxyribonuclease deficiency on properties and transformation of
Haemophilus influenzae strains
Kooistra, J., Venema, G.
J Bacteriol 1976 ;128(2):549-556 1976 |
Different nuclease activities in competent and noncompetent Bacillus subtilis
Joenje, H.Venema, G.
J Bacteriol 1975 ;122(1):25-33 1975 |
Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from competent and noncompetent
Bacillus subtilis
Joenje, H., Konings, W. N.,Venema, G.
J Bacteriol 1975 ;121(3):771-776 1975 |
Restriction and modification in B. subtilis. Nucleotide sequence recognised by restriction endonuclease R. Bsu R
from strain R
Bron, S., Murray, K.
Mol Gen.Genet 1975 ;143(1):25-33 1975 |
Restriction and modification in B. subtilis. Purification and general properties of a restriction endonuclease from
strain R
Bron, S., Murray, K.,Trautner, T. A.
Mol Gen.Genet 1975 ;143(1):13-23 1975 |
Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid
absorption in Bacillus subtilis: localization of uptake and of transport of transforming deoxyribonucleic acid in
competent cells
Vermeulen, C. A., Venema, G.
J Bacteriol 1974 ;118(2):342-350 1974 |
Electron microscope and autoradiographic study of ultrastructural aspects of competence and deoxyribonucleic acid
absorption in Bacillus subtilis: ultrastructure of competent and noncompetent cells and cellular changes during
development of competence
Vermeulen, C. A., Venema, G.
J Bacteriol 1974 ;118(2):334-341 1974 |
Fate of donor deoxyribonucleic acid in a highly transformation-deficient strain of Haemophilus influenzae
Kooistra, J., Venema, G.
J Bacteriol 1974 ;119(3):705-717 1974 |
Interactions between exogenous deoxyribonucleic acid and membrane vesicles isolated from Bacillus subtilis 168
Joenje, H., Konings, W. N.,Venema, G.
J Bacteriol 1974 ;119(3):784-794 1974 |
Protease-sensitive transfection of Bacillus subtilis with bacteriophage GA-1 DNA: a probable case of heterologous
transfection
Arwert, F., Venema, G.
J Virol. 1974 ;13(3):584-589 1974 |
Restriction and modification in B. subtilis. Biological aspects
Trautner, T. A., Pawlek, B., Bron, S.,Anagnostopoulos, C.
Mol Gen.Genet 1974 ;131(3):181-191 1974 |
Transfection of Bacillus subtilis with bacteriophage H1 DNA: fate of transfecting DNA and transfection enhancement
in B. subtilis uur+ and uur- strains
Arwert, F., Venema, G.
Mol Gen.Genet 1974 ;128(1):55-72 1974 |
Isolation and partial characterization of a temperature-sensitive mutant of Bacillus subtilis impaired in the
development of competence for genetic transformation
Joenje, H., Admiraal, W.,Venema, G.
J Gen.Microbiol 1973 ;78(1):67-77 1973 |
Poor transformability with novr and eryr donor DNA of some mitomycin-C-sensitive strains of Haemophilus influenzae
Kooistra, J., Venema, G.
Mutat.Res 1973 ;20(3):313-326 1973 |
Transformation in Bacillus subtilis. Fate of newly introduced transforming DNA
Arwert, F., Venema, G.
Mol Gen.Genet 1973 ;123(2):185-198 1973 |
Stimulation of the development of competence by culture fluids in Bacillus subtilis transformation
Joenje, H., Gruber, M.,Venema, G.
Biochim.Biophys.Acta 1972 ;262(2):189-199 1972 |
The effect of competence regime on competence, DNA absorption and integration of DNA in cultures of Bacillus
subtilis
Vermeulen, C. A., Venema, G.
J Gen.Microbiol 1972 ;71(3):415-424 1972 |
Ultraviolet inactivation and excision-repair in Bacillus subtilis. 3. Sensitized photoinactivation of transforming
DNA, and the effect of thymine dimers on differential marker inactivation and differential marker repair
Bron, S., Venema, G.
Mutat.Res 1972 ;15(4):377-393 1972 |
Ultraviolet inactivation and excision-repair in Bacillus subtilis. I. Construction and characterization of a
transformable eightfold auxotrophic strain and two ultraviolet-sensitive derivatives
Bron, S., Venema, G.
Mutat.Res 1972 ;15(1):1-10 1972 |
Ultraviolet inactivation and excision-repair in Bacillus subtilis. II. Differential inactivation and differential
repair of transforming markers
Bron, S., Venema, G.
Mutat.Res 1972 ;15(1):11-22 1972 |
Ultraviolet inactivation and excision-repair in Bacillus subtilis. IV. Integration and repair of
ultraviolet-inactivated transforming DNA
Bron, S., Venema, G.
Mutat.Res 1972 ;15(4):395-409 1972 |
Autoradiographic estimation of competence and the relationship between competence and transformability in cultures
of Bacillus subtilis
Vermeulen, C. A., Venema, G.
J Gen.Microbiol 1971 ;69(2):239-252 1971 |
In vitro excision-repair of ultraviolet-irradiated transforming DNA from Bacillus subtilis
Heijneker, H. L., Pannekoek, H., Oosterbaan, R. A., Pouwels, P. H., Bron, S., Arwert, F.,Venema, G.
Proc Natl Acad Sci U S A 1971 ;68(12):2967-2971 1971 |
Fate of donor DNA in some poorly transformable strains of Haemophilus influenzae
Kooistra, J., Venema, G.
Mutat.Res 1970 ;9(3):245-253 1970 |
Penetration of thymine-starved bacterial DNA during transformation of B. subtilis 168 T-
Sicard, N.Venema, G.
Biochem Biophys.Res Commun. 1969 ;36(4):647-650 1969 |
Evidence for the involvement of membranous bodies in the processes leading to genetic transformation in Bacillus
subtilis
Wolstenholme, D. R., Vermeulen, C. A.,Venema, G.
J Bacteriol 1966 ;92(4):1111-1121 1966 |